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Introduction of invasive mosquito species into Europe and prospects for arbovirus transmission and vector control in an era of globalization

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Infectious Diseases of Poverty 2023年第6期12卷 109-109页

作者： renke lühken Norbert Brattig Norbert Becker Bernhard Nocht Institute for Tropical Medicine Hamburg Germany Institute for Dipterology Speyer Germany Institute for Organismal Studies (COS) University of Heidelberg Heidelberg Germany

Background Mosquito research in Europe has a long history,primarily focused on malaria *** recent years,invasive mosquito species like the Asian tiger mosquito(Aedes albopictus)and the spread of arboviruses like dengue virus,chikungunya virus or bluetongue virus have led to an intensifcation of research and monitoring in *** risk of further dissemination of exotic species and mosquito-borne pathogens is expected to increase with ongoing globalization,human mobility,transport geography,and climate *** have conducted various studies to understand the ecology,biology,and efective control strategies of mosquitoes and associated *** body Three invasive mosquito species are established in Europe:Asian tiger mosquito(Aedes albopictus),Japanese bush mosquito(***),and Korean bush mosquito(Aedes koreicus).*** is the most invasive species and has been established in Europe since *** the past two decades,there has been an increasing number of outbreaks of infections by mosquito-borne viruses in particular chikungunya virus,dengue virus or Zika virus in Europe primary driven by *** the same time,climate change with rising temperatures results in increasing threat of invasive mosquito-borne viruses,in particular Usutu virus and West Nile virus transmitted by native Culex mosquito *** mosquito control programs require a high level of community participation,going along with comprehensive information campaigns,to ensure source reduction and successful *** strategies for container breeding mosquitoes like *** or Culex species involve community participation,door-to-door control activities in private *** measures can involve integration of sterile insect techniques,applying indigenous copepods,Wolbachia ***,or genetically modifed mosquitoes,which is very unlike to be practiced as standard method in the near *** Climate change and globaliza

关键词： Invasive mosquito Spread Outbreak Mosquito-borne virus Asian tiger mosquito Arbovirus Control strategy Globalization Europe

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Surveillance of arthropod-borne viruses in Benin,West Africa 2020–2021:detection of dengue virus 3 in Aedes aegypti(Diptera:Culicidae)

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Military Medical Research 2023年第5期10卷 730-732页

作者： Carine Tchibozo Gildas Hounkanrin Anges Yadouleton Alexandra Bialonski Eric Agboli renke luhken Jonas Schmidt‑Chanasit Hanna Jost laboratory of Viral Haemorrhagic Fevers and Arboviruses of Benin 01BP 918CotonouBenin Centre de Recherche Entomologique de Cotonou 01BP 918CotonouBenin Ecole Normale Supérieure de Natitingou National Universityof ScienceTechnologyEngineering and MathematicsAbomeyBenin Bernhard Nocht Institute for Tropical Medicine WHO Collaborating Centrefor Arbovirus and Haemorrhagic Fever Reference and Research20359 Ham‑burgGermany University of Health and Allied Sciences PMB 31HoGhana Faculty of Mathematics Informatics and Natural SciencesUniversitat Hamburg22609 HamburgGermany

Dear Editor,Dengue virus(DENV,family Flaviviridae,genus Flavivirus)serotypes 1 to 4(DENV-1,-2,-3,and-4)are responsible for more than 100 million infections per year *** of DENV infection can be diverse,reaching from a... 详细信息

关键词： Dengue virus Arbovirus Mosquitoes Aedes aegypti Benin

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Atomistic understanding of rough surface on the interfacial friction behavior during the chemical mechanical polishing process of diamond

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Friction 2024年第6期12卷 1119-1132页

作者： Song YUAN Xiaoguang GUO Hao WANG renke KANG Shang GAO State Key laboratory of High-performance Precision Manufacturing Dalian University of TechnologyDalian 116024China

The roughness of the contact surface exerts a vital role in *** is still a significant challenge to understand the microscopic contact of the rough surface at the atomic ***,the rough surface with a special root mean square(RMS)value is constructed by multivariate Weierstrass–Mandelbrot(W–M)function and the rubbing process during that the chemical mechanical polishing(CMP)process of diamond is mimicked utilizing the reactive force field molecular dynamics(ReaxFF MD)*** is found that the contact area A/A0 is positively related with the load,and the friction force F depends on the number of interfacial bridge *** the surface roughness will increase the friction force and friction *** model with low roughness and high lubrication has less friction force,and the presence of polishing liquid molecules can decrease the friction force and friction *** RMS value and the degree of damage show a functional relationship with the applied load and lubrication,i.e.,the RMS value decreases more under larger load and higher lubrication,and the diamond substrate occurs severer damage under larger load and lower *** work will generate fresh insight into the understanding of the microscopic contact of the rough surface at the atomic level.

