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Frontiers of Environmental Science & Engineering 2024年第7期18卷 73-85页

作者： Sanggwon An Sangsoo Choi Hyeong rae Kim Jungho Hwang School of Mechanical Engineering Yonsei UniversitySeoul 02876Republic of Korea Gas Metrology Group Korea Research Institute of Standards and Science(KRISS)Daejeon 34113Republic of Korea

The World Health Organization has raised concerns about the possibility of airborne transmission in enclosed and poorly ventilated ***,rapid monitoring of airborne viruses is necessary in multi-use facilities with dense ***,an electrostatic air sampler(250 L/min)was developed in this work to obtain indoor viral aerosol samples for analysis via the Polymerase Chain Reaction(PCR).Aerosol tests with H1N1 and HCoV-229E were performed to evaluate the sample collection *** analysis,along with another aerosol test,was conducted to evaluate the recovery of the virus particles collected by the *** laboratory tests,our electrostatic sampler obtained viral samples that were detectable by PCR under the simulated viral pandemic scenario(3000 RNA copies per cubic meter of air)within 40 *** resulting cycle threshold(C)values were 35.07 and 37.1 for H1N1 and HCoV-229E,*** the performance evaluation in the laboratory,field tests were conducted in a university classroom from October 28 to December 2,*** A and HCoV-229E were detected in two air samples,and the corresponding C,values were 35.3 and *** PCR results are similar to those obtained from laboratory tests,considering the simulatedviralpandemic scenario.

关键词： Airborne virus Electrostatic sampler Rapid monitoring Indoor environment Field test

Catalpa bignonioides extract improves exercise performance through regulation of growth and metabolism in skeletal muscles

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Asian Pacific Journal of Tropical Biomedicine 2024年第2期14卷 47-54页

作者： Hoibin Jeong Dong-joo Lee Sung-Pil Kwon SeonJu Park Song-rae Kim Seung Hyun Kim Jae-Il Park Deug-chan Lee Kyung-Min Choi WonWoo Lee Ji-Won Park Bohyun Yun Su-Hyeon Cho Kil-Nam Kim Seoul Center Korea Basic Science InstituteSeoul 02841Republic of Korea Chuncheon Center Korea Basic Science InstituteChuncheon 24341Republic of Korea Research&Development Center Chungdam CDC JNPharm LLC.Chuncheon 24341Republic of Korea Department of Biomedical Technology Kangwon National UniversityChuncheon 24341Republic of Korea Yonsei Institute of Pharmaceutical Sciences College of PharmacyYonsei UniversityIncheon 21983Republic of Korea Gwangju Center Korea Basic Science InstituteGwangju 61751Republic of Korea Honam National Institute of Biological Resources 99Gohadoan-gilMokpo-siJeollanam-do58762Republic of Korea Department of Bio-analysis Science University of Science&TechnologyDaejeon34113Republic of Korea

Objective:To evaluate the effects of Catalpa bignonioides fruit extract on the promotion of muscle growth and muscular capacity in vitro and in ***:Cell viability was measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide *** proliferation was assessed using a 5-bromo-2’-deoxyuridine(BrdU)assay *** blot analysis was performed to determine the protein expressions of related *** effects of Catalpa bignonioides extract were investigated in mice using the treadmill exhaustion test and whole-limb grip strength *** composition analysis was performed using high-performance liquid chromatography(HPLC).Results:Catalpa bignonioides extract increased the proliferation of C2C12 mouse myoblasts by activating the Akt/mTOR signaling *** also induced metabolic changes,increasing the number of mitochondria and glucose metabolism by phosphorylating adenosine monophosphate-activated protein *** an in vivo study,the extract-treated mice showed improved motor abilities,such as muscular endurance and grip ***,HPLC analysis showed that vanillic acid may be the main component of the Catalpa bignonioides extract that enhanced muscle ***:Catalpa bignonioides improves exercise performance through regulation of growth and metabolism in skeletal muscles,suggesting its potential as an effective natural agent for improving muscular strength.

关键词： Catalpa bignonioides Skeletal muscle Cell proliferation Mitochondria Energy metabolism C2C12

西安,何谓十三朝古都?千年建城史带来的荣光

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城市地理 2024年第5期 18-27页

作者： rae 高鑫(图) Mr.Carrot(图) 左小朵(图) 虎子(图) 摄图网

甲辰龙年春节,春晚西安分会场干人齐诵《将进酒》的画面,让“顶流”城市西安的文旅热度再上一层楼。在这里,跨越时间长河的西安城墙,延续着数干年的历史文脉;大唐不夜城里衣翻飞的丽人,让人恍若走进《簪花仕女图》的画中;“最西安”的... 详细信息

甲辰龙年春节,春晚西安分会场干人齐诵《将进酒》的画面,让“顶流”城市西安的文旅热度再上一层楼。在这里,跨越时间长河的西安城墙,延续着数干年的历史文脉;大唐不夜城里衣翻飞的丽人,让人恍若走进《簪花仕女图》的画中;“最西安”的标识秦兵马,则见证了王朝霸业下的沧桑巨变……历经十三朝兴衰,在如今的西安,仍能窥见旧时长安的繁盛模样。

