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Recent Techniques in Management of Lumbosacral Region Tumours: A Prospective Comparative Study

Open Journal of Modern Neurosurgery 2018年第2期8卷 239-249页

作者： Mostafa Abd Elsamea mohamed Shaaban Ahmed taha Department of Neurosurgery Al-Azhar University Hospital Damietta Egypt

Background: The lumbosacral plexus consists of the ventral rami from the L2 to S3 nerve roots, with some additions from the L1 and S4 nerve roots as well. The standard treatment for spinal cord compression is urgent surgically decompressive laminectomy over the affected level with resection as much as possible of the exposed tumor to relieve the cord compression. We aim to correlate the impact of preoperative clinical picture, duration of symptoms, and the pathological nature of the lumbo-sacral spine tumors on the outcome of comparative study different modalities of management. Patients and Methods: During the period between 2015 and 2017, thirty cases were studied and surgically managed in Al-Azhar University Hospital, Damietta. Cases were selected for surgery if they were diagnosed as having a symptomatizing lumbosacral lesion. Results: Thirty patients were included in the current study;the commonest lesion in this study was ependymoma eight patients (27%), astrocytoma six patients (20%), and meningioma five patients (17%). Nerve sheath tumor comprised five cases (17%) with the hemangioblastomas three cases (10%), epidermoid one case (3%), and ependymoma of the filum terminale two cases (6%). The mean age of the included patients was 38.96 ± 15.42. The mean duration of lesions was 13.66 ± 10.93. They were 15 male patients (50%), and 15 female patients (50%), with male: female ratio 1:1. The mean duration of symptoms ranged for 1:60 months. The most common presenting manifestations were sensory followed by motor and sphinctric disturbance. Complications occurred in 8 patients (23%), and the most common was postoperative CSF leak. 19 out of 30 cases were surgically totally resected (63%), while 11 cases (37%) were grossly totally resected. Conclusions: Ependymoma and meningioma have more favorable outcome compared to other spinal tumors. Accurate and rapid diagnosis prior to surgery also associated with good outcome.

关键词： Lambosacral Lesion Astrocytoma Ependymoma

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The Relation between Apolipoprotein E4 Genotype and Vascular Dementia

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Advances in Aging Research 2014年第3期3卷 208-215页

作者： Tomader taha Abdel Rahman Safia mohamed Shehata Clinical Pathology Department Ain Shams University Hospitals Cairo Egypt Geriatrics Medicine Department Faculty of Medicine Ain Shams University Cairo Egypt

Most studies investigating genetics of dementia have focused on Alzheimer’s disease, but little is known about the genetics of vascular dementia (VD). The aim of this study was to identify the association between Apolipoprotein E4 (Apo E4) genotype and VD in cerebrally infarcted patients. The study was conducted on 100 patients with cerebral infarction: 50 had VD (cases) and 50 didn’t have dementia (controls). Diagnosis of VD was based on Mini-Mental State Examination, Cambridge Cognitive Examination (CAMCOG), the Diagnostic and Statistical Manual of Mental Disorders 4th edition criteria for the diagnosis of VD (DSM-IV), Hachinski Ischemic Score, and computed tomography of the brain (CT brain). Apo E4 allele was assessed through DNA genotyping. The study showed that hypertension (p = 0.027, OR = 4.71), diabetes mellitus (p = 0.003, OR = 6.05) and Apo E4 allele (p = 0.017, OR = 13.39) were the independent risk factors of VD among studied participants. The study concluded that cerebrally infarcted patients with Apo E4 genotype are at high risk of developing VD.

