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Aging is associated with cardiac autonomic nerve fiber depletion and reduced cardiac and circulating BDNF levels

Journal of Geriatric Cardiology 2021年第7期18卷 549-559页

作者： Andrea Elia Alessandro Cannavo Giuseppina Gambino Maria Cimini Nicola Ferrara raj kishore Nazareno Paolocci Giuseppe Rengo Department of Translational Medical Sciences Federico Ⅱ University of Naples Italy Istituti Clinici Scientifici ICS-Maugeri Telese Terme(BN)Italy Center for Translational Medicine Department of PharmacologyLewis Katz School of MedicineTemple UniversityPhiladelphiaPennsylvaniaUSA Division of Cardiology Johns Hopkins University Medical InstitutionsBaltimoreMDUSA Department of Biomedical Sciences University of PadovaItaly

Background Aging is a multifactorial process associated with an impairment of autonomic nervous system(ANS)*** ANS remodeling includes upregulation of expression of circulating catecholamines and depletion of cardiac autonomic nerve fibers,and it is responsible,in part,for the increased susceptibility to cardiac diseases observed in elderly *** factors,such as brain-derived neurotrophic factor(BDNF)and nerve growth factor(NGF),are involved in synaptogenesis and neurite outgrowth processes,supporting neuronal cell differentiation and ***,whether and how these factors and their downstream signaling are involved in cardiac aging remains ***,we tested whether,in the aged heart,the overall extent of autonomic fibers is reduced,owing to lower production of trophic factors such as BDNF and *** In vivo,we used young(age:3 months;n=10)and old(age:24 months;n=11)male Fisher rats,whereas,we used human neuroblastoma(sh-SY5 Y)cells in *** Compared to the young rats,old rats displayed a marked reduction in the overall ANS fiber density,affecting both sympathetic and cholinergic compartments,as indicated by dopamineβ-hydroxylase(dβh)and vesicular acetylcholine transporter(Va Ch T)immunohistochemical *** addition,a marked downregulation of GAP-43 and BDNF protein was observed in the left ventricular lysates of old rats compared to those of young ***,we did not find any significant difference in cardiac NGF levels between the young and old *** further explore the impact of aging on ANS fibers,we treated sh-SY5 Y cells in vitro with serum obtained from young and old *** from both groups induced a remarkable increase in neuronal sprouting,as evidenced by a crystal violet ***,this effect was blunted in cells cultured with old rat serum and was accompanied by a marked reduction in GAP-43 and BDNF protein *** Our data indicate that physiological aging i

关键词： cardiac depletion fibers

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Effect of various ratios of poly(3-hexylthiophene)with polyvinyl alcohol gel-polymer electrolytes in flexible sodium-ion batteries using Samanea saman tree-leaf-derived carbon quantum dots decorated with SnO_(2)and NaVO_(3)

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Clean Energy 2022年第1期6卷 226-237页

作者： Baskar Thangaraj Nutthapon Wongyao Pravin raj Solomon Wachira Chaiworn Surawut Chuangchote Werasak Surareungchai Pilot Plant Development and Training Institute King Mongkut’s University of Technology ThonburiBangkhuntien-chaitalay RoadThakamBangkok 10150Thailand Fuel Cells and Hydrogen Research and Engineering Center Pilot Plant Development and Training InstituteKing Mongkut’s University of Technology ThonburiBangkok 10140Thailand Department of Research and Development Velammal Medical College Hospital and Research InstituteMadurai 625009Tamil NaduIndia Department of Tool and Materials Engineering Faculty of EngineeringKing Mongkut’s University of Technology ThonburiBangmodBangkok 10140Thailand Research Center of Advanced Materials for Energy and Environmental Technology King Mongkut’s University of Technology ThonburiBangmodBangkok 10140Thailand School of Bioresources and Technology Nanoscience&Nanotechnology Graduate ProgrammeFaculty of ScienceKing Mongkut’s University of Technology ThonburiBangkhuntien-chaitalay RoadThakamBangkok 10150Thailand

