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氨基水杨酸与安慰剂治疗具有免疫活性的HIV感染者慢性腹泻和非特异性结肠炎:一项双盲对照的先导性研究

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世界核心医学期刊文摘（胃肠病学分册） 2006年第5期2卷 15-16页

作者： rodrguez-Torres m. rodrguez-Orengo J.F. Ros-Bedoya C.F. 成虹 Fundación de Investigaci ón de Diego Avenida De Diego 359 Santurce 00909 Puerto Rico Dr.

Chronic diarrhea and colitis are common in patients positive for human immunodeficiency virus (HIV) under highly active antiretroviral treatment (HAART). This prospective doubleblind study explores the effect of mesalamine vs. placebo in HIV-positive patients. Thirteen HIV-infected patients with noninfectious chronic diarrhea and >250CD4+ cells/mm3 were randomized to mesalamine (2.4 g/day; n = 9) or placebo (n = 4) for 6 weeks. Colonoscopy was performed at baseline and week 6, and biopsies were obtained to calculate the Biopsy Activity Index (BAI). Diarrhea was assessed at baseline and end of treatment using the Disease Activity Index (DAI). Patients and clinicians completed Patient Global Improvement index (PGI) and Clinical Global Improvement index (CGI) at weeks 2 and 6. Comparisons at week 6 were statistically significant between mesalamine and placebo groups for BAI (P = 0.03), DAI (P = 0.007), PGI (P = 0.008), and CGI (P = 0.008). Furthermore, major improvements were documented in the mesalamine group at week 6 compared to baseline for all variables, whereas the placebo group did not have any. mesalamine was effective for treatment of chronic diarrhea and moderate nonspecific colitis in HIV patients.

关键词：非特异性结肠炎安慰剂治疗氨基水杨酸 HIV感染者慢性腹泻免疫活性双盲对照 HIV阳性患者高活性抗逆转录病毒治疗先导性

Beam steering application for W-band data links with moving targets in 5G wireless networks

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Journal of Communications and Information Networks 2017年第2期2卷 91-100页

作者： Alvaro morales Sebastian rodrguez Omar Gallardo Juan Jose Vegas Olmos Idelfonso Tafur monroy Technical University of Denmark Department of Photonics EngineeringOersteds PladsBuilding 343Kongens Lyngby 2800Denmarkl 2.Saint-Petersburg National Research University of Information TechnologiesMechanics and OpticsKronverksky prospektSaint Petersburg 197101Russian Federation

Abstract:Ubiquitous broadband Internet access is one of the major goals of the next generation of wireless ***,there are still some locations where this is diffcult to *** is the case on moving vehicles and,particularly,on *** the possible solutions to this problem,RoF(Radio-over-Fiber)architectures have been proposed as low-latency,cost-e ective *** elements are introduced to extend the RoF ***,the carrier frequency is raised into the W-band(75-110 GHz)to increase the available ***,a mechanical beam-steering solution based on a Stewart platform is adopted for the transmitter antenna to allow it to follow a moving receiver along a known path,thereby enhancing the coverage *** performance of a system transmitting a 2.5 Gbit/s non-return-to-zero signal generated by photonic up-conversion over a wireless link is evaluated in terms of real-time BER(Bit Error Rate)*** receiver is situated in di erent positions,and the orientation of the transmitter is changed *** below the forward error correction limit for 7%overhead are obtained over a range of 60 cm around a center point situated 2 m away from the transmitter.

关键词： 5G mobile communications mechanical steering millimeter-wave communications photonic up-conversion vehicular communications

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老年患者的急性下消化道出血

世界核心医学期刊文摘（胃肠病学分册） 2005年第9期1卷 10-11页

作者： Ros A. montoya m.J. rodrguez J.m. 王志宇 Avenida de la Libertad 208 Casillas 30007 Murcia Spain Dr.

