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Petrogenesis of Quebrada de la Mina and Altar North porphyries (Cordillera of San Juan, Argentina): Crustal assimilation and metallogenic implications

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Geoscience Frontiers 2017年第5期8卷 1135-1159页

作者： Laura Maydagán Marta Franchini Massimo Chiaradia Verónica Bouhier Noelia Di Giuseppe roger rey Luis Dimieri Centro Patagónico de Estudios Metalogenéticos-CONICET Argentina INGEOSUR-CONICET Departamento de Geología Universidad Nacional del Sur San Juan 670 8000 Bahía Blanca Argentina Instituto de Investigación en Paleobiología y Geología Universidad Nacional de Río Negro Av. Roca 1242 8332 Roca Argentina Departamento de Geología y Petróleo Facultad de Ingeniería Universidad Nacional del Comahue Buenos Aires 1400 8300 Neuquén Argentina Section of Earth and Environmental Sciences University of Geneva Switzerland Minera Peregrine Argentina S.A Santa Fe (Oeste) 117 Piso 4B Edificio Derby Ciudad San Juan Argentina

We investigate the geology of Altar North(Cu-Au) and Quebrada de la Mina(Au) porphyry deposits located in San Juan Province(Argentina), close to the large Altar porphyry copper deposit(995 Mt,0.35% Cu, 0.083 g/t Au), to present constraints on the magmatic processes that occurred in the parental magma chambers of these magmatic-hydrothermal systems. Altar North deposit comprises a plagioclase-amphibole-phyric dacite intrusion(Altar North barren porphyry) and a plagioclaseamphibole-biotite-phyric dacite stock(Altar North mineralized porphyry, 11.98 ± 0.19 Ma). In Quebrada de la Mina, a plagioclase-amphibole-biotite-quartz-phyric dacite stock(QDM porphyry,11.91±0.33 Ma) crops out. High Sr/Y ratios(92-142) and amphibole compositions of Altar North barren and QDM porphyries reflect high magmatic oxidation states(fO_2= NNO+1.1 to+1.6) and high fH_2O conditions in their magmas. Zones and rims enriched in anorthite(An_(37-48))), SrO(0.22-0.33 wt.%)and FeO(0.21-0.37 wt.%) in plagioclase phenocrysts are evidences of magmatic recharge processes in the magma chambers. Altar North and Quebrada de la Mina intrusions have relatively homogeneous isotopic compositions(^(87)Sr/^(86)Sr_(t)= 0.70450-0.70466, ε_(ND)(t) = +0.2 to +1.2) consistent with mixed mantle and crust contributions in their magmas. Higher Pb isotopes ratios(^(207)Pb/^(204)Pb=15.6276-15.6294) of these intrusions compared to other porphyries of the district, reflect an increase in the assimilation of high radiogenic Pb components in the magmas. Ages of zircon xenocrysts(297,210,204,69 Ma) revealed that the magmas have experienced assimilation of Miocene, Cretaceous, Triassic and Carboniferous crustal rocks.Fluids that precipitated sulfides in the Altar deposit may have remobilized Pb from the host rocks, as indicated by the ore minerals being more radiogenic(207Pb/204 Pb = 15.6243-15.6269) than their host intrusions. Au/Cu ratio in Altar porphyries(average Au/Cu ratio of 0.14 ×10^(-4)by weight in Altar Central)is higher than in the giant Miocene porphyry deposits

关键词： Porphyry High sulfidation epithermal Magmatic recharge Radiogenic isotopes Crustal assimilation Argentinian Andes

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Clustering of voltage-gated ion channels as an evolutionary trigger of myelin formation

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Neural Regeneration Research 2024年第8期19卷 1631-1632页

作者： Henrike Ohm Simone rey Christian Klambt Institut fur Neuro-und Verhaltensbiologie MunsterGermany

Neurons carry apical dendrites that perceive information and a basal axon that transmits the computed information towards its to rgets.The axon originates at the axon hillock which is followed by the axon initial segment.Here,action potentials are initiated that are based on millisecond long openings of specific voltagegated sodium and potassium channels that are conserved in all parahoxozoa(Placozoa,Cnidaria,Bilateria)(Li et al.,2015).

关键词： initiated carry potassium

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Insights on ZEB1-AS1: emerging role from cancer to neurodegeneration

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Neural Regeneration Research 2024年第6期19卷 1187-1188页

作者： Stephana Carelli Federica rey Erika Maghraby Cristina Cereda Pediatric Research Center “Romeo ed Enrica Invernizzi” Department of Biomedical and Clinical Sciences University of Milan 2. Center of Functional Genomics and Rare Diseases Department of Pediatrics Buzzi Children's Hospital Department of Biology and Biotechnology “L.Spallanzani” University of Pavia

