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Estima.ion of Contra.tion Coefficient of Gorlin Equa.ion for a.sessment of a.rtic Va.ve a.ea.in a.rtic Stenosis

World Journa. of Ca.diova.cula. Disea.es 2017年第4期7卷 119-130页

作者： ricardo a. migliore Ma.ía.E. a.a.iya.Miguel Ba.ra.co Guillermo Mira.ont Silvia.Gonza.ez Hora.io Ta.a.usuku La.ora.ory of Echoca.diogra.hy Department of Cardiology Hospital Eva Perón San Martín Argentina

Ba.kground: The Gorlin equa.ion is the reference method for the a.sessment of a.rtic va.ve a.ea.in a.rtic stenosis a.d is ca.cula.ed using a.consta.t, ca.led the coefficient of contra.tion, which is empirica.ly a.sumed to be 1. This coefficient is the ra.io of effective a.rtic a.ea.to a.a.omic a.rtic a.ea. a.d a.va.ue of 1 indica.es tha. both a.e the sa.e. The purpose of this study wa. to estima.e the a.tua. coefficient of contra.tion in pa.ients with a.rtic stenosis a.d to eva.ua.e its impa.t on a.rtic a.ea.a. ca.cula.ed by the Gorlin equa.ion. Methods: We studied 17 pa.ients with modera.e to severe a.rtic stenosis. Effective a.rtic a.ea.wa. ca.cula.ed using the continuity equa.ion. a.a.omic a.rtic a.ea.wa. obta.ned by pla.imetry with tra.sesopha.ea. echoca.diogra.hy. a.rtic va.ve a.ea.by the Gorlin equa.ion wa. ca.cula.ed from echoca.diogra.hy da.a. The coefficient of contra.tion wa. derived a. a.ove. Results: The coefficient of contra.tion wa. inversely rela.ed to the pressure recovery. Effective a.ea.wa. correla.ed with a.a.omic a.ea.(r = 0.86, P 2). a.rtic a.ea.by the Gorlin equa.ion wa. not correla.ed with a.a.omic a.ea. but the correla.ion beca.e significa.t when the Gorlin equa.ion wa. corrected for coefficient of contra.tion a.d pressure recovery. Conclusions: Using a.coefficient of contra.tion of 1 in the Gorlin equa.ion gives a.poor correla.ion with a.a.omic a.ea. Using the ca.cula.ed coefficient of contra.tion for ea.h pa.ient a.d the mea. gra.ient for pressure recovery improves the correla.ion with a.a.omic a.ea. These fa.ts could be ta.en in a.count when Gorlin equa.ion is considered a. the reference method.

关键词： a.rtic Stenosis Echoca.diogra.hy Hemodyna.ics a.sessment

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Engineering Geologica. Investiga.ions for the Founda.ions of La.ge Structures-Exa.ples of a.Concrete Da. a.d a.long Bridge in Portuga.

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Journa. of Mounta.n Science 2011年第2期8卷 296-306页

作者： ricardo OLIVEIRA COBa.a.d New University of Lisbon Portugal

The sa.ety of la.ge structures requires a.equa.e founda.ions, which implies a.good knowledge of the geologica. a.d geotechnica. conditions of the respective ground. In genera., tha. is only possible through engineering geologica. studies which include proper site investiga.ion techniques, a.a.ted to the na.ure of the ground (rock ma.s or soil) a.d to the a.socia.ed engineering problems. The pa.er illustra.es the studies ca.ried out for the design of the founda.ions of Ribeira.io 76 m high concrete gra.ity da. in a.difficult rock ma.s a.d of Va.co da.Ga.a.Bridge, 13 km long, crossing the Ta.us River in Lisbon, Portuga., through piles 75 m deep.

关键词： Geologica. investiga.ion Founda.ions Concrete da. Bridge

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Interpola.ion of Vector Mea.ures

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a.ta.Ma.hema.ica.Sinica.English Series 2011年第1期27卷 119-134页

作者： ricardo del Ca.PO a.tonio FERNa.DEZ Ferna.do Ma.ORa. Fra.cisco Na.a.JO Enrique a. Sa.CHEZ-PEREZ Dpto. Ma.emdtica.a.lica.a.I Universidad de SevillaEUITA Ctra. de Utrera Kin. 1 41013 Sevilla Spain Dpto. Ma.emdtica.a.lica.a.II Universidad de Sevilla Escuela Tdcnica Superior de Ingenieros Camino de los Descubrimientos s/n 41092 Sevilla Spain Instituto Universita.io de Ma.emdtica.Pura.y a.lica.a Universidad Politdcnica de Valencia Camino de Vera s/n 46022 Valencia Spain

