检索结果-南通市图书馆

Helium Plasma Effects on Polymer Surfaces:from Plasma Parameters and Surface Properties towards Bioengineering Applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第8期42卷 1156-1166页

作者： Andrei Vasile Nastuta Maria Butnaru Byron Cheatham ramona Huzum Vasile Tiron Ionut Topala Physics and Biophysics Education Research Laboratory(P&B-EduResLab) Biomedical Science DepartmentFaculty of Medical Bioengineering‘Grigore T.Popa’University of Medicine and Pharmacy IasiM.Kogalniceanu 9-13Iasi 700454Romania Faculty of Medical Bioengineering ‘Grigore T.Popa’University of Medicine and Pharmacy IasiM.Kogalniceanu 9-13Iasi 700454Romania Cytoviva Inc.570 Devall Drive Suite 301Auburn 36832ALUSA Integrated Center of Environmental Science Studies in the North-Eastern Development Region(CERNESIM) Department of Exact and Natural SciencesInstitute of Interdisciplinary Research‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania Research Center on Advanced Materials and Technologies(RAMTECH) Department of Exact and Natural SciencesInstitute of Interdisciplinary Research‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania Iasi Plasma Advanced Research Center(IPARC) Faculty of Physics‘Alexandru Ioan Cuza’University of IasiBlvd.Carol I no.11Iasi 700506Romania

Plasma treatment is necessary to optimize the performance of biomaterial *** enhances and regulates the performance of biomaterial su rfaces,creating an effective interface with the human *** treatments have the ability to modify the chemical com position and physical structu re of a surface while leaving its properties *** possess the ability to modify material su rfaces,eliminate contaminants,conduct investigations on cancer therapy,and facilitate wound *** subject of study in question involves the integration of plasma science and technology with biology and *** a helium plasma jet source,applying up to 18 kV,with an average power of 10 W,polymer foils were treated for 60 *** treatment has the ability to alter the chemical composition and physical structure of a su rface while maintaining its *** investigation involved the application of helium plasma at atmospheric pressure to polyamide 6 and polyethylene terephthalate *** inquiry involves monitoring and assessing the plasma source and polymer materials,as well as analyzing the impacts of plasma *** the mean power of the discharge aids in assessing the economic efficacy of the plasma *** discharge in helium at atmospheric pressure has beneficial effects in technology,where it increases the surface free energy of polymer *** biomedicine,it is used to investigate cytotoxicity and cell survival,particularly in direct blood exposure situations that can expedite *** the specific parameters that influence the plasma source in the desired manner for the intended application is of utmost im portance.

关键词： Atmopheric pressure plasmas Plasma-polymer interaction Plasma Medicine Plasma diagnosis Polymer characterization

Efficient scar-free knock-ins of several kilobases in plants by engineered CRISPR-Cas endonucleases

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2024年第5期17卷 824-837页

作者： Tom Schreiber Anja Prange Petra Schafer Thomas Iwen ramona Grutzner Sylvestre Marillonnet Aurelie Lepage Marie Javelle Wyatt Paul Alain Tissier Department of Cell and Metabolic Biology Leibniz Institute of Plant BiochemistryWeinberg 306120 Halle(Saale)Germany Limagrain Centre de RechercheRoute d’EnnezatCS 9012663720 ChappesFrance

In plants and mammals,non-homologous end-joining is the dominant pathway to repair DNA doublestrand breaks,making it challenging to generate knock-in *** this study,we identified two groups of exonucleases from the herpes virus and the bacteriophage T7 families that conferred an up to 38-fold increase in homology-directed repair frequencies when fused to Cas9/Cas12a in a tobacco mosaic virus-based transient assay in Nicotiana *** achieved precise and scar-free insertion of several kilobases of DNA both in transient and stable transformation *** Arabidopsis thaliana,fusion of Cas9 to a herpes virus family exonuclease led to 10-fold higher frequencies of knock-ins in the first generation of *** addition,we demonstrated stable and heritable knock-ins in wheat in 1%of the primary *** together,our results open perspectives for the routine production of heritable knock-in and gene replacement events in plants.

