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Pancreatic transplantation: Brief review of the current evidence

World Journal of Transplantation 2019年第4期9卷 81-93页

作者： Ahmed Aref Tariq Zayan ravi pararajasingam Ajay Sharma Ahmed Halawa Department of Nephrology Sur HospitalSur 411Oman Faculty of Health and Science Institute of Learning and TeachingUniversity of LiverpoolLiverpool L69 3GBUnited Kingdom Department of Transplantation Sheffield Teaching HospitalsSheffield S5 7AUUnited Kingdom Renal Medicine Royal Liverpool University HospitalsLiverpool L7 8XPUnited Kingdom Department of Transplantation Surgery Sheffield Teaching HospitalsSheffield S5 7AUUnited Kingdom

Kidney transplantation is the treatment of choice for management of end-stage renal ***,in diabetic patients,the underlying metabolic disturbance will persist and even may get worse after isolated kidney *** transplantation in humans was first introduced in *** initial outcome was ***,this was changed after the improvement of surgical techniques together with better patient selection and the availability of potent and better-tolerated immune-suppression like cyclosporine and induction *** kidney and pancreas transplantation will not only solve the problem of organ failure,but it will also stabilise or even reverse the metabolic complications of *** kidney and pancreas transplantation have the best long term outcome in diabetic cases with renal ***,at the cost of an initial increase in morbidity and risk of *** transplantation options include pancreas after kidney transplantation and islet cell *** aim by this work to explore various options which can be offered to a diabetic patient with advanced chronic kidney *** work will provide a simplified,yet up-to-date information regarding the different management options for those diabetic chronic kidney failure patients.

关键词： Combined kidney pancrease transplantation Renal transplantation Diabetic kidney disease Diabetes mellitus

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