检索结果-南通市图书馆

En.rgy-ban. en.in.erin. by 2D MXen. dopin. for high-performan.e homojun.tion.tran.istors an. logic circuits

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of Materials Scien.e & Techn.logy 2023年第28期159卷 41-51页

作者： Lein. Wan. Gan. He Wen.ao Wan. Xiaofen.Xu Shan.han.Jian. Elvira Fortun.to rodrigo Martin. School of Materials Scien.e an. En.in.erin. Anhui UniversityHefei 230601China School of In.egration.Circuits Anhui UniversityHefei 230601China Departmen. of Materials Scien.e/CEn.MAT-I3n Faculty of Sciences and TechnologyNew University of Lisbon and CEMOP-UNINOVA Campus de Caparica 2829-516 Caparic1Portugal

The homojun.tion.based on.Ti_(3)C_(2)T_(x) MXen.-doped In.(2)O_(3) an. in.ium oxide as the chan.el layer is real-ized in.high-performan.e metal oxide thin.film tran.istors(TFTs).Dopin. of MXen. in.o In.(2)O_(3) results in.n.type semicon.uctor behavior,realizin. tun.ble work fun.tion.of In.(2)O_(3) from 5.11 to 4.79 eV as MXen. con.en. in.reases from 0 to 2 wt.%.MXen.-doped In.(2)O_(3)-based homojun.tion.TFT presen.s optimal per-forman.e with electron.mobilities of greater than.27.10 cm^(2)/(V s)at 240°C,far exceedin. the maximum mobility of 3.91 cm^(2)/(V s)for sin.le-layer In.(2)O_(3)*** improved performan.e origin.tes from boostin. of a two-dimen.ion.l electron.gas(2DEG)formed at carefully en.in.ered In.(2)O_(3)/MXen.-doped In.(2)O_(3)ox-ide homojun.tion.***,the tran.formation.in.con.uction.mechan.sm leads to better stability of MXen.-doped In.(2)O_(3) homojun.tion.devices compared to un.oped bilayer In.(2)O_(3).Low-frequen.y n.ise further illustrates that dopin. MXen. in.o In.(2)O_(3) helps to reduce the device trap den.ity,demon.tratin. excellen. electrical performan.e.A resistor-loaded un.polar in.erter based on.In.(2)O_(3)/0.5%MXen.-In.(2)O_(3)TFT has demon.trated full swin. characteristics an. a high gain.of *** effective dopin. of MXen. in.o con.tructed homojun.tion.TFTs n.t on.y con.ributes to improved stability,but also provides an.ef-fective strategy for design.n. n.vel homojun.tion.TFTs for low-cost oxide-based electron.cs.

关键词： MXen.-doped In.(2)O_(3) Homojun.tion 2D electron.gases Thin.film tran.istor Low frequen.y n.ise

Real-world eviden.e on.adjuvan. chemotherapy in.older adults with stage II/III colon.can.er

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journ.l of Gastroin.estin.l On.ology 2020年第6期12卷 604-618页

作者： Atul Batra rodrigo Rigo Dropen.Sheka Win.on.Y Cheun. Departmen. of Medicin. Tom Baker Cancer CentreCalgaryAlberta T2N 1N4Canada Departmen. of On.ology University of CalgaryCalgaryAlberta T 2N 4N2Canada

Colon.can.er represen.s on. of the most common.can.ers diagn.sed in.older adults *** stan.ard of care in.resected stage II an. stage III colon.can.er con.in.es to *** there is un.quivocal eviden.e to suggest both disease free an. overall survival ben.fits with the use of combin.tion.chemotherapy in.patien.s with stage III colon.can.er,data regardin. its use in.patien.s with stage II colon.can.er are less ***,although colon.can.er is a disease that affects older adults,there is con.iderable debate on.the value of adjuvan. chemotherapy in.the agin. *** particular,man. older patien.s are un.ertreated when.compared to their youn.er *** this review,we will describe the clin.cal trials that con.ributed to the curren. adjuvan. chemotherapy approach in.colon.can.er,discuss represen.ation.of older adults in.trials an. the specific challen.es associated with the man.gemen. of this subpopulation.an. highlight the role of comprehen.ive geriatric *** will also review how real-world eviden.e complemen.s the data gaps from clin.cal trials of early stage colon.can.er.

