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An efficient voting based decentralized revocation protocol for vehicular ad hoc networks

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Digital Communications and Networks 2020年第4期6卷 422-432页

作者： Miraj Asghar Lei Pan robin Doss Centre for Cyber Security Research and Innovation(CSRI) Deakin UniversityGeelong3220Australia

Vehicular Ad-hoc NETworks(VANETs)enable cooperative behaviors in vehicular environments and are seen as an integral component of Intelligent Transportation Systems(ITSs).The security of VANETs is crucial for their successful deployment and widespread adoption.A critical aspect of preserving the security and privacy of VANETs is the efficient revocation of the ability of misbehaving or malicious vehicles to participate in the *** is usually achieved by revoking the validity of the digital certificates of the offending nodes and by maintaining and distributing an accurate Certificate Revocation List(CRL).The immediate revocation of misbehaving vehicles is of prime importance for the safety of other vehicles and *** this paper,we present a decentralized revocation approach based on Shamir’s secret sharing to revoke misbehaving vehicles with very low *** enhancing VANETs’security,our proposed protocol limits the size of the revocation list to the number of the revoked ***,the authentication process is more efficient,and the communication overhead is *** experimentally evaluate our protocol to demonstrate that it provides a reliable solution to the scalability,efficiency and security of VANETs.

关键词： VANETs Security Authentication Public key infrastructure Decentralized revocation

Molecular basis of inherited calcium channelopathies:role of mutations in pore-forming subunits

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Acta Pharmacologica Sinica 2006年第7期27卷 799-812页

作者： Lynn MCKEOWN Philip robin Owen T JONES Faculty of Life Sciences the University of ManchesterManchesterUK

The pore-forming alpha subunits of voltage-gated calcium channels contain theessential biophysical machinery that underlies calcium influx in response to *** combination with requisite auxiliary subunits,these pore sub-units form calcium channel complexes that are pivotal to the physiology andpharmacology of diverse cells ranging from sperm to *** surprisingly,mutations in the pore subunits generate diverse pathologies,termedchannelopathies,that range from failures in excitation-contraction coupling tonight *** the last decade,major insights into the mechanisms ofpathogenesis have been derived from animals showing spontaneous or *** parallel,there has been considerable growth in our understandingof the workings of voltage-gated ion channels from a structure-function,regula-tion and cell biology *** we document our current understandingof the mutations underlying channelopathies involving the voltage-gated calciumchannel alpha subunits in humans and other species.

关键词： calcium channels channelopathies mutation

Genotypic,size and morphological diversity of virioplankton in a deep oligomesotrophic freshwater lake(Lac Pavin,France)

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Journal of Environmental Sciences 2017年第3期29卷 48-59页

作者： Jonathan Colombet Agnès robin Télesphore Sime-Ngando Laboratory Microorganisms:Oenome and Environment Clermont University Blaise PascalUMR CNRS 602324 avenue des LandaisBP 80026F-63171 AubiereFrance CIRAD UMR Eco&Sols2 place Viala34060 Montpellier Cedex 1France

We examined changes in morphological and genomic diversities of viruses by means of transmission electronic microscopy and pulsed field gel electrophoresis （PFGE） over a nine-month period （April-December 2005） at four different depths in the oligomesotrophic Lac Pavin. We found that the majority of viruses in this lake belonged to the family of Siphouiridae or were untailed, with capsid sizes ranging from 30 to 60 nm, and exhibited genome sizes ranging from 15 to 45 kb. On average, 12 different genotypes dominated each of the PFGE fingerprints. The highest genomic viral richness was recorded in summer （mean = 14 bands per PFGE fingerprint） and in the epilimnion （mean = 13 bands per PFGE fingerprint）. Among the physico-chemical and biological variables considered, the availability of the hosts appeared to be the main factor regulating the variations in the viral diversity.

关键词： VirusLac PavinDynamicMorphological diversity Genomic diversity

Novel Antiviral Agents Targeting HIV Entry and Transmission

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Virologica Sinica 2007年第6期22卷 451-461页

作者： Qinxue Hu robin Shattock Center for Infection Department of Cellular and Molecular Medicine St George＇s University of London London SW17 ORE UK State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Wuhan 430071 China

Studies of the mechanism of HIV entry and transmission have identified multiple new targets for drug development. A range of inhibitors have demonstrated potent antiretroviral activity by interfering with CD4-gp120 interaction,coreceptor binding or viral-cell fusion in preclinical and clinical studies. One of these agents,fusion inhibitor enfuvirtide,is already in clinical use. Here we review the progress in the development of specific entry inhibitors as novel therapeutics. The potential of entry inhibitors as topical microbicides to block HIV transmission is also discussed.

关键词： HIV- 1 Entry Transmission Antiretroviral therapy Microbicide

Variability of waste copper slag concrete and its effect on the seismic safety of reinforced concrete building: A case study

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Frontiers of Structural and Civil Engineering 2022年第1期16卷 117-130页

作者： Swetapadma PANDA Nikhil P.ZADE Pradip SARKAR robin DAVIS Department of Civil Engineering Institute of Technical Education and ResearchOdisha 751030India Department of Civil Engineering National Institute of Technology RourkelaOdisha 769008India Department of Civil Engineering National Institute of Technology CalicutKerala 673601India

Proven research output on the behavior of structures made of waste copper slag concrete can improve its utilization in the construction industry and thereby help to develop a sustainable built *** numerous studies on waste copper slag concrete can be found in the published literature,no research has focused on the structural application of this type of *** particular,the variability in the strength properties of waste copper slag concrete,which is required for various structural applications,such as limit state design formulation,reliability-based structural analysis,etc.,has so far not attracted the attention of *** paper quantifies the uncertainty associated with the compressive-,flexural-and split tensile strength of hardened concrete with different dosages of waste copper slag as fine ***-fit probability distribution models are proposed based on statistical analyses of strength data generated from laboratory *** addition,the paper presents a reliability-based seismic risk assessment of a typical waste copper slag incorporated reinforced concrete framed building,considering the proposed distribution *** results show that waste copper slag can be safely used for seismic resistant structures as it results in an identical probability of failure and dispersion in the drift demand when compared with a conventional concrete building made of natural sand.

