Noninvasive ventilation in cancer children with acute respiratory failure

作     者：Sema Yilmaz Riza Dincer Yildizdas Oguz Dursun Bulent Karapinar Tanil Kendirli Demet Demirkol Agop Citak Alphan Kupesiz Hakan Tekguc Muhterem Duyu Pinar Yazici Ufuk Yukselmis Caglar Odek Ayhan Yaman Suleyman Bayraktar Guntuluk Fatma Betul Cakir 

作者机构：Department of Pediatric Hematology/OncologyFaculty of MedicineYeditepe UniversityIstanbulTurkey Intensive Care UnitDepartment of PediatricFaculty of MedicineCukurova UniversityAdanaTurkey Intensive Care UnitDepartment of PediatricFaculty of MedicineAkdeniz UniversityKonyaaltiAntalyaTurkey Intensive Care UnitDepartment of PediatricFaculty of MedicineEge UniversityBornovaIzmirTurkey Intensive Care UnitDepartment of PediatricFaculty of MedicineAnkara UniversityAnkaraTurkey Intensive Care UnitDepartment of PediatricFaculty of MedicineBezmialem UniversityIstanbulTurkey Intensive Care UnitDepartment of PediatricFaculty of MedicineIstanbul UniversityIstanbulTurkey Department of Pediatric Hematology/OncologyFaculty of MedicineBezmialem UniversityIstanbulTurkey 

出 版 物：《Journal of Acute Disease》 (急性病杂志（英文版）)

年 卷 期：2017年第6卷第1期

页      面：23-27页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Noninvasive ventilation Respiratory Children Cancer 

摘      要：Objective: To establish the effectiveness of noninvasive ventilation in cancer children with acute respiratory failure. Methods: The data of 33 cancer patients were obtained prospectively from six different pediatric intensive care units in Turkey between the years of 2012 and 2013. Results: The diagnosis was leukemias in 25 (75.8%), lymphomas in 3 (9.1%) and other solid tumors in 5 (15.1%) patients. Pneumonia in 12 (36.3%) and sepsis in 15 (45.4%) patients were seen as the common reasons of respiratory failure. The mean PaO2/FiO2 ratios were (164.22 ± 37.24) and (126.80 ± 42.73) in noninvasive ventilation success and failure group, respectively. Noninvasive ventilation was successful in 18 (54.5%) patients. The failure group consisted of 15 patients required intubation. A total of 14 (42.4%) patients died. The clinical outcome in terms of success and failure was meaningful statistically (P = 0.0 00 1). Conclusions: Our results could encourage the use of noninvasive ventilation in children with cancer who develop acute respiratory failure. It should be considered as a useful therapeutic approach to avoid endotracheal intubation.