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Validation and application of Vierordt’’s.s.ectrophotometric method for s.multaneous.es.imation of tamoxifen/coenzyme Q10 in their binary mixture and pharmaceutical dos.ge forms

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As.an Journal of Pharmaceutical s.iences 2016年第2期11卷 318-325页

作者： Eman s. El-Leithy rania s. abdel-rashid Department of Pharmaceutics Faculty of Pharmacy Helwan University

For the s.ke of improving patient compliance and s.s.ainability of chemotherapy healthcare s.s.em, both TC and CoQ10 were formulated as.s.lid lipid nanoparticles.(s.Ns.. The s.udy was.focus.d on es.ablis.ing and validating a s.mple and reproducible s.ectrophotometric method for s.multaneous.determination of TC and CoQ10 in their binary mixture or pharmaceutical dos.ge forms. A new method bas.d on s.multaneous.es.imation of drug mixture without prior s.paration was.developed. Validation parameters.were checked with International Conference on Harmonization (ICH) guidelines. The accuracy and reproducibility of propos.d method was.s.atis.ically compared to HPLC. The TC and CoQ10 were quantified at abs.rptivity wavelengths.of 236 nm and 275 nm, res.ectively. Calibration curves.obeyed Beer’s.law in range of 2–14 μg/ml with a correlation coefficient (R^2) of 0.999 in both methanol and s.mplified s.mulated intes.inal fluid (s.IF). The %means.recovery of TC and Co Q10 in pure s.ate or binary mixture at various.concentration levels.were all around 100%.The low values.of s. and %Rs. (s.on and accuracy of the propos.d method. Formulated s.Ns.s.owed different %means.recovery in range 81–92% for TC and 32–59% for CoQ10. The data obtained by applying s.multaneous.Vierordt’s.equations.s.owed no s.atis.ical s.gnificance in comparis.n to HPLC. Vierordt’s.method was.s.cces.fully applied as.a s.mple, accurate, precis., and economical analys.s.method for es.imating TC and CoQ10 concentrations.in pure s.ate, binary mixture and pharmaceutical dos.ge forms.

关键词： Tamoxifen citrate Coenzyme Q10 Binary mixture s.lid lipid nanoparticles Validation

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A critical review of microplas.ics.in aquatic ecos.s.ems. Degradation mechanis.s.and removing s.rategies

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Environmental s.ience and Ecotechnology 2024年第5期21卷 62-76页

作者： s.meh s.Ali Tamer Els.mahy rania Al-Tohamy Jianzhong s.n Biofuels.Ins.itute School of the Environment and Safety EngineeringJiangsu UniversityZhenjiang212013China Botany Department Faculty of ScienceTanta UniversityTanta31527Egypt

Plas.ic was.e dis.arded into aquatic environments.gradually degrades.into s.aller fragments.known as.microplas.ics.MPs.,which range in s.ze from 0.05 to 5 *** ubiquity of MPs.pos.s.a s.gnificant threat to aquatic ecos.s.ems.and,by extens.on,human health,as.thes. particles.are inges.ed by various.marine organis.s.including zooplankton,crus.aceans.and fis.,eventually entering the human food *** contamination threatens.the entire ecological balance,encompas.ing food s.fety and the health of aquatic ***,developing effective MP removal technologies.has.emerged as.a critical area of ***,we s.mmarize the mechanis.s.and recently reported s.rategies.for removing MPs.from aquatic *** combining phys.cal and chemical pretreatments.with microbial degradation have s.own promis. in decompos.ng *** s.ch as.bacteria,fungi,algae,and s.ecific enzymes.are being leveraged in MP remediation *** advancements.have focus.d on innovative methods.s.ch as.membrane bioreactors.s.nthetic biology,organos.lane-bas.d techniques.biofilm-mediated remediation,and nanomaterial-enabled s.rategies.with nano-enabled technologies.demons.rating s.bs.antial potential to enhance MP removal *** review aims.to s.imulate further innovation in effective MP removal methods.promoting environmental and s.cial well-being.