关键词： Apolipoprotein E4 Cerebral Infarction Genetics Vascular Dementia

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Microsurgical Management of Vestibular Schwannomas with Brainstem Compression: Surgical Challenges and Outcome

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Open Journal of Modern Neurosurgery 2020年第1期10卷 122-134页

作者： Mahmoud Saad Hosam Shata mohamed Younis Ahmed Nageeb mohamed taha Department of Neurosurgery Faculty of Medicine Mansoura University Mansoura Egypt Department of Anesthesiology Faculty of Medicine Mansoura University Mansoura Egypt

Background: Vestibular schwannomas exerting brainstem compression with or without hydrocephalus are challenging for neurosurgeons regarding the plan of surgery, operative risk and postoperative sequale. Purpose: To report our experience with the surgical challenges and outcomes for Hannover type T4a & T4b vestibular schwannomas. Methods: Retrospective case study conducted at neurosurgery department, Mansoura University between October 2016 and May 2019 of 16 patients with vestibular schwannoma compressing the brainstem. We reviewed their clinical, radiological, surgical data, incidence of complications and outcome. Results: We had 16 patients: 10 of Hanover grade T4b and 6 of grade T4a. Gross total resection was achieved in 2 cases while subtotal resection was achieved in 5 cases and in the remaining 9 cases;only partial resection was feasible. We had 4 cases of mortality. Among new onset morbidity after surgery, 3 cases had post-operative bulbar manifestation and 4 cases had brainstem dysfunction. Conclusion: Vestibular schwannomas compressing the brain stem are challenging in their clinical presentation, surgery and post-operative outcome. The outcome of patients treated with hydrocephalus prior to vestibular schwannoma surgery is better than those who did initial VS surgery. Patients presented with significant brainstem, bulbar manifestation had worse outcome and needed longer ICU stay and longer time for recovery.

关键词： Brainstem Challenges Vestibular Schwannoma

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几类典型的超分子液晶研究进展

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功能高分子学报 2009年第3期22卷 313-320页

作者：倪一萍陈建定 taha mohamed 华东理工大学材料科学与工程学院上海市先进聚合物材料重点实验室上海200237 Faculty des Sciences et Techniques UMR CNRS 5156Universite Jean-Monnet

超分子液晶结合了超分子化学和液晶两者的特点,是近年来研究的一个热点。在简述超分子化学和超分子液晶概念的基础上,对非共价键结合包括氢键型、离子型和金属络合型的超分子液晶结构和研究现状作了简介,并对超分子液晶常用的表征方法... 详细信息

超分子液晶结合了超分子化学和液晶两者的特点,是近年来研究的一个热点。在简述超分子化学和超分子液晶概念的基础上,对非共价键结合包括氢键型、离子型和金属络合型的超分子液晶结构和研究现状作了简介,并对超分子液晶常用的表征方法进行了概述。

关键词：超分子液晶非共价键

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DARM: Decremental Association Rules Mining

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Journal of Intelligent Learning Systems and Applications 2011年第3期3卷 181-189页

作者： mohamed taha Tarek F. Gharib Hamed Nassar 不详

Frequent item sets mining plays an important role in association rules mining. A variety of algorithms for finding frequent item sets in very large transaction databases have been developed. Although many techniques were proposed for maintenance of the discovered rules when new transactions are added, little work is done for maintaining the discovered rules when some transactions are deleted from the database. Updates are fundamental aspect of data management. In this paper, a decremental association rules mining algorithm is present for updating the discovered association rules when some transactions are removed from the original data set. Extensive experiments were conducted to evaluate the performance of the proposed algorithm. The results show that the proposed algorithm is efficient and outperforms other well-known algorithms.

关键词： Decremental Mining Association Rules Maintenance Updating Association Rules

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Thermomechanical Testing of GGG 40 Spheroidal Graphite Cast Iron Alloy

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Materials Sciences and Applications 2017年第3期8卷 273-280页

作者： Marwan Faisal Eman El-Shenawy mohamed A. taha Mechanical Design and Production Department Ain Shams University Cairo Egypt Department of Plastic Deformation Central Metallurgical R&D Institute Cairo Egypt

