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Social Networks as a Didactic Support to Prevent Addictions in Nursing Students

Open Journal of Nursing 2023年第4期13卷 217-225页

作者： Diana Cecilia Tapia-Pancardo rafael Villalobos-molina Biomedicine Unit Graduate and Research Division Faculty of Higher Studies Iztacala National Autonomous University of Mexico Tlalnepantla Mexico

Health professionals and mainly nurses must be kept updated on context conditions where populations they have in charge, since this is the only way to maintain communication with those vulnerable groups avoiding barriers, there are topics of difficult approach such as the use and abuse of substances in adolescents, and currently adolescents communicate through social networks. We aimed to determine the influence of social networks as a pedagogic strategy in adolescents’ health education. Method: Qualitative and descriptive study with phenomenological design. Fifteen informants from nursing career participated, and selected by convenience. Data collection was through a semi-structured interview composed of 5 questions directed to informants, regarding their experience to make an informative video about use and abuse in adolescents;questions were about their experiences, found difficulties and any other element related with the making of the video, its spread, the login and acceptance that the audiovisual material had in social networks by students and the management of information with preventive goals. All final products were incorporated to a link where group members, as well as the student community, could revise the video and make comments, maintain a chat with others, and so on, a dynamic session of presentations on questions and comments was done. An informed consent was signed. Collected qualitative data were analyzed according to De Souza Minayo. Results: Three categories emerged with nine sub-categories, Category 1: Influence of social networks on students, sub-categories: 1.1) Perception about addictions, 1.2) Expectation on attention to addictions, 1.3) As educational strategy. Category 2: Experiences of students with social networks, sub-categories: 2.1) Motivates creativity, 2.2) Rescue learned skills and add others, 2.3) Motivates empathy. Category 3: Use of social networks by nurse students, sub-categories: 3.1) Constraint in videos production, 3.2) Ad

关键词： Social Networks Addiction Prevention Adolescents

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Tracheal relaxation of five medicinal plants used in Mexico for the treatment of several diseases

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Asian Pacific Journal of Tropical Medicine 2014年第3期7卷 179-183页

作者： Amanda Snchez-Recillas Paul Mantecón-Reyes Patricia Castillo-Espaa rafael Villalobos-molina Maximiliano Ibarra-Barajas Samuel Estrada-Soto Facultad de Farmacia Universidad Autonoma del Estado de MorelosAvenida Universidad 1001.Col.ChamilpaCuernavacaMorelos 62209México Centro de Investigación en Riotecnología Universidad Autónoma del Estado de Morelos.Avenida Universidad 1001Col.ChamilpaCuernavacaMorelos 62209México Unidad de Biomedicina Facultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantlaEstudo de Mexico 54090México

Objective:To assess the relaxant effect of several organic extracts obtained from Agastache mexicana(***),Cochlospermum vitifolium(***),Cordia morelosana(***),Lepechinia caulescens(***)and Talauma mexicana(71 mexicana)used in Mexican traditional medicine for the treatment of several ***:Extracts were obtained by maceration at room temperature using hexane,dicliloromethane and methanol for each plant *** organic extracts were evaluated ex vivo to determine their relaxant activity on the contractions induced by carbaehol(cholinergic receptor agonist,1μmol/L in isolated rat tracheal ***:A total of 15 extracts were evaluated(three for each species).All test samples showed significant relaxant effect,in a concentration-dependent manner,on the contractions induced by 1μmol/L carbachol,with exception of extracts from *** extracts were less potent than theophylline[phosphodiesterase inhibitor,EC_(50):(28.79±0.82)μg/mL]that was used as positive ***-response curves revealed that the extracts with more significant effects were dichloromethanic extracts of ***[E_(max):(103.03±3.32)%and EC_(50):(159.39±3.72)μg/mL)and ***[Emax:(106.58±2.42)%and EC_(50):(219.54±7.61)μg/mL].Finally,hexanic and dichloromethanic extracts from *** were fully effective but less potent than ***,and ***:Less polar extracts obtained from ***,71 mexicana and *** exhibited greater relaxant effect on tracheal rat rings,which allows us to suggest them as sources for the isolation of bioactive molecules with potential therapeutic value in the treatment of asthma.