关键词： diamond random roughness reactive force field molecular dynamics(ReaxFF MD) friction Weierstrass-Mandelbrot(W-M)function chemical mechanical polishing(CMP)

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Enhancing Dense Small Object Detection in UAV Images Based on Hybrid Transformer

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Computers, Materials & Continua 2024年第3期78卷 3993-4013页

作者： Changfeng Feng Chunping Wang Dongdong Zhang renke Kou Qiang Fu Shijiazhuang Campus People Liberation Army Engineering UniversityShijiazhuang050003China School of Information and Intelligent Engineering Sanya UniversitySanya572000China

Transformer-based models have facilitated significant advances in object ***,their extensive computational consumption and suboptimal detection of dense small objects curtail their applicability in unmanned aerial vehicle(UAV)*** these limitations,we propose a hybrid transformer-based detector,H-DETR,and enhance it for dense small objects,leading to an accurate and efficient ***,we introduce a hybrid transformer encoder,which integrates a convolutional neural network-based cross-scale fusion module with the original encoder to handle multi-scale feature sequences more ***,we propose two novel strategies to enhance detection performance without incurring additional inference *** filter is designed to cope with the dense clustering inherent in drone-captured images by counteracting similar queries with a training-aware non-maximum *** denoising learning is a novel enhancement method inspired by adversarial learning,which improves the detection of numerous small targets by counteracting the effects of artificial spatial and semantic *** experiments on the VisDrone and UAVDT datasets substantiate the effectiveness of our approach,achieving a significant improvement in accuracy with a reduction in computational *** method achieves 31.9%and 21.1%AP on the VisDrone and UAVDT datasets,respectively,and has a faster inference speed,making it a competitive model in UAV image object detection.

关键词： UAV images transformer dense small object detection

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Improving fatigue properties of normal direction ultrasonic vibration assisted face grinding Inconel 718 by regulating machined surface integrity

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International Journal of Extreme Manufacturing 2024年第3期6卷 458-475页

作者： Nianwei Xu renke Kang Bi Zhang Yuan Zhang Chenxu Wang Yan Bao Zhigang Dong State Key laboratory of High-Performance Precision Manufacturing Dalian University of TechnologyDalian 116024People’s Republic of China Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China

Fatigue properties are crucial for critical aero-engine components in extreme serviceenvironments,which are significantly affected by surface integrity(SI)indexes(especially surface topography,residual stressσ_(res),and microhardness)after machining ***-direction ultrasonic vibration-assisted face grinding(ND-UVAFG)has advantages in improving the machinability of Inconel 718,but there is a competitive relationship between higher compressiveσ_(res)and higher surface roughness R_(a)in affecting fatigue *** lack of a quantitative relationship between multiple SI indexes and fatigue strength makes theindeterminacy of a regulatory strategy for improving fatigue *** this work,a model of fatigue strength(σ_f)_(sur)considering multiple SI indexes was ***,high-cycle fatigue tests were carried out on Inconel 718 samples with different SI characteristics,and the influence of ND-UVAFG process parameters on SI was *** on SI indexes data,the(σ_f)_(sur)distribution in the grinding surface layer for ND-UVAFG Inconel 718 samples was determined using the developed model,and then the fatigue crack initiation(FCI)sites were *** predicted FCI sites corresponded well with the experimental results,therebyverifying this model.A strategy for improving the fatigue life was proposed in this work,which was to transfer the fatigue source from the machined surface to the bulk material by controlling the SI ***,a critical condition of SI indexes that FCI sites appeared on the surface or in bulk material was given by fitting the predicted *** to the critical condition,an SI field where FCI sites appeared in the bulk material could be *** this field,thefatigue life of Inconel 718 samples could be improved by approximately 140%.

关键词： surface integrity fatigue strength Inconel 718 ultrasonic assisted grinding

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An overview of Web3 technology: Infrastructure, applications, and popularity

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BlOCKCHAIN-RESEARCH AND APPlICATIONS 2024年第1期5卷 97-106页

作者： Huang, renke Chen, Jiachi Wang, Yanlin Bi, Tingting Nie, liming Zheng, Zibin Sun Yat Sen Univ Sch Software Engn Guangzhou 510275 Peoples R China Data61 Canberra ACT 2601 Australia Zhejiang Sci Tech Univ Hangzhou 310018 Peoples R China Nanyang Technol Univ Singapore 639798 Singapore

