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Effect of Runner Solidity on Performance of Elbow Draft Tube

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Effect of Runner Solidity on Performance of Elbow Draft Tube

Antileishmanial potential of a marine sponge Haliclona oculata against experimental visceral leishmaniasis

2011 2nd International Conference on Advances in Energy Engineering(ICAEE)

作者： Ruchi khare Vishnu Prasad Sushil Kumar Mittal Department of Civil Engineering M.A.National Institute of Technology

The significant amount of kinetic energy comes out of runner in reaction turbines and the draft tube is used to recover this kinetic energy into useful pressure *** energy recovery in draft tube depends on its design and magnitude of velocity components at runner *** the amount of kinetic energy coming out of runner depends on the solidity of runner as well as its rotational *** draft tube is important component of turbine next to *** this paper,3D viscous turbulent flow simulation has been done in the complete flow passage of Francis turbine using commercial Computational Fluid Dynamics（CFD） code for three runner solidities at different rotational *** draft tube performance parameters in non-dimensional form are computed from simulation results and the effects of runner solidity and operating speed on draft tube performance are *** simulation results are also compared with the experimental results for validation and are found to be within reasonable accuracy.

关键词： Draft tube solidity Francis turbine efficiency computational fluid dynamics

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Journal of Coastal Life Medicine 2015年第3期 187-192页

作者： Vijai Lakshmi Prashant khare Pragya Misra Mahendra Nath Srivastava Anuradha Dube Divisions of Medicinal&Process Chemistry CSIR-Central Drug Research InstituteLucknow-226001India Divisions of Parasitology CSIR-Central Drug Research InstituteLucknow-226001India Divisions of Botany CSIR-Central Drug Research Institute Lucknow-226001India

Objective:To evaluate the antileishmanial activity of a marine spongeHaliclona ***:The crude methanol extract was prepared from the freshly collected sponge and its three fractions were also prepared by maceration *** antileishmanial activity of these extract and fractions was tested againstLeishmania ***:The antileishmanial activity was tested bothin vitroand in *** crude methanol extract exerted almost complete inhibition of promastigotes(81.0%±6.9%)and 78.8%±5.2%inhibition of intracellular amastigotes at 100μg/mL with IC_(50)values of 29.5μg/mL and 40.6μg/mL,*** treatment of 500 mg/kg(p.o.)of the crude methanol extract for 5 d for Leishmania donovani infected hamsters resulted in 78.35%±10.20%inhibition of intracellular *** a lower dose(250 mg/kg),it exhibited poor *** the fractions,highestin vitro(>75%)and in vivo(84.3%±10.2%)antileishmanial activity was observed in n-chloroform fraction with IC_(50)values of 54.2μg/mL and 61μg/mL against promastigotes and intracellular amastigotes,*** fraction andn-butanol(both insoluble and soluble)fractions were found inactivein vitroand in ***:Our findings indicate that this marine sponge has the potential to provide new insight toward development of an effective antileishmanial agent and,hence,more exhaustive studies are needed for exploiting the vast marine resources of the world to combat the scourge of several parasitic diseases.

关键词： Antileishmanial activity In vitroand in vivo Marine sponge Haliclona oculata Leishmania donovani

Approach for Multiword Expression Identification in Natural Language Processing

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Computer Technology and Application 2011年第8期2卷 663-666页

作者： Deepak Sharma Prakash R. Devale Akhil K. khare Department of lnformation Technology and Bharati Vidyapeeth College of Engineering ＆ Research Pune 411043 India

In this paper, the authors are presenting the approach to extract the multiword expression （MWEs） from monolingual corpora. It both validates and generates multiword candidates. The multiword expression provides a list of candidates which are extracted and filtered according to the number of criteria and a set of standard statistical association measures. The generation of the multiword candidates is based on the surface forms, while the validation consists of series of criteria for removing noise using language independent association measures. For generating corpus count, it provides both a corpus indexation facility. Also, this approach allows easy integration with a machine learning tool for thecreation and application of supervised multiword extraction models if annotated data is available. The authors present the use of multiword in a standard configuration, for extracting MWEs from a corpus of general purpose English.

关键词： Multiword candidates association measures surface forms monolingual corpora.