Age is a risk factor in acute lower gastrointestinal hemorrhages (LGIH). The objectives here were to analyze: (1) diagnostic and therapeutic handling, (2) related morbidity and mortality, (3) the indications for surgery, and (4) the evolution of acute LGIH in patients ≥80 years. Forty-three patients ≥80 years with acute LGIH were reviewed retrospectively. In 86%(n = 37) related co-morbidities were found, in 9%(n = 4) there had been prior colorectal surgery, 19%(n = 8) were antiaggregated, and 7%(n = 3) were anticoagulated. One hundred thirty-two cases of acute LGIH in patients mergency ward 11 cases (26%) had hemodynamic instability and 8 of these were stabilized using conservative measures. In 39 cases an endoscopy was performed, allowing for an etiological diagnosis in 59%(n = 23) of cases, above all in those carried out in an urgent or semiurgent way. The arteriography permitted an etiological diagnosis in two of the four cases in which it was carried out. In seven patients (16%) urgent surgery was indicated: three were hemorrhoidectomies, three were subtotal colectomies, and one was a resection of the small intestine. The morbidity rate was 10%(n = 4) in the patients who were not treated and 14%(n = 1) in those treated, with a mortality rate of 8%(n = 3) and 14%(n = 1), respectively. The rate of relapse of bleeding after discharge from hospital was 42%(n = 18), with nine of these needing to be readmitted into hospital. In comparison with the control group, they present a different bleeding etiology (diverticulosis as opposed to the benign anal-rectal and small intestinal pathology in the younger population; P = 0.017), surgery is indicated with less frequency (9 versus 33%; P = 0.007), and there is a higher relapse rate (42 versus 26%; P = 0.045). Acute LGIH in geriatric patients relents in most cases with the use of conservative measures, although

关键词：下消化道出血结肠直肠手术手术指征小肠病变痔切除术结肠次全切除术出血率血流动力学肠切除术病因学诊断

激光冲击工艺对6061-T6铝合金侵蚀性能的影响（英文）

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Transactions of Nonferrous metals Society of China 2016年第6期26卷 1522-1530页

作者： J.IBARRA E.RODRíGUEZ O.JIméNEZ G.GómEZ-ROSAS m.FLORES J.VERDUZCO J.CHáVEZ Universidad de Guadalajara Departamento de Ingeniería de Proyectos Universidad de Guadalajara Departamento de Física Centro Universitario de Ciencias Exactas e Ingenierías

采用激光冲击工艺处理6061-T6铝合金,研究了二氧化硅砂对其侵蚀磨损性能的影响。其中冲击角为15°、30°、60°、90°,粒子速率为37和58 m/s,采用两种激光进行辐照。采用3D轮廓测量法表征了侵蚀形貌,并采用SEm研究其侵蚀机理。结果表明... 详细信息

采用激光冲击工艺处理6061-T6铝合金,研究了二氧化硅砂对其侵蚀磨损性能的影响。其中冲击角为15°、30°、60°、90°,粒子速率为37和58 m/s,采用两种激光进行辐照。采用3D轮廓测量法表征了侵蚀形貌,并采用SEm研究其侵蚀机理。结果表明,冲击角较小时,侵蚀磨损最大。侵蚀强度和侵蚀机理不受激光冲击工艺的影响,而与侵蚀的高应变速率有关。侵蚀图之间的差异是由于激光冲击工艺造成的表面粗糙度不同。最大质量损失和最大侵蚀深度分别出现在冲击角度为15°和30°时。最后,发现了明显的侵蚀机理的转移,从低角度的切割机制到90°时的凹坑形成。

关键词： 6061-T6铝合金侵蚀磨损激光冲击工艺

增殖性糖尿病视网膜病变、增殖性玻璃体视网膜病变和视网膜脱离患者玻璃体腔戊糖素的浓度比较

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世界核心医学期刊文摘(眼科学分册) 2006年第4期 43-44页