Implications for lncRNAs in the central nervous system: Transcriptional dysregulation is a key contributor to the pathogenesis of a wide range of diseases and long non-coding RNAs(lncRNAs) are highly expressed in the nervous system. Indeed, amongst the over 50,000 lncRNAs expressed in the human genome, more than 40% are specifically expressed in the brain where their roles in brain development, neuron functions, maintenance,

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A sphingolipid message promotes neuronal health across generations

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Neural Regeneration Research 2024年第11期19卷 2325-2326页

作者： Wenyue Wang roger Pocock Development and Stem Cells Program Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental BiologyMonash UniversityMelbourneVICAustralia

Maternal nutrition can affect brain function of offspring in later life(Fitzgerald et al.,2020).Emerging studies have also shown that the maternal environment can modify susceptibility to neurodegenerative disease(Boots et al.,2023).Transmission of environmental information from mother to offspring depends on maternal nutrient provisioning.In the nematode Caenorhabditis elegans,maternal yolk,which is synthesized in the intestine and transferred to nourish oocytes and early embryos,can provide extranuclear inheritance factors to mediate phenotypic plasticity across generations.However,the molecular mechanisms of regulating such intergenerational effects remain largely unknown.

关键词： mother intestine transferred

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Making topological protein links using enzymatic reactions

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National Science Review 2024年第3期11卷 50-51页

作者： roger Castells-Graells Todd O.Yeates Department of Chemistry and Biochemistry University of California UCLA-DOE Institute for Genomics and Proteomics

Proteins are exceedingly complex molecules though, at their heart, they are essentially linear polymers. Pull at their ends and one obtains an extended backbone. While that is true in most cases, some natural proteins... 详细信息

关键词： DESIGN

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Tuberculosis Prevalence Trends from a Predictive Modelling Study-10 High-Burden Countries,1980-2035

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China CDC weekly 2024年第12期6卷 225-229,I0001,I0002页

作者： Qiuping Chen Qiao Liu Kangguo Li Laurent Gavotte roger Frutos Tianmu Chen CIRAD IntertrypMontpellierFrance Universitéde Montpellier MontpellierFrance State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics National Innovation Platform for Industry-Education Integration in Vaccine ResearchXiamen UniversityXiamen CityFujian ProvinceChina State Key Laboratory of Vaccines for Infectious Diseases Xiang An Biomedicine LaboratorySchool of Public HealthXiamen UniversityXiamen CityFujian ProvinceChina Espace-Dev Universitéde MontpellierMontpellierFrance

What is already known about this topic?Given the challenges presented by drug-resistant strains of tuberculosis(TB)and the rising mobility of the population,achieving the objective of eradicating TB appears uncertain.What is added by this report?The examination of TB incidence trends in 10 highburden countries(HBCs)indicated a steady rise in cases,with India and China jointly accounting for nearly 70%of the burden.Projections for the future show diverse trajectories in these countries,with potential difficulties in reaching the TB elimination target,especially in Nigeria,Congo,and South Africa.What are the implications for public health practice?The number of TB cases is on the rise.It is crucial to learn from successful strategies to improve TB prevention and control worldwide through collaborative efforts.

关键词： tuberculosis uncertain Tuberculosis

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Mechanistic modeling of copper corrosions in data center environments

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Building Simulation 2024年第3期17卷 483-492页

作者： Rui Zhang Jianshun Zhang roger Schmidt Jeremy L.Gilbert Department of Mechanical and Aerospace Engineering College of Engineering and Computer ScienceSyracuse UniversitySyracuseNY13244USA Buildings and Transportation Science Division Oak Ridge National LaboratoryOak RidgeTN37830USA SyracuseCoE-New York Center of Excellence in Environmental and Energy Systems Syracuse University727 E.Washington StreetSyracuseNY13244USA Department of Bioengineering Clemson UniversityClemson-Medical University of South Carolina Bioengineering ProgramCharlestonSC29425USA

Air-side economizers are increasingly used to take advantage of“free-cooling”in data centers with the intent of reducing the carbon footprint of buildings.However,they can introduce outdoor pollutants to indoor environment of data centers and cause corrosion damage to the information technology equipment.To evaluate the reliability of information technology equipment under various thermal and air-pollution conditions,a mechanistic model based on multi-ion transport and chemical reactions was developed.The model was used to predict Cu corrosion caused by Cl_(2)-containing pollutant mixtures.It also accounted for the effects of temperature(25℃and 28℃),relative humidity(50%,75%,and 95%),and synergism.It also identified higher air temperature as a corrosion barrier and higher relative humidity as a corrosion accelerator,which agreed well with the experimental results.The average root mean square error of the prediction was 13.7Å.The model can be used to evaluate the thermal guideline for data centers design and operation when Cl_(2)is present based on pre-established acceptable risk of corrosion in data centers’environment.