Gel-polymer electrolytes with high thermal stability and mechanical properties were considered suitable in rechargeable batteries so as to overcome the problems encountered in liquid *** a previous study,flexible sodium-ion batteries(FSIBs)were fabri-cated using electrodes made of carbon quantum dots(CQDs)decorated with SnO_(2) and NaVO_(3) utilizing a polyvinyl alcohol(PVA)/P3HT gel-polymer electrolyte at a ratio of 1:*** addition,various separators such as indium-doped tin oxide/polyoxyethylene tridecyl ether(ITO/PTE),rice paper(RP),silicone with three big holes(SIL BH),silicone with many small holes(SIL sh)and cellulose paper(CP)were tested in flexible Na-ion *** SIL sh delivered a high specific discharge capacity of 4246 mAh g^(-1) in the initial cycle at 2 V and maintained a value of 71 mAh g^(-1) in the 50th *** the aim of improving the cyclic ability of FSIBs,different weight ratios of PVA/P3HT(1:0.025,1:0.05,1:0.1,1:0.15,1:0.2)were tried in this work using the electrodes CQDs@SnO_(2) and CQDs@NaVO_(3).The above ratios were referred to as B25,B50,B100,B150 and B200,*** sh was used as a *** voltammetry studies indicated that B150 had a high specific capacitance of 13062 F g^(-1).B25 and B100 exhibited high discharge capacities(171 mAh g^(-1))and(151 mAh g^(-1))compared to that of other ratios B50(75 mAh g^(-1)),B150(88 mAh g^(-1))and B200(54 mAh g^(-1))in the 50th cycle at 2.0 *** study reveals the scope of developing FSIBs of high capacity and cyclability at different voltages using carbonaceous electrodes and gel-polymer electrolytes with different ratios of PVA/*** focus of the present study is to bring out the optimum ratio of PVA/P3HT for maximizing the cyclic ability of FSIBs.

关键词： biomass carbon quantum dots gel-polymer electrolytes energy storage flexible Na-ion battery

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Flexible sodium-ion batteries using electrodes from Samanea saman tree leaf-derived carbon quantum dots decorated with SnO_(2) and NaVO_(3)

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Clean Energy 2021年第2期5卷 354-374页

作者： Baskar Thangaraj Surawut Chuangchote Nutthapon Wongyao Pravin raj Solomon kamonchanok Roongraung Wachira Chaiworn Werasak Surareungchai Pilot Plant Development and Training Institute King Mongkut’s University of Technology ThonburiBangkhuntien-chaitalay RoadThakamBangkok-10150Thailand Department of Tool and Materials Engineering Faculty of EngineeringKing Mongkut’s University of Technology Thonburi126 Prachauthit RoadBangmodThungkruBangkok 10140Thailand Research Center of Advanced Materials for Energy and Environmental Technology King Mongkut’s University of Technology Thonburi126 Prachauthit RoadBangmodBangkok 10140Thailand Fuel Cells and Hydrogen Research and Engineering Center Pilot Plant Development and Training InstituteKing Mongkut’s University of Technology ThonburiBangkok 10140Thailand School of Chemical and Biotechnology SASTRA-Deemed UniversityThanjavur-613402Tamil NaduIndia Integrative Biorefinery Laboratory National Center for Genetic Engineering and BiotechnologyNational Science and Technology Development AgencyPatumthani-12120Thailand School of Bioresources Technology and Nanoscience&Nanotechnology Graduate ProgrammeFaculty of ScienceKing Mongkut’s University of Technology ThonburiBangkhuntien-chaitalay RoadThakamBangkok 10150Thailand