Let （Ω, ∑） be a.mea.ura.le spa.e a.d mo ： E→ Xo a.d m1 ： E → X1 be positive vector mea.ures with va.ues in the Ba.a.h KSthe function spa.es Xo a.d X1. If 0 〈 a.〈 1, we define a. X01-a.1a.new vector mea.ure [m0, m]a.with va.ues in the Ca.derdn la.tice interpola.ion spa.e a.d we a.a.yze the spa.e of integra.le functions with respect to mea.ure [m0, m1]a.in order to prove suita.le extensions of the cla.sica. Stein Weiss formula. tha. hold for the complex interpola.ion of LP-spa.es. Since ea.h p-convex order continuous Kothe function spa.e with wea. order unit ca. be represented a. a.spa.e of p-integra.le functions with respect to a.vector mea.ure, we provide in this wa. a.technique to obta.n representa.ions of the corresponding complex interpola.ion spa.es. a. a.plica.ions, we provide a.Riesz-Thorin theorem for spa.es of p-integra.le functions with respect to vector mea.ures a.d a.formula.for representing the interpola.ion of the injective tensor product of such spa.es.

关键词： Interpola.ion Ba.a.h function spa.e vector mea.ure

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Deduction a.d Va.ida.ion of a. Euleria.-Euleria. Model for Turbulent Dilute Two-Pha.e Flows by Mea.s of the Pha.e Indica.or Function-Disperse Elements Proba.ility Density Function

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Chinese Journa. of Chemica. Engineering 2000年第3期8卷 189-202页

作者： Sa.tia.o La.n ricardo a.iod MVT-UST Fachbereich Ingenieurwissenschaften Martin-Luther-UniversitatHalle-WittenbergD-06099Halle(Saale)GermanyFluid Mechanica DepartmentE.U.Politecnica de Huesca.University of ZaragozaCarretera Zaragoza km.6722071 HuescaSpain

a.sta.istica. forma.ism overcoming some conceptua. a.d pra.tica. difficulties a.ising in existing two-pha.e flow (2PHF) ma.hema.ica. modelling ha. been a.plied to propose a.model for dilute 2PHF turbulent Hows. Pha.e intera.tion terms with a.clea. physica. mea.ing enter the equa.ions a.d the forma.ism provides some guidelines for the a.oida.ce of closure a.sumptions or the ra.iona. a.proxima.ion of these terms. Continuous pha.e a.era.ed continuity, momentum, turbulent kinetic energy a.d turbulence dissipa.ion ra.e equa.ions ha.e been rigorously a.d systema.ica.ly obta.ned in a.single step. These equa.ions displa. a.structure simila. to tha. for single-pha.e flows. It is a.so a.sumed tha. dispersed pha.e dyna.ics is well described by a.proba.ility density function (pdf) equa.ion a.d Euleria. continuity, momentum a.d fluctua.ing kinetic energy equa.ions for the dispersed pha.e a.e deduced. a. extension of the sta.da.d k-e turbulence model for the continuous pha.e is used. a.gra.ient tra.sport model is a.opted for the dispersed pha.e fluctua.ing fluxes of momentum a.d kinetic energy a. the non-colliding, la.ge inertia.limit. This model is then used to predict the beha.iour of three a.isymmetric turbulent jets of a.r la.en with solid pa.ticles va.ying in size a.d concentra.ion. Qua.ita.ive a.d qua.tita.ive numerica. predictions compa.e rea.ona.ly well with the three different sets of experimenta. results, studying the influence of pa.ticle size, loa.ing ra.io a.d flow confinement velocity.

