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An animal cell culture: Advance technology for modern research

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Advances in Bioscience and Biotechnology 2012年第3期3卷 219-226页

作者： rajeev nema Sarita Khare Center for Microbiology & Bio-Technology Research and Training Bhopal India Department of Zoology and Biotechnology Sarojini Naidu Government Girls Post Graduate (Autonomous) College Bhopal India

At the present time animal cell culture is more significant and multifarious application tool for current research streams. A lot of field assorted from animal cell culture such: stem cell biology, IVF technology, cancer cell biology, monoclonal antibody production, recombinant protein production, gene therapy, vaccine manufacturing, novel drug selection and improvement. In this review conclude animal cell culture as well as its

关键词： Animal Cell Culture

Naturally Derived Formulations and Prospects towards Cancer

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Health 2019年第7期11卷 971-997页

作者： Neha Masarkar Sukhes Mukherjee Sudhir K. Goel rajeev nema All India Institute of Medical Science (AIIMS) Bhopal (Madhya Pradesh) India

Traditional Medicine (TM) and their secondary metabolites are being increasingly recognized as useful complementary treatments toward the cancer. A large number of clinical studies have reported and proven concern of cancer patients. Here we have also reported recent studies on the biochemical and cellular mechanisms of Traditional Medicine (TM). Nowadays, Chemotherapy and surgery are standard methods for treatment of cancer, but still it’s not been fully successful. Some progress has been made in cancer diagnosis and treatment, but high incidence rate of cancer and low survival rate of patient are still being reported worldwide. Since ancient times, a number of traditional medicines known as Ayurveda, Siddha, Unani, Iranian, Chinese, Korean, acupuncture, Muti, Ifa, and African medicine are widely used for therapeutic purposes and are becoming popular as Traditional Medicine (TM). It has been reported that plants synthesize plethora of “secondary metabolites” or “phytochemicals”, proven to possess anti-mutagenic and anti-cancer properties in many research studies. There are many possibilities for further organized research for screening of medicinal plants for their potential and efficacy against chronic diseases such as a cancer and other inflammatory diseases. Therefore, researcher’s interest should be in identification and standardization of new anti-cancer drug with low side effects and greater efficacy, that is easily acceptable in medical community and which may overcome the challenges in present and future cancer therapy. This review explores therapeutic value of certain bio-active principals of plant which could serve as potential pharmacologically active drug for treatment of cancer in future.

关键词： Bio-Active Principles Cancer Chemotherapy Phytochemicals Secondary Metabolites

Natural Products Potential and Scope for Modern Cancer Research

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American Journal of Plant Sciences 2013年第6期4卷 1270-1277页

作者： rajeev nema Sarita Khare Parul Jain Alka Pradhan Abhishek Gupta Dharmendra Singh Center for Microbiology & Bio-Technology Research and Training Institute Bhopal Bhopal India Government of Motilal Vigyan Mahavidyalaya Bhopal India. S.V. Polytechnic College Bhopal India Sarojini Naidu Government Girls Post Graduate (Autonomous) College Bhopal India Sarojini Naidu Government Girls Post Graduate (Autonomous) College Bhopal India

In the present time Natural products are considered to be symbols of protection in comparison to the synthetic product that are regarded as unsafe to human life and environment. Although a large number of synthetic drugs are being added to the world of present pharmacopoeia, but still no system of medicine in the world has been able to solve all the health problems, which include diseases like Cancer. Therefore the search for innovative therapeutic constituents from plants is genuine and urgent. In India, there is an ocean of knowledge about medicinal plants and rich medicinal flora, but still only a few pearls have been searched as therapeutic agents. There are large numbers of original plants left which have not been investigated thoroughly from modern scientific view or their healing values have not been known. Thus there is an insistent need for systematic phytochemical examination of those plants which have not been investigated scientifically. More research can be done to investigate the unknown and unexplored potential of plants. Further analysis of plants (active compounds) can be carried out by way of making use of different analytical methods such as HPTLC, HPLC, NMR and UV spectrophotometer analysis or computer based drug designing.

