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Prevalence of hypertension in India:A meta-analysis

World Journal of Meta-Analysis 2013年第2期1卷 83-89页

作者： Tanu Midha Bhola Nath ranjeeta kumari Yashwant Kumar Rao Umeshwar Pandey Department of Community Medicine GSVM Medical College Department of Community Medicine VCSG Government Medical College Department of Community Medicine AIIMS Department of Pediatrics GSVM Medical College Department of Cardiology LPS Institute of Cardiology and Cardiac Surgery

AIM: To determine the prevalence of hypertension in the urban and rural population of ***: Relevant studies were identified through computer based and manual searches using MEDLINE/ Pub Med, Google scholar, EMBASE, Cochrane Library and reference lists of prevalence studies from January 2000 to June 2012. A total of 12 studies were included in the meta-analysis of hypertension in urban India and 10 studies in the analysis of hypertension in rural India after applying the inclusion and exclusion criteria. Estimates of prevalence were calculated using the random effect model for ***: The electronic search using appropriate keywords identified 177 titles for prevalence of hypertension in urban India, of which 165 were excluded, and 133 titles for prevalence in rural India, of which123 were excluded after applying the inclusion criteria. Twelve studies including 125333 subjects were analyzed to assess the prevalence of hypertension in the urban Indian population, whereas ten studies including 24800 subjects were analyzed to determine the prevalence of hypertension in the rural Indian population. The prevalence of hypertension in the urban population was estimated to be 40.8%(95%CI: 40.5%-41.0%) and that of hypertension in the rural population was 17.9%(95%CI: 17.5%-18.3%). It is evident that the prevalence of hypertension is significantly higher in the urban population of India compared to the rural. CONCLUSION: Current evidence suggests that policies and interventions should be prioritized for reduction of hypertension in the adult Indian population, especially the urban population.

关键词： Prevalence Hypertension Meta-analysis India Urban Rural

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Anticancer Activity of Rice Callus Suspension Cultures from Aromatic Varieties and Metabolites Regulated in Treated Cancer Cell Lines

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Rice science 2024年第4期31卷 449-462,I0027-I0030页

作者： Anuradha kumari Wusirika RAMAKRISHNA Department of Biochemistry Central University of PunjabPunjab 151401India

Tissue culture techniques were used to produce large amounts of bioactive compounds with medicinal potential, overcoming space and time constraints for cancer prevention. Rice callus suspension cultures(RCSC) and seed extracts prepared from aromatic rice varieties were used to evaluate the cytotoxic impact on human colon and lung cancer cell lines, as well as a normal control cell line, using Taxol as a positive control. RCSC and seed extracts from two Indian aromatic rice varieties were applied at different concentrations to treat the cancer cell lines and normal lung fibroblasts over varying time intervals. Apoptosis was assessed in 1:5 dilutions of the A549 and HT-29 cell lines treated with RCSC for 72 h, using propidium iodide staining and flow cytometry. RCSC showed a more potent cytotoxic effect than seed extracts with minimal effect on the normal cell line, in contrast to Taxol. Confocal microscopy and flow cytometry further confirmed the apoptotic effect of RCSC. Gas chromatography-mass spectrometry-based metabolic profiling identified metabolites involved in cytotoxicity and highlighted altered pathways. RCSC is proposed as an alternative source for the development of novel anticancer drugs with reduced side effects.

关键词： anticancer cytotoxicity metabolite profiling plant tissue culture rice callus suspension culture secondary metabolite

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Cut-off of body mass index and waist circumference to predict hypertension in Indian adults

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World Journal of Clinical Cases 2014年第7期2卷 272-278页

作者： Tanu Midha Vinay Krishna Bhola Nath ranjeeta kumari Yashwant Kumar Rao Umeshwar Pandey Samarjeet Kaur Department of Community Medicine Government Medical CollegeKannaujUttar Pradesh 209732India Department of Cardiovascular and Thoracic Surgery LPS Institute of CardiologyKanpurUttar Pradesh 208002India Department of Community Medicine VCSGGMS and RISrinagarGarhwalUttarakhand 246174India Department of Community and Family Medicine AIIMSRishikesh 249201India Department of Pediatrics GSVM Medical CollegeKanpurUttar Pradesh 208002India Department of Cardiology LPS Institute of CardiologyKanpurUttar Pradesh 208002India Department of Community Medicine GSVM Medical CollegeKanpurUttar Pradesh 208002India

