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Effect of Pulsed Ultraviolet Light on the Total Phenol Content of Elderberry (<i>Sambucus nigra</i>) Fruit

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Food and Nutrition Sciences 2012年第6期3卷 774-783页

作者： Ramesh Murugesan Valérie Orsat Mark Lefsrud Department of Bioresource Engineering Faculty of Agricultural and Environmental Sciences Macdonald Campus McGill University Québec Canada.

The changes in total polyphenolics in elderberry (Sambucus nigra) following treatment with various doses of pulsed ultraviolet rays (UV) were investigated. Four pulsed UV durations (5, 10, 20, 30 seconds) at three energy dosages (4500, 6000, 11,000 J/m2/pulse) were considered for the research. All treated elderberry fruits were incubated for 24 h at room temperature (25℃) following treatment to ensure enough response duration for enhanced development of polyphenols by the berries. The highest increase in total phenolics around 50% was found with 11,000 J/m2/pulse for a 10 seconds treatment while nearly 40% increase in total phenolics was found at an energy dosage of 11,000 J/m2/pulse after 5 seconds exposure. Even though most of the treatments indicated an increase in total polyphenols, some treatment expressed a decrease in phenolics content when compared to untreated fruits.

关键词： Elderberry Antioxidant Polyphenols Pulsed Ultraviolet Light Abiotic

Family empowerment and quality of life of parents raising children with Developmental Disabilities in 78 Japanese families

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International Journal of Nursing Sciences 2017年第1期4卷 38-45页

作者： rie Wakimizu Keiko Yamaguchi Hiroshi Fujioka Department of Child Health Care Nursing Division of Health Innovation and NursingFaculty of MedicineUniversity of Tsukuba1-1-1 TennodaiTsukuba CityIbaraki 305-8575Japan Department of Nursing Science Doctor's Program Graduate School of Comprehensive Human SciencesUniversity of Tsukuba1-1-1 TennodaiTsukuba CityIbaraki 305-8575Japan Department of Nursing Tsukuba International University6-8-33 ManabeTsuchiura CityIbaraki 300-0051Japan

Objectives: The families of these children experience distress both at the time of diagnosis and afterward.A top priority is to understand family empowerment,family function,and family members' quality of life (QoL) and to effectively support these families in *** objective of this study was to assess the actual conditions of families living with children having DDs and to explore the factors associated with family empowerment and parents' ***: We surveyed ninety-three parents (78 mothers,15 fathers) from 78 families which lived with children with DDs in the capital region of *** assessed two main outcomes using the Japanese versions of the following instruments: Family Empowerment Scale (FES),World Health Organization Quality of Life 26 (WHOQOL26),and other six *** and multiple regression analyses were ***: No medication,cooperation with child rearing,assistance from a developmental support center,solved problems related to child rearing,and higher scores in Problem Solving contributed to higher FES *** WHOQOL26 scores were related to being a full-time housewife,higher self-esteem,no developmental support,a broad emotional support network,higher scores in Problem Solving and Role Function,and lower scores in Affective Reaction and General ***: We revealed that family empowerment and QoL of parents rearing children with DDs in Japan were affected by various subscales of family function and other family *** interventions for improving family empowerment and QoL should be researched in the future.

关键词： Developmental disabilities Family empowerment Japan Multiple regression analysis Quality of life Social support

Adult case of an omphalomesenteric cyst resected by laparoscopic-assisted surgery

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World Journal of Gastroenterology 2006年第5期12卷 825-827页

作者： Fumi Sawada rie Yoshimura Kenichi Ito Kazuhiko Nakamura Hajime Nawata Kazuhiro Mizumoto Shuji Shimizu Takahiro Inoue Takashi Yao Masazumi Tsuneyoshi Atushi Kondo Naohiko Harada Department of Medicine and Bioregulatory Science Department of Surgery and Oncology Department of Anatomic Pathology Graduate School of Medical SciencesKyushu UniversityFukuoka 812-8582FukuokaJapan Department of Gastroenterology Aso Iizuka HospitalIizuka 820-8505FukuokaJapan Department of Gastroenterology Fukuoka Higashi Medical CenterKoga 811-3195FukuokaJapan

This report describes an extremely rare adult case of an omphalomesenteric cyst resected by laparoscopicassisted surgery. A 29-years-old Japanese man was referred and admitted to Kyushu University Hospital because of an abdominal mass and an elevated serum CEA （carcinoembryonic antigen） level （21.3 ng/mL） in August 2001. Abdominal CT and US demonstrated a cystic mass with septum and calcification. Laparoscopy showed a large mass to be attached to his abdominal wall, measuring 110 mm × 70 mm× 50 mm and filled with mucus. The mass was resected by laparoscopicassisted surgery. The histological findings of its wall showed fibromuscular tissue, adipose tissue, calcification, and an intestinal structure. It was finally diagnosed to be an omphalomesenteric cyst.