Natural Products Potential and Scope for Modern Cancer Research

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American Journal of Plant Sciences 2013年第6期4卷 1270-1277页

作者： Rajeev Nema Sarita khare Parul Jain Alka Pradhan Abhishek Gupta Dharmendra Singh Center for Microbiology & Bio-Technology Research and Training Institute Bhopal Bhopal India Government of Motilal Vigyan Mahavidyalaya Bhopal India. S.V. Polytechnic College Bhopal India Sarojini Naidu Government Girls Post Graduate (Autonomous) College Bhopal India Sarojini Naidu Government Girls Post Graduate (Autonomous) College Bhopal India

In the present time Natural products are considered to be symbols of protection in comparison to the synthetic product that are regarded as unsafe to human life and environment. Although a large number of synthetic drugs are being added to the world of present pharmacopoeia, but still no system of medicine in the world has been able to solve all the health problems, which include diseases like Cancer. Therefore the search for innovative therapeutic constituents from plants is genuine and urgent. In India, there is an ocean of knowledge about medicinal plants and rich medicinal flora, but still only a few pearls have been searched as therapeutic agents. There are large numbers of original plants left which have not been investigated thoroughly from modern scientific view or their healing values have not been known. Thus there is an insistent need for systematic phytochemical examination of those plants which have not been investigated scientifically. More research can be done to investigate the unknown and unexplored potential of plants. Further analysis of plants (active compounds) can be carried out by way of making use of different analytical methods such as HPTLC, HPLC, NMR and UV spectrophotometer analysis or computer based drug designing.

关键词： Medicinal Plant Natural Product Cancer Biology

Pharmacognostic Evaluation and Antioxidant Activity of <i>Urtica dioica</i>L.

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Chinese Medicine 2012年第3期3卷 128-135页

作者： Vertika khare Pradeep Kushwaha Shikhar Verma Abhishek Gupta Sharad Srivastava AKS Rawat Pharmacognosy & Ethnopharmacology Division CSIR-National Botanical Research Institute Lucknow India

Background: Urtica dioica L. is a common Himalayan species which produces allergenic substances causing oedema and inflammation in humans. It has become a source of folk medicine for the treatment of many diseases. The leaves and roots both are used internally as a blood purifier and diuretic and an infusion of the plant is used for nasal and menstrual haemorrhage, diabetes, rheumatism, eczema, anaemia, hair loss, as an expectorant and antidiarrhoeal. Present study includes pharmacognostic evaluation, antioxidant activity and HPTLC analysis of Urtica dioica L. Methods: Pharmacognostic evaluation of aerial part of U. dioica has been performed as per Indian pharmacopoeia. In-vitro antioxidant evaluation of U. dioica has been performed using DPPH free radical scavenging activity. Ferulic acid, a potential phenolic antioxidant present in this species, has been studied through HPTLC. Results: U. dioica hydro-alcoholic extract shows positive results for antioxidant activity with IC50 value of 88.33 ± 2.88 μg/ml. Standard ascorbic acid showed IC50 value of 2.8 ± 0.62 μg/ml. Ferulic acid was identified at Rf 0.61 ± 0.01 and quantified to 0.73% in this species through CAMAG HPTLC analysis. Conclusion: The pharmacognostical parameters reported can be considered as quality standards of U. dioica in herbal industry. Hydro-alcoholic extract of U. dioica showed positive in vitro antioxidant activity. Presence of phenolic compound suggests that antioxidant activity may be due to ferulic acid content.

关键词： Antioxidant Activity DPPH Ferulic Acid HPTLC U. Dioica

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2021年混合云科技将如何发展?

软件和集成电路 2021年第3期 35-37页

作者： Mukesh khare IBM系统研究院

混合云技术的突破性发展,将成为企业挣脱禁锢、大胆采用混合云平台战略而获得可持续成长的有力保证。很少有企业能预料到2020年出现的巨大变化。2020年出现的新冠肺炎疫情打乱了整个世界的节奏,迫使企业迅速调整其技术基础设施,让员工... 详细信息

混合云技术的突破性发展,将成为企业挣脱禁锢、大胆采用混合云平台战略而获得可持续成长的有力保证。很少有企业能预料到2020年出现的巨大变化。2020年出现的新冠肺炎疫情打乱了整个世界的节奏,迫使企业迅速调整其技术基础设施,让员工能远程开展工作的同时做好更长远的规划,以应对前所未有的不确定性。对很多企业而言,重新改造IT基础设施是其生存下去的关键。

