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ECOLOGICAL MODEL FOR SUSTAINABLE AGRICULTURE: A HOLISTIC APPROACH TO INTEGRATED BIOTIC STRESS MANAGEMENT OF MAJOR PESTS

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ECOLOGICAL MODEL FOR SUSTAINABLE AGRICULTURE: A HOLISTIC APP...

siRNA-mediated downregulation of TC21 sensitizes esophageal cancer cells to cisplatin

The ⅩⅤth International Plant Protection Congress

作者： V.K.SEHGAL C/o R.K.pal Department of Entomology College of Agriculture G.B.Pant University of Agriculture ＆ Tech. Pantnagar - 263 145District Udham Singh Nagar Uttaranchal India Department of Entomology College of Agriculture G.B.Pant University of Agriculture ＆ Tech. Pantnagar - 263 145 District Udham Singh Nagar Uttaranchal India

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World Journal of Gastroenterology 2012年第31期18卷 4127-4135页

作者： Md.Raghibul Hasan Shyam singh Chauhan Rinu Sharma Ranju Ralhan Department of Biochemistry All India Institute of Medical SciencesNew Delhi 110029India Department of Biotechnology School of BiotechnologyGuru Gobind Singh Indraprastha UniversityNew Delhi 110075India Department of Otolaryngology-Head and Neck Surgery Joseph and Mildred Sonshine Family Centre for Head and Neck DiseasesMount Sinai HospitalTorontoON M5G 1X5Canada Department of Pathology and Laboratory Medicine Alex Simona Shnaider Laboratory for Molecular OncologyMount Sinai HospitalTorontoON M5G 1X5Canada

AIM： To determine the functional significance of TC21 in esophageal squamous cell carcinoma （ESCC）. METHODS： TC21 siRNA transfection was carried out using Hyperfectamine to knock down TC21, and tran- scripts were analyzed by reverse transcription-poly- merase chain reaction and protein by Western *** demonstrated the effect of TC21 downregulation of cell signaling in esophageal cancer cells by assess- ing the phosphorylation status of its downstream tar- gets, phosphoinositide 3-kinase （PI3K）, phosphatase and tensin homolog （PTEN）, protein kinase B （pal〈t）, nuclear factor-KB （NF-~B） and cyclinD1 using specific antibodies. Cell survival analysis after cisplatin treat- ment was carried out by cell viability assay and cell cycle analysis using flow cytometry. RESULTS： TC21 knockdown in human ESCC cell line TEl3 cells, showed only a marginal increase （14.2%） in cell death compared with control cells. The expres- sions of the signaling proteins PI3K and pAkt, transcrip- tion factor NF-KB, and cell cycle protein cyclin D1 were markedly decreased in response to TC21 downregula- tion, whereas the level of pPTEN, an antagonist of PI3K, was increased. In addition, we evaluated the potential of TC21 as a putative target for sensitizing ESCC cells to the chemotherapeutic agent cisplatin. Increased cell death （38.4%） was observed in cells treated with cis- platin after TC21 knockdown compared with cells which were treated with cisplatin alone （20% cell death）. CONCLUSION： Results suggest that TC21 mediates its effects via the PI3K-Akt pathway, NF-KB and cyclin D1, and enhances chemoresistance in esophageal cancer cells.

关键词： TC21 Esophageal squamous cell carci-noma siRNA Cisplatin Chemosensitivity

Anti-bacterial Properties of Transition Metal Complexes of Copper Metal Ion:A Mini Review

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Journal of Metallic Material Research 2022年第2期5卷 27-38页

作者： Abhay Nanda Srivastva Nisha Saxena Netra pal singh Jayant Kumar Department of Chemistry Nitishwar MahavidyalayaB.R.A.Bihar UniversityMuzarrafpur842002India University Department of Chemistry B.R.A.Bihar UniversityMuzaffarpur842001India Department of Chemistry M.R.M.CollegeL.N.Mithila UniversityDarbhanga846004India Department of Chemistry D.D.U.Gorakhpur UniversityGorakhpur273009India Graduate Student Department of ZoologyNitishwar MahavidyalayaB.R.A.Bihar UniversityMuzarrafpur842002India

