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New variola(mpox)in Brazil:Epidemiological update and perspectives

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Asian Pacific Journal of Tropical Medicine 2022年第12期15卷 525-528页

作者： Ana Caroline Edwiges Evangelista Maria Eduarda Queiroz Santos Bandeira Larissa martins de Sena Williana de Paula Marli do Carmo Cupertino Andréia Patrícia Gomes rodrigo Siqueira-Batista School of Medicine Faculdade Dinâmica do Vale do PirangaPonte NovaMinas GeraisBrazil Departament of Medicine and Nursing Universidade Federal de ViçosaViçosaMinas GeraisBrazil

New variola(NV)-mpox(monkeypox)-is a zoonosis caused by the mpox virus,which belongs to the genus Orthopoxvirus in the family *** disease,in the present year(2022),has caused several cases and deaths around the world,including Brazil[1].The group of poxviruses,in which the species that causes NV is included,consists of agents widely distributed in *** to their considerably large size,they were among the first viruses to be microscopically *** Poxviridae family is capable of infecting epithelial and connective tissue ***,such a viral family is classified as a genome lineage composed of doublestranded DNA,completely independent of the host nucleus[1].

关键词： Brazil belongs considerably

Total segmental aplasia of uterus body in bitch

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Asian pacific Journal of Reproduction 2019年第1期8卷 43-44页

作者： Leonardo martins Leal Fábio rodrigo Castro Bastos Tais Harumi de Castro Sasahara Paola Castro Moraes Márcia Rita Fernandes Machado Centro Universitário Ingá-UNINGá MaringáPRBrazil Universidade de Sao Paulo-USP Sao PauloSPBrazil Universidade Estadual Paulista-Unesp JaboticabalSPBrazil

Congenital anomalies of the female tubular genital tract are rare and known as segmental aplasia, resulting from incomplete development of paramesonephric ducts during embryonic stage, which originate from the cranial portion of vagina, cervix, uterus and oviducts. In the literature consulted, several reports of uterine horn aplasia are described in bitches, however there is only one report described in the world literature on total aplasia of the body of the uterus. This study aimed to describe the case of a two years old bitch, no breed defined, with 12 kg of weight, with segmental aplasia of uterus body diagnosed during ovariohysterectomy. During surgery it was noted that the bitch had the ovaries and uterine horns in their anatomical position, however an aplasia was noted in the body of the uterus. It was also found that the uterine horns had liquid inside, suggesting hydrometra. It was concluded in this case that although segmental aplasia of the body of the uterus is rare and difficult to diagnose by maintaining normal cyclicity of the female, it should be considered in dogs that do not have bloody vaginal discharge in proestrus and can not become pregnant after natural coverage or artificial insemination.

关键词： Segmental aplasia Surgery Ovariohysterectomy Reproduction

G protein-coupled receptor 37(GPR37) emerges as an important modulator of adenosinergic transmission in the striatum

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Neural Regeneration Research 2019年第11期14卷 1912-1914页

作者： Xavier Morato rodrigo A. Cunha Francisco Ciruela Unitat de Farmacologia Departament Patologia i Terapeutica ExperimentalFacultat de MedicinaInstituto de Investigacion Biomedica de Bellvitge (IDIBELL)Universitat de BarcelonaL’Hospitalet de LlobregatBarcelonaSpainInstitut de NeurocienciesUniversitat de BarcelonaBarcelonaSpain (Morato X Ciruela F) Center for Neuroscience and Cell Biology (CNC)-Center for Neurosciences and Cell BiologyUniversity of CoimbraCoimbraPortugalFaculty of MedicineUniversity of CoimbraCoimbraPortugal

G protein-coupled receptor 37 (GPR37), also known as parkin associated endothelin-like (Pael) receptor, is an orphan G protein- coupled receptor, which suffers a defective parking ubiquitination in autosomal recessive Parkinson’s disease promoting its endoplasmic reticulum aggregation and stress, neurotoxicity and neuronal death (Takahashi and Imai, 2003). Interestingly, we have demonstrated previously that GPR37 heteromerizes with adenosine A2A receptor (A2AR) in the striatum (Morato et al., 2017;Sokolina et al., 2017).