关键词：西安城墙《将进酒》一层楼历史文脉十三朝古都沧桑巨变

黄河打滚，天造新陆年轻的三角洲怎样生出万物？

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环球人文地理 2024年第11期 14-25页

作者： rae 王生晖几奥石耀臣长城杨维安潇遥生

在诠释黄河三角洲的来历前，我们须先共情黄河这条贯穿了中华民族历史的生命之河、宿命之河，懂得它是如何围绕山东丘陵翻滚咆哮，如何以万钧力量使旧物崩摧，又如何温柔积淀，成为飞鸟乐土、葱郁良田……曾有学者这样评论黄河三角洲：...

在诠释黄河三角洲的来历前，我们须先共情黄河这条贯穿了中华民族历史的生命之河、宿命之河，懂得它是如何围绕山东丘陵翻滚咆哮，如何以万钧力量使旧物崩摧，又如何温柔积淀，成为飞鸟乐土、葱郁良田……曾有学者这样评论黄河三角洲：“如果只用一个词来形容它，那就是‘新鲜’。”直至2024年，它也不过169岁，比之动辄以亿万、千万年计的古老地貌，只能算是呱呱坠地的新生儿，“新鲜得令人感动”。

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Commuting Toeplitz Operators on Fock-Sobolev Spaces of Negative Orders

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Acta Mathematica Sinica,English Series 2023年第10期39卷 1989-2005页

作者： Hong rae CHO Han-Wool LEE Department of Mathematics Pusan National UniversityBusan 46241Korea

In the setting of Fock-Sobolev spaces of positive orders over the complex plane,Choe and Yang showed that if the one of the symbols of two commuting Toeplitz operators with bounded symbols is non-trivially radial,then the other must also be *** this paper,we extend this result to the Fock-Sobolev space of negative order using the Fock-type space with a confluent hyper geometric function.

关键词： Fock–Sobolev spaces commutator of Toeplitz operators Mellin Transform Confluent Hypergeometric Function

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巴黎蓬皮杜中心为何要“闭关修行”五年？

环球人文地理 2024年第3期 50-59页

作者： rae 小盒饭子晋的时光碎片 nw7.eu Zhanpy Krists Luhaers Alex Vasey Oksana Avramenko 摄图网

2019年，巴黎圣母院遭遇火灾，超过三分之二的塔尖烧毁，标志性尖顶坍塌。历经4年修复，2024巴黎奥运会前夕，它终于回到大众视野，即将重新开放。但惊喜之余，巴黎另一地标蓬皮杜中心宣布，它要迎来“闭关”期。和巴黎偏爱倾诉古典情...

2019年，巴黎圣母院遭遇火灾，超过三分之二的塔尖烧毁，标志性尖顶坍塌。历经4年修复，2024巴黎奥运会前夕，它终于回到大众视野，即将重新开放。但惊喜之余，巴黎另一地标蓬皮杜中心宣布，它要迎来“闭关”期。和巴黎偏爱倾诉古典情怀的卢浮宫、大教堂、歌剧院不同，乔治·蓬皮杜国家艺术和文化中心（下文简称蓬皮杜中心）是一场年轻人的艺术狂欢，巴黎城中的异类。它极尽叛逆张狂之事，

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Prediction of characteristic blast-induced vibration frequency during underground excavation by using wavelet transform

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Frontiers of Structural and Civil Engineering 2022年第8期16卷 1029-1039页

作者： Tae Un PAK Guk rae JO Un Chol HAN Faculty of Mining Engineering Kim Chaek University of TechnologyPyongyang 999093Democratic People’s Republic of Korea School of Science and Engineering Kim Chaek University of TechnologyPyongyang 999093Democratic People’s Republic of Korea

Blast-induced vibration produces a very complex signal,and it is very important to work out environmental problems induced by *** this study,blasting vibration signals were measured during underground excavation in carbonaceous shale by using vibration pickup CB-30 and FFT analyzer ***,wavelet analysis on the measured results was carried out to identify frequency bands reflecting changes of blasting vibration parameters such as vibration velocity and energy in different frequency *** characteristics are then discussed in view of blast source distance and charge weight per *** analysis of results,it can be found that peak velocity and energy of blasting vibration in frequency band of 62.5–125 Hz were larger than ones in other bands,indicating the similarity to characteristics in the distribution band(31–130 Hz)of main vibration *** frequency bands were affected by blasting source distance,and the frequency band of 0–62.5 Hz reflected the change of charge weight per *** presenting a simplified method to predict main vibration frequency,this research may provide significant reference for future blasting engineering.