关键词： Medicinal Plant Natural Product Cancer Biology

R21 vaccine:A ray of hope for malaria elimination

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Asian Pacific Journal of Tropical Medicine 2023年第6期16卷 243-244页

作者： Nitika Nitika Shrikant nema Praveen Kumar Bharti ICMR-National Institute of Malaria Research Sector 8DwarkaNew DelhiIndia

The steady decline in malaria cases and deaths in recent years is a step ahead toward elimination;however,an increasing number of reports of antimalarial and insecticide resistance highlight the importance of having newer approaches to achieve the goal in the stipulated time ***,having an effective and durable malaria vaccine is extremely crucial,which can complement the tools currently in *** the malaria vaccine development efforts initiated in the 1910’s with the first attempts to develop a malaria vaccine involved inoculating humans with live,attenuated strains of the malaria parasite but the efforts have been intensified over the previous decade,resulting in several significant developments.

关键词： malaria vaccine elimination

Malaria slide bank plays a crucial role in achieving and sustaining malaria elimination in India

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Asian Pacific Journal of Tropical Medicine 2023年第10期16卷 431-433页

作者： Shrikant nema Nitika Nitika Anup R Anvikar Praveen K Bharti ICMR-National Institute of Malaria Research Sector 8Dwarka 110077New DelhiIndia

India's healthcare system continues to place the highest priority on the fight against malaria[1].Malaria elimination program has received considerable attention from both the public and private sectors,resulting in a significant drop in malaria cases[2].In 2022,a total of 176000 million cases of malaria were reported in India,in which Plasmodium(P.)falciparum has contributed 57.0%and 42.3%were *** cases and limited cases of *** and ***.

关键词： malaria Malaria elimination

Comparative study of therapeutic effects of PPI and H2RA on ulcers during continuous aspirin therapy

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World Journal of Gastroenterology 2010年第42期16卷 5342-5346页

作者： Hiroaki nema Mototsugu Kato Department of Internal Medicine Teishinkai HospitalNorth 44East 8Higashi-kuSapporoHokkaido 007-0844Japan Division of Endoscopy Hokkaido University HospitalNorth 14West 5Kita-kuSapporoHokkaido 060-8468Japan

AIM:To compare the therapeutic effects of proton pump inhibitors(PPI) and histamine 2 receptor antagonists(H2RA) on gastroduodenal ulcers under continuous use of low-dose ***:Sixty patients who had a gastroduodenal ulcer on screening endoscopy but required continuous use of low-dose aspirin were randomly assigned to receive PPI(lansoprazole 30 mg,n = 30) or H2RA(famotidine 40 mg or if famotidine had been administered before assignment,ranitidine 300 mg,n = 30).The therapeutic effects were evaluated by endoscopy after 8-wk *** presence or absence of Helicobacter pylori(***) was determined by urea breath test before *** symptoms were compared with the gastrointestinal symptom rating scale(GSRS) questionnaire before and after ***:Twenty-six patients in the PPI group and 26 patients in the H2RA group,excluding dropouts,were *** were no significant differences in median age,sex,underlying disease,smoking status,*** infection,prevalence of ulcers before treatment,and lesion site between the two *** therapeutic effects were endoscopically evaluated as healed in 23 patients(88.5%) and not healed in 3 patients in the PPI group and as healed in 22 patients(84.6%) and not healed in 4 patients in the H2RA *** symptoms before treatment were uncommon in both groups;the GSRS scores were not significantly reduced after treatment as compared with before ***:The healing rate of gastroduodenal ulcers during continuous use of low-dose aspirin was greater than 80% in both the PPI group and the H2RA group,with no significant difference between the two groups.