关键词： Asthma Mexican medicinal plants Trachea Relaxant effect

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Perception of Losses Experienced by the Diabetic Patient

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Open Journal of Nursing 2022年第9期12卷 571-580页

作者： Diana Cecilia Tapia-Pancardo Lucia Velázquez-Hernández rafael Villalobos-molina Graduate and Research Division Biomedicine Unit Faculty of Higher Studies Iztacala National Autonomous University of Mexico Tlalnepantla Mexico National Autonomous University of Mexico Tlalnepantla Mexico

A person living with diabetes mellitus is conscious that this pathology will not cause its death in the short term, but they face losses and experience grief on multiple occasions along with the chronicity of the disease. In most cases, the partner or close relative also experiences a great impact since they become a family caregiver. The goal of this study was: to analyze the perception of losses experienced by the diabetic patient along with the chronicity of the illness. Method: This was qualitative research, with a phenomenological method under the philosophical view of Husserl and the theoretical support of Kübler-Ross with a descriptive design. Four diabetic patients aged 18 to 75 years old of both genders participated;they asked for hospital attention due to complications of the disease. Selection of participants was by convenience up to reach saturation. Data were collected through semi-structured interviews, field notes and observation. The setting of the first contact was in a third-level hospital in Mexico City;the second one was through programmed home visits. These occurred by a chronogram agreed upon by the participants, and a room was selected with conditions of privacy to conduct the interviews;respect was always observed. Participants signed informed consent. Data analysis was according to Miles and Huberman, by means of three tasks: information acquisition, data transcription and codification, and conclusions. Results: After the qualitative analysis four categories emerged, as well as sub-categories, as follows: Category 1: Self-losses perceived by the patient, sub-categories 1.1 Beginning the mourn step: Negation;1.2 Silent illness that produces severe damage;1.3 Complicated/chronic mourn. Category 2: Emotions along the disease chronicity, sub-categories 2.1 Negation of emotions/distortion of natural emotions;2.2 Decisions taken based on feelings. Category 3: Changes in the diabetic patient’s nutrition, sub-categories 3.1 Culture: positive reinfor

关键词： Diabetes Patient Physical and Emotional Losses Thanatology

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鳞状上皮细胞癌抗原水平新检测方法在宫颈癌、肺癌和头颈部癌鉴别诊断中的性能及临床表现

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中国肺癌杂志 2018年第7期21卷 J0001-J0012页

作者： Stefan HOLDENRIEDER rafael molina Ling QIU Xiuyi ZHI Sandra RUTZ Christine ENGEL Pia KASPER- SAUER Farshid DAYYANI Catharina Mkorse 波恩大学医院德国波恩巴塞罗那医院巴塞罗那大学西班牙巴塞罗那北京协和医院中国北京首都医科大学宣武医院中国北京罗氏诊断公司德国Penzberg 罗氏诊断公司德国Mannheim 罗氏诊断国际有限公司瑞士Rotkreuz 加利福尼亚大学美国Irvine CA 荷兰癌症研究院荷兰阿姆斯特丹

鳞状上皮细胞癌抗原水平在鳞状上皮细胞癌中通常升高。这项多中心研究评估了一种新的Elecsys?鳞状上皮细胞癌检测的检测性能,该检测方法是以等摩尔方式测量血清鳞状上皮细胞癌抗原1和2的水平,并研究了鳞状上皮细胞癌抗原用于宫颈癌、肺... 详细信息

鳞状上皮细胞癌抗原水平在鳞状上皮细胞癌中通常升高。这项多中心研究评估了一种新的Elecsys?鳞状上皮细胞癌检测的检测性能,该检测方法是以等摩尔方式测量血清鳞状上皮细胞癌抗原1和2的水平,并研究了鳞状上皮细胞癌抗原用于宫颈癌、肺癌和头颈部鳞状上皮细胞癌鉴别诊断的潜能。在欧洲三个研究中心进行了精确度和方法学比较实验。健康人群的参考区间使用来自欧洲和中国人群的样本确定的。鉴别诊断试验确定了鳞状上皮细胞癌抗原水平能否将宫颈癌、肺癌或头颈癌与表观健康的、良性的或其他恶性群组区分开来。根据95%特异性下的鳞状上皮细胞癌抗原水平计算出鳞状上皮细胞癌抗原医学截断值。9个分析浓度的重复性变异系数<5.3%,中间精密变异系数<0.3%。方法学比较显示,与Architect和Kryptor系统具有很好的相关性(斜率分别为1.1和1.5)。表观健康人群的第95百分位数的参考区间为2.3 ng/m L(95%置信区间:1.9-3.8;欧洲队列,n=153)和2.7 ng/m L(95%置信区间:2.2-3.3;中国队列,n=146)。最佳的鉴别诊断结果见于宫颈鳞状上皮细胞癌:受试者工作特征曲线分析显示鳞状上皮细胞癌抗原水平(2.9 ng/m L的医学截断值)鉴别宫颈鳞状上皮细胞癌(n=127)与表观健康女性(n=286;曲线下面积:86.2%;95%置信区间:81.8-90.6;灵敏度:61.4%;特异性:95.6%),良性疾病(n=187;曲线下面积:86.3%;95%置信区间:81.2-91.3;灵敏度:61.4%;特异性:95.0%)和其他宫颈癌(n=157;曲线下面积:78.9%;95%置信区间:70.8-87.1;灵敏度:61.4%;特异性:86.7%)。鳞状上皮细胞癌还可帮助鉴别诊断肺癌。Elecsys鳞状上皮细胞癌检测技术在宫颈鳞状上皮细胞癌的临床实践中表现出了良好的性能,适合用于鉴别诊断。