关键词：平台战略技术基础设施可持续成长混合云 IT基础设施不确定性突破性发展有力保证

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云代理软件:让企业云数据管理如虎添翼

网络安全和信息化 2019年第7期 29-30页

作者： Pratyush khare

磁带存储还有很多其他的"先天不足",例如,效率和可靠性低,且需要大量人力;空气湿度高这种看似无害的环境都可能导致磁带损坏。此外,从一大堆磁带中找出所需的磁带也是一项艰难的任务,以及在磁带上查找数据非常困难。设想一下,你愿意将... 详细信息

磁带存储还有很多其他的"先天不足",例如,效率和可靠性低,且需要大量人力;空气湿度高这种看似无害的环境都可能导致磁带损坏。此外,从一大堆磁带中找出所需的磁带也是一项艰难的任务,以及在磁带上查找数据非常困难。设想一下,你愿意将歌曲存储在录音磁带、MP3设备上,还是通过在线播放器聆听音乐?几乎没有人会选择录音磁带,尽管它的价格可能最便宜。对于企业而言也是同理。企业从磁带转向基于磁盘的解决方案或云存储备份

关键词：录音磁带播放器备份数据云数据管理

Spectroscopic, Kinetic Studies of Polyaniline-Flyash Composite

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Advances in Chemical Engineering and Science 2011年第2期1卷 37-44页

作者： Raju Khan Puja khare Bimala Prasad Baruah Ajit Kumar Hazarika Nibaran Chandra Dey 不详

Polyaniline-fly ash (PANI-FA) composites were prepared by oxidative polymerization of aniline with fly ash in presence of ammonium persulphate (APS). The PANI-FA composites were prepared with different concentrations of fly ash to aniline ratio. The composites, so prepared, were characterized by UV-vis spectroscopy, Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and thermogravimetric analysis (TGA). The thermal stability was studied by TGA and total weight loss of PANI, FA and PANI-FA composites having FA composition of 0.02%, 0.1%, 0.5% and 1.0% were found to be 82%, 39.%, 67% 65%, 62% and 61%, respectively. The UV-vis spectroscopy of the PANI-FA polymeric composite shows absorption maxima at 315 and 350 nm (due to π-π* transition of the benzenoid rings), and 578-712 nm (due to charge transfer excitations of the quinoid structure), which are characteristic of emeraldine base. FTIR spectra of the PANI-FA composite is similar to that of pure polyaniline (PANI) but with the bands for C=N, C=C and C-N shifted to lower wave numbers, i.e., 1585, 1494, 1327 and 1113 cm?1 due to strong interaction of Fe2O3 and PANI matrix. SEM shows the complexation of metal oxide with emaraldine base of PANI, significantly changing the aggregate state of polymeric molecular chain.

关键词： Polyaniline Fly-Ash TGA UV-Vis Spectroscopy FT-IR Kinetic Study and SEM

GISAID’s Role in Pandemic Response

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China CDC weekly 2021年第49期3卷 1049-1051页

作者： Shruti khare Céline Gurry Lucas Freitas Mark B Schultz Gunter Bach Amadou Diallo Nancy Akite Joses Ho Raphael TC Lee Winston Yeo GISAID Core Curation Team Sebastian Maurer-Stroh GISAID Global Data Science Initiative(GISAID) MunichGermany Bioinformatics Institute Agency for Science Technology and ResearchSingapore Oswaldo Cruz Foundation(FIOCRUZ) Rio de JaneiroBrazil Institut Pasteur de Dakar DakarSenegal National Institutes of Biotechnology Malaysia SelangorMalaysia Smorodintsev Research Institute of Influenza St.PetersburgRussia Genome Institute of Singapore Agency for Science Technology and ResearchSingapore China National GeneBank ShenzhenChina A*STAR Infectious Disease Labs(ID Labs) Singapore National Public Health Laboratory National Centre for Infectious DiseasesMinistry of HealthSingapore Department of Biological Sciences National University of SingaporeSingapore.

GISAID is a global data science initiative and the primary source of genomic and associated metadata of all influenza viruses,Respiratory Syncytial Virus(RSV)and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the pandemic coronavirus causing coronavirus disease 2019(COVID-19).GISAID’s publicly accessible data sharing platform enables collaboration of over 42,000 participating researchers from 198 nations and data generators from over 3,500 institutions across the *** the first wholegenome sequences were made available by China CDC through GISAID on January 10.

关键词： acute respiratory AID