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Experimental infection with Yersinia pseudotuberculosis in European brown hare(Lepus europaeus,Pallas)

Asian Pacific Journal of Tropical Medicine 2017年第3期10卷 269-274页

作者： Filippo Fratini ranieri verin Valentina V.Ebani Cecilia Ambrogi Fabrizio Bertelloni Barbara Turchi Alessandro Poli Domenico Cerri Dipartimento di Scienze Veterinarie Universita di PisaPisa Italy Department of Veterinary Pathology and Public Health Institute of Veterinary ScienceUniversity of LiverpoolUK Corpo Forestale dello Stato Azienda Faunistica di MontefalconePisaItaly

Objective:To investigate clinicopathological,bacteriological and pathological aspects of an experimental infection with Yersinia pseudotuberculosis(***)in hares in order to verify the efficacy of serology for the in vivo ***,the pathogenicity of two *** strains was investigated in order to detect potential ***:Twelve European brown hares(Lepus europaeus,Pallas)were experimentally infected per os and via conjunctival mucosae with ***:six subjects were infected with a strain isolated from a naturally infected hare(YpH)and six subjects with a strain isolated from a naturally infected rabbit(YpR).Two hares were used as negative *** animals were subjected to clinical,bacteriological and serological examinations during 9 weeks following the infection and,at the end of the control period,subjects still alive were euthanized and submitted to a complete post mortem ***:All faecal samples collected during the control period were positive for bacteriological examinations and to a PCR for the inv gene of ***,while only one Yp H-infected hare showed a positive *** the 2nd to the 9th week post infection(pi),serological analysis revealed specific antibodies with titers ranging from 1:10 to 1:160 in all YpH-infected and two YpR-infected *** the Yp H-infected and two Yp R-infected hares scored positive for *** by means of bacteriological ***,suppurative multifocal lesions were detected in liver,spleen,kidney and sub-mandibular lymph nodes in both YpH-and YpR-infected hares and confirmed with *** lesions were observed only in Yp H-infected *** confirmed the presence of bacterial antigen in all infected ***:Results of this study revealed that YpH strain is more pathogenic for hares than the YpR strain;moreover the serological test performed in

关键词： Yersinia pseudotuberculosis Hare Bacteriology Serology Histopathology Immuno histochemistry

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Quantification of Total Phenols, Total Flavonoids, Total Anthocyanins and Evaluation of Antioxidant and Antiradical Activities of Detarium Senegalense Extracts from Chad

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Advances in Biological Chemistry 2024年第1期14卷 1-15页

作者： Salomon Madjitoloum Betoloum Séverin Mbaihougadobe Abel Mbaiogaou Djibrine Adoum Oumar Mbaindiguim Dagoto Yaya Mahmout Laboratory of Research on Natural Substances Faculty of Exact and Applied Sciences (F.E.A.S) University of N’Djamena N’Djamena Chad Department of Chemistry University of Moundou Moundou Chad

The aim of the present work is to assess the value of Detarium Senegalense by determining the content of total phenols, total flavonoids and total anthocyanins, and by evaluating the free radical scavenging activity of Detarium Senegalense extracts. For this purpose, sequential extraction using solvents of increasing polarity was essential. The various extracts obtained underwent phytochemical and biochemical analyses. Phytochemical screening revealed the presence of flavonoids, alkaloids, tannins, polyphenols, anthocyanins and steroids/terpenes. Quantitative analysis of total polyphenols, total flavonoids and total anthocyanins yielded the following results: total flavonoids (0.803 ± 0029 mg EQ/100g P for acetone extract of roots and 0.871 ± 0.401 mg EQ/100g P for methanol extract of leaves);total polyphenols (23.298 ± 12.68 mg EAG/100g P for acetone extract of roots and 24.69 ± 0.49 401 mg EAG/100g P for methanol extract of leaves);total monomeric anthocyanins (44.697 ± 0.939 mg EC3G/100g P and 16.699 ± 0.193 mg EC3G/100g P respectively for acetone and methanol extracts of stem bark). DPPH free radical scavenging activity was 1.674 ± 0.023 mg/mL for the acetone extract and 0.934 ± 0.24 mg/mL for the methanol extract of roots. .