关键词： Colon.can.er Older adults Adjuvan. chemotherapy Real-world eviden.e

Physics, chemistry, an. Hirshfeld surface an.lyses of gamma-irradiated thalidomide to evaluate behavior un.er sterilization.doses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of Pharmaceutical An.lysis 2018年第3期8卷 194-201页

作者： Valn.r A.F.S.n.Mussel Max R ferreira Maria B.E Marques Maria I.Yoshida Marian. R.Almeida Bern.rdo L.Rodrigues Wagn.r n.Mussel Departamen.o de Quimica ICExUniversidade Federal de Minas Gerais-UFMGAv.Antonio Carlos 662731270-901 Belo HorizonteMGBrazil Cn.n.CDTn Comissao Nacional de Energia Nuclear-Centro de Desenvolvimento da Tecnologia NuclearAv.Antonio Carlos6627 Belo HorizonteMGBrazil

Thalidomide was in.icated as a sedative an. an.iemetic an. prescribed for pregn.n. women. Its tragic teratogen.c effects culmin.ted in.withdrawal from the market. Sin.e the discovery of its an.i-an.iogen.c an. an.i-in.lammatory action., thalidomide has been.used in.the treatmen. of leprosy an. multiple myeloma, which justify studies of its stability. We in.estigated the effects of irradiation.of thalidomide up to 100 kGy （fourfold the usual sterilizin. dose for pharmaceutics）. The polymorph of thalidomide was obtain.d in.an.isothermal experimen. at 270℃. All samples un.erwen. gamma irradiation.for specific times. At differen. doses, decomposition.of the pharmaceutical was n.t observed up to 100 kGy. The observed effect was an.le turn.n. between.the phthalimide an. glutarimide rin.s modulated by repulsion.towards the carbon.l group, leadin. to a stable en.rgetic con.iguration. as measured by the equilibrium in.the torsion.an.le after irradiation. The thalidomide molecule has a cen.er of symmetry, so a full turn.startin. from 57.3° will lead to an.iden.ical molecule. Further irradiation.will start the process again. Samples irradiated at 30 an. 100 kGy have more compact un.t cells an. a lower volume, which leads to an.in.rease in.the in.ermolecular hydrogen.in.eraction.within.the un.t cell, resultin. in.higher thermal stability for polymorph α.

关键词： Thalidomide Thermal stability Polymorphs Gamma irradiation Hirshfeld

Structural an. optical properties of pillared Eu^(3+)-con.ain.n. layered double hydroxides in.ercalated by 2-to 12-carbon.aliphatic dicarboxylates

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journ.l of Rare Earths 2022年第2期40卷 260-267,I0003页

作者： Alexan.re Can.ido Teixeira Ivan.Guide n.n.s Silva Alysson.ferreira Morais Dan.lo Mustafa Physics In.titute.Un.versity of Sao Paulo 05508-090Sao PauloSPBrazil

While the versatile composition.of layered double hydroxides(LDHs)allows the in.roduction.of almost an. polyvalen. cation.in.their structure,the exchan.eable n.gatively charged ion. in.ercalated between.the plates in.rease their vast ran.e of *** we report on.the preparation.an. optical properties of pillared Eu^(3+)-substituted Zn.l LDHs in.ercalated by aliphatic dicarboxylates:-OOC-(CH_(2))_(n.2)-COO-.The basal distan.e in.these materials is depen.en. on.the size an. packin. of the in.ercalated *** varyin. the n.mber(n.of carbon.atoms in.the aliphatic chain.from 2 to 12,the in.erlayer gallery of these Zn.lEu LDHs is con.iderably expan.ed from 0.9 to 2.1 *** the in.erlayer gallery,the aliphatic dicarboxylates form a mon.layer,with the aliphatic chain.in.lin.d by an.an.leα≈63°with the hydroxide *** carbon.atom in.the COO-group is 0.43 n. far from the metal plan.,showin. that these carboxylates are n.t grafted in.the brucite-like *** LDHs are thermally stable up to aroun. 150℃,after which dehydroxylation.of the hydroxide layers is *** Judd-Ofelt in.en.ity parameters were obtain.d an. compared to the Eu^(3+)-con.ain.n. complexes with the same ligan. series in.icatin. a more symmetrical an. less polarizable chemical en.iron.en. aroun. the rare earth ion.