关键词： Omphalomesenteric cyst Laparoscopicassisted surgery

Marine Species Introduced on the French Channel-Atlantic Coasts: A Review of Main Biological Invasions and Impacts

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Open Journal of Ecology 2015年第5期5卷 227-257页

作者： Valérie Stiger-Pouvreau Gérard Thouzeau UBO-CNRS Institut Universitaire Européen de la Mer UMR 6539 (LEMAR) Plouzané France

The impacts of anthropogenisation modify permanently the distribution patterns of brackish and marine species. Globalization leads to a rapid increase of the numbers of introduced species anywhere in the world. Biological invasions often result in significant losses in the economic value, biological diversity and function of invaded ecosystems. This review presents the main pathways of introduction of non-indigenous species and the main benthic taxonomic groups being established and/or invasive along the French Channel-Atlantic coasts. A focus is put on main invasive marine species in the intertidal and subtidal zones of Brittany (France), among macroalgae (Sargassum muticum, Grateloupia turuturu, Undaria pinnatifida, Codium fragile and Gracilaria vermiculophylla), halophytes (Spartina alterniflora) and benthic invertebrates (Mollusks: Crepidula fornicata, Crassostrea gigas and Venerupis philippinarum). The species biology, introduction vectors, reproductive and dispersal capacities are considered, together with proliferation patterns along the Channel-Atlantic coasts. The ecological impacts of these species on the environment are also described, as well as the European regulations existing to limit alien species introduction and some examples of struggle against the invaders including eradication trials and biomass valorization. Last, the on-going impacts of global changes on alien species invasiveness along the Channel-Atlantic coasts are discussed.

关键词： Invasive Species French Channel-Atlantic Coasts Halophyte Macroalgae Mollusks Impacts Remediation

Study on the production of IL-12, IL-10 in early stage after infection with Babesia microti and Babesia rodhaini in mice

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Journal of Northeast Agricultural University(English Edition) 2007年第1期14卷 17-21页

作者： LIU Yun Hachikuchi rie Kenichiro Ono College of Veterinary Medicine Northeast Agricultural University Harbin 150030 China Department of Clinical Pathobiology Veterinary Medical Science Graduate School of Agricultural Life Science University of Tokyo Tokyo 113 Japan

The serum levels of IL-12 and IL-10 in mice after infected with Babesia microti （B. microti） and Babesia rodhaini （B. rodhaini） were examined. Collected the mice serum and examined the concentration of IL-12 and IL-10 by using ELISA after infection with B. microti and B. rodhaini at 0, 3, 6, 9, 12, 18, 24, 36, 72, 96 h in mice. The results showed that B. microti infection resulted in IL-12 increasing, which peaked at 3 and 24 h after the infection, while same infection did not induce a significant change in IL-10 compared to uninfected mice. When mice were infected with B. rodhaini, any significant changes were not decteted both in IL-12 and IL-10 in comparison with uninfected animals during the period of 3-72 h after infection. Instead, a significant decline in IL-12 and IL-10 was found compared to uninfected mice 96 h after infection with B. rodhaini. It indicates that the mutagenetic cytokine is IL-12 in the serum of mice after infection with B. microti, and no any significant changes were detected in both IL-12 and IL-10 from 0 to 72 h after infected with B. rodhaini.

关键词： B. microti B. rodhaini mice IL-12 IL-10

Mesorif Gabbros(External Rif, North Morocco): Ophiolitic Suture Witness or a “Newly Discovered” Manifestation of the Central Atlantic Magmatic Province?