作者： Capeans Tomé C. De Rojas Silva m.V. rodrguez-Garca J. 曹绪胜 Fundación Instituto Galego de Oftalmoloxa Hospital Provincial de Conxo Rúa Ramón Baltar s/n 15706 Santiago de Compostela Spain

Background: Advanced glycosylation end products (AGEs)-are thought to play an important role in the pathophysiology of diabetes. Particularly, these products have been implicated in the pathogenesis of proliferative diabetic retinopathy. The majority of these products are formed from a vast range of precursor molecules, the variable chemical nature of which contributes to AGE heterogeneity. There is a growing population of structurally defined AGE adducts such as pyrraline, pentosidine, CmL and crossline that have been found to be elevated in diabetic tissues. In the present study, the levels of the glycoxidation product pentosidine were determined in vitreous samples obtained during vitrectomy from eyes with proliferative diabetic retinopathy (PDR), proliferative vitreoretinopathy (PVR), and retinal detachment (RD). Samples from cadaveric control eyes were also included in the study. The levels of pentosidine were compared among the groups. methods: Seventy-three vitreous samples were collected from eyes undergoing vitrectomy for PDR (n=33), PVR (n=28) and RD (n=12). Eighteen samples from cadaveric control eyes were also included in the study. A modified Bradford’s method was used to assay protein content, and vitreous levels of pentosidine were determined by high-performance liquid chromatography after acid hydrolysis and pretreatment with SP-Sephadex. Statistical analyses were performed using a two-sided mann-Whitney U test. Results: The levels of pentosidine [median (interquartile range)]were 0.92 (0.55-1.26) pmol/mg of protein in the PDR cases, 1.12 (0.46-1.80) pmol/mg of protein in PVR, and 1.02 (0.24-1.44) pmol/mg of protein in RD. In the cadaveric control eyes pentosidine levels were 0.97 (0.68-1.30) pmol/mg of protein. The pentosidine levels of the four groups did not differ significantly. Conclusions: The levels of the glycoxidation product pentosidine (expressed as pmol/mg of protein) in the vitreous of eyes with PDR do not differ significantly from those

关键词：增殖性玻璃体视网膜病变糖尿病视网膜病变视网膜脱离戊糖五碳糖单糖患者

第4级亲属的常染色体隐性白介素-1受体相关激酶-4缺乏

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世界核心医学期刊文摘（儿科学分册） 2006年第A10期2卷 31-32页

作者： Cardenes m. von Bernuth H. Garca- Saavedra A. C. rodrguez- Gallego 郭战宏 Departments of Immunology and microbiology Dr. Negrn Universitary Hospital Gran Canaria SpainDr.

We report a kindred with autosomal recessive interleukin- 1 receptor- associated kinase 4 (IRAK- 4) deficiency in 3 fourthdegree relatives. A diagnosis of IRAK- 4 deficiency should be considered in families with invasive bacterial disease, even if the individuals affected are only distantly related, which falsely suggests multigenic or dominant inheritance with low penetrance.

关键词：常染色体隐性外显率细菌感染性疾病显性遗传名第多基因遗传侵袭性

小切口白内障摘除术和超声乳化白内障吸除术的疗效比较

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世界核心医学期刊文摘(眼科学分册) 2006年第4期 54-55页

作者： Ali′o J. rodrguez-Prats J.L. Galal A. Ramzy m. 潘佳鸿 Dr. Edificio VISSUm Avda. De Denia s/n 03016 Alicante Spain