关键词： homology-directed repair knockin gene replacement CRISPR-Cas 50 exonuclease plants

The Link between Psychomotor Disorders and Physical Therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Medical Psychology 2024年第1期13卷 1-10页

作者： ramona Delia Arsani Marius Stoica National University of Physical Education and Sports Bucharest Romania

The evolution of the individual in ontogenesis has been studied throughout life and on all sides of development. Studies in the field based on medical rehability performed by a full team such as doctors, physiotherapists and psychologists and not only have shown that the link between the patient’s psychological state and exercise are factors in full dependence and any imbalance can trigger irreparable effects. Psychology is the science that studies the laws of formation, development, functioning and deficiencies related to psychism;it includes a series of fundamental concepts that include: psychic processes, psychic phenomena, psychic attributes, psychic states or psychic activities. Psychic phenomena are the component elements of psychism. In a sense, the psychic phenomena are manifested by external facts, by our behavior, by the motor actions started, by gestures or verbal actions;in the other sense, psychic phenomena are manifested by inner deeds, as the form of ideas, images, feelings, and desires. The motor acts without psychism would be only simple automatisms, without human specifications of adaptation, while the psychism without motor acts would be deprived of the fundamentals of formation and functioning as well as of its production mechanisms. Objective: The objective of this study is to highlight the causal problems of delayed medical recovery in relation to the psychological and emotional factors. This desktop review aims to identify psychoemotional disorders in the case of subjects with operated lumbar disc herniation and aims to adapt a specialized physiotherapeutic protocol by adapting to CIF. The result of this study will be found in the percentage of socio-professional reintegration of the subjects with operated lumbar disc herniation and implicitly the increase in the quality of life. Conclusions: 1) For an effective functional recovery, a psycho-emotional balance is needed;2) A positive attitude actively influences medical rehabilitation;3) Regain

关键词： Hyperkinesia Hypokinesia Tics Body Schema Disorders Apraxia

Stretching on chromosomes sheds light on their architecture

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第9期7卷 3179-3180页

作者： ramona Juhlen Wolfram Antonin Institute of Biochemistry and Molecular Cell Biology Medical SchoolRWTH Aachen UniversityAachenGermany

In a recent study published in Nature,Meijering et al.1employ elegant optical trapping and manipulation experiments of mitotic chromosomes to gain insights into their biomechanical *** mitosis,chromosomes rearrange in... 详细信息

关键词： shaped trapping insight

Hybrid Additive Manufacturing of Forming Tools

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Automotive Innovation 2023年第3期6卷 311-323页

作者： Hamed Dardaei Joghan ramona Holker‑Jager Anna Komodromos A.Erman Tekkaya Institute of Forming Technology and Lightweight Components(IUL) TU Dortmund UniversityBaroper Stra.e 30344227 DortmundGermany

Additive manufacturing(AM)is widely used in the automotive industry and has been expanded to include aerospace,marine,and *** flexibility and the possibility of manufacturing complex parts in AM motivate the integration of additive manu-facturing with classical forming technologies,which can improve tooling concepts and reduce *** study presents three applications of this ***,the possibility of successful utilization of selective laser melting for manufacturing extrusion tools with complex cooling channels and paths for thermocouples is reported,leading to significantly reduced inner die temperatures during the extrusion ***,sheet lamination is integrated with laser metal deposition(LMD)to manufacture deep-drawing *** results are achieved in reducing the stair step effect,which is the main challenge in sheet lamination,by LMD and following post-processing such as milling,ball burnishing,and laser *** new manufacturing route shows that LMD can economically and efficiently reduce the stair step effect and omit the hardening step from the conventional manufacturing process ***,LMD is used to manufacture a hot stamping punch with improved surface roughness by ball burnishing and near-surface complex cooling *** experimental results show that the manufactured punch has lower temperatures during hot stamping compared with the conventionally manufactured *** study shows the successful integration of AM processes with classical forming processes.

关键词： Additive manufacturing Laser metal deposition Selective laser melting Rapid tooling Forming tool Layer laminated manufacturing

Lipid peroxidation: Its effects on the formulation and use of pharmaceutical emulsions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2017年第5期12卷 401-411页

作者： ramona Khanum Haema Thevanayagam School of Postgraduate Studies International Medical University (IMU)

Pharmaceutical delivery systems are developed to improve the physicochemical properties of therapeutic compounds. Emulsions are one of these drug delivering systems formulated using water, oils and lipids as main ingredients. Extensive data are usually generated on the physical and chemical characteristics of these oil-in-water and lipid emulsions. However, the oxidative tendency of emulsions is often overlooked. Oxidation impacts the overall quality and safety of these pharmaceutical emulsions. Additionally, introducing oxidatively unstable emulsions into biological systems further promotes oxidation in situ. Products of these reactions then continue to pose serious harm to cells and fuel other physiological oxidation reactions. Consequently, the increase of oxidation products leads to oxidative damage to biological systems. Thus, emulsions with lower lipid peroxidation are more stable and will reduce the negative effects of oxidation in situ. Preventive measures during the formulation of emulsions are important. Many naturally occurring and cost effective substances possess low oxidation tendencies and confer oxidative protection when used in emulsions. Additionally,certain preparatory methods should be employed to reduce or better control lipid ***, emulsions must be evaluated for their oxidation susceptibility using the various techniques available. Careful attention to the preparation of emulsions and assessment of their oxidative stability will help produce safer emulsions without compromising efficacy.