关键词： G protein-coupled receptor 37(GPR37) important modulator adenosinergic transmission

Discontinuation of antiviral therapy in chronic hepatitis B patients

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World Journal of Clinical Cases 2021年第24期9卷 6979-6986页

作者： Renato Medas rodrigo Liberal Guilherme Macedo Department of Gastroenterology and Hepatology Centro Hospitalar Universitario de São JoãoPorto 4200-319Portugal

Nucleos(t)ide analogs(NUC)are the first-line therapy for patients with chronic hepatitis B(CHB)recommended by most current *** therapy decreases progression of liver disease,reduces the risk of liver-related complications,and improves the quality of life of patients with *** indefinite or long-term NUC therapy is usually recommended,this strategy raises several concerns,such as side-effects,adherence,costs,and patient willingness to stop *** data showed the feasibility,efficacy,and safety of stopping antiviral therapy in carefully selected CHB patients,leading to its incorporation in international *** who discontinue NUC have a higher likelihood of hepatitis B surface antigen(HBsAg)loss compared to patients who continue on *** pertaining endpoints allowing safety discontinuation of NUC therapy differ among international *** hepatitis B e antigen(HBeAg)-positive patients,durable HBeAg seroconversion is considered an acceptable treatment *** HBeAg-negative patients,some guidelines propose undetectability hepatitis B virus DNA for at least 2 or 3 years,while others consider HBsAg loss as the only acceptable *** patients who stop therapy should remain under strict clinical and laboratorial follow-up protocols to detect and manage relapses in a timely *** reliable predictor of relapse has been consistently identified to date,although quantitative HBsAg has been increasingly studied as a reliable biomarker to predict safe NUC discontinuation.

关键词： Chronic hepatitis B Finite therapy Hepatitis B surface antigen loss Relapse Retreatment

Biosolid Application to Agricultural Land a Contribution to Global Phosphorus Recycle： A Review

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Pedosphere 2017年第1期27卷 1-16页

作者： Silvana Irene TORRI rodrigo Studart CORRt Giancarlo RENELLA Department of Natural Resources and Environment School of Agriculture University of Buenos Aires Avenue San Martin 4453 Buenos Aires 1417 DSE (Argentina) University of Brasilia-UnB/PPGCA Campus Darcy Ribeiro Caixa Postal 04401 70910-970 DF (Brazil) Department of Agrifood Production and Environmental Sciences University of Florence Piazzale delle Caseine 18 Florence 50144 (Italy)

Phosphorus(P) is an essential nutrient required for plant *** population growth and rising global demand for food are expected to increase the demand for phosphate ***,high-quality phosphate rock reserves are progressively becoming *** of the increased pressure on P resources could be alleviated by recycling P present in ***,it is crucial to understand the dynamics of P in biosolid-amended soils,the effects of residual biosolid-borne P in soils,the way in which microorganisms may control P dynamics in biosolid-amended soils and the environmental implications of the use of biosolids as a source of *** research is needed to maximize biosolid-borne P uptake by crops and minimize its loss from biosolid-amended *** analysis of the microbiological control of P dynamics in biosolid-amended soils indicates interactions of biosolid P with other nutrients such as carbon(C) and nitrogen(N),suggesting that harmonization of the current regulation on the use of biosolids in agriculture,mainly based on total N and pollutant contents,is needed to better recycle P in agriculture.

关键词： anthropogenic P phosphate P availability P biogeocycle P uptake runoff P

Local Fourier Analysis of Multigrid Methods with Polynomial Smoothers and Aggressive Coarsening

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Numerical Mathematics(Theory,Methods and Applications) 2015年第1期8卷 1-21页

作者： James Brannick Xiaozhe Hu Carmen rodrigo Ludmil Zikatanov Department of Mathematics The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Mathematics Tufts University503 Boston Ave.MedfordMA 02155USA Department of Applied Mathematics University of ZaragozaC/Maria de Luna 350018ZaragozaSpain Institute of Mathematics and Informatics Bulgarian Academy of SciencesAcad.G.Bonchev Str.Bl.81113 SofiaBulgaria

We focus on the study of multigrid methods with aggressive coarsening and polynomial smoothers for the solution of the linear systems corresponding to finite difference/element discretizations of the Laplace *** local Fourier analysis we determine automatically the optimal values for the parameters involved in defining the polynomial smoothers and achieve fast convergence of cycles with aggressive *** also present numerical tests supporting the theoretical results and the heuristic *** methods we introduce are highly parallelizable and efficient multigrid algorithms on structured and semi-structured grids in two and three spatial dimensions.