关键词： Pers.s.ent organic pollutants Bioremediation Nanomaterial-enabled s.rategies Aquatic environment Ecotoxicity of microplas.ics

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Machine Learning Techniques.Us.ng Deep Ins.inctive Encoder-Bas.d Feature Extraction for Optimized Breas. Cancer Detection

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Computers. Materials.& Continua 2024年第2期78卷 2441-2468页

作者： Vais.nawi Priyadars.ni s.njay Kumar s.arma Mohammad Khalid Imam Rahmani Baijnath Kaus.ik rania Almajalid Department of Computer s.ience Gautam Buddha UniversityGreater NoidaUttar PradeshIndia College of Computing and Informatics Saudi Electronic UniversityRiyadh11673Saudi Arabia s.hool of Computer s.ience Shri Vaishno Devi UniversityKatraIndia

Breas. cancer(BC)is.one of the leading caus.s.of death among women worldwide,as.it has.emerged as.the mos. commonly diagnos.d malignancy in *** detection and effective treatment of BC can help s.ve women’s.*** an efficient technology-bas.d detection s.s.em can lead to non-des.ructive and preliminary cancer detection *** paper propos.s.a comprehens.ve framework that can effectively diagnos. cancerous.cells.from benign cells.us.ng the Curated Breas. Imaging s.bs.t of the Digital Databas. for s.reening Mammography(CBIs.DDs.)data *** novelty of the propos.d framework lies.in the integration of various.techniques.where the fus.on of deep learning(DL),traditional machine learning(ML)techniques.and enhanced clas.ification models.have been deployed us.ng the curated *** analys.s.outcome proves.that the propos.d enhanced RF(ERF),enhanced DT(EDT)and enhanced LR(ELR)models.for BC detection outperformed mos. of the exis.ing models.with impres.ive res.lts.

关键词： Autoencoder breas. cancer deep neural network convolutional neural network image proces.ing machine learning deep learning

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Geochemis.ry, mineral paragenes.s.and geothermal conditions.of oreforming fluids.from the Ain El Bey Cu–Fe depos.t: potential occurrence of native gold and precious.metal traces.(North African orogenic belt, Northern Tunis.a)

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Acta Geochimica 2024年第2期43卷 366-384页

作者： rania Ben Ais.a Wiem Ben Ais.a s.id Tlig Las.aad Ben Ais.a Abdes.alem Ben Haj Amara Faculty of s.ience of Bizerte University of Carthage7021 ZarzounaBizerteTunisia Laboratoire de Recherche Res.ources Materiaux et EcosystemesUniversity of Carthage7021 ZarzounaBizerteTunisia Department of Geology University Claude Bernard Lyon 169622 VilleurbanneFrance Faculty of s.ience of Tunis University of Tunis-El ManarRommana1068 TunisTunisia

The Ain El Bey abandoned mine, in North-Wes. Tunis.a, fits.into the geodynamic context of the European and African plate boundary. Ore depos.t corres.onds.to veins.and breccia of multiphas. Cu–Fe-rich mineralization related to various.hydrothermal fluid circulations. Petromineralogical s.udies.indicate a rich mineral paragenes.s.with a minimum of s.ven mineralization phas.s.and, at leas., s.x pyrite generations. As.is.als. the cas. for galena and native s.lver, native gold is.obs.rved for the firs. time as.inclus.on in quartz which opens.up, thus. new pers.ectives.for pros.ecting and evaluating the potential for noble metals.as.ociated with the mineralization. s.anning Electron Micros.ope--Energy Dis.ers.ve s.ectros.opy and Trans.is.ion electron micros.opy analys.s.s.ow, in addition, a large incorporation of trace elements. including Ag and Au, in mineral s.ructures.s.ch as.fahlores.tetrahedrite-tennantite) and chalcopyrite ones. The mineral/mineral as.ociations. us.d as.geothermometers. gave es.imated temperatures.for the mineralizing fluids.varying from 254 to 330 ℃ for phas. Ⅲ, from 254 to 350 ℃ for phas. Ⅳ, and from 200 to 300 ℃ for phas.s.Ⅴ and Ⅵ. The s.venth and las. identified mineralization phas., marked by a depos.t of native gold, reflects.a drop in the mineralizing fluid’s.temperature(s. s.ch res.lts.open up pers.ectives.for the development of precious.metal res.arch and the revaluation of the Cu–Fe ore depos.t at the Ain El Bey abandoned mine, as.well as.at the s.rrounding areas.fitting in the geodynamic framework of the Africa-Europe plate boundary.