关键词： wavelet analysis blast-induced vibration frequency characteristics underground excavation

Pyrimidine nucleotide starvation induces a decrease in the number of effector T cells but not memory T cells

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Cellular & Molecular Immunology 2023年第8期20卷 859-860页

作者： Gwanghun Kim Hyun Mu Shin Hang-rae Kim Department of Biomedical Sciences Seoul National University College of MedicineSeoul03080Republic of Korea Department of Anatomy&Cell Biology Seoul National University College of MedicineSeoul03080Republic of Korea BK21 FOUR Biomedical Science Project Department of Anatomy&Cell BiologySeoul National University College of MedicineSeoul03080Republic of Korea Medical Research Institute Seoul National University College of MedicineSeoul03080Republic of Korea Wide River Institute of Immunology Seoul National UniversityHongcheon25159Republic of Korea

Scherer et *** the influence of de novo pyrimidine nucleotide synthesis on T-cell responses after antigen stimulation,particularly on effector and memory T-cell development[1].Their work focused on the effect of leflunomide(trade name Avara®),which is a direct inhibitor of dihydroorotate dehydrogenase(DHODH;a key enzyme in the de novo pyrimidine nucleotide pathway and located on the inner mitochondrial membrane).In this pathway,DHODH converts dihydroorotate to orotate and has been implicated in the reduction of ubiquinol to ubiquinone mediated by Complex III in the electron transport *** metabolic effects of DHODH inhibition are unclear[2,3].However,it is known to block S-phase progression by activating *** was originally approved for the treatment of rheumatoid arthritis(RA)in 1998;the mechanism involves the induction of S-phase cell cycle arrest and apoptosis,inhibiting cell proliferation and *** studies have demonstrated the therapeutic potential of leflunomide for cancer[4].Despite the efficacy of leflunomide,the mechanism by which it targets immune cells in the treatment of RA was unknown;however,the work of Scherer and colleagues has shed new light on this mechanism.

关键词： mechanism rotate convert

Evaluation of immobilizing agents as soil quality conditioners in addition to their metal(loid) immobilizing effect

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Pedosphere 2022年第2期32卷 307-316页

作者： Chaw Su LWIN Mina LEE Young-Nam KIM Gary OWENS Kwon-rae KIM Department of Soil and Water Science Yezin Agricultural UniversityYezinNaypyitaw 15013Myanmar Department of Smart-Agro Industry Gyeongsang National UniversityJinju 52725Korea Institute of Agriculture and Life Science(IALS) Gyeongsang National UniversityJinju 52828Korea Environmental Contaminants Group Future Industries InstituteUniversity of South AustralianMawson Lakes SA 5095Australia

In trace metal (TM)-contaminated agricultural soils,management of TM availability is important for safe crop *** addition,maintenance or improvement of soil quality is vital for sustainable crop *** TM phytoavailability and increased soil quality can be achieved by the application of various immobilizing agents to soil,which can supply both macronutrients and organic *** study investigated the long-term influences of four common immobilizing agents on soil biogeochemical properties and the phytoavailability of TMs in mixed metal-contaminated soil from a cultivated upland near an abandoned mining *** (L),gypsum (G),fly ash (F),and animal manure-based compost (C) were applied to pots containing contaminated soil,either individually or in *** incubation for three years under sequential cultivation of two crops and fallow,soil biogeochemical properties were determined,and Brassica rapa plant bioassay was *** phytoavailability of all TMs (both cationic metals and anionic metalloids) remained significantly lower in soils treated with immobilizing agents even after three years,when compared with the no-agent control (CK) *** addition,the soil quality was significantly improved by treatment with immobilizing *** instance,the C and L+C treatments were the most effective in improving soil physical (bulk density,porosity,and water-resistant aggregate stability),chemical (pH,organic matter,total nitrogen,cation exchange capacity,and plant-available phosphorus,magnesium,and potassium),and biological (microbial biomass carbon and dehydrogenase activity) *** improvement of soil properties and lowering of TM bioavailability were also consistent with the most significant increase in *** biomass production observed in the C treatment,followed by the L+C,G+F,L,G,F,and L+G treatments,as compared with that in *** results indicate that the function of the TM-immobilizing agent as a soil qualit

关键词： crop production metal bioavailability metal immobilization metal phytoavailability soil amendments soil biogeochemical properties soil remediation trace metals

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Why are children less affected than adults by severe acute respiratory syndrome coronavirus 2 infection?

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Cellular & Molecular Immunology 2022年第5期19卷 555-557页

作者： Chang Kyung Kang Hyun Mu Shin Wan Beom Park Hang-rae Kim Department of Internal Medicine Seoul National University College of MedicineSeoul03080Republic of Korea Department of Biomedical Sciences Seoul National University College of MedicineSeoul03080Republic of Korea BK21 FOUR Biomedical Science Project Seoul National University College of MedicineSeoul03080Republic of Korea Medical Research Institute Seoul National University College of MedicineSeoul03080Republic of Korea WideRiver Institute of Immunology Seoul National UniversityHongcheon25159Republic of Korea Department of Anatomy&Cell Biology Seoul National University College of MedicineSeoul03080Republic of Korea

An adequate immune response to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is crucial to not only clear the virus but also prevent tissue *** children generally experience a milder course of coronavirus... 详细信息

关键词： respiratory acute infection