AIM: To determine the cut-off values of body mass index(BMI) and waist circumference to predict hypertension in adults in north ***: A community based cross-sectional study was conducted in 801 subjects in Kanpur, aged 20 years and above, using multistage stratified random sampling technique. A pre-tested structured question-naire was used to elicit the required information from the study participants and the diagnostic criteria for hypertension were taken according to the Seventh Joint National Committee Report on Hypertension(JNC-7). Receiver operating characteristic(ROC) analysis was used to estimate the cut-off values of BMI and waist circumference to predict ***: The ROC analysis revealed that BMI is a good predictor of hypertension for both men(area under the ROC curve 0.714) and women(area under the ROC curve 0.821). The cut-off values of BMI for predicting hypertension were identified as ≥ 24.5 kg/m2 in men and ≥ 24.9 kg/m2 in women. Similarly, the ROC analysis for waist circumference showed that it is a good predictor of hypertension both for men(area under the ROC curve 0.784) and women(area under the ROC curve 0.815). The cut-offs for waist circumference for predicting hypertension were estimated as ≥ 83 cm for men and ≥ 78 cm for women. Adults with high BMI or high waist circumference had a higher prevalence of hypertension, ***: Simple anthropometric measurements such as BMI and waist circumference can be used for screening people at increased risk of hypertension in order to refer them for more careful and early diagnostic evaluation. Policies and programs are required for primary and secondary prevention of hypertension.

关键词： Anthropometric indices Body mass index Waist circumference Obesity,Hypertension Adults

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Medicinal Effects, Phytochemistry,Pharmacology of Euphorbia prostrata and Promising MolecularMechanisms

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Chinese Journal of Integrative Medicine 2024年第2期30卷 181-192页

作者： Nirmala kumari Yadav Rakesh Yadav Department of Pharmacy Banasthali VidyapithBanasthali(304022)RajasthanIndia Department of Pharmaceutical Sciences Indira Gandhi UniversityMeerpurRewari(122502)HaryanaIndia National Forensic Sciences University Tripura CampusAgartala(799001)TripuraIndia

Euphorbiaceae is a large family of dicotyledonous angiosperms with diverse genera including Euphorbia prostrata(***).Current research has provided scientific evidence for traditional uses of *** against diverse pathological conditions such as anti-hemorrhoidal,anti-inflammatory,analgesic,wound healing,antioxidant,antibacterial,leishmanicidal,antitumor activity,and so *** phytochemical screening has revealed the presence of glycosides,phytosterols,flavonoids,polyphenols,tannins,and anthraquinones with chemical structures elucidation of their respective *** uniqueness of such multifactorial compounds present in this species endorses it as the potent therapeutic or prophylactic choice for several fatal *** ethnomedical applications served as a significant citation for pharmacology,the molecular mechanism has not been reviewed *** present paper provides a comprehensive review of research outcomes,pharmacology,toxicology,and molecular signaling of phytochemicals of *** species as a reference for relevant *** study of bioactive compounds in crude extracts and fractions,the demonstration of primary mechanisms of pharmacology,along with the addition of toxicity,and clinical trials,should be conceded in *** review underlines the *** species that can be a promising phytomedicine since we are committed to excavating more intensely into their pharmacological role.

关键词： Euphorbia prostrata Euphorbiaceae phytochemicals ethnomedical applications toxicology molecularmechanism

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MXenes: Versatile 2D materials with tailored surface chemistry and diverse applications

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Journal of Energy Chemistry 2024年第3期90卷 253-293,I0008页

作者： Sunil Kumar Nitu kumari Yongho Seo Department of Nanotechnology and Advanced Materials Engineering and HMC Sejong UniversitySeoul 05006South Korea School of Studies in Chemistry Jiwaji UniversityGwalior 474011India

MXenes,the most recent addition to the 2D material family,have attracted significant attention owing to their distinctive characteristics,including high surface area,conductivity,surface characteristics,mechanical strength,*** review begins by presenting MXenes,providing insights into their structural characteristics,synthesis methods,and surface functional *** review covers a thorough analysis of MXene surface properties,including surface chemistry and termination group *** properties of MXenes are influenced by their synthesis,which can be fluorine-based or ***-based synthesis techniques involve etching with fluorine-based reagents,mainly including HF or LiF/HCl,while fluorine-free methods include electrochemical etching,chemical vapor deposition(CVD),alkaline etching,Lewis acid-based etching,*** techniques result in the emergence of functional groups such as-F,-O,-OH,-Cl,*** the MXenes surface,depending on the synthesis method *** of MXenes,such as electrical conductivity,electronic properties,catalytic activity,magnetic properties,mechanical strength,and chemical and thermal stability,are examined,and the role of functional groups in determining these properties is *** review delves into the diverse applications of MXenes,encompassing supercapacitors,battery materials,hydrogen storage,fuel cells,electromagnetic interference(EMI) shielding,pollutant removal,water purification,flexible electronics,sensors,additive manufacturing,catalysis,biomedical and healthcare fields,***,this article outlines the challenges and opportunities in the current and future development of MXenes research,addressing various aspects such as synthesis scalability,etching challenges,and multifunctionality,and exploring novel *** review concludes with future prospects and conclusions envisioning the impact of MXenes on future technologies and innovation.