关键词： chloride pollutant mixture copper corrosion model data center temperature relative humidity synergistic effect

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Recent Developments in Metallic Degradable Micromotors for Biomedical and Environmental Remediation Applications

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Nano-Micro Letters 2024年第3期16卷 1-35页

作者： Sourav Dutta Seungmin Noh roger Sanchis Gual Xiangzhong Chen Salvador Pané Bradley J.Nelson Hongsoo Choi Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea DGIST‑ETH Microrobotics Research Center DGISTDaegu 42988Republic of Korea Multi‑Scale Robotics Lab Institute of Robotics and Intelligent SystemsETH Zurich8092 ZurichSwitzerland Institute of Optoelectronics State Key Laboratory of Photovoltaic Science and TechnologyShanghai Frontiers Science Research Base of Intelligent Optoelectronics and PerceptionFudan UniversityShanghai 200433People’s Republic of China

Synthetic micromotor has gained substantial attention in biomedicine and environmental remediation.Metal-based degradable micromotor composed of magnesium(Mg),zinc(Zn),and iron(Fe)have promise due to their nontoxic fuel-free propulsion,favorable biocompatibility,and safe excretion of degradation products Recent advances in degradable metallic micromotor have shown their fast movement in complex biological media,efficient cargo delivery and favorable biocompatibility.A noteworthy number of degradable metal-based micromotors employ bubble propulsion,utilizing water as fuel to generate hydrogen bubbles.This novel feature has projected degradable metallic micromotors for active in vivo drug delivery applications.In addition,understanding the degradation mechanism of these micromotors is also a key parameter for their design and performance.Its propulsion efficiency and life span govern the overall performance of a degradable metallic micromotor.Here we review the design and recent advancements of metallic degradable micromotors.Furthermore,we describe the controlled degradation,efficient in vivo drug delivery,and built-in acid neutralization capabilities of degradable micromotors with versatile biomedical applications.Moreover,we discuss micromotors’efficacy in detecting and destroying environmental pollutants.Finally,we address the limitations and future research directions of degradable metallic micromotors.

关键词： Magnesium Zinc Iron Biodegradable microrobot Biomedical Environmental

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Exciton-polaritons in a 2D hybrid organic-inorganic perovskite microcavity with the presence of optical Stark effect

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Chinese Physics B 2024年第3期33卷 551-555页

作者： Kenneth Coker 郑楚媛 Joseph roger Arhin Kwame Opuni-Boachie Obour Agyekum 张伟利 School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu 611731China Department of Electrical and Electronic Engineering Ho Technical UniversityHo 00233Ghana Telecommunication Engineering Department Kwame Nkrumah University of Science and TechnologyKumasi 00233Ghana

This study investigates the properties of exciton-polaritons in a two-dimensional(2D)hybrid organic-inorganic perovskite microcavity in the presence of optical Stark effect.Through both steady and dynamic state analyses,strong coupling between excitons of perovskite and cavity photons is revealed,indicating the formation of polaritons in the perovskite microcavity.Besides,it is found that an external optical Stark pulse can induce energy shifts of excitons proportional to the pulse intensity,which modifies the dispersion characteristics of the polaritons.

关键词： exciton-polaritons perovskite microcavity optical Stark effect

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A framework for dynamic modelling of railway track switches considering the switch blades,actuators and control systems

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Railway Engineering Science 2024年第2期32卷 162-176页

作者： Saikat Dutta Tim Harrison Christopher Ward roger Dixon Phil Winship Institute of Thermofluids School of Mechanical EngineeringUniversity of LeedsLeedsWest YorkshireUK Wolfson School of Mechanical Electrical and Manufacturing EngineeringLoughborough UniversityLoughboroughLeicestershireUK Birmingham Centre for Railway Research and Education School of EngineeringUniversity of BirminghamBirminghamWest MidlandsUK Network Rail Milton KeynesBuckinghamshireUK

The main contribution of this paper is the development and demonstration of a novel methodology that can be followed to develop a simulation twin of a railway track switch system to test the functionality in a digital environment.This is important because,globally,railway track switches are used to allow trains to change routes;they are a key part of all railway networks.However,because track switches are single points of failure and safety-critical,their inability to operate correctly can cause significant delays and concomitant costs.In order to better understand the dynamic behaviour of switches during operation,this paper has developed a full simulation twin of a complete track switch system.The approach fuses finite element for the rail bending and motion,with physics-based models of the electromechanical actuator system and the control system.Hence,it provides researchers and engineers the opportunity to explore and understand the design space around the dynamic operation of new switches and switch machines before they are built.This is useful for looking at the modification or monitoring of existing switches,and it becomes even more important when new switch concepts are being considered and evaluated.The simulation is capable of running in real time or faster meaning designs can be iterated and checked interactively.The paper describes the modelling approach,demonstrates the methodology by developing the system model for a novel“REPOINT”switch system,and evaluates the system level performance against the dynamic performance requirements for the switch.In the context of that case study,it is found that the proposed new actuation system as designed can meet(and exceed)the system performance requirements,and that the fault tolerance built into the actuation ensures continued operation after a single actuator failure.

关键词： Railway track switch Mathematical modelling Redundant actuation Finite element analysis

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