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Mapping the global research landscape on insulin resistance: Visualization and bibliometric analysis

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World Journal of Diabetes 2022年第9期13卷 786-798页

作者： Sa’ed H Zyoud Muna Shakhshir Amer Koni Amani S Abushanab Moyad Shahwan Ammar Abdulrahman Jairoun rand Al Subu Adham Abu Taha Samah W Al-Jabi Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Information Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Division of Clinical Pharmacy Department of Hematology and Oncology PharmacyAn-Najah National University HospitalNablus 44839Palestine Department of Pharmacy Ajman UniversityAjman 346United Arab Emirates Centre of Medical and Bio Allied Health Sciences Research Ajman UniversityAjman 346United Arab Emirates Department of Health and Safety Dubai MunicipalityDubai 67United Arab Emirates Department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Biomedical Sciences College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Pathology An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Insulin resistance is a risk factor for metabolic syndromes and is associated with a wide variety of metabolic illnesses,including obesity,type 2 diabetes,and cardiovascular *** To investigate and map global insulin resistance *** A bibliometric methodology was applied to the literature retrieved from the Scopus database and Reference Citation Analysis(https://***)by using a validated search *** study period was limited from 2002 to *** indicators and mapping were *** A total of 26808 articles on the topic of insulin resistance were included in the Scopus *** articles included research articles(n=21918;81.76%),review articles(n=2641;9.85%),and letters(n=653;2.44%).During the study period,136 countries contributed to the research on insulin *** highest number of articles was from the United States(n=7360;27.45%),followed by China(n=3713;13.85%),Japan(n=1730,6.45%),Italy(n=1545;5.54%),and the United Kingdom(n=1484;5.54%).The retrieved articles identified two main research themes:“inflammatory mechanisms in the regulation of insulin resistance”and“mechanisms linking obesity to insulin resistance”.CONCLUSION Our data show that insulin resistance has steadily gained interest from researchers,as evidenced by the number of citations and yearly *** have grown significantly in the last decade,while low-income countries with greater burdens continue to produce fewer publications in this *** approach might assist researchers in choosing new research areas and recognizing research hotspots and *** the future,perhaps high-quality clinical evidence will be acquired.

关键词： Insulin resistance Research hotspots Scopus VOSviewer Bibliometric

Current global research landscape on COVID-19 and cancer: Bibliometric and visualization analysis

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World Journal of Clinical Oncology 2022年第10期13卷 835-847页

作者： Sa'ed H Zyoud Amer Koni Samah W Al-Jabi Riad Amer Muna Shakhshir rand Al Subu Husam Salameh Razan Odeh Sultan Musleh Faris Abushamma Adham Abu Taha Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine Hematology and Oncology Department An-Najah National University HospitalNablus 44839Palestine Department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of Urology An-Najah National University HospitalNablus 44839Palestine Department of Pathology An-Najah National University HospitalNablus 44839Palestine Department of Biomedical Sciences College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine

BACKGROUND Cancer is a severe public health issue that seriously jeopardizes global *** individuals with coronavirus disease 2019(COVID-19),cancer is considered an independent risk factor for severe illness and increased *** To identify research hotspots and prospects,we used bibliometrics to examine the global production of COVID-19 literature published in the field of *** Data on publication output were identified based on the Scopus database between January 1,2020,and June 21,*** study used VOSviewer to analyze collaboration networks among countries and assess the terms most often used in the titles and abstracts of retrieved publications to determine research hotspots linked to cancer and *** Impact Index Per Article for the top 10 high-cited papers collected from Reference Citation Analysis(RCA)are *** A total of 7015 publications were retrieved from the *** United States published the greatest number of articles(2025;28.87%),followed by Italy(964;13.74%),the United Kingdom(839;11.96%),and China(538;7.67%).The University of Texas MD Anderson Cancer Center(n=205,2.92%)ranked first,followed by the Memorial Sloan-Kettering Cancer Center(n=176,2.51%).The European Journal of Cancer(n=106,1.51%)ranked first,followed by the Frontiers in Oncology(n=104,1.48%),Cancers(n=102,1.45%),and Pediatric Blood and Cancer(n=95;1.35%).The hot topics were stratified into“cancer care management during the COVID-19 pandemic”;and“COVID-19 vaccines in cancer patients”.CONCLUSION This is the first bibliometric analysis to determine the present state and upcoming hot themes related to cancer and COVID-19 and vice versa using VOSviewer during the early stages of the *** emergence of hot themes related to cancer and COVID-19 may aid researchers in identifying new research areas in this field.

