检索结果-南通市图书馆

Photoacoustic detection of circulating melanoma cells in late stage patients

在线全文

学校读者我要写书评

暂无评论

Journal of Innovative Optical Health Sciences 2020年第6期3卷 47-54页

作者： John A.Viator Marc Hazur Andrea Sajewski Ahmad Tarhini Martin e.Sanders robert H.edgar Department of engineering Duquesne University 600 Forbes Avenue PittsburghPennsylvania 15282USA Department of Bioengineering University of Pittsburgh 3700 O'Hara Street PittsburghPA 15260USA Moffitt Comprehensive Cancer Center and Research Institute 10920 McKinley Drive TampaFlorida 33612USA Acousys Biodevices Inc 1777 Highland Drive Ann ArborMichigan 48108USA

Melanoma is the deadliest skin cancer and is responsible for over 7000 deaths in the US *** spread of cancer,or metastasis,is responsible for these deaths,as secondary tumors interrupt normal organ *** tumor cells,or those cells that spread throughout the body from the primary tumor,are thought to be responsible for *** developed an optical method,photoacoustic flow cytometry,in order to detect and enumerate circulating melanoma cells(CMCs)from blood samples of *** tested the blood of StageⅣmelanoma patients to show the ability of the photoacoustic flow cytometer to detect these rare cells in *** then tested the system on archived blood samples from StageⅢmelanoma patients with known outcomes to determine if detection of CMCs can predict future *** detected between 0 and 66 CMCs in StageⅣ*** the StageⅢstudy,we found that of those samples with CMCs,two remained disease free and five developed *** those without CMCs,six remained disease free and one developed *** believe that photoacoustic detection of CMCs provides valuable information for the prediction of metastasis and we postulate a system for more accurate prognosis.

关键词： Diagnosis metastasis optoacoustics

MRI analysis and clinical significance of lower extremity muscle cross-sectional area after spinal cord injury

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第5期12卷 714-722页

作者： robert M.Lester Kori Johnson Refka e.Khalil Rehan Khan Ashraf S.Gorgey Spinal Cord Injury and Disorders Center Hunter Holmes McGuire Veterans Administration Medical Center (VAMC) Richmond VA USA Department of Physical Medicine and Rehabilitation Virginia Commonwealth University Richmond VA USA Radiology Service Hunter Holmes McGuire Veterans Administration Medical Center (VAMC) Richmond VA USA

Shortly after spinal cord injury（SCI）, the musculoskeletal system undergoes detrimental changes in size and composition, predominantly below the level of injury. The loss of muscle size and strength, along with increased immobility, predisposes persons with SCI to rapid and severe loss in bone mineral density and other health related consequences. Previous studies have highlighted the significance of measuring thigh muscle cross-sectional area, however, measuring the size and composition of muscles of the lower leg may provide insights on how to decrease the risk of various comorbidities. The purpose of the current review was to summarize the methodological approach to manually trace and measure the muscles of the lower leg in individuals with SCI, using magnetic resonance imaging. We also intend to highlight the significance of analyzing lower leg muscle cross-sectional area and its relationship to musculoskeletal and vascular systems in persons with SCI.

关键词： spinal cord injury magnetic resonance imaging pressure ulcers venous thromboembolism cardiovascular disease bone health

ZmGns,a maize class I β-1,3-glucanase,is induced by biotic stresses and possesses strong antimicrobial activity

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Plant Biology 2015年第3期57卷 271-283页

作者： Yu-Rong Xie Yenjit Raruang Zhi-Yuan Chen robert L.Brown Thomas e.Cleveland Department of Plant Pathology and Crop Physiology Louisiana State University Agricultural Center Biotechnology Research Institute the Chinese Academy of Agricultural Sciences Southern Regional Research Center USDA-ARS

Plant b-1,3-glucanases are members of the pathogenesis-related protein 2（PR-2） family,which is one of the 17 PR protein families and plays important roles in biotic and abiotic stress *** of the differentially expressed proteins（spot 842） identified in a recent proteomic comparison between five pairs of closely related maize（Zea mays L.） lines differing in aflatoxin resistance was further investigated in the present ***,the corresponding cDNA was cloned from maize and designated as *** encodes a protein of338 amino acids containing a potential signal *** expression of Zm Gns was detectible in all tissues studied with the highest level in *** was significantly induced by biotic stresses including three bacteria and the fungus Aspergillus *** was also induced by most abiotic stresses tested and growth hormones including salicylic *** vivo,ZmGns showed a significant inhibitory activity against thebacterial pathogen Pseudomonas syringae *** DC3000 and fungal pathogen Botrytis cinerea when it overexpressed in *** high level of expression in the silk tissue and its induced expression by phytohormone treatment,as well as by bacterial and fungal infections,suggest it plays a complex role in maize growth,development,and defense.