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Acta Geologica Sinica(English Edition) 2020年第S1期94卷 11-12页

作者： Faouziya HAISSEN Oriol GIMENO-Vives Geoffroy MOHN Valérie BOSSE Mohamed Najib ZAGHLOUL Achraf ATOUABAT Dominique FRIZON DE LAMOTTE UniversitéHassan II de Casablanca Facultédes Sciences Ben MsikDépartement de GéologieB.P.5366MaarifCasablancaMorocco UniversitéCergy-Pontoise Département Géosciences et Environnement 5GEG1 rue Descartes950000 Neuville/Oise CedexFrance UniversitéBlaise Pascal Laboratoire Magmas et Volcans(UMR 6524)CNRS5 rue Kessler63038Clermont-FerrandFrance UniversitéAbdelmalek Essaadi Facultédes Sciences et Techniques de TangerBP 41990000 TangerMorocco

The Rif Mountain located in Northern Morocco represents the westernmost extremity of the Peri-Mediterranean Alpine orogenic *** belt is classically subdivided into:1)Internal zones(or Internal Rif which is an allochthonous metamorphic domain known worldwide thanks to the presence of large peridotite outcrops);2)flysch zones(sediments corresponding to the original cover of the Maghrebian Tethys);and 3)External zones(or External Rif representing the North African margin remnants).The External Rif is itself subdivided into Prerif,Mesorif and Intrarif domains from the South to the North and is composed by Upper Triassic to Cenozoic sediments structured in a nappe *** rock intrusions were reported in this External Rif since the preliminary geological studies even if they were wrongly mapped as"granites".Later careful fieldwork and mapping studies specified nevertheless their gabbroic nature.A more recent petrological and geochemical study of a few outcrops of those gabbroic intrusions conducted the corresponding authors,encouraged by the presence of ultramafic rocks(Beni Malek serpentines)in the eastern part of the External Rif to consider those gabbros as oceanic and so,associated to"an ophiolitic suture".Nevertheless,a recent and extended survey on the architecture and the rifting history of the Mesozoic margin of the Maghrebian Tethys focusing mainly on the Mesorif domain favor another *** detailed petrography of those mafic intrusions(mainly gabbros+dolerites and rarely extrusive rocks);their geochemical fingerprints and mainly their geochronological data(ages around 200 Ma based on U-Pb zircon LA-ICP dating)all together indicate clearly that those mafic intrusions are rather a"newly discovered"manifestation of the Central Atlantic Magmatic Province activity"CAMP"in the External Rif *** CAMP magmatism has been largely well described and characterized in all the other geological domains of Morocco(Anti-Atlas,High Atlas,Middle Atlas

关键词： external Rif Mesorif gabbro ophiolitic suture CAMP(the Central Atlantic Magmatic Province)

Several factors including ITPA polymorphism influence ribavirin-induced anemia in chronic hepatitis C

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World Journal of Gastroenterology 2012年第41期18卷 5879-5888页

作者： Akihito Tsubota Noritomo Shimada Hiroshi Abe Kai Yoshizawa rie Agata Yoko Yumoto Makiko Ika Yoshihisa Namiki Keisuke Nagatsuma Hiroshi Matsudaira Kiyotaka Fujise Norio Tada Yoshio Aizawa Institute of Clinical Medicine and Research The Jikei University School of Medicine163-1 Kashiwa-shitaKashiwaChiba 277-8567Japan Division of Gastroenterology and Hepatology Kashiwa HospitalThe Jikei University School of Medicine163-1 Kashiwa-shitaKashiwaChiba 277-8567Japan Department of Gastroenterology Shinmatsudo Central General Hospital1-380 ShinmatsudoMatsudoChiba 270-0034Japan Division of Gastroenterology and Hepatology Katsushika Medical CenterThe Jikei University School of Medicine6-41-2 AotoKatsushika-kuTokyo 125-8506Japan

AIM： To construct formulae for predicting the likelihood of ribavirin-induced anemia in pegylated interferon plus ribavirin for chronic hepatitis C. METHODS： Five hundred and sixty-one Japanese patients with hepatitis C virus genotype lb who had received combination treatment were enrolled and as- signed randomly to the derivation and confirmatory groups. Single nucleotide polymorphisms at or nearby ITPA were genotyped by real-time detection poly- merase chain reaction. Factors influencing significant anemia （hemoglobin concentration 〈 10.0 g/dL at week 4 of treatment） and significant hemoglobin decline （declining concentrations 〉 3.0 g/dL at week 4） were analyzed using multiple regression analyses. Prediction formulae were constructed by significantly independent factors. RESULTS： Multivariate analysis for the derivation group identified four independent factors associated with significant hemoglobin decline： hemoglobin decline at week 2 [P = 3.29× 10^4, odds ratio （OR） = 7.54 （g/dL）], estimated glomerular filtration rate [P = 2.16× 10^4, OR = 0.962 （ml/min/1.73 m2）], rs1127354 （P = 5.75 × 10^4, OR = 10.94） and baseline hemoglobin [P = 7.86 × 10^4, OR = 1.50 （g/alL）]. Using the model constructed by these factors, positive and negative predictive values and predictive accuracy were 79.8%, 88.8% and 86.2%, respectively. For the confirmatory group, they were 83.3%, 91.0% and 88.3%. These factors were closely correlated with significant anemia. However, the model could not be constructed, because no patients with rs1127354 minor genotype CA/AA had significant anemia. CONCLUSION： Reliable formulae for predicting the likelihood of ribavirin-induced anemia were constructed. Such modeling may be useful in developing individual tailoring and optimization of ribavirin dosage.