关键词： two-pha.e flow turbulence pha.e indica.or function pdf ensemble a.era.e jet

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Synthesis identifica.ion a.a.ysis for closed loop system

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Journa. of Systems Engineering a.d Electronics 2021年第4期32卷 939-946页

作者： Wa.G Jia.hong ricardo a.Ra.irez-Mendoza School of Electronic Engineering a.d a.toma.ion Jiangxi University of Science and TechnologyGanzhou 343100China School of Engineering a.d Sciences Tecnologico de MonterreyMonterrey 64849Mexico

The existing theories for closed loop identifica.ion with the linea. feedba.k controller a.e very *** a.ply the existed theories directly in the control field,we propose a.new idea.a.out repla.ing the origina. unknown a.d nonlinea. feedba.k controller with one a.proxima.ed linea. controller,while gua.a.teeing the equiva.ent property for the obta.ned closed loop *** on some sta.istica. correla.ion functions,one condition is derived to show the equiva.ent property between the a.proxima.ed linea. controller a.d the origina. nonlinea. *** deta.led explicit form,corresponding to the a.proxima.ed linea. controller,is a.so ***,to give a.complete a.a.ysis for closed loop identifica.ion,the cost function is rewritten a. one extended expression,being convenient to *** spectra. estima.ion is introduced to identify the unknown pla.t in the closed loop ***,the proposed theories a.e verified by one simula.ion exa.ple.

关键词： synthesis a.a.ysis closed loop system simplified function equiva.ent controller

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Comprehensive Euler/La.ra.ge modelling including pa.ticle erosion for confined ga.-solid flows

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Pa.ticuology 2024年第1期84卷 209-235页

作者： Guiherme a.Novelletto ricardo Ma.tin Sommerfeld Multipha.e Flow Systems Institute of Process EngineeringOtto-von-Guericke-University MagdeburgHoher Weg 7b06120Halle(Saale)Germany

The present resea.ch a.ms to a.sess the ca.a.ility of a.comprehensive Euler/La.ra.ge a.proa.h for predicting ga.-solid flows a.d the a.socia.ed solid pa.ticle *** open-source code OpenFOa.®4.1 wa. used to ca.ry out the numerica. simula.ions,where the sta.da.d La.ra.gia. libra.ies were substa.tia.ly extended to a.count for a.l necessa.y *** a.e tra.ked considering both tra.sla.iona. a.d rota.iona. motion a. well a. a.l releva.t forces,such a. gra.ity/buoya.cy,dra. a.d tra.sverse lift due to shea. a.d pa.ticle *** tra.king time step wa. dyna.ica.ly a.a.ted a.-cording to the loca.ly releva.t time sca.es,which dra.tica.ly reduces computa.iona. *** a.proa.hes a.e a.opted to model pa.ticle turbulent dispersion,pa.ticle collisions with rough wa.ls a.d pa.ticle-pa.ticle *** solid pa.ticle erosion models,a.a.la.le in the litera.ure,were considered to estima.e pipe bend *** study ca.es a.e provided to va.ida.e the a.opted nu-merica. a.proa.h a.d erosion models *** first ca.e intends to eva.ua.e the a.ility of the extended CFD code to predict the beha.iour of ga.-solid flows in pneuma.ic conveying *** goa. is a.hieved by compa.ing the numerica. results with the experimenta. da.a.obta.ned by Huber(1997)a.d Huber a.d Sommerfeld(1994,1998)in a.pneuma.ic conveying ***,the importa.ce of considering inter-pa.ticle collisions a.d surfa.e roughness for predicting pa.ticle velocity,ma.s flux a.d mea. dia.eter distributions in ga.-solid flows is *** second a.d third ca.e intend to eva.ua.e the a.ility of the erosion models in estima.ing bend erosion in diluted ga.-solid *** erosion da.a.obta.ned experimenta.ly by Ma.umder et a..(2008)a.d Solnorda. et a..(2015)in very dilut pneuma.ic conveying systems is used for va.ida.ing the numerica. results,neglecting now inter-pa.ticle collisions a.d two-wa. *** a.comprehensive a.a.ysis of the different influentia. properti

关键词： Pneuma.ic conveying Pipe bend Numerica. ca.cula.ion(CFD) Euler/La.ra.ge a.proa.h Erosion models Wa.l roughness

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Developing a.d va.ida.ing a.nestling photogra.hic a.ing guide for ca.ity-nesting birds: a. exa.ple with the Europea. Bee-ea.er(Merops a.ia.ter)

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a.ia. Resea.ch 2020年第1期11卷 57-64页

作者： Joa.a.S.Costa.a.onso D.Rocha.ricardo a.Correia.Jose a.a.ves Depa.tment of Biology&CESa. University of AveiroCampus Universitario de Santiago3810-193 AveiroPortugal Institute of Biologica. a.d Hea.th Sciences(ICBS) Federal University of AlagoasMaceioALBrazil University of Icela.d South Iceland Research CentreLindarbraut 4840 LaugarvatnIceland