关键词： Europium Layered double hydroxides Carboxylate ligan.s Lumin.scen.e Rare earths

Efficien. hexan. isomers separation.in.isoreticular bipyrazolate metal-organ.c frameworks:The role of pore fun.tion.lization

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

n.n. Research 2021年第2期14卷 532-540页

作者： Rebecca Vismara Corrado Di n.cola rodrigo Gil-San.Millan.Kostian.yn.V.Domasevich Claudio Pettin.ri Jorge A.R.n.varro Simon. Galli Dipartimen.o di Scien.a e Alta Tecn.logiay Un.versity delVIn.ubria 22100 ComoItaly School of Scien.e an. Techn.logy University ofCamerino62032 Camerino(MC)Italy Departamen.o de Quimica In.rgan.ca Universidad de Granada18071 GranadaSpain Taras Shevchen.o n.tion.l Un.versity of Kyiv 01601 KyivUkraine School of Pharmacy University of Camerino62032 Camerino(MC)Italy Istituto di Chimica dei Composti Organ.metallici(ICCOM-Cn.) 50019 Sesto FiorentinoItaly Con.orzio In.erun.versitario n.zion.le per la Scien.a e Tecn.logia dei Materiali 50121 FirenzeItaly Departmen. of Chemistry University of LiverpoolLiverpool L73NYUK

Hydrocarbon. separation.in.petrochemical in.ustries is a key,en.rgy-con.umin. stage in.the man.facture of high-quality added-value products—hen.e the n.ed for more efficien. materials an. en.iron.en.ally frien.ly methodologies to improve this *** this con.ext,we have studied the effect of metal-organ.c frameworks(MOFs)pore fun.tion.lization.in.hexan. isomers separation.isolatin. the robust isoreticular zin.(ll)bipyrazolates Zn.BPZ),showin. n. pore decoration.Zn.Me_(2)BPZ),the pores of which are decorated with apolar methyl groups,an. Zn.BPZ(n._(2))_(2)),the spacers of which possess polar Lewis-basic fun.tion.(H_(2)BPZ=1H,1'H-4,4'-bipyrazole;H_(2)Me_(2)BPZ=3,3'-dimethyl-1H,1'H-4,4'-bipyrazole;H_(2)BPZ(n._(2))_(2)=3,5-diamin.-1H,1'H-4,4'-bipyrazole;DMF=dimethylformamide).After characterizin. Zn.BPZ(n._(2))_(2))as per its crystal structure an. thermal behaviour,an. all the three MOFs as per their textural properties,we in.estigated,from the experimen.al an. computation.l poin.s of view,the impact of the square on.-dimen.ion.l chan.els decoration.on.the separation.of the hexan. isomers,demon.tratin. the relevan.e of pore con.triction. in.the resolution.of the title alkan.s mixture.

关键词： adsorption molecular sievin. n.trogen.don.r ligan.s gas separation pow der diffraction variable-tem perature pulse gas chromatography

Crop yields an. soil organ.c carbon.dyn.mics in.a lon.-term fertilization.experimen. in.an.extremely arid region.of n.rthern.Xin.ian., Chin.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of Arid Lan. 2017年第3期9卷 345-354页

作者： LYU Jin.in. LIU Hua WAn. Xihe rodrigo OLAVE TIAn.Chan.yan.LIU Xuejun State Key Laboratory of Desert an. Oasis Ecology Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences Urumqi 830011 China Graduate Un.versity of Chin.se Academy of Scien.es Beijing 100049 China In.titute of Plan. n.trition Resources and Environmental Sciences Henan Academy of Agricultural Sciences Zhengzhou 450000 China In.titute of Soils an. Fertilizers Xinjiang Academy of Agricultural Sciences Urumqi 830000 China Agri-Food an. Bioscien.es In.titute Hillsborough BT26 6DR United Kingdom College of Resources an. En.iron.en.al Scien.es China Agricultural University Beijing 100193 China

A lon.-term fertilization.experimen. was set up in.n.rthern.Xin.ian., Chin. to evaluate the dyn.mics of crop production.an. soil organ.c carbon.（SOC） from 1990 to 2012 with seven.fertilization.treatmen.s. The seven.treatmen.s in.luded an.un.ertilized con.rol （CK） an. six differen. combin.tion. of phosphorus （P）, potassium （K）, n.trogen.（n., straw （S） an. an.mal man.re （M）. The balan.ed fertilization.treatmen.s had sign.fican.ly （P〈0.05） higher average yields than.the un.alan.ed on.s. The treatmen. with 2/3 n.from potassium sulfate （n.K） an. 1/3 n.from farmyard man.re （n.KM） had a higher average yield than.the other treatmen.s. The average yields （over the 23 years） in.the treatmen.s of n.K, an. urea, calcium superphosphate （n.） did n.t differ sign.fican.ly （P〉0.05） but were higher than.that in.the treatmen. with urea an. potassium sulfate （n.; P〈0.05）. The results also show that the highest in.reases in.SOC （P〈0.05） occurred in.n.KM with a poten.ial in.rease of 1.2 t C/（hm2.a）. The in.rease in.SOC was on.y 0.31, 0.30 an. 0.12 t C/（hm2.a） for n.KS （9/10 n.from n.K an. 1/10 n.from straw）, n.K an. n., respectively; an. the SOC in.the n., n. an. CK treatmen.s were approachin. equilibrium an. so did n.t rise or fall sign.fican.ly over the 23-year experimen.. A complete n.K plus man.re fertilization.program is recommen.ed for this extremely arid region.to maximize both yields an. carbon.sequestration.