关键词： Bibliometric Scopus COVID-19 Cancer Coronavirus disease VOSviewer Reference Citation Analysis

国际MOOC研究热点与趋势——基于2013-2015年文献的Citespace可视化分析

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开放教育研究 2016年第1期22卷 90-99页

作者：石小岑李曼丽清华大学教育研究院北京100084

MOOC始发于2008年,之后这种课程模式不断创新和发展。2012年,随着Coursera、ed X和Uadacity三大平台的建立,MOOC在全球范围迅速兴起。平台提供者和国际媒体对其的报道吸引各界关注,不同学科背景的学者和社会工作者积极参与,各种类型的... 详细信息

MOOC始发于2008年,之后这种课程模式不断创新和发展。2012年,随着Coursera、ed X和Uadacity三大平台的建立,MOOC在全球范围迅速兴起。平台提供者和国际媒体对其的报道吸引各界关注,不同学科背景的学者和社会工作者积极参与,各种类型的文献急剧增长,2013年后的研究文献无论质量还是数量都超过前四年。对于MOOC国际文献的研究热点和趋势进行梳理,不仅有利于国内研究者了解国际MOOC发展动态,也可以为我国本土化的MOOC研究和发展提供借鉴和参考。本研究利用Citespace软件提供的知识图谱系统梳理2013-2015年MOOC研究文献,通过共引分析、聚类分析和共词分析等方法对MOOC领域的前沿热点、演化路径、研究内容进行分析后发现:研究热点集中于"个性化学习"和"课程完成率";研究内容主要包括学习过程研究、创新教学方法研究、课程设计与评估研究、MOOC背景下新技术研究、系统性政策研究;研究方法以学习分析和基于设计的研究为主。总体而言,研究主题仍比较零散,研究数据来源较为单一,多为单门或几门课程样本,且明显对课程设计和教师情况关注不够。

关键词： MOOC Citespace 知识图谱热点趋势

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郧县开展乡村医生两化教育的分析

中华医院管理杂志 2001年第2期17卷 118-119页

作者：李志国湖北省郧县中医院 442500

开展乡村医生的系统化和正规化教育，是贯彻国务院有关文件精神、实现我国农村２０００年人人享有卫生保健、提高农村医疗服务质量等的具体措施。为此，郧县的做法：①加强领导，确保两化教育的顺利开展；②建立培训基地，为两化教育提... 详细信息

开展乡村医生的系统化和正规化教育，是贯彻国务院有关文件精神、实现我国农村２０００年人人享有卫生保健、提高农村医疗服务质量等的具体措施。为此，郧县的做法：①加强领导，确保两化教育的顺利开展；②建立培训基地，为两化教育提供环境；①制定政策，营造两化教育氛围;④强化措施，调动乡村医生参与的积极性等。上述措施使全县３９６个行政村均建立了卫生室，平均每个村有乡村医生１．４７人，参与两化教育的达８６．ｌ％，新上岗的四个乡村医生全具备卫生中专学历。但乡村医生队伍建设中仍存一些亟待解决的问题。

关键词：乡村医生卫生室农村医疗服务卫生保健做法分析具体措施教育氛围中专培训基地

克氏针与镜下双Endobutton钢板治疗急性肩锁关节脱位

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中国矫形外科杂志 2017年第16期25卷 1463-1468页

作者：李小飞谢文瑾盛路新郭开今徐州医科大学附属连云港医院骨科连云港222002 徐州医科大学附属医院骨科江苏徐州221000

[目的]探讨克氏针与镜下双Endobutton钢板治疗急性肩锁关节脱位的临床效果。[方法]选择徐州医科大学附属连云港医院2012年6月~2016年12月收治的42例RockwoodⅢ~V型急性肩锁关节脱位患者。其中22例为肩关节镜下克氏针辅助双Endobutton钢... 详细信息