关键词：鳞状上皮细胞癌免疫检测颈部肺部头部颈部

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Altered Liver Gene Expression Due to Hypertension and Age in Rats

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Journal of Biosciences and Medicines 2023年第8期11卷 82-94页

作者： María Dolores Ronquillo-Sánchez Jorge Ramírez-Salcedo Itzell Alejandrina Gallardo-Ortíz rafael Villalobos-molina Unidad de Biomedicina Facultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México Tlalnepantla México Departamento de Biología Celular y del Desarrollo Instituto de Fisiología Celular Universidad Nacional Autónoma de México Ciudad de México México Carrera de Enfermería Facultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México Tlalnepantla México

Hypertension and metabolic syndrome, both of which increase with age, are multifactorial disorders. Their etiology is complex, making it challenging to isolate involved genes. This study aimed to characterize the hepatic gene expression in spontaneously hypertensive rats (SHR) at different ages. Blood pressure in SHR was determined by tail-cuff method at one and three months of age. Hepatic RNA was isolated and gene expression was compared using microarrays. Comparison between SHR and normotensive rats revealed significant variation in gene expression: 98 genes were upregulated and 122 were downregulated in SHR;while 88 genes were upregulated and 139 genes were downregulated in age-matched normotensive rats. Furthermore, within the SHR group, 110 genes were found to be upregulated and 168 genes downregulated across different ages. Analyses via the Gene Ontology, and Kyoto Encyclopedia of Genes and Genomes pathways revealed that several genes are potentially implicated in both, hypertension and metabolic syndrome. The results suggest that SHR display variations in gene expression due to aging, and when compared to normotensive rats. These variations could contribute to the development of hypertension and metabolic syndrome. Microarray studies involving older rats are necessary to further validate these findings.

关键词： Hypertension Metabolic Syndrome Gene Expression SHR Microarray

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The body mass index (BMI) as a public health tool to predict metabolic syndrome

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Open Journal of Preventive Medicine 2012年第1期2卷 59-66页

作者： Miguel Murguía-Romero rafael Jiménez-Flores rafael Villalobos-molina María Isabel Mendoza-Ramos Julia Reyes-Reali Santiago C. Sigrist-Flores Adolfo René Méndez-Cruz Carrera de Médico Cirujano FES Iztacala UNAM Tlalnepantla México

Objective: To analyze the body mass index (BMI) as an indicator of metabolic alterations, including the metabolic syndrome (MetS), at both individual level and public health level. Method: We recruited 3683 undergraduate students (17 - 24 years old) from México City identifying metabolic alterations, including the MetS, and comparing its prevalence by BMI ranges. We applied a sensitivity analysis to define BMI optimal cut-off point values. Results: We found 14.6% of MetS prevalence with a BMI average of 24.2%, and 34.5% of overweight prevalence (BMI ≥ 25). A BMI cut-off point value of 22.5 is suggested as an upper limit of a normal weight condition, only for public health purpose;while at individual level the BMI cut-off point of 25 was corroborated as the upper limit for a normal weight condition. A public health tool to estimate the MetS prevalence based on BMI percentages is proposed, and a study case is presented. Conclusion: BMI fails predicting at individual level both, healthy condition or metabolic alterations, when values are lower than 25. At population level, the BMI is a valuable public health tool to estimate MetS prevalence: based on the prevalence of MetS by BMI ranges of a sample of the population.

