Anti-bacterial Properties of Transition Metal Complexes of Copper Metal Ion:A Mini Review
作者机构：Department of ChemistryNitishwar MahavidyalayaB.R.A.Bihar UniversityMuzarrafpur842002India University Department of ChemistryB.R.A.Bihar UniversityMuzaffarpur842001India Department of ChemistryM.R.M.CollegeL.N.Mithila UniversityDarbhanga846004India Department of ChemistryD.D.U.Gorakhpur UniversityGorakhpur273009India Graduate StudentDepartment of ZoologyNitishwar MahavidyalayaB.R.A.Bihar UniversityMuzarrafpur842002India
出 版 物：《Journal of Metallic Material Research》 (金属材料研究（英文）)
年 卷 期：2022年第5卷第2期
页 面：27-38页
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
主 题：Ligands Coordination compounds Antimicrobial activity Drug resistance
摘 要：Bacterial infections are a major cause for impulsive deaths in human *** infections of the respiratory,gastrointestinal and central nervous system account for the majority of cases of sudden *** available drugs are getting ineffective by each passing day as the mutation is very fast in these pathogenic microbes resulting in drug *** growing resistance of bacteria necessitates the development of new and effective compounds of desired characteristics that could bar the rapid development of bacterial cell inside of the host *** with cellular resistance for clinical antibiotics,co-bacterial infections during microbial attacks(***,fungus,protozoans etc.)also demand for some novel antibacterial drugs having high efficacy and minimal side effects on human *** antibiotics should also be compatible with remedies ongoing for core microbial ***,in demand of search for effective antibacterial moieties,the scope of transition metal complexes as drug gives a good signal against the pathogenic bacteria by inhibiting their *** action of metal complexes on bacterial cell may be due to impremiablity,enzymatic interruptions,ribosomal interactions,disturbance in the path of protein synthesis,denaturing of genetic materials *** the *** in complexes may interrupt the lipophilisity through the bacterial cell *** of metal ions in organic moieties behaving as ligand delocalizeπ-electrons upon the entire chelate ring and this chelation results in overlapping of ligand orbital and partial sharing of(+)ve charge of metal ion with donor *** structural modifications in metal and organic lone pair donor species are the supposed reasons for their enhanced antimicrobial activities against pathogenic *** present review focuses on the impact of recently synthesized,well characterized mono and binuclear transition metal complexes of Cu ions that have the potential to be the drug of th
维普期刊数据库