关键词： waste copper slag quantification of variability goodness-of-fit test seismic risk assessment PSDM

Construction of Multi-Substituted Benzenes via NHC-Catalyzed Reactions of Carboxylic Esters

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Chinese Journal of Chemistry 2018年第4期36卷 333-337页

作者： Jichang Wu Chengli Mou Yonggui robin Chi Laboratory Breeding Base of Green Pesticide and Agricultural Bioengi- neering Key Laboratory of Green Pesticide and Agricultural Bioengi- neering Ministry of Education Guizhou University Huaxi District Gui- yang Guizhou 550025 China School of Pharmacy Guiyang College of Traditional Chinese Medicine Huaxi District Guiyang Guizhou 550025 China

A carbene-catalyzed ester activation reaction for the synthesis of multi-substituted benzenes is developed. Tetra-substituted benzene com- pounds are efficiently synthesized through this methodology. Compared with aldehyde substrates used in previous reports, the ester substrates used here are much more readily available and inexpensive. In addition, the TEMPO oxidant used here is more inexpensive than the quinones commonly used in related carbene-catalyzed reactions.

关键词： N-heterocyclic carbene carboxylic ester benzene synthesis organocatalysis TEMPO oxidation

Genomic imbalances in esophageal carcinoma cell lines involve Wnt pathway genes

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World Journal of Gastroenterology 2011年第24期17卷 2909-2923页

作者： Jacqueline Brown Hannelie Bothma robin Veale Pascale Willem National Health Laboratory Services and University of the Witwatersrand School of Molecular and Cell Biology University of the Witwatersrand

AIM： To identify molecular markers shared across South African esophageal squamous cell carcinoma （ESCC） cell lines using o/togenetics, fluorescence in situ hybridization （FISH） and single nucleotide polymorphism （SNP） array copy number analysis. METHODS： We used conventional cytogenetics, FISH, and multicolor FISH to characterize the chromosomal rearrangements of five ESCC cell lines established in South Africa. The whole genome copy number profile was established from 250K SNP arrays, and data was analyzed with the CNAT 4.0 and GISTIC software. tions involved the following chromosomal regions and genes： 11q13.3 （CCND1, FGF3, FGF4, FGF19, MYEOV）, 8q24.21（C-MYC, FAM84B）, 11q22.1-q22.3 （B[RC2, BIRC3）, 5p15.2 （CTNND2）, 3qll.2-q12.2 （MINA） and 18p11.32 （TYMS, YES1）. The significant deletions included 1p31.2-p31.1 （CTH, GADD45a, DIRAS3）, 2q22.1 （LRPIB）, 3p12.1-p14.2 （FHIT）, 4q22.1-q32.1 （CASP6, SMAD1）, 8p23.2-q11.1 （BNIP3L） and 18q21.1-q21.2 （SMAD4, DCC）. The 3p11.2 translocation breakpoint was shared across four cell lines, supporting a role for genes involved at this site, in particular, the EPHA3 gene which has previously been reported to be deleted in ***： The finding that a significant number of genes that were amplified （FGF3, FGF4, FGF19, CCND1 and C-MYC） or deleted （SFRP2 gene） are involved in the Wnt and fibroblast growth factor signaling pathways, suggests that these pathways may be activated in these cell lines.

关键词： Esophagus Cancer Single nucleotide polymorphism arrays Fluorescent in situ hybridization

A case of phenibut withdrawal and treatment with baclofen

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World Journal of Emergency Medicine 2023年第4期14卷 338-340页

作者： Michael Morris James Espinosa Alan Lucerna robin Lahr Department of Emergency Medicine Rowan University SOM/Jefferson StratfordNJ 08084USA Emergency Medicine Residency Program Director Rowan University SOM/Jefferson StratfordNJ 08084USA

Phenibut(β-phenyl-γ-aminobutyric acid)is a psychoactive gamma-aminobutyric acid(GABA)analog marketed online as a nutritional and nootropic(cognition enhancing)*** consumption poses a high risk of potential *** from phenibut mimics benzodiazepine and alcohol withdrawal and can be dangerous.A number of approaches have been described for phenibut withdrawal,including protocols that include baclofen,but for inpatient and outpatient *** we describe a 30-year-old male who presented to an emergency department(ED)with insomnia,anxiety and palpitations after he stopped taking phenibut.

关键词： treatment withdrawal alcohol

Model Identification of a Micro Air Vehicle

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Journal of Bionic Engineering 2007年第4期4卷 227-236页

作者： Jorge Nio Flavius Mitrache Peter Cosyn robin De Keyser Department of Electrical Energy Systems and Automation Ghent University Technologiepark 913 9052 Ghent Belgium Department of Flow Heat and Combustion Mechanics Ghent University Sint-Pietersnieuwstraat 41 9000 Ghent Belgium

This paper is focused on the model identification of a Micro Air Vehicle （MAV） in straight steady flight condition. The identification is based on input-output data collected from flight tests using both frequency and time dorrtain techniques. The vehicle is an in-house 40 cm wingspan airplane. Because of the complex coupled, multivariable and nonlinear dynamics of the aircraft, linear SISO structures for both the lateral and longitudinal models around a reference state were derived. The aim of the identification is to provide models that can be used in future development of control techniques for the MAV.

关键词： Micro Air Vehicles system identification flight tests