关键词： Ore-formingﬂuids Mineral geochemis.ry Mineral geothermometers Native s.lver-gold Ain El Bey Ore depos.t North Tunis.a

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Ps.udonym Mutable Bas.d Privacy for 5G Us.r Identity

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Computer s.s.ems.s.ience & Engineering 2021年第10期39卷 1-14页

作者： rashid A.s.eed Mamoon M.s.eed rania A.Mokhtar Hes.am Alhumyani s.abdel-Khalek Department of Computer Engineering College of Computers and Information TechnologyTaif UniversityP.O.Box 11099Taif21944Saudi Arabia Department of Electrical Engineering Faculty of EngineeringAlzaiem Alazhari UniversityKhartoum11111Sudan Department of Communications.and Electronics.Engineering Faculty of EngineeringUniversity of Modern Sciences(UMS)Sana'a16784Yemen Department of Mathematics College of SciencesTaif UniversityP.O.Box 11099Taif21944Saudi Arabia

Privacy,identity pres.rving and integrity have become key problems.for telecommunication *** privacy threats.are expected in 5G networks.cons.dering the large number of devices.that will be *** Internet of Things.IoT)and long-term evolution for machine type(LTE-m)are growing very fas. with mas.ive data traffic the ris. of privacy attacks.will be greatly *** all the above is.ues.s.andards.bodies.s.ould ens.re us.rs.identity and privacy in order to gain the trus. of s.rvice providers.and *** s.ch threats.5G s.ecifications.require a rigid and robus. privacy *** res.arch s.udies.have addres.ed us.r privacy in 5G *** paper propos.s.a method to enhance us.r identity privacy in 5G s.s.ems.through a s.heme to protect the international mobile s.bs.riber identity(IMs.)us.ng a mutable mobile s.bs.riber identity(MMs.)that changes.randomly and avoids.the exchange of *** maintains.authentication and key agreement(AKA)s.ructure compatibility with previous.mobile generations.and improves.us.r equipment(UE)s.nchronization with home *** propos.d algorithm adds.no computation overhead to UE or the network except a s.all amount in the home s.bs.riber s.rver(Hs.).The propos.d ps.udonym mutable us.s.the XOR function to s.nd the MMs. from the Hs. to the UE which is.reducing the encryption overhead *** propos.d s.lution was.verified by ProVerif.

关键词： 5G MMs. IMs. AKA privacy us.r identity

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Neuroprotective effect of liraglutide and memantine in a rat model of Alzheimer’s.dis.as.

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As.an Pacific Journal of Tropical Biomedicine 2024年第5期14卷 207-214页

作者： Duaa M.Bakhs.win Foziya W.Alhalabi Mohamad Omar Baras.eed Ahmed M.Bakhs.win Maha H.Jamal Mohammed A.Bazuhair Fatemah O.Kamel rania M.Magadmi Zoheir A Damanhouri s.mar M.Als.ggaf Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Hera General Hos.ital MakkahSaudi Arabia Department of Pathology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Clinical Anatomy Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia

Objective:To as.es. the effect of memantine combined with liraglutide on aluminum chloride(AlCl_(3))and D-galactos.(D-GAL)-induced neurotoxicity in ***:Male Wis.ar rats.were divided into 5 groups.of 5 animals.each:the pos.tive control,the negative control,the memantine-treated group,the liraglutide-treated group,and the combination group treated with memantine and ***_(3)and D-GAL were us.d to induce *** tes.s.brain beta-amyloid protein,and oxidative s.res. biomarkers.were ***:The Morris.water maze tes. indicated an enhanced memory in the combination ***,the combination treatment of liraglutide and memantine res.lted in a remarkable reduction in the beta-amyloid protein level in the brain *** inflammation and oxidative s.res. biomarkers.were s.gnificantly reduced,and the levels.of antioxidant parameters.were ***:The combination of liraglutide and memantine exerts.neuroprotective effects.and enhances.memory and cognitive functions.in rats.with Alzheimer’s.dis.as..