关键词： β-1 3-Glucanase biological activity expression profiles Zea mays ZmGns

ecological correlates of invasion impact for Burmese pythons in Florida

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2012年第3期7卷 254-270页

作者： robert N.ReeD John D.WILLSON Gordon H.RODDA Michael e.DORCAS US Geological Survey Fort Collins Science CenterFort CollinsColorado Department of Fish and Wildlife Conservation Virginia TechBlacksburgVirginia Department of Biology Davidson CollegeDavidsonNorth CarolinaUSA

An invasive population of Burmese pythons(Python molurus bivittatus)is established across several thousand square kilometers of southern Florida and appears to have caused precipitous population declines among several species of native *** has this giant snake had such great success as an invasive species when many established reptiles have failed to spread?We scored the Burmese python for each of 15 literature-based attributes relative to predefined comparison groups from a diverse range of taxa and provide a review of the natural history and ecology of Burmese pythons relevant to each *** focused on attributes linked to spread and magnitude of impacts rather than establishment *** results suggest that attributes related to body size and generalism appeared to be particularly applicable to the Burmese python’s success in *** attributes with the highest scores were:high reproductive potential,low vulnerability to predation,large adult body size,large offspring size and high dietary ***,attributes of ectotherms in general and pythons in particular(including predatory mode,energetic efficiency and social interactions)might have also contributed to invasion *** establishment risk assessments are an important initial step in prevention of new establishments,evaluating species in terms of their potential for spreading widely and negatively impacting ecosystems might become part of the means by which resource managers prioritize control efforts in environments with large numbers of introduced species.

关键词： body size Burmese python Florida invasive species Python molurus

Issues in the Care and Treatment of HCV/HIV Co-Infection for Key Populations in Resource-Constrained Settings

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Health 2014年第14期6卷 1803-1815页

作者： Thomas F. Kresina robert Lubran H. Westley clark Center for Substance Abuse Treatment Substance Abuse and Mental Health Services Administration Rockville USA

Globally, the epidemic of hepatitis virus infection is increasing in the context of common viral transmission routes with the Human Immunodeficiency Virus (HIV). Thus, co-infection with both hepatitis virus and HIV is becoming a common occurrence, particularly for key populations. Studies of key populations, people who inject drugs, sex workers, transgendered individuals and men having sex with men, report high levels of illicit drug and/or alcohol use along with limited access to health care and medical treatment. Without the medical management of co-occurring substance use disorders and hepatitis C virus (HCV) infection, a significant proportion of this population with HCV/HIV co-infection will progress to chronic liver disease then subsequently end-stage liver disease. Thus, access to comprehensive care and treatment, including HCV testing with subsequent care and treatment of acute/chronic HCV infection is essential to address the global burden of disease. Increased efforts are needed globally to address the barriers to comprehensive care and treatment for key populations with HCV/HIV co-infection.

关键词： Hepatitis C Infection HIV Substance Abuse Treatment Care and Treatment Key Populations

The effects of Bio-inspired electromagnetic Fields on Normal and Cancer Cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Bionic engineering 2019年第5期16卷 943-953页

作者： Xuelei Liu Zongming Liu Zhenning Liu Shujun Zhang Kamal Bechkoum Michael clark Luquan Ren Key Laboratory of Bionic engineering(Ministry of educatiori) College of Biological and Agricultural Engineerings Jilin UniversityChangchun 130022China Department of Anesthesiology Jilin Cancer HospitalChangchun 130000China School of Computing and Technology University of GloucestershireThe ParkCheltenhamGL502RHUK Magnacare Health Groups 20-22 Pemberton Street Birmingham5186NYUK

The electromagnetic field(eMF)is one of many environmental factors,which earth creatures are exposed *** are many reports on the effects of eMF on living ***,since the mechanism has not yet been fiilly understood,the biological effects of eMF are still *** order to explore the effects of bio-inspired eMF(BIeMF)on normal and cancer cells,various cultured cells have been exposed to BIeMF of different directions,***,parallel and *** reduced ATP production in Hela and A549 cancer cells is found for the parallel and vertical *** careful examination on Hela cells has revealed a cell density dependent inhibition on colony *** morphological observation of BIeMF-exposed Hela cells has suggested that the retarded cell proli feration is probably caused by cell death via *** these results may afford new insights for cancer prevention and treatment.