Spheroidal graphite cast iron GGG 40 was thermo-mechanically tested using thermo-mechanical simulator Gleeble-3500. Three deformation steps were successively applied on test-specimen at temperatures namely;900°C, 850°C and 750°C within the austenitic zone, at the same strain rate of 0.1 s-1. No cracks were observed, up to 50% deformation, after successive deformation steps. Stress-strain relationship obtained is correlated with previous work on SGCI with a different carbon equivalent. It was found that by decreasing the deformation temperature;for the same CE, young’s modulus, yield strength and strain hardening exponent increase. Microstructure of the deformed zone, for a specimen quenched after the final deformation step, reveals fine elongated ferrite and pearlite, as well as elongated graphite. While microstructure of the non-deformed zone subjected to the same treatment, includes coarser ferrite and pearlite with graphite spheres embedded in the matrix.

关键词： Thermo-Mechanical Behavior Spheroidal Graphite Cast Iron Gleeble-3500

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Effect of Deformation Parameters on Microstructural Evolution of GGG 40 Spheroidal Graphite Cast Iron Alloy

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Materials Sciences and Applications 2019年第6期10卷 433-450页

作者： Marwan Faisal Eman El-Shenawy mohamed A. taha Faculty of Engineering Ain-Shams University Cairo Egypt Central Metallurgical Research and Development Institute (CMRDI) Cairo Egypt

Studying the thermo-mechanical behavior of ductile iron is necessary to develop the rolling process for ductile iron sheet/strip production, thus, extending its application by replacing steel in several fields such as machine casing, constructional applications, etc. In order to predict the safe rolling conditions for producing sheets and strips, the thermo-mechanical behavior of a ductile iron alloy, with CE of 4.48, is studied by physical simulation of hot rolling process using Gleeble-3500 simulator. The test was conducted on specimens at a range of deformation temperatures from 800°C to 950°C while three different strain rates;namely 0.05, 0.1 and 0.5 s-1 were used. The results obtained, show minimum values of flow stresses at 850°C. By increasing the deformation temperature up to 900°C, the flow stresses increased to reach maximum values, beyond which the flow stress decreased again. A remarkable dynamic recrystallization is observed at the deformation temperatures of 850°C and 800°C with applied strain rates of 0.05 and 0.1 s-1. Gleeble test results are correlated with microstructure observations on samples quenched at their deformation temperatures, where the changes in structure and graphite morphology are reported. The deformation process at high temperatures namely 950°C and 900°C result in changing the graphite shape from a spheroidal-like to a saucer-like shape. However, by decreasing the deformation temperature to 850°C as well as 800°C, graphite with lamellar shape is observed. As a conclusion, ductile iron could be successfully deformed without cracking at the applied conditions.

关键词： Ductile Iron Thermo-Mechanical Behavior Gleeble-3500 Physical Simulation Graphite Morphology

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Temporal variation in chemical composition of Dictyota dichotoma (Hudson) J.V. Lamouroux (Dictyotales,Phaeophyceae) from Red Sea Coast, Egypt

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Journal of Coastal Life Medicine 2017年第4期5卷 149-155页

作者： mohamed Ali Deyab taha mohamed El-Katony Magda Faiz El-Adl Fatma mohamed Ward Department of Botany and Microbiology Faculty of ScienceDamietta UniversityNew DamiettaEgypt

Objective: To relate the chemical composition of Dictyota dichotoma (Hudson) *** (D. dichotoma) to variation of water characteristics at Hurghada, ***: Sea water and D. dichotoma fronds were collected from Hurghada shores, during autumn of 2014. Water samples were analyzed and fronds of D. dichotoma were biochemically ***: Sea water was characterized with high levels of salinity, P and heavy metals but with low content of nitrogen. The confined nature and the high evaporation of the Red sea contribute to the high salinity while the mining and transportation of phosphatic ore in the nearby region contribute to the high load of P and heavy metals. With the progress of season from September to November, water temperature was markedly reduced whereas pH and ionic content of water was reduced to a lesser extent, with marked alteration in ionic composition. With the progress of season towards winter, there was marked reduction in mineral composition of the fronds, shift in frond composition in favor of carbohydrates at the expense of proteins, lipids and alginates;and shift in the pigment composition in favor of chlorophylls at the expense of carotenoids and ***: These facts point to active growth and photosynthetic activity during the cold period;that is, D. dichotoma is a cold water alga. D. dichotoma had moderate nutritive value, with moderate contents of carbohydrates, proteins, lipids and minerals. The mineral accumulation capacity of the fronds was more evident for N, P and K than for Ca, Mg and heavy metals.