关键词： Multigrid local Fourier analysis polynomial smoothers aggressive coarsening

Divergence in the ovipositional behavior of the Papilio glaucus group

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Insect Science 2008年第4期15卷 361-367页

作者： rodrigo J. Mercader J. Mark Scriber Department of Entomology Michigan State University East Lansing MI48824 USA

This study contrasts the ovipositional profiles of four members of the Papilio glaucus group, P. glaucus, P. multicaudatus, P. canadensis, and P. rutulus. We used seven choice oviposition bioassays containing leaves from hosts in seven plant families utilized by members of the P. glaucus group. Specifically, we contrast the overall ovipositional profiles of these species and their acceptance of a host in a novel plant family （Populus tremuloides： Salicaceae） and a host in a putatively ancestral host plant family （Liriodendron tulipifera： Magnoliaceae）. Significant differences were observed between the ovipositional profiles of P. glaucus and P. multicaudatus relative to each other and to P. canadensis and P. rutulus. In contrast, no significant differences were observed between the ovipositional profiles of P. canadensis and P. rutulus, which were also the only species that accepted P. tremuloides. Unlike the acceptance of P. tremuloides, the acceptance of L. tulipifera was present throughout the group despite the inability of the larvae of most species in the group to utilize this host. These results support the prediction of the ＂hierarchical threshold model＂ that ancestral host plants are likely to be retained in the ovipositional hierarchy while novel hosts should only be accepted by derived populations.

关键词： host preference insect-plant interactions Lepidoptera Papilionidae

Quantum effects on dislocation motion from ring-polymer molecular dynamics

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npj Computational Materials 2018年第1期4卷 198-203页

作者： rodrigo Freitas Mark Asta Vasily V.Bulatov Department of Materials Science and Engineering University of CaliforniaBerkeleyCA 94720USA Lawrence Livermore National Laboratory LivermoreCA 94550USA Materials Sciences Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA Department of Materials Science and Engineering Stanford UniversityStanfordCA 94305USA

Quantum motion of atoms known as zero-point vibration was recently proposed to explain a long-standing discrepancy between theoretically computed and experimentally measured low-temperature plastic strength of iron and possibly other metals with high atomic *** finding challenges the traditional notion that quantum motion of atoms is relatively unimportant in solids comprised of heavy *** we report quantum dynamic simulations of quantum effects on dislocation motion within the exact formalism of Ring-Polymer Molecular Dynamics(RPMD).To extend the reach of quantum atomistic simulations to length and time scales relevant for extended defects in materials,we implemented RPMD in the open-source code LAMMPS thus making the RPMD method widely available to the *** use our RPMD/LAMMPS approach for direct calculations of dislocation mobility and its effects on the yield strength ofα-*** simulation results establish that quantum effects are noticeable at temperatures below 50 K but account for only a modest(≈13% at T=0 K)overall reduction in the Peierls barrier,at variance with the factor of two reduction predicted earlier based on the more approximate framework of harmonic transition state *** results confirm that zero-point vibrations provide ample additional agitation for atomic motion that increases with decreasing temperature,however its enhancing effect on dislocation mobility is largely offset by an increase in the effective atom size,an effect known as quantum dispersion that has not been accounted for in the previous calculations.

关键词： theory quantum motion

A Review on Cooperative Robotic Arms with Mobile or Drones Bases

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International Journal of Automation and computing 2021年第4期18卷 536-555页

作者： Larona Pitso Ramalepa rodrigo S.Jamisola Jr. Botswana International University of Science and Technology Palapye 10071Botswana

This review paper focuses on cooperative robotic arms with mobile or drone bases performing cooperative tasks. This is because cooperative robots are often used as risk-reduction tools to human life. For example, they are used to explore dangerous places such as minefields and disarm explosives. Drones can be used to perform tasks such as aerial photography, military and defense missions,agricultural surveys, etc. The bases of the cooperative robotic arms can be stationary, mobile(ground), or drones. Cooperative manipulators allow faster performance of assigned tasks because of the available "extra hand". Furthermore, a mobile base increases the reachable ground workspace of cooperative manipulators while a drone base drastically increases this workspace to include the aerial *** papers in this review are chosen to extensively cover a wide variety of cooperative manipulation tasks and industries that use *** cooperative manipulation, avoiding self-collision is one of the most important tasks to be performed. In addition, path planning and formation control can be challenging because of the increased number of components to be coordinated.

关键词： Cooperative arms mobile manipulator aerial manipulator mobile base drone base cooperative tasks