关键词： Total Phenols Total Flavonoids Total Anthocyanins Antioxidant and Anti-Radical Activities Detarium Senegalense Chad

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GIS-Based Multi-Criteria Decision Analysis (MCDA) and Analytical Hierarchy Process (AHP) Techniques to Derive Flood Risks Management on Rice Productivity in Gishari Marshland

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Journal of Geoscience and Environment Protection 2024年第3期12卷 222-249页

作者： Jean Nepo Nsengiyumva Emmanuel Nshimiyimana Jean Marie Ntakirutimana Phocas Musabyimana Yvonne Akimana Fred Shema Set Niyitanga Séverin Hishamunda Callixte Musinga Mpamabara Eliezel Habineza Department of Agricultural Engineering Rwanda Polytechnic IPRC Gishari Rwamagana Rwanda Department of Environmental Information System University of Lay Adventist of Kigali Kigali Campus Kigali Rwanda School of Environmental Science and Engineering Department of Environmental Engineering Suzhou University of Science and Technology Suzhou China Department of Agricultural and Resources Economics School of Agriculture and Environmental Sciences Jomo Kenyatta University of Agriculture and Technology Kigali Campus Kigali Rwanda Department of Smart Agriculture System Hankyong National University Anseong Kyonggi South Korea

Floods are phenomenon with significant socio-economic implications mainly for human loss, agriculture, livestock, soil loss and land degradation, for which many researchers try to identify the most appropriate methodologies by analyzing their temporal and spatial development. This study therefore attempts to employ the GIS-based multi-criteria decision analysis and analytical hierarchy process techniques to derive the flood risks management on rice productivity in the Gishari Agricultural Marshland in Rwamagana district, Rwanda. Here, six influencing potential factors to flooding, including river slope, soil texture, Land Use Land Cover through Land Sat 8, rainfall, river distance and Digital Elevation Model are considered for the delineation of flood risk zones. Data acquisition like Landsat 8 images, DEM, land use land cover, slope, and soil class in the study area were considered. Results showed that if the DEM is outdated or inaccurate due to changes in the terrain, such as construction, excavation, or erosion, the predicted flood patterns might not reflect the actual water flow. This could result unexpected flood extents and depths, potentially inundating rice fields that were not previously at risk and this, expectedly explained that the increase 1 m in elevation would reduce the rice productivity by 0.17% due to unplanned flood risks in marshland. It was found that the change in rainfall distribution in Gishari agricultural marshland would also decrease the rice productivity by 0.0018%, which is a sign that rainfall is a major factor of flooding in rice scheme. Rainfall distribution plays a crucial role in flooding analysis and can directly impact rice productivity. Oppositely, another causal factor was Land Use Land Cover (LULC), where the Multivariate Logistic Regression Model Analysis findings showed that the increase of one unit in Land Use Land Cover would increase rice productivity by 0.17% of the total rice productivity from the Gishari Agricultural Ma

关键词： Multi Criteria Decision Analysis (MCDA) Analytical Hierarchy Analysis (AHA) GIS RS and DEM

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Phytochemical Screening, Study of Acute Toxicity and Hypoglycemic and Antihyperglycemic Activities of Silver Nanoparticles from Guibourtia tessmannii (Harms) J. Leonard (Caesalpiniaceae)

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Open Journal of Applied Sciences 2024年第1期14卷 118-130页

作者： Ngoulé Charles Christian Eya’ane Meva François Sone Enone Bertin Ngo Nyobe Biwole Caroline Tankeu Séverin Elisée Songue Pascal Nguene Jean Pierre Etame-Loe Gisèle Department of Pharmaceutical Sciences Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Biology of Plant Organisms Faculty of Sciences University of Douala Douala Cameroon