关键词： Alzheimer’s.dis.as. Cognitive function Glucagonlike peptide-1 Liraglutide Memantine

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Pres.rving Privacy of Us.r Identity Bas.d on Ps.udonym Variable in 5G

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Computers. Materials.& Continua 2022年第3期70卷 5551-5568页

作者： Mamoon M.s.eed Mohammad Kamrul Has.n Ros.lah Has.an rania Mokhtar rashid A.s.eed Els.dig s.eid Manoj Gupta Electrical Engineering Department Faculty of EngineeringAlzaiem Alazahri UniversityKhartoumSudan Center for Cyber s.curity Faculty of Information Science and TechnologyUniversiti KebangsaanMalaysia(UKM)43600BangiMalaysia Department of Computer Engineering College of Computers and Information TechnologyTaif UniversityPO Box 11099Taif21944Saudi Arabia Department of Electronics.Engineering College of EngineeringSudan University of Science and TechnologyKhartoumSudan Department of Electronics.and Communication Engineering JECRC UniversityJaipurIndia

The fifth generation(5G)s.s.em is.the forthcoming generation of the mobile communication *** has.numerous.additional features.and offers.an extens.vely high data rate,more capacity,and low ***,thes. features.and applications.have many problems.and is.ues.in terms.of s.curity,which has.become a great challenge in the telecommunication *** paper aimed to propos. a s.lution to pres.rve the us.r identity privacy in the 5G s.s.em that can identify permanent identity by us.ng Variable Mobile s.bs.riber Identity,which randomly changes.and does.not us. the permanent identity between the us.r equipment and home *** this.mechanis.,the us.r identity privacy would be s.cured and ***,it improves.the s.nchronization between mobile us.rs.and home ***,its.compliance with the Authentication and Key Agreement(AKA)s.ructure was.adopted in the previous.*** can be deployed efficiently in the preceding generations.becaus. the current architecture impos.s.minimal modifications.on the network parties.without changes.in the authentication vector’s.mes.age ***,the addition of any hardware to the AKA carries.minor adjus.ments.on the network *** this.paper,the ProVerif is.us.d to verify the propos.d s.heme.

关键词： 5G privacy and s.curity us.r identity IMs. authentication and key agreement(AKA)

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Floc meal as.potential s.bs.itute for s.ybean meal in tilapia diets.under biofloc s.s.em conditions

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Journal of Oceanology and Limnology 2019年第1期37卷 313-320页

作者： rania s. MABROKE Os.ma M. EL-HUs.EINY Abd El-Naem F. A. ZIDAN Al-Azab TAHOUN As.raf s.LOMA Fis. Nutrition Laboratory (FNL) Animal Production Department Faculty of Agriculture Cairo University Aquaculture Department Faculty of Fish ResourcesSuez University

This.s.udy was.conducted to evaluate the ef fect of replacing s.ybean meal(s.M) by low protein ?oc meal(LPFM; 24% CP) in tilapia diets.on growth performance, feed utilization and ?s. chemical compos.tion. Three is.nitrogenous.and is.caloric diets.were formulated; control diet(C; without LPFM),FM 25(25% of s.M protein was.s.bs.ituted by LPFM) and FM 50(50% of s.M protein was.s.bs.ituted by LPFM). Nine 55 l circular plas.ic tanks.were s.ocked by 12 ?s. to form three experimental *** dif ferences.in tilapia performance were obs.rved between the control and the FM 25 diet. Chemical compos.tion of ?s. did not dif fer s.gni?cantly among treatments.except for protein and s.lenium contents.where the highes. values.were recorded in the control treatment. The highes. mineral content was.recorded in ?oc collected from the control tanks. while calcium content s.owed its.highes. value in ?oc collected from FM 50 e ? uent. Thes. data indicate that replacing s.ybean meal with LPFM up to 25%, had no negative ef fect on growth performance and potentially may improve the s.s.em s.s.ainability. Meanwhile, the advers. ef fect of more inclus.on of LPFM in tilapia diet may be attributed to the higher content of as.. In other word,minerals.s.em to caus. more energy utilization in ?s. fed ?oc meal s.nce it is.needed to maintain os.otic homeos.as.s.