关键词： BMI Metabolic Syndrome Obesity Public Health Tool

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Emotions and Stressing Situations Adaptation of Nursing Students in the New Normality

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Health 2022年第7期14卷 766-774页

作者： Diana Cecilia Tapia-Pancardo Nancy Areli Martínez-Rangel Rocío Marisol Romero-Salgado José Luis Cadena-Anguiano rafael Villalobos-molina División de Investigación y Posgrado Unidad de Biomedicina Facultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México Tlalnepantla México Carrera de Enfermería Facultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México Tlalnepantla México Carrera de Odontología Facultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México Tlalnepantla México

Background: New normality is uncertain in every sense, specifically in education and for many health disciplines. Being immersed in COVID-19 pandemics brought serious consequences for mental health, and is very important to handle emotions and stress coping strategies to obtain positive outcomes. Objective: To identify the most frequent emotions, as well as the adaptation strategies to the new normality faced by the students of nursing. Methods: Qualitative and phenomenological research, with the participation of 20 students from both genders in the middle term of nursing career at Faculty of Higher Studies Iztacala, National Autonomous University of Mexico, from August to November 2021. Information was collected from a focal group for ten sessions;analysis was according to De Souza Minayo, and there was a signed informed consent letter from participants. Results: Four categories emerged with sub-categories. Category I Maximized emotions. Sub-categories: 1) Frustration, anger, disappointment;2) Personal disappointment, hopelessness, uncertainty;3) Depression. Category II Support elements close to the new normality. Sub-categories: 1) Family communication;2) Education for mental and physical health. Category III Stressing situations that exceeded the student. Sub-category: Disease in lovely ones. Category IV Stress coping strategies. Sub-categories: 1) Friends and relatives that help to get better;2) Family values. Informers pointed out to have maximized emotion, and having no self-control on its negative outcomes occurred;in addition, the situation was not favorable at home with several losses of loved ones, as well as a poor economy that threatened students to give up studies. Conclusion: Emotions facing this new normality are very important and should be attended to, their proper handling will result in a new learning of socio-emotional abilities, stress coping strategies development, better adaptation and informed decisions taken.

关键词： Emotions Stressing Situations Adaptation Nursing Students New Normality

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Problems-Based Learning during COVID-19 Pandemic: Experiences by Nursing Students

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Open Journal of Nursing 2021年第11期11卷 920-932页

作者： Isamar Carolina Castillo-Megchun Claudia Gabriela López-Rossell Maribel Araceli Padilla-Rivera rafael Villalobos-molina Diana Cecilia Tapia-Pancardo Nursing Career Faculty of Higher Studies Iztacala National Autonomous University of Mexico Tlalnepantla Mexico Graduate and Research Division Biomedicine Unit Faculty of Higher Studies Iztacala National Autonomous University of Mexico Tlalnepantla Mexico

Introduction: Problems-based learning (PBL) methodology seeks challenges in the daily life context, where students protagonise their own learning using new technologies as the ideal means to find updated and adequate information, for its processing and dissemination towards a better active and participative role. The aim was to analyze the usefulness and importance of PBL, as a strategy of significant learning in daily experiences of nursing students during the COVID-19 pandemic. Method: The study was qualitative and phenomenological, with 15 informant students of the Module “Attention to addictions in the health area” aged 20 - 25 years, enrolled in the sixth semester of nursing from a public university. Data were collected through oral testimonies, texts, and semi-structured interviews of relevant aspects to them in their everyday life facing the COVID-19 pandemic, telling their experiences. Students signed an informed consent, and the qualitative analysis followed De Souza Minayo. Results: Four categories emerged: Category 1. Students’ experiences along pandemic;1.1, Positive experiences;1.2, Negative experiences. Category 2. Students’ knowledge and abilities for self-care along pandemic. Category 3. Abilities to promote problem solving. Category 4. Impact and usefulness of PBL in students’ experiences for health education;4.1, Positive impact of PBL;4.2 Negative impact of PBL. Conclusion: PBL is very useful for significant learning. It opens knowledge, developing skills to face, support, debate, evaluate and make decisions;it does incorporate critical thinking and problem solving. PBL does encourage collaborative work.