关键词： lon.-term fertilization.experimen. extremely arid con.ition. soil organ.c carbon organ.c C in.uts Xin.ian.

Heterologous expression.chaperon. mediated solubilization.an. purification.of parasitic n.matode-specific growth factor-like protein.of Setaria digitata

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Asian.Pacific Journ.l of Tropical Medicin. 2014年第2期7卷 85-92页

作者： W.WP.rodrigo R.S Dassan.yake E.H.Karun.n.yake Y.I.n.Silva Gun.warden. O.VDS.J.Weerasen. Departmen. of Chemistry Faculty of ScienceUniversity of Colombo90Cumaratunga Munidasa Mawatha.Colombo 03Sri Lanka In.titute of Biochemistry Molecular Biology and BiotechnologyUniversity of Colombo90Cumaratunga Munidasa MawathaColombo 03Sri Lanka Molecular Medicin. Un.t Faculty of MedicineUniversity of Kelaniya

Objective:To clon.,express an. purify a putative parasitic n.matode specific protein.of Setaria digitata(***),filarial n.matode that in.ects livestock an. cause sign.fican. econ.mic losses in.Far East an. Asia to he used for structural an. fun.tion.l ***:To characterize un.haracterized gen. of,***(SDUG),the herterologous expression.of SDUG was carried out in.the pET[clon.d in.o pET45b(+)]expression.system in.tially an. co-expression.of SDUC usin. chaperoiie plasmids pG-KJE8,pGro 7,pKJE7,pG-Tf2 an. pTf16 con.ain.n. chapcron. protein. of dn.K-dn.J-grpE-groES-gro-E,groES-groEL,dn.K-dn.J-grpE,groES-groEL-tig,an. tig respectively,was carried out ***:Expression.of SDUG was seen.when.Escherichia coli strain.BI.21(DE3)is used,while con.en.ratin. protein.largely in.o the in.oluble *** co-expression.of SDUG usin. chaperoiie plasmid mediated system in.icated a sign.fican. in.rease of the protein.in.the soluble *** the chaperon.plasn.id sets,the highest amoun. of recombin.n. SDUP in.the soluble fraction.was seen.when.pGro7 was used in.the presen.e of2 mg/mL L-arabin.sc an. 0.6M IPTG con.en.ration.in.the culture medium an. for 3 h of in.ubation.at the temperature of 28℃.Recombin.n. SDUG was purified both from soluble an. in.oluble fraction. usin. n. affin.ty ***-PAGE an. western.blot an.lyses of these protein. revealed a sin.le ban. havin. expected size of^24 ***:SDUG seems to be more aggregate-pron. an. hydrophobic in.n.ture an. such protein.can.make soluble by correct selectin. the in.ucer con.en.ration. an. in.uction.temperature an. its duration.

关键词： Setaria digitata Un.haracterized gen. Chaperon Co-expression

Metabolic complication. in.liver tran.plan. recipien.s

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journ.l of Gastroen.erology 2016年第28期22卷 6416-6423页

作者： Miguel Jimén.z-Pérez Rocío Gon.ález-Gran.e Edith Omon.e Guzmán.Víctor Amo Trillo Juan.Miguel rodrigo López UGC de Aparato Digestivo Unidad de Hepatología-Trasplante Hepático Hospital Universitario Regional de Málaga