According to the World Health Organization, diabetes affects approximately 347 million people worldwide. Its management is not within the reach of all social classes, therefore medicinal plants are still the first resort for many populations in Africa. The biological material used in this study was the trunk bark of Guibourtia tessmannii. 50 g of trunk bark powder were decocted in 500 ml of distilled water for 5 minutes were carried out. The method used for the synthesis of silver nanoparticles (AgNps) was an organometallic bio-reduction of silver nitrate salts mediated by various secondary metabolites contained in the plant extract. The study of the toxicity acute was conducted according to guideline 423 of the OECD protocol. The pharmacological activities were each carried out with 28 female rats divided into 7 groups of four rats. It was a question for the hypoglycemic activity of administering various doses of silver nanoparticles and other substances to the rats thirty minutes after the carbohydrate intake and for the anti-hyperglycemic activity of administering the same substances to the rats thirty minutes before the carbohydrate intake. The extraction yield was 8.76%. Only the alkaloid test was negative. After acute toxicity study, the LD50 was greater than 2000 mg/kg. Blood sugar tests revealed that glibenclamide 5 mg/kg, which is the reference molecule, lowered blood sugar more than the other treatments applied in the other batches. It was followed by treatment with silver nanoparticles at a dose of 400 μg/kg in both tests. It was therefore concluded that silver nanoparticles from G. tessmannii are good for the formulation of improved traditional medicines and bring up their afficacity .

关键词： Guibourtia tessmannii Nanoparticles Hypoglycemia Anti-Hyperglycemia

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Emphysematous Cystitis: Report of Two Cases and Review of the Literature

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Health 2024年第4期16卷 309-318页

作者： Roland Bertile Banga-Mouss Nestor Ghislain Andzouana Mbamognoua Yanick Dimi Nyanga Armel Melvin Atipo Ondongo Steve Aristid Ondziel-Opara Raïssa Laure Mayanda Ohouanda Nick Arnaud Monabeka Evariste Bouenizabila Anani Séverin Wences Odzébé Prosper Alain Bouya Urology Department University Hospital of Brazzaville Brazzaville Republic of the Congo Faculty of Health Sciences Marien Ngouabi University Brazzaville Republic of the Congo Department of Metabolic and Endocrine Diseases University Hospital of Brazzaville Brazzaville Republic of the Congo

Emphysematous cystitis is a rare complication of lower urinary tract infection whose prognosis is conditioned by the delay in treatment. The predisposition of diabetic patients to urinary infections caused by gas-producing bacteria is considered one of the most common factors in the occurrence of emphysematous cystitis. The currently recommended diagnostic test is CT scanning, which has definite value in assessing gas accumulation in the bladder wall and lumen. The authors report the observations of two patients aged 68 and 80 who were treated for emphysematous cystitis complicating diabetes mellitus. The evolution was favorable under treatment with antibiotic therapy, insulin therapy and bladder drainage.

关键词： Emphysematous Cystitis Computed Tomography Lower Urinary Tract Infection Diabetes Mellitus

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Management of Testicular Cancers in Brazzaville

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Open Journal of Urology 2024年第5期14卷 324-332页

作者： Roland Bertile Banga-Mouss Yanick Dimi Nyanga Brice Nkoua Epala Armel Melvin Atipo Ondongo Steve Aristid Ondziel-Opara Eliane Ndounga Alexis Bolenga Louis Constant Mbele Mantsouaka Judith Nsonde Malanda Aanani Séverin Wencesl Odzébé Prosper Alain Bouya Departement of Urology and Andrology University Hospital of Brazzaville Brazzaville Republic of the Congo Departement of Medicale Oncology and Radiotherapy University Hospital of Brazzaville Brazzaville Republic of the Congo

Introduction: Testicular cancer accounts for 5% of urological tumors, predominantly affecting young men. The aim of our study was to report the diagnostic and evolutionary aspects of testicular cancer cases treated in our center. Patients and Methods: A retrospective study conducted over a 15-year period involving 12 patients treated for testicular cancer at the University Hospital of Brazzaville. Results: The median age was 31 years (range 11 to 49 years), with a median consultation delay of 10.6 months (range 3 to 27 months). Scrotal mass was the most common reason for consultation. Cancer was bilateral in two patients. Two patients were admitted with metastatic disease. Histopathological examination favored germ cell tumors in 7 cases, two cases of non-Hodgkin’s malignant lymphoma, and one case of epididymo-testicular adenocarcinoma. Adjuvant chemotherapy resulted in complete remission in patients with germ cell tumors. However, neoadjuvant chemotherapy was not effective in patients admitted with advanced-stage disease. Conclusion: Testicular cancer is a rare condition that is curable in the majority of cases, but its management is often complicated in our setting due to delayed diagnosis caused by taboos surrounding genital organ pathologies.