关键词： MXenes 2D materials Surface chemistry MXenes structure Synthesis Applications

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A Spectral Convolutional Neural Network Model Based on Adaptive Fick’s Law for Hyperspectral Image Classification

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Computers, Materials & Continua 2024年第4期79卷 19-46页

作者： Tsu-Yang Wu Haonan Li Saru kumari Chien-Ming Chen School of Artificial Intelligence(School of Future Technology) Nanjing University of Information Science&TechnologyNanjing210044China College of Computer Science and Engineering Shandong University of Science and TechnologyQingdao266590China Department of Mathematics Chaudhary Charan Singh UniversityMeerutUttar Pradesh250004India

Hyperspectral image classification stands as a pivotal task within the field of remote sensing,yet achieving highprecision classification remains a significant *** response to this challenge,a Spectral Convolutional Neural Network model based on Adaptive Fick’s Law Algorithm(AFLA-SCNN)is *** Adaptive Fick’s Law Algorithm(AFLA)constitutes a novel metaheuristic algorithm introduced herein,encompassing three new strategies:Adaptive weight factor,Gaussian mutation,and probability update *** adaptive weight factor,the algorithmcan adjust theweights according to the change in the number of iterations to improve the performance of the *** helps the algorithm avoid falling into local optimal solutions and improves the searchability of the *** probability update strategy helps to improve the exploitability and adaptability of the *** the AFLA-SCNN model,AFLA is employed to optimize two hyperparameters in the SCNN model,namely,“numEpochs”and“miniBatchSize”,to attain their optimal ***’s performance is initially validated across 28 functions in 10D,30D,and 50D for CEC2013 and 29 functions in 10D,30D,and 50D for *** results indicate AFLA’s marked performance superiority over nine other prominent optimization ***,the AFLA-SCNN model was compared with the Spectral Convolutional Neural Network model based on Fick’s Law Algorithm(FLA-SCNN),Spectral Convolutional Neural Network model based on Harris Hawks Optimization(HHO-SCNN),Spectral Convolutional Neural Network model based onDifferential Evolution(DE-SCNN),SpectralConvolutionalNeuralNetwork(SCNN)model,and SupportVector Machines(SVM)model using the Indian Pines dataset and PaviaUniversity *** experimental results show that the AFLA-SCNN model outperforms other models in terms of Accuracy,Precision,Recall,and F1-score on Indian Pines and Pavia *** them,the Accuracy of the AFLA-SCNN model on India

关键词： Adaptive Fick’s law algorithm spectral convolutional neural network metaheuristic algorithm intelligent optimization algorithm hyperspectral image classification

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Microalgal bioinoculants for sustainable agriculture and their interactions with soil biotic and abiotic components:A review

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Pedosphere 2024年第2期34卷 297-314页

作者： Shisy JOSE Nirmal RENUKA Sachitra Kumar RATHA Sheena kumari Faizal BUX Institute for Water and Wastewater Technology Durban University of TechnologyP.O.Box 1334Durban 4000South Africa Algal Biotechnology Laboratory Department of BotanyCentral University of PunjabBathinda 151401India Phycology Laboratory Council of Scientific and Industrial Research-National Botanical Research InstituteLucknowUttar Pradesh 226001India

Modern agricultural practices have posed a detrimental impact on the environment due to their intensive use to meet the food demands of an ever-increasing *** this context,microalgal bioinoculants,specifically cyanobacteria and green microalgae,have emerged as sustainable options for agricultural practices to improve soil organic carbon,nutrient availability,microbial quality,and plant *** overview of current and future perspectives on the use of microalgal bioinoculants in agriculture practices is presented in this review,along with a discussion of their interactions with soil biotic and abiotic factors that affect soil fertility,plant health,and crop *** benefits of microalgal bioinoculants include releasing agronomically important metabolites(exopolymers and phytohormones)as well as solubilizing soil ***,they function as biocontrol agents against soil-borne pathogens and facilitate the establishment of rhizosphere communities of agricultural *** far,very few studies have explored the basic mechanisms by which microalgal bioinoculants interact with soil biotic and abiotic *** recent years,advanced molecular techniques have contributed to a better understanding of these interactions.