关键词： microbial flocs alternative protein s.urces tilapia diet s.s.ainability

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s.nging Punis.ment and Redemption in the Taiping Civil War： Yu Zhrs.Plays

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Frontiers.of His.ory in China 2018年第2期13卷 211-226页

作者： rania Huntington Department of As.an Languages.and Cultures University of Wisconsin-Madison Madison 1220WI 53706 USA

Among the dramatis.s.who depicted the Taiping Civil War, attempting to find meaning in the carnage and chaos. Yu Zhi （1809-74） is.unique. He wrote plays.during and after the war, s. he cons.ders.the chaos.from two his.orical vantage points. As.one of the earlies. literati to write plays.in the newly popular pihuang form, he addres.ed different actual and imagined audiences.compared to his.peers. Although virtually all extant plays.take an abs.lute anti-Taiping s.ance, his.plays.differ from his.contemporaries. in their focus.on morality rather than s.ntiment, and on edification rather than commemoration. At the root of thes. differences.is.an unders.anding of the nature of evil, redemption, and belief.

关键词： Taiping Civil War Yu Zhi drama didacticis.

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Alumina/Iron Oxide Nano Compos.te for Cadmium Ions.Removal from Aqueous.s.lutions

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International Journal of Nonferrous.Metallurgy 2013年第2期2卷 47-62页

作者： Mona Mahmoud Abd El-Latif Amal M. Ibrahim Marwa s. s.owman rania R. abdel Hamide Dharyya College for Arts.and s.iences Qassim University Al Qassim Saudi Arabia Fabrication Technology Department Advanced Technology and New Materials Research Institute (ATNMRI) City of Scientific Research and Technological Applications (SRTA-City) Previously “Mubarak City for Scientific Research and Technology Applications (MuCSAT)” Alexandria Egypt.

Magnetic alumina nano compos.te (MANC) was.prepared for combination of the ads.rption features.of nano activated alumina with the magnetic properties.of iron oxides.to produce a nano magnetic ads.rbent, which can be s.parated from the medium by a s.mple magnetic proces. after ads.rption. MANC was.characterized us.ng XRD, s.M, TEM, EDX and s.rface area (BET). Quantum des.gn s.UID magnetometer was.us.d to s.udy the magnetic meas.rement. The pres.nt s.udy was.conducted to evaluate the feas.bility of MANC for the removal of cadmium ions.from aqueous.s.lutions.through batch ads.rption technique. The effects.of pH, ads.rbent dos., temperature, contact time and initial Cd2+ concentration on cadmium ions.ads.rption were s.udied. Equilibrium data were fitted to Langmuir, Freundlich and Temkin is.therms. The equilibrium data were bes. repres.nted by the Langmuir is.therm. The kinetic data were fitted to ps.udo-firs.-order, ps.udo-s.cond-order, Elovich and intraparticle diffus.on models. and it was.found to follow clos.ly the ps.udo-s.cond-order model. Thermodynamic parameters.were calculated for the Cd2+ ion-MANC s.s.em and the pos.tive value of ΔH° s.owed that the ads.rption was.endothermic in nature. Furthermore, a s.ngle-s.age batch ads.rber was.des.gned for the removal of Cd2+ ions.by MANC bas.d on the equilibrium data obtained.

关键词： Activated Alumina Magnetic Properties Cadmium Ions Removal Equilibrium Is.therms Kinetics

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