关键词： Testicular Cancer Germ Cell Tumor Cisplatin Testicular Lymphoma Testicular Adenocarcinoma

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Soil organic carbon storage in forest restoration models and environmental conditions

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Journal of Forestry Research 2022年第4期33卷 1123-1134页

作者： ranieri Ribeiro Paula Miguel Calmon Maria Leonor Lopes-Assad Eduardo de SáMendonça Departamento de Agronomia Programa de Pós-Graduação em Produção VegetalUniversidade Federal do Espírito SantoAlto UniversitárioGuararemaAlegreEspírito Santo CEP 29500-000Brazil World Resources Institute SalvadorBahia CEP 40290-040Brazil Departamento de Recursos Naturais e Proteção Ambiental Universidade Federal de São CarlosArarasSão Paulo CEP 13600-970Brazil

The scale of forest and landscape restoration is expected to increase during the UN Decade on Ecosystem Restoration and its contribution to the provision of critical ecosystem services to *** models of forest restoration may improve ecosystem services,including soil organic carbon(SOC)storage.A review was carried out to access:(1)the variability of SOC storage between worldwide forest restoration models and,(2)the effects of climate,soil class,soil texture,and vegetation type on SOC *** reviewed 119 primary studies with information on SOC and soil texture for different forest restoration *** restoration models were grouped into four categories:natural regeneration,monocultures,agroforestry,and mixed *** data was extracted from these four restoration models,other land uses(cropland,bare land,grassland,and natural forest),climate regimes,and soil *** SOC storage in the forest restoration models and other land uses at a global scale ranged between 0.1 to 514 Mg ha^(-1).The overall mean value for SOC storage was higher for natural regeneration(112 Mg ha^(-1)),followed by agroforestry(74 Mg ha^(-1)),mixed forest(73 Mg ha^(-1)),and monocultures(68 Mg ha^(-1)).However,the average SOC storage was similar among the four restoration models in the moist warm climate *** SOC storage mean value in the moist cool zone was 23%higher than the dry cool zone(81 and 62 Mg ha^(-1),respectively),and 50%higher for the moist warm zone when compared to the dry warm climatic zone(74 and 38 Mg ha^(-1),respectively).The SOC storage of the restoration models was positively related to soil depth(0.59;p<0.01),clay content(0.29;p<0.01),and stand age(0.17;p<0.01).Globally,the mean values of SOC storage were 26,66,and 139 Mg ha^(-1) at zero-10,zero-30,and zero-100 cm depths,*** addition,sandy soils showed smaller mean values of SOC storage than medium to clay soils,especially in deeper soil ***,SOC storage was positively re

关键词： Forest restoration Land uses Soil type Soil texture Climate

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The challenges on operating a zero net energy building facing global warming conditions

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Building Simulation 2022年第3期15卷 435-451页

作者： Alberto Hernandez Neto Luciane Cleonice Durante Ivan Julio Apolonio Callejas Emeli Lalesca Aparecida da Guarda JoséVinnicius ranieri Moreira Escola Politécnica University of São PauloBrazil Federal University of Mato Grosso Brazil Federal University of Santa Catarina Brazil

This study proposes a methodology to evaluate the energy performance of existing Zero Energy Buildings and to prospect retrofit strategies in a Savannah climate,concerning the A2 scenario of emissions from the Fourth Report of the Intergovernmental Panel on Climate *** selected building to study is recognized for its high energy performance,named Centro SEBRAE de Sustentabilidade(CSS).Two efficient measures were considered:(i)improvement in the air conditioning system coefficient of performance(COP)and(ii)in the energy efficiency of the photovoltaic plates of generation *** methodology is grounded in the potential bioclimatic concept and the employed steps applied were:preparation of climate archives in the 2020,2050 and 2080 time-slices;calibration of the computational model;evaluation of the retrofit strategies on its energy consumption efficiency through computer *** the CSS has already attended mostly the bioclimatic strategies for the local climate and has high efficiency measures in its systems,the retrofit focused the air conditioning and PV *** isolated retrofit of the air conditioning system was unable to guarantees the NZEB condition despite providing an adequate level of energy efficiency until *** retrofit of the PV system was the only one that provides the NZEB condition for climate change *** contribution of this paper is to provide a guide to be used in NZEBs,with measures of optimization that provide high potential bioclimatic face to the local where it is built,making it possible to maintain this condition in scenarios of global warming.