Bacterial infections are a major cause for impulsive deaths in human *** infections of the respiratory,gastrointestinal and central nervous system account for the majority of cases of sudden *** available drugs are getting ineffective by each passing day as the mutation is very fast in these pathogenic microbes resulting in drug *** growing resistance of bacteria necessitates the development of new and effective compounds of desired characteristics that could bar the rapid development of bacterial cell inside of the host *** with cellular resistance for clinical antibiotics,co-bacterial infections during microbial attacks(***,fungus,protozoans etc.)also demand for some novel antibacterial drugs having high efficacy and minimal side effects on human *** antibiotics should also be compatible with remedies ongoing for core microbial ***,in demand of search for effective antibacterial moieties,the scope of transition metal complexes as drug gives a good signal against the pathogenic bacteria by inhibiting their *** action of metal complexes on bacterial cell may be due to impremiablity,enzymatic interruptions,ribosomal interactions,disturbance in the path of protein synthesis,denaturing of genetic materials *** the *** in complexes may interrupt the lipophilisity through the bacterial cell *** of metal ions in organic moieties behaving as ligand delocalizeπ-electrons upon the entire chelate ring and this chelation results in overlapping of ligand orbital and partial sharing of(+)ve charge of metal ion with donor *** structural modifications in metal and organic lone pair donor species are the supposed reasons for their enhanced antimicrobial activities against pathogenic *** present review focuses on the impact of recently synthesized,well characterized mono and binuclear transition metal complexes of Cu ions that have the potential to be the drug of th

关键词： Ligands Coordination compounds Antimicrobial activity Drug resistance

Conductivity Studies in Proton Irradiated AgI-Ag2O-V2O5-TeO2 Super-Ionic Glass System

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Artefacts in cone beam CT

Materials Sciences and Applications（材料科学与应用期刊） 2010年第2期

作者： Poonam Sharma Dinesh Kumar Kanchan Meenakshi Pant Karan pal singh

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Open Journal of Stomatology 2013年第5期3卷 292-297页

作者： Prashant P. Jaju Mayuri Jain Ajita singh Akanksha Gupta rishi Raj College of Dental Sciences and Research Centre Bhopal India

Cone beam computed tomography (CBCT) is the modern third dimension applied in the field of oral maxillofacial region. With lower radiation dose compared to conventional CT, its applications in dentistry has increased tremendously. Artefacts can seriously degrade the quality of computed tomographic (CBCT) images, sometimes to the point of making them diagnostically unusable. To optimize image quality, it is necessary to understand why artifacts occur and how they can be prevented or suppressed. CT artifacts originate from a range of sources;physical based, scanner based and patient based. This article highlights the causes of artefacts on CBCT images and methods to avoid them.

关键词： CBCT Artefacts Metal Artefacts

Ivabradine—The Final Crusader for Postoperative Junctional Ectopic Tachycardia,a Case Report with Literature Review

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Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic

World Journal of Cardiovascular Surgery（心血管外科国际期刊） 2019年第8期

作者： Manoj Kumar Sahu Harsha Vardhan Niraghatam Nikhil Bansal Sarvesh pal singh palleti Rajashekar Shiv Kumar Choudhary

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Stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor Pedro Lylyk Omer F Eker Laura Mechtouff Michel Piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby John Emma Griffin John Thornton Jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei Pascal Jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk Pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes Pereira Patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin Pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-Jehani Sunil A Sheth Victor S Lopez Rivera James E Siegler Achmad Fidaus Sani Ajit S Puri Anna Luisa Kuhn Gianmarco Bernava Paolo Machi Daniel G Abud Octavio M Pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh P Mehta Naoto Kimura Mamoru Murakami Jin Soo Lee Ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong Juan F Arenillas Mario Martinez-Galdamez Jordi Blasco Alejandro Rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon John Alex Brehm Marios Psychogios William J Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic Jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa Peeling Yuichi Murayama Hugh Stephen Winters Johnny Wong Mohamed Teleb Jeremy Payne Hiroki Fukuda Kosuke Miyake Junsuke Shimbo Yusuke Sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA Radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt Radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance Stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of Radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,*** 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,p<0.0001).Embolisation of ruptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative *** analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,p<0.0001).A relative increase in ruptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this *** There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 *** findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid

Fungal diversity notes 1151-1276:taxonomic and phylogenetic contributions on genera and species of fungal taxa

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Fungal Diversity 2020年第1期100卷 5-277页