关键词： electromagnetic fields(eMF) bio-inspired electromagnetic fields(BIeMF) directionality cancer cell proliferation

Biosurfactants from lactic acid bacteria:A critical review on production,extraction,structural characterization and food application

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Bioscience 2022年第2期46卷 14-23页

作者： Hippolyte T.Mouafo Alphonse T.Sokamte Augustin Mbawala robert Ndjouenkeu Somashekar Devappa Centre for Food and Nutrition Research Institute of Medical Research and Medicinal Plants’StudiesPoBox:13033Yaound´eCameroon Department of Food Processing and Quality Control University Institute of TechnologyUniversity of Ngaound´er´ePoBox:454 Ngaound´er´eCameroon Department of Food Science and Nutrition National School of Agro-Industrial SciencesUniversity of Ngaound´er´ePoBox:454 Ngaound´er´eCameroon Department of Microbiology and Fermentation Technology CSIR-Central Food Technological Research InstituteMysore570020India

Biosurfactants are structurally diverse classes of amphiphilic molecules derived from *** have various properties such as surface,emulsification,antibacterial,anti-adhesive,anti-biofilm,antioxidant activity that can be used in many industrial *** interest in these molecules compared to their synthetic counterparts is due to their biodegradability,low toxicity,structural diversity,and stability over a wide range of pH,temperature,and *** biosurfactants,those derived from lactic acid bacteria(LAB)attracted attention nowadays due to the GRAS(Generally recognized as safe)status of these *** production by LAB strains has been documented in several investigations,and they deal with the functionality and chemical nature of *** biosurfactants were mainly a complex mixture of proteinaceous compounds,glycolipids,glycoproteins,or *** are only a few studies reporting on the elucidation of the structure of LAB ***,biosurfactants’production process includes several unit operations starting from screening methods to the characterization of the biosurfactant *** review highlights the different techniques used in the screening of biosurfactants production by LAB,their extraction and purification processes,and their structural characterization and application in the food industry.

关键词： Biosurfactants Lactic acid bacteria Screening Purification Structural characterization

Docosahexaenoic acid-rich fish oil prevented insulin resistance by modulating gut microbiome and promoting colonic peptide YY expression in diet-induced obesity mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2022年第1期11卷 177-188页

作者： Wanxiu Cao Fang Liu robert WLi Yaoxian Chin Yuming Wang Changhu Xue Qingjuan Tang College of Food Science and engineering Ocean University of ChinaQingdao 266003China Key Laboratory of Marine Drugs Ministry of EducationSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China United States Department of Agriculture Agriculture Research Service(USDA-ARS)Animal Genomics and Improvement LaboratoryBeltsvilleMD 20705USA Hainan Tropical Ocean University Sanya 572022China Laboratory for Marine Drugs and Bioproducts Qingdao National Laboratory for Marine Science and TechnologyQingdao 266003China

It is unclear how docosahexaenoic acid(DHA)improves insulin resistance via modulating gut microbiome in obese *** used diet-induced obesity(DIO)mice as a model to study the effects of DHA-rich fish oil(DHA-FO)on host metabolic disorders and colonic ***-FO reduced fat deposition,regulated lipid profiles and alleviated insulin resistance in DIO *** because DHA-FO prevented the permeation of lipopolysaccharide across intestinal epithelial barrier,and promoted peptide YY(PYY)secretion via the mediation of short chain fatty acids receptor(FFAR2)in ***,DHA-FO might regulate PYY expression by reversing microbial dysbiosis,including increasing the abundance ofAkkermansia muciniphila and Lactobacillus,and suppressing the growth of ***-FO also altered gut microbial function(e.g."linoleic acid metabolism")associated with PYY expression(r>0.80,Perein,DHA-FO enhanced insulin action on glucose metabolism by altering gut microbiome and facilitating colonic PYY expression in DIO mice.

关键词： Docosahexaenoic acid Diet-induced obesity Insulin resistance Peptide YY Gut microbiome

Aircraft Brake Dust Dispersion (Airwash) Testing

在线全文

学校读者我要写书评

暂无评论

Occupational Diseases and environmental Medicine 2022年第4期10卷 255-261页

作者： Charles L. Blake robert e. Bailey Kevin M. Guth Raymond D. Harbison Apex Companies Marietta GA USA eSi Colorado Springs CO USA Center for environmental and Occupational Risk Analysis and Management College of Public Health University of South Florida Tampa FL USA

Prior industrial hygiene research involving wheel brake changing on a light general aviation aircraft has shown negligible potential for asbestos fiber exposure to mechanics that perform such work. This is despite the use of organic-style brake friction pads that contained asbestos. It has been otherwise established that chrysotile asbestos is largely degraded to a non-crystalline, amorphous substance by the heat and mechanical shear forces inherent to the braking process. However, trace (es of chrysotile have been found in brake wear dust. Disc-style brakes, the types used on aircraft, are of open design, such that wear dust is typically dispersed into the ambient air during and after brake application. For fixed-gear aircraft, the brake assemblies are also subject to substantial air velocities while the aircraft is in flight. This research was undertaken to measure and characterize the airflows experienced by aircraft wheel assemblies during takeoff, cruise, and landing maneuvers. No wear (brake) dust was observed at any point during the study.

关键词： Aircraft Brakes Asbestos Airwash