关键词： biocontrol agent biofertilizer cyanobacteria microalgae microbial community molecular technique plant growth soil fertility

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Electrokinetic-mechanism of water and furfural oxidation on pulsed laser-interlaced Cu_(2)O and CoO on nickel foam

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Journal of Energy Chemistry 2024年第4期91卷 145-154页

作者： Yewon Oh Jayaraman Theerthagiri M.L.Aruna kumari Ahreum Min Cheol Joo Moon Myong Yong Choi Department of Chemistry(BK21 FOUR) Research Institute of Natural SciencesGyeongsang National UniversityJinju 52828Republic of Korea Department of Chemistry The Oxford College of ScienceBengaluruKarnataka 560102India Core-Facility Center for Photochemistry&Nanomaterials Gyeongsang National UniversityJinju 52828Republic of Korea

The electrocatalytic oxidation of biomass-derived furfural(FF)feedstocks into 2-furoic acid(FA)holds immense industrial potential in optics,cosmetics,polymers,and ***,we fabricated Co O/Ni O/nickel foam(NF)and Cu_(2)O/Ni O/NF electrodes via in situ pulsed laser irradiation in liquids(PLIL)for the bifunctional electrocatalysis of oxygen evolution reaction(OER)and furfural oxidation reaction(FOR),*** oxidation of NF surface to NiO and deposition of CoO and/or Cu_(2)O on NF during PLIL offer distinct advantages for enhancing both the OER and ***/NiO/NF electrocatalyst provides a consistently low overpotential of~359 m V(OER)at 10 m A/cm^(2),achieving the maximum FA yield(~16.37 m M)with 61.5%selectivity,79.5%carbon balance,and a remarkable Faradaic efficiency of~90.1%during 2 h of FOR at 1.43 V(*** hydrogen electrode).Mechanistic pathway via in situ electrochemical-Raman spectroscopy on CoO/NiO/NF reveals the involvement of phase transition intermediates(NiOOH and CoOOH)as surface-active centers during electrochemical *** carbonyl carbon in FF is attacked by hydroxyl groups to form unstable hydrates that subsequently undergo further oxidation to yield FA *** method holds promise for large-scale applications,enabling simultaneous production of renewable building materials and fuel.

关键词： Pulsed laser irradiation in liquids Water and furfural oxidation In situ Raman spectroscopy CoO/NiO/nickel foam Cu_(2)O/Nio/nickel foam 2-furoic acid

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New insights into nitric oxide biosynthesis underpin lateral root development

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Molecular Plant 2024年第5期17卷 691-693页

作者： Kapuganti Jagadis Gupta Nidhi Yadav Aprajita kumari Gary J.Loake National Institute for Plant Genome Research Aruna Asaf Ali MargNew Delhi 110070India Institute of Molecular Plant Sciences School of Biological SciencesUniversity of EdinburghEH93BF EdinburghUK Centre for Engineering Biology School of Biological SciencesUniversity of EdinburghEH93BF EdinburghUK

In recent years,nitric oxide(NO)has emerged as a key redox signaling molecule in plants functioning in the regulation of key developmental programs and the orchestration of responses to a plethora of environmental cues(Kolbert et al.,2019).The predominant route for the transfer of NO bioactivity is through S-nitrosylation,the addition of an NO moiety to a protein cysteine thiol to form an S-nitrosothiol(Yun et al.,2011).Specificity for this process is established by the structural constraints imposed by tertiary protein structure in gating access to given cysteine redox switches and associated proteins that can either facilitate the addition or removal of the NO moiety at these residues(Umbreen et al.,2018).

关键词： moiety addition redox

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GeMemiOM: the curated database on genes, putative methylation study targets, and microRNA targets for otitis media

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Journal of Genetics and Genomics 2024年第2期51卷 260-263页

作者： Kondyarpu Abhishek Bineet Kumar Mohanta Pratima kumari Anshuman Dixit Puppala Venkat Ramchander Institute of Life Sciences Nalco SquareChandrasekharpurBhubaneswarIndia Regional Center for Biotechnology FaridabadHaryanaIndia

Otitis media(OM),the most underrated middle ear disease,often onsets during childhood and gets complicated in susceptible *** of the middle ear(ME)leads to its degradation and abnormal physiological *** ME inflammation sometimes results in lethal secondary complications(Penido et al.,2016).OM is a corroboration of multiple facets that leads to disabling hearing loss and associated *** of the facets constituted are genetic,epigenetic,immunogenetic,anatomical.

关键词： inflammation media

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