作者： Kevin DHyde Yang Dong Rungtiwa Phookamsak Rajesh Jeewon DJayarama Bhat EBGareth Jones Ning‑Guo Liu Pranami DAbeywickrama Ausana Mapook Deping Wei Rekhani HPerera Ishara SManawasinghe Dhandevi Pem Digvijayini Bundhun Anuruddha Karunarathna Anusha HEkanayaka Dan‑Feng Bao Junfu Li Milan CSamarakoon Napalai Chaiwan Chuan‑Gen Lin Kunthida Phutthacharoen Sheng‑Nan Zhang Indunil CSenanayake Ishani DGoonasekara Kasun MThambugala Chayanard Phukhamsakda Danushka STennakoon Hong‑Bo Jiang Jing Yang Ming Zeng Naruemon Huanraluek Jian‑Kui(Jack)Liu Subodini NWijesinghe Qing Tian Saowaluck Tibpromma Rashika SBrahmanage Saranyaphat Boonmee Shi‑Ke Huang Vinodhini Thiyagaraja Yong‑Zhong Lu Ruvishika SJayawardena Wei Dong Er‑Fu Yang Sanjay Ksingh Shiv Mohan singh Shiwali Rana Sneha SLad Garima Anand Bandarupalli Devadatha MNiranjan VVenkateswara Sarma Kare Liimatainen 馻‑ Tuula Niskanen Andy Overall Renato Lúcio Mendes Alvarenga Tatiana Baptista Gibertoni Walter PPfliegler EnikőHorváth Alexandra Imre Amanda Lucia Alves Ana Carla da Silva Santos Patricia Vieira Tiago Timur SBulgakov Dhanushaka NWanasinghe Ali HBahkali Mingkwan Doilom Abdallah MElgorban Sajeewa SNMaharachchikumbura Kunhiraman CRajeshkumar Danny Haelewaters Peter EMortimer Qi Zhao Saisamorn Lumyong Jianchu Xu Jun Sheng Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina State Key Laboratory for Conservation and Utilization of Bio‑Resources in Yunnan Yunnan Agricultural UniversityKunming 650201China Yunnan Research Institute for Local Plateau Agriculture and Industry Kunming 650201China Key Laboratory for Agro‑biodiversity and Pest Control of Ministry of Education Yunnan Agricultural UniversityKunming 650201China Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand East and Central Asia Regional Office World Agroforestry Centre(ICRAF)Kunming 650201YunnanChina Centre for Mountain Futures(CMF) Kunming Institute of BotanyKunming 650201YunnanChina Mushroom Research Foundation 128 M.3 Ban Pa Deng T.Pa PaeA.Mae TaengChiang Mai 50150Thailand Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius No.128/1‑J Azad Co‑Op Housing SocietyCurcaGoa Velha 403108India Department of Entomology and Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Department of Botany and Microbiology College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Kingdom of Saudi Arabia School of Science Mae Fah Luang UniversityChiang Rai 57100Thailand Faculty of Agriculture National Resources and EnvironmentNaresuan UniversityPhitsanulok 65000Thailand Beijing Key Laboratory of Environment Friendly Management on Fruit Diseases and Pests in North China Institute of Plant and Environment ProtectionBeijing Academy of Agriculture and Forestry SciencesBeijing 100097China Department of Soil Ecology UFZ-Helmholtz Centre for Environmental ResearchHalleGermany Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Shenzhen Key Laboratory of Microbial Genetic Engineering College of Life Sciences and OceanographyShenzhen UniversityShenzhen 518060China Department of Plant M

Fungal diversity notes is one of the important journal series of fungal taxonomy that provide detailed descriptions and illustrations of new fungal taxa,as well as providing new information of fungal taxa *** article is the 11th contribution to the fungal diversity notes series,in which 126 taxa distributed in two phyla,six classes,24 orders and 55 families are described and *** in this study were mainly collected from Italy by Erio Camporesi and also collected from China,India and Thailand,as well as in some other European,North American and South American *** described in the present study include two new families,12 new genera,82 new species,five new combinations and 25 new records on new hosts and new geographical distributions as well as sexual-asexual *** two new families are Eriomycetaceae(Dothideomycetes,family incertae sedis)and Fasciatisporaceae(Xylariales,Sordariomycetes).The twelve new genera comprise Bhagirathimyces(Phaeosphaeriaceae),Camporesiomyces(Tubeufiaceae),Eriocamporesia(Cryphonectriaceae),Eriomyces(Eriomycetaceae),Neomonodictys(Pleurotheciaceae),Paraloratospora(Phaeosphaeriaceae),Paramonodictys(Parabambusicolaceae),Pseudoconlarium(Diaporthomycetidae,genus incertae sedis),Pseudomurilentithecium(Lentitheciaceae),Setoapiospora(Muyocopronaceae),Srinivasanomyces(Vibrisseaceae)and Xenoanthostomella(Xylariales,genera incertae sedis).The 82 new species comprise Acremonium chiangraiense,Adustochaete nivea,Angustimassarina camporesii,Bhagirathimyces himalayensis,Brunneoclavispora camporesii,Camarosporidiella camporesii,Camporesiomyces mali,Camposporium appendiculatum,Camposporium multiseptatum,Camposporium septatum,Canalisporium aquaticium,Clonostachys eriocamporesiana,Clonostachys eriocamporesii,Colletotrichum hederiicola,Coniochaeta vineae,Conioscypha verrucosa,Cortinarius ainsworthii,Cortinarius aurae,Cortinarius britannicus,Cortinarius heatherae,Cortinarius scoticus,Cortinarius subsaniosus,Cytospora fusispor

关键词： 96 new taxa Agaricomycetes Ascomycota Basidiomycota Dothideomycetes Lecanoromycetes Leotiomycetes Pezizomycetes Phylogeny Saccharomycetes Taxonomy