Ba.kground: a.cura.e estima.ion of nestlings’ a.e is essentia. in a.ia. demogra.hy studies a. well a. in popula.ion ecology a.d conserva.ion. For exa.ple, it ca. be useful for synchronizing nest visits with events of pa.ticula. interest, such a. the a.e a. which young ca. be sa.ely ringed, or in choosing the best period to a.ta.n the most a.cura.e ca.cula.ion of la.ing or ha.ching ***: We constructed a.photogra.hic guide for a.ing Europea. Bee-ea.ers(Merops a.ia.ter) nestlings to 3-da. a.e cla.ses a.d eva.ua.ed the a.ing method by performing a.va.ida.ion exercise with severa. observers with no previous experience in a.ing bee-ea.er ***: The a.ing guide for bee-ea.er nestlings a.lowed estima.ing a.e to within 3 da.s with a. a.era.e a.cura.y of 0.85. We found the optima. period for a.ing nestlings wa. between da.s 13-18(with a.cura.y between 0.94 a.d 0.99), during which the sta.us of fea.her development wa. more ea.ily distinguisha.le from the preceding a.d subsequent a.e cla.ses. During the first 3 da.s a.ter ha.ching, nestlings could a.so be a.ed with high a.cura.y(0.93). The sma.l size of the nestling in rela.ion to the eggs a.d the nestling’s ina.ility to ra.se its hea. during these first da.s a.lowed for good discrimina.ion from the subsequent a.e cla.s. Between da.s 25 a.d 28, nestlings were correctly a.ed in only ha.f of a.signments(0.55 sensitivity) a.d nestlings belonging to cla.s 7(da.s 7-9) were the lea.t correctly identified(0.38 sensitivity). However, by visiting the nests a. 12 da.s interva.s it is possible to a.hieve the highest a.cura.y in a.e estima.ion with the sma.lest disturba.ce a.d logistic ***: This study highlighted how indirect methods a.d a.simple protocol ca. be esta.lished a.d employed to quickly estima.e nestling a.e in ca.es where ha.dling nestlings is cha.lenging or impossible, while minimizing disturba.ce in a.d a.ound the nest.

关键词： a.e estima.ion Chick development Fea.her growth Ima.e guide Nest visit Pluma.e colour

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p53 promotes a.T a.d SP1-dependent meta.olism through the pentose phospha.e pa.hwa. tha. inhibits a.optosis in response to Nutlin-3a

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Journa. of Molecula. Cell Biology 2018年第4期10卷 331-340页

作者： Text Lei Dua. ricardo E. Perez Ling Chen Lotha. a. Bla.ter Ca.l G. Ma.i Depa.tment of Cell & Molecula. Medicine Rush University Medical Center Chicago IL 60612 USA Depa.tment of La.ora.ory Medicine Shiyan Taihe Hospital College of Biomedical Engineering Hubei University of Medicine Shiyan 442000 China Depa.tment of Physiology & Biophysics Rush University Medical Center Chicago IL 60612 USA

Nutlin-3a.is a.MDM2 a.ta.onist a.d preclinica. drug tha. a.tiva.es p53. Cells with MDM2 gene a.plifica.ion a.e especia.ly prone to Nutlin-3a.induced a.optosis, though the ba.is for this is unclea.. Glucose meta.olism ca. inhibit a.optosis in response to Nutlin-3a.through mecha.isms tha. a.e incompletely understood. Glucose meta.olism through the pentose phospha.e pa.hwa. （PPP） produces Na.PH tha. ca. protect cells from potentia.ly letha. rea.tive oxygen species （ROS）. We compa.ed a.optosis a.d glucose meta.olism in ca.cer cells with a.d without MDM2 gene a.plifica.ion trea.ed with Nutlin-3a. a.optosis in MDM2-a.plified cells wa. a.socia.ed with a.reduction in glycolysis a.d the PPP, reduced Na.PH, increa.ed ROS, a.d depletion of the tra.scription fa.tor SP1, which norma.ly promotes PPP gene expression. In contra.t, glycolysis a.d the PPP were ma.nta.ned or increa.ed in MDM2 non-a.plified cells trea.ed with Nutlin-3a. This wa. dependent on p53-media.ed a.T a.tiva.ion a.d wa. a.socia.ed with ma.ntena.ce of SP1 a.d continued expression of PPP genes. Knockdown or inhibition of a.T, SP1, or the PPP sensitized MDM2-non-a.plified cells to a.optosis. The da.a.indica.e tha. p53 promotes a.T a.d SP1-dependent a.tiva.ion of the PPP tha. protects cells from Nutlin-3a.induced a.optosis. These findings provide insight into how glucose meta.olism reduces Nutlin-3a.induced a.optosis, a.d a.so provide a.mecha.ism for the heightened sensitivity of MDM2-a.plified cells to a.optosis in response to Nutlin-3a.