关键词： Chronic hepatitis C virus infection Ribavi-rin Pegylated interferon Prediction model Hemolyticanemia Single nucleotide polymorphism

Development of a Training Textbook for Countermeasures to “Verbal Abuse, Physical Assault, and Harassment in Pediatric Medical Settings”

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Health 2022年第1期14卷 63-69页

作者： rie Wakimizu Hinako Kuwahara Yumiko Saito Makoto Saito Department of Child Health and Developmental Nursing Faculty of Medicine University of Tsukuba Ibaraki Japan Department of Nursing Toranomon Hospital Tokyo Japan Doctoral Program in Nursing Science Graduate School of Comprehensive Human Sciences University of Tsukuba Ibaraki Japan Department of Child Health Faculty of Medicine University of Tsukuba Ibaraki Japan

Background: Recently, abuse, assault, and harassment in pediatric medical settings have become more serious. We extracted typical problems from a nationwide simultaneous survey on abuse in the pediatric medical field and developed a training textbook to simulate or discuss these issues with colleagues. This study aimed to confirm the validity and usability of the contents of this training textbook. Methods: The textbook was mailed to the heads of 51 medical institutions affiliated with the Society of Ambulatory and General Pediatrics of Japan (SAGPJ) and the participants of the SAGPJ online workshop, who were asked to evaluate the textbook using a three-point scale to answer the following questions and provide opinions and impressions about the textbook. Q1. Do you think the whole content and structure of this textbook are useful? Q2. Would you use this textbook as a training textbook for all staff at your facility? A simple tabulation was performed on the evaluation using a three-point scale, while content analysis was performed on the opinions and impressions of the participants. Results: In response to Q1 and Q2, all 63 staff members from 55 facilities answered “3: Yes.” Opinions and impressions on the training textbook included “I think it can be used for workplace training” and “it is useful for exchanging various opinions among staff members and gaining a common opinion.” Conclusion: We developed a training textbook on abuse, assault, and harassment in pediatric medical settings based on a nationwide survey and confirmed the validity and usability of its contents.

关键词： Pediatric Safety Management Textbook Validation Study Workplace Violence

Comparison of the Bacterial Microbiota in a Bale of Collected Cardboard Determined by 454 Pyrosequencing and Clone Library

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Advances in Microbiology 2014年第12期4卷 754-760页

作者： Valérie Lalande Simon Barnabé Jean-Charles Coté Département de Biologie Médicale Université du Québec à Trois-RivièresTrois-RivièresCanada Agriculture and Agri-Food Canada Research and Development CentreSaint-Jean-sur-RichelieuCanada Département de Chimie Biochimie et PhysiqueUniversité du Québec à Trois-RivièresTrois-RivièresCanada

Biofouling, the accumulation of microorganisms, is a major problem in paper mills processing paper and cardboard. This leads to the production of lower quality recycled products. Several studies have focused on the microbial content in the paper mill and the final products. Our aim was to determine the microbial biota in a bale of collected cardboard prior to entering the paper mill. Total genomic DNA was isolated and analyzed using two different methods for comparison purposes: 454 pyrosequencing and clone library. A total of 3268 V6-V8 454 pyrosequencing reads and 322 cloned V6-V8 16S rRNA nucleotide sequences were obtained. Both methods showed the presence of three major bacterial genera: Bacillus, Solibacillus and Paenibacillus, all members of the spore-forming phylum Firmicutes. Pyrosequencing, however, revealed a richer and more diverse bacterial community than clone library. It showed the presence of additional minor Firmicute genera and of a small number of Proteobacteria. The sorting at the recycling plant, the storing, and the processing at the paper mill, the end uses, will all contribute to the bacterial microbiota present in a bale of collected cardboard as revealed here.

关键词： 454 Pyrosequencing Bacterial Microbiota Cardboard Clone Library Paper Mill