Purpose: To compare outcomes of microincision cataract surgery (mICS) with coaxial phacoemulsification. Design: Prospective randomized consecutive case series. Participants: One hundred eyes of 50 patients with nuclear or corticonuclear cataract (grades 2+to 4) with Lens Opacities Classification System III. methods: One hundred eyes (50 patients) were randomly operated through clear corneal incisions using 2 techniques: coaxial phacoemulsification (50 eyes) and microincision cataract surgery (50 eyes). main Outcome measures: mean phacoemulsification time, total phacoemulsification percent, effective phacoemulsification time (EPT) (calculated by multiplying total phacoemulsification time in seconds by the average power percent used), intraoperative total balanced salt solution (BSS) volume, visual outcome, vectorial astigmatic changes, corneal thickness, endothelial cell count, and anterior chamber flare and cells preoperatively and at 1 day, 1 month, and 3months. Results: Statistically significant differences were found between mICS and coaxial phacoemulsification regarding mean incision size, mean total phacoemulsification percent, and EPT. There were no significant differences between the techniques regarding the mean percent of endothelial cell loss, anterior chamber cell count and flare, mean phacoemulsification time, pachymetric measures or total BSS volume utilized, or visual outcome. The vectorial astigmatic changes in the mICS group showed a change of ≤0.25 diopters (D) in 35%of the eyes, 0.25 to 0.5 D in 50%of the eyes, and 0.5 to 1.0 D in 15%of the eyes. These changes were induced by the surgery. Vectorial astigmatic changes of >1 D were not observed. In the coaxial phacoemulsification group, vectorial astigmatic changes of 1.0 D. mean vectorial astigmatic changes were 0.36±0.23

关键词：超声乳化白内障吸除术小切口白内障摘除术角膜厚度

出生时的皮褶厚度:性别和人体测量参数的影响

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世界核心医学期刊文摘（儿科学分册） 2005年第10期1卷 28-28页

作者： rodrguez G. Samper m.P. Olivares J.L. 郭战宏 Depto. Pediat . Radiol. Y Med. Fis. Facultad de Medicina Universidad de Zaragoza C/Domingo Miral s/n 50009 Zaragoza Spain Prof.

Weight, length, and skinfold thicknesses were measured in 4634 term and preter m neonates. Sex and weight/length ratio were important determinants of the amoun t and distribution of the subcutaneous fat store at birth... 详细信息

关键词：皮褶厚度测量参数生时皮下脂肪可测量决定因子

窦组织细胞增生伴巨大淋巴结病:3例临床病理研究

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世界核心医学期刊文摘（儿科学分册） 2006年第12期2卷 26-26页

作者： Bernácer-Borja m. Blanco-rodrguez m. Sanchez-GranadosJ.m. A. Cazorla-Jimenez 郭战宏 Anatoma Patolágica Department Fundacián Jiménez DazAvenida Reyes Catlicos228040 MadridSpain

Introduction:We report three cases of sinus histiocytosis,a rare disease of unknown aetiology with massive lymphadenopathy(SHmL),also known as Rosai-Dorfman (RD) disease,in apaediatric population. This proliferative histiocytic disorder is defined by histological and immunohistochemical (IHC) characteristics and can manifestas nodal involvement with variable enlargement of the lymph nodes (two cases) and extranodal manifestations involving skin and larynx involvement (onecase). One patient had hypergammaglobulinemia. The morphological investigation revealed that all lymph nodes showed hyperplasia of sinuses with abundant histiocytic cell with intracytoplasmic lymphocytes. Skin and larynx biopsies showed a histiocyte and lymphocyte infiltrate with similar *** ultrastructural study was carried out on material from one patient. In the IHC study,SHmL cells expressed phagocytic markers such as CD68 and S100,but markers for Langerhan’s(CD1a) or dendritic cells (DRC,CD23 and CNA42) were *** patients had a complete remission after surgical excision and no other treatment,but the third patient was treated with radiotherapy after a relapse with obstruction of the upperairway. Conclusion:This disorder must be considered in the differential diagnosis of young patients who exhibit massive or multiple lymphadenopathi- es,especially when involvement of the cervical area occurs. Due to the good outcome of the disease,a conservative approach is justified.

关键词：窦组织细胞增生临床病理研究淋巴结病细胞标志淋巴结外组织细胞淋巴结增大形态学检查郎格