关键词： Alginates Minerals Pigments Red sea

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Vitamin D Level in Multiple Sclerosis Patients. Could Vitamin D Level Be Routine Investigation for Multiple Sclerosis Patients?

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Neuroscience & Medicine 2014年第5期5卷 201-204页

作者： mohamed Hamdy Ibrahim taha Kamel Alloush mohamed Khalid Abdul Rahim Neurology Department Faculty of Medicine Ain Shams University Cairo Egypt Internal Medicine Department Gulf Medical University Ajman United Arab of Emirates

Objectives: To study the prevalence of vitamin D deficiency among newly diagnosed multiple sclerosis patients. Patients and Methods: It is a case control cross matching age related study done on totally 40 subjects (20 patients are newly diagnosed as MS;patients don’t start any medication for MS (naive patients) and 20 subjects are controls with the same age and sex). Base line vitamin D level was measured (i.e. vitamin D, 25-OH (total)) and MRI brain with contrast was done for all patients. Results: Low total vitamin D level was seen among 65% of patients with MS (13/20);however, this was only 20% of normal controls (4/20). Conclusion: Hypovitaminosis D is common in MS patients.

关键词： Low Vitamin D Multiple Sclerosis

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Helicobacter Pylori Infection Is Associated with Dyslipidemia and Increased Levels of Oxidized LDL in Type-2 Diabetes Mellitus

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Journal of Diabetes Mellitus 2016年第3期6卷 185-190页

作者： mohamed Hasan Mukhtar Wesam Ahmed Nasif Abdullatif taha Babakr Department of Medical Biochemistry Faculty of Medicine Umm Al-Qura University Makkah KSA Molecular Biology Department Genetic Engineering and Biotechnology Research Institute Sadat City University Sadat City Egypt

Emerging data now indicate and address the strong relationship between H. pylori infection and the incidence of Type 2 DM, a growing body of evidence suggests that the infection with H. pylori may be associated with insulin resistance, chronic inflammation, long-term diabetes complications, and cardiovascular risk factors. The present study was conducted to evaluate the relationship between the infection with Helicobacter pylori and disturbance in Lipid profile in Type 2 Diabetic patients. One hundred and five participants were enrolled, categorized into two groups of H. pylori positive cases and negative controls according to their results of H. pylori IgG antibodies. Subjects in both groups fill the structured questionnaire. Blood samples were drawn for measuring the FBS, 2hr-PP blood sugar, HbA1c, Lipid profile and oxidized LDL. The obtained results were statistically analyzed. The study methodology was approved by the Biomedical Ethics Committee in the Faculty of Medicine, Umm Al-Qura University, Makkah, KSA. 48 cases (45.7%) were diagnosed as H. pylori seropositive and 57 (54.3%) were negative. There is no significant difference in the mean age or mean BMI between the H. pylori negative and positive cases. Glycemic control was similar in the two groups. Total Cholesterol was higher in cases of positive H. pylori compared to negative controls (P < 0.001) and Triglycerides was significantly elevated too (P < 0.005). No significant difference in the levels of HDL-Cholesterol between the two groups, while the mean LDL-Cholesterol was found to be significantly increased in cases of H. pylori positive compared to negative controls (P < 0.001). Oxidized LDL levels in the positive cases was found to be increased significantly (P = 0.001) compared to negative controls. Infection with H. pylori is associated with increased levels of Total Cholesterol, Triglycerides, LDL-C and oxidized LDL in Type 2 Diabetic patients.

关键词： H. pylori Diabetes Oxidized LDL

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