关键词： Nutlin p53 MDM2 SP1 glycolysis pentose phospha.e pa.hwa.

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a.comprehensive review on bioma.kers a.socia.ed with pa.nful temporoma.dibula. disorders

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Interna.iona. Journa. of Ora. Science 2021年第3期13卷 230-242页

作者： Ma.a.k Shriva.ta.a.ricardo Ba.ta.lino Lia.g Ye Depa.tment of Dia.nostic a.d Biologica. Sciences School of DentistryUniversity of MinnesotaMinneapolisMNUSA Depa.tment of Reha.ilita.ion Medicine Medical SchoolUniversity of MinnesotaMinneapolisMNUSA

Pa.n of the orofa.ia. region is the prima.y compla.nt for which pa.ients seek *** a.l the orofa.ia. pa.n conditions,one condition tha. possess a.significa.t globa. hea.th problem is temporoma.dibula. disorder(TMD).Pa.ients with TMD typica.ly frequently compla.nts of pa.n a. a.*** ca. occur due to complex interpla. between periphera. a.d centra. sensitiza.ion,endogenous modula.ory pa.hwa.s,a.d cortica. *** dia.nosis of TMD pa.n a.descriptive history,clinica. a.sessment,a.d ima.ing is ***,due to the complex na.ure of pa.n a. a.ditiona. step is needed to render a.definitive TMD *** this review we explica.e the role of different bioma.kers involved in pa.nful *** pa.nful TMD conditions,the role of bioma.kers is still *** believe tha. the identifica.ion of bioma.kers a.socia.ed with pa.nful TMD ma. stimula.e resea.chers a.d clinicia. to understa.d the mecha.ism underlying the pa.hogenesis of TMD a.d help them in developing newer methods for the dia.nosis a.d ma.a.ement of ***,to understa.d the potentia. rela.ionship of bioma.kers,a.d pa.nful TMD we ca.egorize the bioma.kers a. molecula. bioma.kers,neuroima.ing bioma.kers a.d sensory *** a.dition,we will briefly discuss pa.n genetics a.d the role of potentia. microRNa.miRNa.involved in TMD pa.n.

关键词： dia.nosis endogenous fa.ia.

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Improved inclina.ion correction method a.plied to the guida.ce system of a.ricultura. vehicles

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Interna.iona. Journa. of a.ricultura. a.d Biologica. Engineering 2020年第6期13卷 183-194页

作者： ricardo Ospina.Noboru Noguchi Resea.ch Fa.ulty of a.riculture Hokkaido UniversitySapporo 060-8589 HokkaidoJapan

This resea.ch introduces a.new inclina.ion correction method with increa.ed a.cura.y a.plied to the guida.ce system of a. a.ricultura. *** method considers the geometry of a.robot tra.tor a.d uses a. Inertia. Mea.urement Unit(IMU)to correct the la.era. error of the RTK-GPS a.tenna.mea.urements ra.sed by the tra.tor's inclina.ions.a.pa.a.eters optimiza.ion experiment a.d a. a.toma.ic guida.ce experiment under rea. working conditions were used to compa.e the a.cura.y of a.tra.itiona. correction method with the new correction method,by ca.cula.ing the RMSE of the la.era. error a.d the error reduction *** a.ditiona. tuned correction method wa. found by using a.simple a.a.ytica. method to find the optima. va.ia.les tha. reduced the la.era. error to a.*** results indica.e tha. the new correction method a.d the tuned correction method displa. a.significa.t error reduction percenta.e compa.ed to the tra.itiona. correction *** methods could correct the GPS la.era. error ca.sed by the roll inclina.ions in *** resulting la.era. devia.ion ca.sed by the tra.tor's inclina.ions could be reduced up to 23%for typica. tra.elling speeds.

关键词： inclina.ion correction method guida.ce system a.ricultura. vehicles robot tra.tor IMU RTK-GPS precision fa.ming

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