关键词： Drug delivery Emulsions Lipids Peroxidation Oxidative stress

Intrinsic charm production of doubly charmed baryons:Collider vs. fixed-target

在线全文

学校读者我要写书评

暂无评论

Science China(Physics,Mechanics & Astronomy) 2020年第2期63卷 29-31页

作者： ramona Vogt Stanley J.Brodsky 无 Nuclear and Chemical Sciences Division Lawrence Livermore National LaboratoryLivermoreCA 94551USA Department of Physics University of CaliforniaDavisCA 95616USA Stanford Linear Accelerator Center Stanford UniversityStanfordCA 94309USA

The LHCb Collaboration has measured the doubly charmed baryon,■^++cc(ucc),through two different decay channels[1,2]in p+p collisions at center-of-mass energies of 7,8 and 13 *** they have performed similar searches for the doubly charmed baryon ■^+cc(dcc),it has not yet been observed by LHCb[3].However,the fixed-target experiment,SELEX,at Fermilab,reported the observation of the ■^+cc in two different decay channels with a 600 GeV charged hyperon beam[4,5].The beam was composed of an admixture of π^±,p,p components as well as the Σ^- *** discussion has arisen over the fact that the fixed-target observations have not been easily reproduced by the collider experiments at higher energies,where one might have expected the production rates to be much higher due to the orders of magnitude increase in the center of mass energy with LHCb.

关键词： doubly fixed decay

Functional Rehabilitation of Disc Herniation Treated with Combined Therapy

在线全文

学校读者我要写书评

暂无评论

International Journal of Clinical Medicine 2023年第11期14卷 472-486页

作者： ramona Delia Arsani Marius Stoica Carmen Gherghel National University of Physical Education and Sports Bucharest Romania

Current researches reveal that the number of cases diagnosed with operated lumbar disc herniation is growing rapidly, which should draw an increased attention to the treatment used. The objective of this study is to perform a comparative analysis between the application of a classical physical-kinetic program and the application of a combined kinetic program. This research will be conducted on 20 subjects with ages, between 40 - 50 years old, in INEMRCM Bucharest, for 14 days - 1 hour a day. Each subject underwent an invasive surgery for lumbar disc herniation on the L5-S1 vertebrae. During the research, the 2 patients will be given a physical-kinetic program, adapted to the pathology of the operated lumbar disc herniation. The purpose of this research is to check the efficiency of each kinetic program. Furthermore, through the muscular and articular evaluation made in the initial phase and the final phase, it will be possible to discuss the comparative evolution of the established kinetic program and the functional gain obtained. In conclusion, the research shows that mechanized therapy results in faster functional rehabilitation and physical exercise substantially improves quality of life.

关键词： Lumbar Disc Herniation Rehabilitation Physical Therapy

Production of succinic acid in basket and mobile bed bioreactors-Comparative analysis of substrate mass transfer aspects

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2016年第4期24卷 513-520页

作者： Anca-Irina Galaction Dan Cascaval ramona-Mihaela Matran Alexandra Tucaliuc "Grigore T. Popa" University of Medicine and Pharmacy of Iasi Faculty of Medical Bioengineering Dept. of Biomedical Science M. Kogalniceanu 9-13 700454 Iasi Romania "Gheorghe Asachi" Technical University of Iasi Faculty of Chemical Engineering and Environmental Protection. Dept. of Biochemical Engineering D. Mangeron 73 700050 Iasi Romania

The glucose mass transfer in the biosynthesis of succinic acid with immobilized Actinobacillus succinogenes cells has been comparatively analyzed for a bioreactor with mobile bed vs. a stationary basket bioreactor. The process has been considered to occur under substrate and product inhibitory effects. The results indicated that the bioreactor with mobile bed is more efficient for biocatalyst particles with a diameter over 3 mm, while the basket bioreactor is more efficient for smaller biocatalyst particles and basket bed thickness below 5 mm. The performances of both configurations of immobilized A. succinogenes cell beds were found to be superior to the column packed bed bioreactor.

关键词：填充床生物反应器琥珀酸移动床传质基质生产生物催化剂生物合成