Web3, the next generation of the Internet, represents a decentralized and democratized web. Although it has garnered significant public interest and found numerous real-world applications, there is a limited understanding of people's perceptions and experiences with Web3. In this study, we conducted an empirical study to investigate the categories of Web3 applications and their popularity, as well as the potential challenges and opportunities within this emerging landscape. Our research was carried out in two phases. In the first phase, we analyzed 200 popular Web3 projects associated with 10 leading Web3 venture capital firms. In the second phase, we collected and examined code-related data from GitHub and market-related data from blockchain browsers (e.g., Etherscan) for these projects. Our analysis revealed that the Web3 ecosystem can be categorized into two groups, i.e., Web3 infrastructure and Web3 applications, with each consisting of several subcategories or subdomains. We also gained insights into the popularity of these Web3 projects at both the code and market levels and pointed out the challenges in the Web3 ecosystem at the system, developer, and user levels, as well as the opportunities it presents. Our findings contribute to a better understanding of Web3 for researchers and developers, which in turn promotes further exploration and advancement in this innovative field.

关键词： Web3 Blockchain Empirical study Survey

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laser-assisted grinding of RB-SiC composites:laser ablation behavior and mechanism

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Chinese Journal of Aeronautics 2024年第1期37卷 362-376页

作者： Zhigang DONG Wenchao SUN Xintong CAI Feng YANG Yan BAO renke KANG Dongjiang WU Guangyi MA Fangyong NIU Key laboratory for Precision and Non-traditional Machining Technology of the Ministry of Education School of Mechanical EngineeringDalian University of TechnologyDalian 116024China

laser ablation is an important process during laser-Assisted Grinding(lAG)of hard and brittle *** realize controllable material removal during laser ablation of RB-SiC composites,ablation experiments under different laser Energy Density(lAED)and lAG experiments are *** rules and mechanism of physical phase,ablation morphology and crack characteristics caused by laser irradiation are *** forces of lAG and Conventional Grinding(CG)are *** results show that ablation surface changes from slight oxidation to obvious material removal with lAED increasing,and ablation depth increases *** ablation products change from submicron SiO_(2)particles to nanoscale particles and *** lAED promotes SiC decomposition and sublimation,which leads to the increase of C *** SiC phase forms corrugated shape in recast layer and columnar shape in Heat Affected Zone(HAZ)at 56 J/mm^(2).The cold and heat cycle leads to formation of fishbone *** ablation specimen under 30 J/mm^(2),the grinding force can be reduced by a maximum of 39%and brittle damage region is *** material removal and microcrack generated will significantly reduce the hardness and improve machinability,which can promote grinding efficiency.

关键词： RB-SiC laser Ceramic Composites Grinding

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The appearance of cytoplasmic cytochrome C precedes apoptosis during Drosophila salivary gland degradation

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Insect Science 2024年第1期31卷 157-172页

作者： Shihui long Wenxin Cao Yongyu Qiu Ruohan Deng Jiali liu lidan Zhang renke Dong Fengxin liu Sheng li Haigang Zhao Na li Kang li Guangdong Provincial Key laboratory of Insect Developmental Biology and Applied Technology Institute of Insect Science and TechnologySchool of Life SciencesSouth China Normal UniversityGuangzhouChina Guangdong laboratory for lingnan Modern Agriculture South China Agricultural UniversityGuangzhouChina Guangmeiyuan R&D Center Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied TechnologySouth China Normal UniversityMeizhouGuangdong ProvinceChina School of Food Science and Engineering South China University of TechnologyGuangzhouChina ChemPartner PharmaTech Co. LtdJiangmenGuangdong ProvinceChina

Apoptosis is an important process for organism development that functions to eliminate cell damage,maintain homeostasis,and remove obsolete tissues during *** mammals,apoptosis is accompanied by the release of cytochrome C(Cyt-c)from mitochondria to the ***,whether this process is conserved in the fruit fly,Drosophila melanogaster,remains *** this study,we discovered that during the degradation of Drosophila salivary gland,the transcription of mitochondria apoptosis factors(MAPFs),Cyt-c,and death-associated APAF1-related killer(Dark)encoding genes are all upregulated antecedent to initiator and effector caspases encoding *** proteins Cyt-c and the active caspase 3 appear gradually in the cytoplasm during salivary gland ***,the Cyt-c protein colocates with mito-GFP,the marker indicating cytoplasmic mitochondria,and the change in mitochondrial membrane potential coincides with the appearance of Cyt-c in the ***,impeding or promoting 20E-induced transcription factor E93 suppresses or enhances the staining of Cyt-c and the active caspase 3 in the cytoplasm of salivary gland,and accordingly decreases or increases the mitochondrial membrane potential,*** research provides evidence that cytoplasmic Cyt-c appears before apoptosis during Drosophila salivary gland degradation,shedding light on partial conserved mechanism in apoptosis between insects and mammals.