关键词： PBL Nurse Students Experiences COVID-19 Pandemic

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The Acute and Chronic Effects of Co-Administration of Turmeric and Black Pepper Extracts in Genetic Hypertension

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Journal of Biosciences and Medicines 2023年第8期11卷 114-128页

作者： Ma. Guadalupe Calderón-Gallardo Lilia Castillo-Martínez Samuel Estrada-Soto Itzell A. Gallardo-Ortíz rafael Villalobos-molina Unidad de Biomedicina Facultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México Tlalnepantla México Programa de Maestría y Doctorado en Ciencias Médicas Odontológicas y de la Salud Doctorado en Investigación Clínica Experimental en Salud Universidad Nacional Autónoma de México Ciudad de México México Instituto Nacional de Nutrición Salvador Zubirán Ciudad de México México Facultad de Farmacia Universidad Autónoma del Estado de Morelos Cuernavaca México

High blood pressure is the main risk factor for cardiovascular diseases, it affects many people worldwide and is a public health problem. This study explored the acute and chronic actions of a mixture of turmeric (95% curcumin) plus black pepper (95% piperine) extracts, in the blood pressure pattern in spontaneously hypertensive rats (SHR) along they age. For the acute study male adult (4 - 7 months old) SHR and their control Wistar Kyoto rats (WKY) were used. A single oral dose of the mixture of turmeric/black pepper extracts (200 mg/2mg, respectively) suspension was administered. Tail-cuff was used to determine blood pressure during 180 min. For the chronic study, young (1-month-old) male SHR and their control WKY rats were fed with standard chow, or standard chow combined with cocoa, or combined with cocoa plus the mixture of turmeric/black pepper extracts;tail-cuff was used to determine blood pressure once a week, along 12 weeks. In a second chronic assay adult (5 months old) male SHR and their control WKY rats were fed with standard chow, or standard chow combined with cocoa, or combined with cocoa plus the mixture of turmeric/black pepper extracts;tail-cuff was used to determine blood pressure once a week, along 12 weeks. In all three studies, a decrease in systolic, diastolic and mean blood pressure was observed, being higher in SHR and negligible in WKY rats. The mixture of turmeric/black pepper extracts showed antihypertensive actions in SHR rats with no effect on WKY rats. The mixture delayed the onset of hypertension in young SHR rats.

关键词： Curcuma longa L. Peper nigrum L. Hypertension Polyphenol SHR

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Problem-Based Learning of Drug Use and Abuse during COVID-19 Contingency

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Open Journal of Nursing 2022年第2期12卷 170-180页

作者： Abraham Isaías López-González Oscar Diego Vega-Rodríguez Verónica Paolette Cañas-Pacheco rafael Villalobos-molina Diana Cecilia Tapia-Pancardo Nursing Career Faculty of Higher Studies Iztacala National Autonomous University of Mexico Tlalnepantla Mexico Graduate and Research Division Biomedicine Unit Faculty of Higher Studies Iztacala National Autonomous University of Mexico Tlalnepantla Mexico

Introduction: Nursing students’ experiences during the pandemic provoked social isolation, the way to learn and every context increasing their stress and anxiety leading to drug use and abuse, among others. Problem-based learning (PBL) is a pedagogic strategy to strengthen significant learning;then the objective was to establish PBL influence in nursing students’ experiences on drug use and abuse during COVID-19 contingency. Methods: Qualitative, phenomenological and descriptive paradigm, 12 female and male nursing students aged 20 - 24 years old from the 5th and 6th semesters participated. Information collection was through semi-structured interview and a deep one in four cases. A guide of questions about: How the pandemic impacted your life? How did you face it? And what did you learn during this process? Those questions were used. Qualitative data analysis was based on De Souza Minayo, and signed informed consent was obtained from participants. Results: Students’ experiences allowed four categories to emerge, with six sub-categories. Category I. Students’ experiences on drug use and abuse facing the sanitary contingency;Category II. Students’ skills development to identify a problem and design of appropriate solutions;Category III. Developing skills to favor interpersonal relationships;Category IV. Influence of PBL in nursing students’ experiences on drug use and abuse during the COVID-19 contingency. Conclusion: PBL favored analysis and thoughts in nursing students’ experiences on drug use and abuse during the COVID-19 contingency, they worked collaboratively, developed resilience to daily life situations, and implemented stress coping strategies with their significant learning, which diminished their risk behavior.

关键词： Problem-Based Learning Students’ Experiences in Drug Use and Abuse COVID-19 Contingency Resilience

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