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Noninvasive ventilation in cancer children with acute respiratory failure

Journal of Acute Disease 2017年第1期6卷 23-27页

作者： Sema Yilmaz riza dincer yildizdas Oguz Dursun Bulent Karapinar Tanil Kendirli Demet Demirkol Agop Citak Alphan Kupesiz Hakan Tekguc Muhterem Duyu Pinar Yazici Ufuk Yukselmis Caglar Odek Ayhan Yaman Suleyman Bayraktar Guntuluk Fatma Betul Cakir Department of Pediatric Hematology/Oncology Faculty of MedicineYeditepe UniversityIstanbulTurkey Intensive Care Unit Department of PediatricFaculty of MedicineCukurova UniversityAdanaTurkey Intensive Care Unit Department of PediatricFaculty of MedicineAkdeniz UniversityKonyaaltiAntalyaTurkey Intensive Care Unit Department of PediatricFaculty of MedicineEge UniversityBornovaIzmirTurkey Intensive Care Unit Department of PediatricFaculty of MedicineAnkara UniversityAnkaraTurkey Intensive Care Unit Department of PediatricFaculty of MedicineBezmialem UniversityIstanbulTurkey Intensive Care Unit Department of PediatricFaculty of MedicineIstanbul UniversityIstanbulTurkey Department of Pediatric Hematology/Oncology Faculty of MedicineBezmialem UniversityIstanbulTurkey

Objective: To establish the effectiveness of noninvasive ventilation in cancer children with acute respiratory failure. Methods: The data of 33 cancer patients were obtained prospectively from six different pediatric intensive care units in Turkey between the years of 2012 and 2013. Results: The diagnosis was leukemias in 25 (75.8%), lymphomas in 3 (9.1%) and other solid tumors in 5 (15.1%) patients. Pneumonia in 12 (36.3%) and sepsis in 15 (45.4%) patients were seen as the common reasons of respiratory failure. The mean PaO2/FiO2 ratios were (164.22 ± 37.24) and (126.80 ± 42.73) in noninvasive ventilation success and failure group, respectively. Noninvasive ventilation was successful in 18 (54.5%) patients. The failure group consisted of 15 patients required intubation. A total of 14 (42.4%) patients died. The clinical outcome in terms of success and failure was meaningful statistically (P = 0.0 00 1). Conclusions: Our results could encourage the use of noninvasive ventilation in children with cancer who develop acute respiratory failure. It should be considered as a useful therapeutic approach to avoid endotracheal intubation.

关键词： Noninvasive ventilation Respiratory Children Cancer

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