关键词： Low-dose aspirin Proton pump inhibitors Histamine 2 receptor antagonists Gastric ulcer

Thermodynamics of the Bardeen Regular Black Hole

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Chinese Physics Letters 2012年第7期29卷 25-28页

作者： M.Akbar nema Salem S.A.Hussein Effat University Jeddah 21478Kingdom of Saudi Arabia

We deal with the thermodynamic properties of the Bardeen regular black hole with reference to their respective *** is argued here that the expression of the heat capacity at horizons is positive in one parameter region and negative in the other,and between them the heat capacity diverges where the black hole undergoes the second-order phase transition.

关键词： transition Regular Thermodynamics

Are Environmental Vanguard Firms More Proactive Towards Environmental Conservation?An Empirical Study of Power Sector Firms in India

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Journal of Environmental & Earth Sciences 2019年第2期1卷 31-41页

作者： Arun Kumar Vishwakarma Arvind K nema National Institute of Industrial Engineering MumbaiIndia Indian Institute of Technology Delhi New DelhiIndia

Environmental protection is a crucial issue for environmentalists and *** every stakeholder in the industrial production process of a product is concerned about the detrimental effects on the environment due to *** environmental regulations are in place,some firms across diverse industrial sectors are considered as the environmental vanguard,i.e.,leaders in environmental *** being environmental vanguard result in environmental proactivity?This paper,through an empirical study of Indian power sector firms,studies the environmental proactivity of the firms who are known to be leaders in the adoption of environmental protection norms.A questionnaire-based survey method is used to analyse the responses *** study uses 280 responses for the analysis of the *** hypotheses are proposed and tested statistically through Structural Equation Modelling(SEM).The statistical analysis reveals that the firms who are environmental vanguard are more proactive towards environmental *** findings of the study can be useful for the policymakers and environmental managers in the formulation of policies which can be considered as a benchmark for the firms for the protection of the environment.

关键词： Proactive environmental strategies Environmental vanguard Statistical analysis Power sector Structural equation modelling

Does age, time since injury and meniscal injury affect short term functional outcomes in arthroscopic single bundle anterior cruciate ligament reconstruction？

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Chinese Journal of Traumatology 2018年第1期21卷 50-53页

作者： Udit Kumar Biswal Gopisankar Balaji Sandeep nema Jagdish Menon Dilip Kumar Patro Department of Orthopaedics Jawaharlal Institute of Postgraduate Medical Education and Research Pondicherry 605006 India

PurposeWe 进行了这研究相关短术语在前面的十字形的系带(ACL ) 以后的临床的结果有病人年龄的重建，后来预定损害和经历了在 2013 年 10 月和 2015 年 2 月之间的 ACL 重建的 43 个病人的联系 meniscal *** 总数为学习被拿。外科手术... 详细信息

PurposeWe 进行了这研究相关短术语在前面的十字形的系带(ACL ) 以后的临床的结果有病人年龄的重建，后来预定损害和经历了在 2013 年 10 月和 2015 年 2 月之间的 ACL 重建的 43 个病人的联系 meniscal *** 总数为学习被拿。外科手术前的人口统计的数据，临床的分数(Lysholm， IKDC ) 为每个病人被记录。自从损害和联系 meniscal，损害被记录的时间。然后，一种标准化外科的技术被用于每种接枝类型。他们被跟随在上面为分数是的 6 个月和 Lysholm 和 IKDC， ***， 33 个病人在这研究的结束完成了 6 月后续。24 个病人(72.7%) 在 18-30 年的年龄组。九个病人属于年龄组 30-50 年(27.3%) 。为在在二个年龄组之间的 Lysholm 分数的差别的 p 价值不是重要的(0.339 ) 。为在在二个年龄组之间的 IKDC 分数的差别的 p 价值不是重要任何一个(0.138 ) 。吝啬的 Lysholm 分数是 93.86 吗？？

关键词：十字形损害时间术语外科手术年龄组人口统计统计意义