[目的]探讨克氏针与镜下双Endobutton钢板治疗急性肩锁关节脱位的临床效果。[方法]选择徐州医科大学附属连云港医院2012年6月~2016年12月收治的42例RockwoodⅢ~V型急性肩锁关节脱位患者。其中22例为肩关节镜下克氏针辅助双Endobutton钢板手术治疗,设为辅助组;另20例为肩关节镜下单独使用双Endobutton钢板手术治疗,设为单独组。术后1、3、6、9、12周,6、12个月定期门诊随访指导功能锻炼,此后每年随访一次。统计随访末期的疼痛评分(VAS评分)、Constant-Murley评分以及ASES评分、喙锁距离及肩锁距离。[结果]42例患者均获得随访,随访时间平均16.4个月(3~36个月)。辅助组手术时长较单独组长,但辅助组患者术后恢复工作时间较单独组短,Constant-Murley评分、ASES评分较单独组高,且辅助组患者的喙锁距离及肩锁距离较单独组短(P<0.05)。[结论]肩关节镜下克氏针结合双Endobutton钢板治疗急性肩锁关节脱位疗效较单独双Endobutton钢板治疗效果满意。

关键词：肩锁关节脱位肩关节镜克氏针 Endobutton钢板

分散固相萃取结合HPLC-MS/MS检测鸡蛋中16种全氟化合物

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分析测试学报 2014年第10期33卷 1109-1115页

作者：李静张鸿柴之芳沈金灿杨波深圳大学化学与化工学院广东深圳518060 深圳大学物理科学与技术学院广东深圳518060 中国科学院高能物理研究所北京100049 深圳出入境检验检疫局食品检验检疫技术中心广东深圳518045

建立了分散固相萃取净化结合 HPLC -MS/MS 测定鸡蛋中16种全氟化合物（ Perfluorinated com-pounds，PFCs）的方法。样品经乙腈40℃下超声萃取，氮吹浓缩，石墨化碳黑分散萃取净化后，采用HPLC-MS/MS进行测定，基质曲线-内标法定量。结... 详细信息

建立了分散固相萃取净化结合 HPLC -MS/MS 测定鸡蛋中16种全氟化合物（ Perfluorinated com-pounds，PFCs）的方法。样品经乙腈40℃下超声萃取，氮吹浓缩，石墨化碳黑分散萃取净化后，采用HPLC-MS/MS进行测定，基质曲线-内标法定量。结果显示，16种PFCs在0.50-10.0μg/L浓度范围内呈良好线性，相关系数（ r）为0.9962-0.9999，检出限为0.001-0.093μg/kg，定量下限为0.003-0.310μg/kg。在0.5，1.0，2.0μg/kg 3个加标浓度水平下，16种PFCs的加标回收率为79％-125％，相对标准偏差（ RSDs， n=6）为0.26％-14％。该方法具有净化效果好、定量准确、灵敏度高的特点，适用于鸡蛋样品中16种常见全氟化合物的快速确认和准确定量。

关键词：全氟化合物鸡蛋高效液相色谱-串联质谱分散固相萃取石墨化碳黑

冷冻血液性心脏停搏液与冷冻晶体心脏停搏液的比较:1440例行冠脉搭桥术患者的前瞻性随机研究

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世界核心医学期刊文摘（心脏病学分册） 2005年第4期1卷 60-61页

作者： vrum E. Tangen G. T.ll.fsrud S. 孟欣 Oslo Heart Center Oslo Norway Dr.