关键词： active caspase 3 apoptosis Cyt-c Drosophila salivary gland

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HCCDB v2.0:Decompose Expression Variations by Single-cell RNA-seq and Spatial Transcriptomics in HCC

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Genomics, Proteomics & Bioinformatics 2024年第1期22卷 131-142页

作者： Ziming Jiang Yanhong Wu Yuxin Miao Kaige Deng Fan Yang Shuhuan Xu Yupeng Wang renke You lei Zhang Yuhan Fan Wenbo Guo Qiuyu lian lei Chen Xuegong Zhang Yongchang Zheng Jin Gu Eight-Year Program of Clinical Medicine Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100006China MOE Key laboratory of Bioinformatics BNRIST Bioinformatics DivisionInstitute for Precision Medicine&Department of AutomationTsinghua UniversityBeijing 100084China Department of liver Surgery Peking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Fuzhou Institute for Data Technology Fuzhou 350207China University of Michigan-Shanghai Jiao Tong University Joint Institute Shanghai Jiao Tong UniversityShanghai 200240China Department of Automation Shanghai Jiao Tong UniversityShanghai 200240China International Cooperation laboratory on Signal Transduction Eastern Hepatobiliary Surgery InstituteSecond Military Medical UniversityShanghai 200438China National Center for liver Cancer Shanghai 201805China

large-scale transcriptomic data are crucial for understanding the molecular features of hepatocellular carcinoma(HCC).Integrated 15 transcriptomic datasets of HCC clinical samples,the first version of HCC database(HCCDB v1.0)was released in *** the meta-analysis of differentially expressed genes and prognosis-related genes across multiple datasets,it provides a systematic view of the altered biological processes and the inter-patient heterogeneities of HCC with high reproducibility and *** four years having passed,the database now needs integration of recently published ***,the latest single-cell and spatial transcriptomics have provided a great opportunity to decipher complex gene expression variations at the cellular level with spatial ***,we present HCCDB v2.0,an updated version that combines bulk,single-cell,and spatial transcriptomic data of HCC clinical *** dramatically expands the bulk sample size by adding 1656 new samples from 11 datasets to the existing 3917 samples,thereby enhancing the reliability of transcriptomic meta-analysis.A total of 182,832 cells and 69,352 spatial spots are added to the single-cell and spatial transcriptomics sections,respectively.A novel single-cell level and 2-dimension(sc-2D)metric is proposed as well to summarize cell type-specific and dysregulated gene expression *** are all graphically visualized in our online portal,allowing users to easily retrieve data through a user-friendly interface and navigate between different *** extensive clinical phenotypes and transcriptomic data in the database,we show two applications for identifying prognosis-associated cells and tumor *** v2.0 is available at http://***/database/hccdb2.

关键词： Hepatocellular carcinoma Database Integrative analysis Single-cell RNA sequencing Spatial transcriptomics

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增升装置缝翼噪声机理与控制研究进展

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实验流体力学 2024年第3期38卷 20-37页

作者：魏人可刘宇南方科技大学力学与航空航天工程系深圳518055 中国空气动力研究与发展中心气动噪声控制重点实验室绵阳621000

在飞机着陆过程中,增升装置中的缝翼是机体气动噪声的重要噪声源。近几十年来,国内外研究者针对缝翼噪声开展了大量风洞试验研究,对其噪声特性和机理已有深入认识,并在流动控制和降噪技术方面进行了诸多尝试。本文综述分析了二维翼型缝... 详细信息

在飞机着陆过程中,增升装置中的缝翼是机体气动噪声的重要噪声源。近几十年来,国内外研究者针对缝翼噪声开展了大量风洞试验研究,对其噪声特性和机理已有深入认识,并在流动控制和降噪技术方面进行了诸多尝试。本文综述分析了二维翼型缝翼噪声风洞试验研究方面的主要进展,介绍了3种缝翼噪声成分(低频宽频噪声、高频离散纯音噪声和低频离散纯音噪声)的产生机理。缝翼噪声控制主要有3类思路:第一类是以凹腔填充为代表的整流方法,通过消除或限制回流的产生控制噪声,效果最为显著;第二类是在缝翼尖端干扰剪切层内相干结构的形成;第三类则是从工程可行性出发,通过优化缝道和缝翼结构参数或采用前缘下垂等新构型来控制噪声。未来研究需进一步借助先进测试手段和试验方案,深入认识缝翼凹腔剪切层流动的流声耦合及其与缝翼尾缘相互作用等复杂现象,以获得更为高效的噪声控制技术。

关键词：增升装置缝翼噪声噪声机理噪声控制

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