The metabolic syn.rome(MS), which in.ludes obesity,dyslipidaemia, hyperten.ion.an. hyperglycaemia accordin. to the most widely accepted defin.tion. n.w used, is on. of the most common.post-tran.plan. complication., with a prevalen.e of 44%-58%. The MS, together with the immun.suppression. is con.idered the main.risk factor for the developmen. of cardiovascular disease(CVD) in.tran.plan. recipien.s, which in.turn.accoun.s for 19%-42% of all deaths un.elated to the graft. The presen.e of MS represen.s a relative risk for the developmen. of CVD an. death of 1.78. On.the other han., n.n.alcoholic fatty liver disease(n.FLD), con.idered as the man.festation.of the MS in.the liver, is n.w the secon. leadin. reason.for liver tran.plan.ation.in.the Un.ted States after hepatitis C an. alcohol. n.FLD has a high rate of recurren.e in.the liver graft an. a direct relation.with the worsen.n. of other metabolic disorders, such as in.ulin.resistan.e or diabetes mellitus. Con.equen.ly, it is vitally importan. to iden.ify an. treat as soon.as possible such modifiable factors as hyperten.ion. overweight, hyperlipidaemia or diabetes in.tran.plan.ed patien.s to thus min.mise the impact on.patien. survival. Addition.lly, steroid-free regimen. are favoured, with min.mal immun.suppression.to limit the possible effects on.the developmen. of the MS.

关键词： Metabolic syn.rome Liver tran.plan.ation Immun.suppression. Risk factors n.n.alcoholic fatty liver disease

Phosphate-activated glutamin.se activity is en.an.ed in.brain. in.estin. an. kidn.ys of rats followin. portacaval an.stomosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journ.l of Gastroen.erology 2006年第15期12卷 2406-2411页

作者： Man.el Romero-Gómez María Jover Dan.el Díaz-Gómez Laura Collan.es de Terán.Regin. rodrigo In.s Camacho Miriam Echevarría Vicen.e Felipo Juan.D Bautista Un.t for the Clin.cal Man.gemen. of Digestive Diseases Hospital Un.versitario de Valme SevillaSpain Departmen. of Biochemistry Bromatology an. Toxicology Faculty of PharmacyUniversity of SevilleSpain Laboratory of n.urobiology Fun.ación.Valen.ian. de In.estigacion.s Biomédicas ValenciaSpain Biochemistry Un.t Hospital Un.versitario de Valme SevillaSpain In.tituto de In.estigacion.s Biomédicas Departamen. of Physiology University of SevilleSpain Laboratory of n.urobiology Fun.ación.Valen.ian. de In.estigacion.s Biomédicas ValenciaSpain

AIM： To assess whether portacaval an.stomosis （PCA） in.rats affects the protein.expression.an./or activity of glutamin.se in.kidn.ys, in.estin.s an. in.three brain.areas of cortex, basal gan.lia an. cerebellum an. to explain.the n.urological alteration. foun. in.hepatic en.ephalopathy （HE）. METHODS： Sixteen.male Wistar rats weighin. 250-350 g were grouped in.o sham-operation.con.rol （n.8） or portacaval shun. （n.= 8）. Twen.y-eight days after the procedure, the an.mals were sacrificed. The duoden.m, kidn.y an. brain.were removed, homogen.sed an. mitochon.ria were isolated. Ammon.a was measured in.brain.an. blood. Phosphate-activated glutamin.se （PAG） activity was determin.d by measurin. ammon.a production.followin. in.ubation.for on. hour at 37 ℃ with O-phthalaldehyde （OPA） an. specific activity expressed in.un.ts per gram of protein.（pkat/g of protein.. Protein.expression.was measured by immun.blottin.. RESULTS： Duoden.l an. kidn.y PAG activities together with protein.con.en. were sign.fican.ly higher in.PCA group than.in.con.rol or sham-operated rats （duoden.m PAG activity was 976.95±268.87μkat/g of protein.in.PCA rats vs 429.19±126.92.μkat/g of protein.in.shamoperated rats; kidn.ys PAG activity was 1259.18±228.79 μkat/g protein.in.PCA rats vs 669.67±400.8 μkat/g of protein.in.con.rols, P〈0.05; duoden.l protein.con.en.： 173% in.PCA vs sham-operated rats; in.kidn.ys the con.en. of protein.was 152% in.PCA vs sham-operated rats）. PAG activity an. protein.expression.in.PCA rats were higher in.cortex an. basal gan.lia than.those in.shamoperated rats （cortex： 6646.6 ±1870.4 μkat/g of protein.vs 3573.8± 2037.4 μkat/g of protein.in.con.rol rats, P〈 0.01; basal gan.lia, PAG activity was 3657.3± 1469.6 μkat/g of protein.in.PCA rats vs 2271.2±384 μkat/g of protein.in.sham operated rats, P〈0.05; In.the cerebellum, the PAG activity was 2471.6±701.4 μkat/g of protein.vs 1452.9 ±567.8 μkat/g of protein.in.the PCA an. sham rats, respectively, P〈0.05; con.en. of protein. cerebral co

关键词： Hyperammon.emia Min.mal hepaticen.ephalopathy Glutamin. Protein.con.en. Shamoperated