关键词： sustainable constructions potential bioclimatic building energy consumption weather scenarios

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Role of PTX3 and complement modulation in the tumor microenvironment

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BIOCELL 2022年第10期46卷 2235-2239页

作者： GIUSEPPE STEFANO NETTI FEDERICA SPADACCINO VALERIA CATALANO GIUSEPPE CASTELLANO GIOVANNI STALLONE ELENA ranieri Clinical Pathology Unit and Center for Molecular Medicine Department of Medical and Surgical SciencesUniversity of FoggiaFoggia71122Italy Nephrology Dialysis and Renal Transplant UnitDepartment of Clinical Sciences and Community HealthFondazione IRCCS Ca’Granda-OspedaleMaggiore Policlinico-University of MilanMilan20122Italy Nephrology Dialysis and Transplantation Unit Advanced Research Center on Kidney Aging(A.R.K.A.)Department of Medical and Surgical SciencesUniversity of FoggiaFoggia71122Italy

Pentraxin-3(PTX3),the prototype of long pentraxins,seems to influence complement system(CS)***3 and CS sustain carcinogenesis,enriching tumor microenvironment(TME)with pro-inflammatory molecules promoting angiogenesis in prostate cancer(PC)and renal cell carcinoma(RCC).Furthermore,cancer cells overexpress complement regulatory proteins,such as CD46,CD55 and CD59,which negatively affect complement pathways for support cancer cells *** viewpoint aims to elucidate the ambivalent role of PTX3 and the CS in the context of tumor microenvironment(TME).

关键词： Pentraxin-3 Complement system Tumor microenvironment Prostate cancer Renal cell carcinoma

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Hyperthermic intraperitoneal chemotherapy and colorectal cancer:From physiology to surgery

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World Journal of Clinical Cases 2022年第30期10卷 10852-10861页

作者： Giorgio Ammerata Rosalinda Filippo Carmelo Laface Riccardo Memeo Leonardo Solaini Davide Cavaliere Giuseppe Navarra Girolamo ranieri Giuseppe Currò Michele Ammendola Department Digestive Surgery UnitUniversity“Magna Graecia”Medical SchoolCatanzaro 88100Italy Interventional Oncology Unit with Integrated Section of Translational Medical Oncology National Cancer Research Centre“Giovanni Paolo Ⅱ”Bari 70124Italy Hepato-Biliary and Pancreatic Surgical Unit “F.Miulli”HospitalAcquaviva delle FontiBari 70124Italy Department of Medical and Surgical Sciences University of BolognaForlì40126Italy Department of General and Oncologic Surgery Morgagni-Pierantoni HospitalForlì47121Italy Department of Human Pathology of Adult and Evolutive Age Surgical Oncology Division“G.Martino”HospitalUniversity of MessinaMessina 98122Italy

The pursuit of this paper is to collect principal reviews and systematic reviews about hyperthermic intraperitoneal chemotherapy(HIPEC) and cytoreductive surgery(CRS) used in colorectal cancer(CRC).We focus on principal biological aspects of CRC,hyperthermia effects,and surgical *** searched PubMed/MEDLINE for the principal reviews and systematic reviews published from 2010 to 2021 regarding the bimodal treatment(CRS + HIPEC) against local and advanced *** the literature,from several studies,it seems that the efficacy of bimodal treatment with an accurate CRS can extend overall *** these studies,there are not still any straight guidelines more detailed and scheduled about the use of combined treatment in patients with *** if the concept is still not very clear and shared,after a careful evaluation of the published data,and after some technical and pathophysiological descriptions,we concluded that it is possible to improve the overall survival and quality of life and to reduce the tumor relapse in patients affected by locally advanced(pT4) CRC with peritoneal metastases.

关键词： Hyperthermic intraperitoneal chemotherapy Colorectal cancer Peritoneum Cytoreductive surgery

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