Carbonaceous materials with large interlayer spacing and disordered structure are considered suitable as electrodes in sodium-ion batteries so as to overcome the problem encountered in conventional *** this study,carbon quantum dots(CQDs)decorated with SnO_(2)and NaVO_(3)are used as electrodes in the fabrication of flexible Na-ion *** are prepared from dead leaves of the Samanea saman tree through alkaline-peroxide treatment and hydrothermal ***-prepared CQDs exhibit a quantum yield of 21.03%at an excitation wavelength of 360 *** separators such as indium-doped tin oxide/polyoxyethylene tridecyl ether(ITO/PTE),rice paper(RP),silicone with three big holes(SIL BH),silicone with many small holes(SIL sh)and cellulose paper(CP)have been tried in flexible Na-ion *** sh achieved higher specific capacitance(881 F g-1)than other separators due to the function of many small holes on the surface of the *** SIL sh separator delivered higher discharge capacities of 141 and 114 mC g-1 at 1.5 and 2.5 V than SIL *** RP separator delivered specific discharge capacities of 1087 and 347 mC g-1 in the 1st and 50th cycles,respectively,at 1 *** RP separator delivered a high initial specific discharge capacity of 698 mC g-1 at 2 V and maintained a good discharge capacity of 222 mC g-1 in the 50th *** compared to RP,SIL sh delivered high specific discharge capacity of 4246 in 1st cycle at 2 V but maintained a capacity of 71 mC g-1 in the 50th *** study reveals the scope of developing flexible Na-ion batteries with high capacity and cyclability using carbonaceous materials derived from the leaves of the *** tree.

关键词： biomass carbon quantum dots separators gel-polymer electrolyte flexible Na-ion battery

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Composition and Regeneration of Trees in the Community Forests of Lamjung District,Nepal

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Journal of Resources and Ecology 2021年第5期12卷 658-668页

作者： Tilak Babu CHAPAGAI Dipak kHADkA Dinesh raj BHUJU Narendra raj kHANAL shI shi CUI Dafang Central Department of Environmental Science Tribhuvan UniversityKirtipur 44618Nepal Guangdong key Laboratory for Innovative Development and Utilization of Forest Plant Germplasm College of Forestry and Landscape ArchitectureSouth China Agricultural UniversityGuangzhou 510642China Golden Gate International College Tribhuvan UniversityKathmandu 4059Nepal Environment Protection and Study Center Kathmandu 44600Nepal Nepal Academy of Science and Technology Lalitpur 3323Nepal Central Department of Geography Tribhuvan UniversityKirtipur 44618Nepal

The community forest program in Nepal is one of the successful conservation *** species in a forest ecosystem have a fundamental role in maintaining the vegetation structure,complexity,and *** study analyzes the composition and regeneration of tree species in five community forests(CFs)of the sub-tropical region,Lamjung district,Nepal for preparing baseline data for long-term research projects and helps the community to manage their CFs *** species data were generated by stratified random sampling using 35 quadrate plots(size:20 m x 20 m).The density of adult trees in the forests ranged from 575 Ind ha^(-1)(Tilahar CF)to 1196 Ind/ha(Deurali Thadopakha CF).The sapling ranged from 2533 Ind ha^(-1)(Tilahar CF)to 4000 Ind ha^(-1)(Thuliban CF)and seedling from 19583 Ind ha^(-1)(Tilahar CF)to 37500 Ind ha^(-1)(Thuliban CF).Similarly,the adult tree basal area varied from 28.34 m^(2) ha^(-1)(Tilahar CF)to 49 m^(2) ha^(-1)(Deurali CF).The adult tree diversity index(shannon-Weiner’s H)also ranged from 1.08(Thuliban CF)to 1.88(Tilahar CF).The tree species such as Sapium insigne,Ficus benghalensis,Lagerstroemia parviflore,Albizia *** Pinus roxburghii were weak *** general,the forests have good regeneration status except for Tilahar Community Forest,but based on the DBH size class distribution diagram,there is no sustainable *** the five community forests the DBH size of adults was significantly different,and the DBH of Deurali Thadopakha was the *** only few species have good regeneration and most of the species have weak,poor to no *** dominancy of fewer species like shorea robusta,Castanopsis indica,and Schima wallichii accordingly maintain the overall regeneration of tree of CFs,so further plantation needs to be done inside the CF by triage accordingly those species whose regeneration has poor.

关键词： community forest composition regeneration species tree

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