Objectives A large number of experimental studies have indicated that blood ca rdioplegia might be superior to crystalloid cardioplegia for myocardial protecti on during ischemic arrest. However, no prospectively randomized studies of large patient series have been undertaken to prove potential differ ences in clinical course. Methods Over a 52-month period, all patients undergoi ng on-pump coronary artery bypass operated on by 2 surgeons were prospectively randomized to receive either cold crystalloid cardioplegia(group C) or cold bloo d cardioplegia(group B) during aortic crossclamping. Results Altogether, 1440 pa tients aged 37 to 89 years (median, 66 years) entered the study(group C, n=719; group B, n=721). The groups were comparable in all major demographic, preoperati ve, and operative variables. The clinical course turned out to be nearly identic al for both groups. No statistically significant differences were seen concernin g spontaneous sinus rhythm after aortic declamping, use of inotropic drugs or in tra-aortic balloon pumping, postoperative ventilatory support, bleeding and rat e of allogeneic blood transfusions, perioperative myocardial infarction, episode s of atrial fibrillation, stroke or minor neurologic dysfunction, renal function , infections, physical rehabilitation, or mortality. Also, in subgroups of patie nts at higher operative risk(female sex, age >70 years, unstable angina, diabete s, emergency operation, ejection fraction 50 minutes , andEuroSCORE >4), no statistically significant differences could be demonstrat ed between the groups. Conclusions There were no significant differences whether myocardial protection was performed with cold blood cardioplegia or cold crysta lloid cardioplegia during aortic crossclamping in patients undergoing coronary a rtery bypass grafting. The extra costs related to blood cardioplegia might be sa ved. Copyright.

关键词：晶体心脏停搏液冠脉搭桥术血液性随机研究松开主动脉钳夹手术危险主动脉横断无显著性差异临床过程外科医生

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基于DWT具有篡改定位的半脆弱水印算法

信息安全研究 2019年第2期5卷 162-167页

作者：李子臣宋培非丁海洋北京印刷学院信息工程学院北京102600

半脆弱水印因为在多媒体内容认证方面的重要作用而受到人们密切的关注.为了能够区分偶然攻击与恶意篡改,半脆弱水印需要对一般的内容保护图像操作有一定的鲁棒性.根据图像相邻小波高频系数之间的大小关系在JPEG压缩之后大多数没有发生... 详细信息

半脆弱水印因为在多媒体内容认证方面的重要作用而受到人们密切的关注.为了能够区分偶然攻击与恶意篡改,半脆弱水印需要对一般的内容保护图像操作有一定的鲁棒性.根据图像相邻小波高频系数之间的大小关系在JPEG压缩之后大多数没有发生变化这一事实,提出了一种新的基于DWT变换的具有篡改定位的半脆弱水印算法,该算法主要思想是根据图像相邻小波高频系数之间的大小关系来嵌入水印.仿真实验结果表明:该算法嵌入容量大,有很好的抗JPEG压缩性能,同时也能对恶意篡改精确定位.

关键词：半脆弱水印恶意篡改 JPEG压缩小波系数高频系数

Pistillate Flower Development and Stigma Receptivity of Euphorbia pulcherrima

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Agricultural Science & Technology 2014年第10期15卷 1671-1675页

作者：李畅苏家乐刘晓青陈尚平何丽斯江苏省农业科学院园艺研究所/江苏省高效园艺作物遗传改良重点实验室江苏南京210014

Objective] This study aimed to investigate the relationship between pistil-late flower developmental morphology and stigma receptivity in Euphorbia pulcherri-ma. [Method] One-year-old adult plants of E. pulcherrima cultivar ‘Mil enium’ were used as experimental materials to analyze pistil ate flower development process by macroscopic and scanning electron microscope （SEM） observation. Stigma receptivity was detected with benzidine-hydrogen peroxide method and in vivo pol en germina-tion method. [Result] The pistil ate flower development process of E. pulcherrima was consisted of columnar stigma phase, stigma lobe slightly opening phase, Y-shape stigma lobe phase, inverse V-shaped stigma lobe phase and stigma curling phase. Pistil ate flower development and stigma receptivity of E. pulcherrima exhibit-ed certain correlation. The stigma receptive period lasted from stigma lobe slightly opening phase to inverse V-shaped stigma lobe phase; inverse V-shaped stigma lobe phase was appropriate for pol ination, lasting for 3-5 d, with V-shaped stigma lobe and a large amount of exudates on stigma surface according to SEM obser-vation. Stigma receptivity of E. pulcherrima detected with benzidine-hydrogen perox-ide method was consistent with that detected in vivo pol en germination method. [Conclusion] ln breeding practice, the optimal pol ination period of E. pulcherrima can be determined based on the developmental morphology of pistil ate flower.

关键词： Euphorbia pulcherrima Pistil ate flower Stigma Morphological development Receptivity