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Effectiveness of sensory integration therapy in children,focusing on Korean children:A systematic review and meta-analysis

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World Journal of Clinical Cases 2024年第7期12卷 1260-1271页

作者： Seri Oh Jong-Sik Jang A-ra Jeon Geonwoo Kim Mihwa Kwon Bahoe Cho Narae Lee Department of Occupational Therapy Kangwon National University Graduate SchoolSamcheok 25949South Korea Department of Occupational Therapy Kangwon National UniversitySamcheok 25949South Korea Department of Occupational Therapy Ju-Ju Children Development CenterNonsansi 32985Chungcheongnam-doSouth Korea Department of Occupation Therapy Suwon Women’s UniversityGyeonggi-do 16632South Korea Hijam Center for Development of Children Ochang 28117South Korea Department of Occupational Therapy U1 UniversityChung-cheong bukdo 25949South Korea

BACKGROuND Sensory integration intervention is highly related to the child's effective interaction with the environment and the child's ***,various sensory integration interventions are being applied,but research methodological problems are arising due to unsystematic *** study aims to present the optimal intervention protocol by presenting scientific standards for sensory integration intervention through *** To prove the effectiveness of sensory integration therapy,examine the latest trend of sensory integration studies in Korea,and provide clinical evidence for sensory integration *** The database of Korean search engines,including RISS,KISS,and DBpia,was used to search for related litera.ure published from 2001 to October *** keywords,“Children”,“Sensory integration”,“Integrated sensory”,“Sensorymotor”,and“Sensory stimulation”were used in this ***,a meta-analysis was conducted on 24 selected studiesRISS,KISS,and DBpia,was used to search for related litera.ure published from 2001 to October *** keywords,“Children”,“Sensory integration”,“Integrated sensory”,“Sensorymotor”,and“Sensory stimulation”were used in this ***,a meta-analysis was conducted on 24 selected *** Sensory integration intervention has been proven effective in children with cerebral palsy,autism spectrum disorder,attention deficit/hyperactivity disorder,developmental disorder,and intellectual disability in relation to the diagnosis of *** sensory integration therapies,1:1 individual treatment with a therapist or a therapy session lasting for 40 min was most *** terms of dependent variables,sensory integration therapy effectively promoted social skills,adaptive behavior,sensory processing,and gross motor and fine motor *** The results of this study may be used as therapeutic evidence for sensory integration intervention in the clinical field of occupational therapy for

关键词： Children Meta-analysis Occupational therapy Sensory integration Sensory processing Social skills

Impact of payment source, referral site, and place of residence on outcomes after allogeneic transplantation in Mexico

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World Journal of Transplantation 2024年第2期14卷 76-87页

作者： Andrés Gómez-De León Yesica A López-Mora Valeria García-Zárate Ana Varela-Constantino Sergio u Villegas-De Leon Xitlaly J González-Leal raúl del Toro-Mijares Anna C Rodríguez-Zúñiga Juan F Barrios-Ruiz Victor Mingura-Ledezma Perla R Colunga-Pedraza Olga G Cantú-Rodríguez César H Gutiérrez-Aguirre Luz Tarín-Arzaga Elías E González-López David Gómez-Almaguer Hematology Service Universidad Autónoma de Nuevo LeónFacultad de Medicina y Hospital Universitario Dr.JoséEleuterio GonzálezMonterrey 64460Nuevo LeónMexico Hemato-logy Service Clínica Gómez AlmaguerMonterrey 64710Nuevo LeónMexico Hematology Service Instituto Tecnológico de Estudios Superiores de MonterreyTec SaludEscuela de Medicina Ignacio SantosMonterrey 64710Nuevo LeónMexico

BACKGROuND The impact of social determinants of health in allogeneic transplant recipients in low-and middle-income countries is poorly *** observational study analyzes the impact of place of residence,referring institution,and transplant cost coverage(out-of-pocket vs government-funded vs private insurance)on outcomes after allogeneic hematopoietic stem cell transplantation(alloHSCT)in two of Mexico's largest public and private *** To evaluate the impact of social determinants of health and their relationship with outcomes among allogeneic transplant recipients in *** In this retrospective cohort study,we included adolescents and adults≥16 years who received a matched sibling or haploidentical transplant from *** were selected without regard to their diagnosis and were sourced from both a private clinic and a public university Hospital in *** payment groups were compared:Out-of-pocket(OOP),private insurance,and a federal universal healthcare program“Seguro Popular”.Outcomes were compared between referred and institution-diagnosed patients,and between residents of Nuevo Leon and *** outcomes included overall survival(OS),categorized by residence,referral,and payment *** outcomes encompassed early mortality,event-free-survival,graft-versus-host-relapse-free survival,and non-relapse-mortality(NRM).Statistical analyses employed appropriate tests,Kaplan-Meier method,and Cox proportional hazard regression *** software included SPSS and R with tidycmprsk *** Our primary outcome was overall *** included 287 patients,n=164 who lived out of state(57.1%),and n=129 referred from another institution(44.9%).The most frequent payment source was OOP(n=139,48.4%),followed by private insurance(n=75,26.1%)and universal coverage(n=73,25.4%).No differences in OS,event-free-survival,NRM,or graft-versus-host-relapse-free survival were observed for patients dia

关键词： Hematopoietic cell transplant Social determinants of health Geography Haploidentical Out-of-pocket Financial toxicity Survival Health services and outcomes Hematopoietic malignancy Aplastic anemia

Hölder,Sobolev,weak-type and BMO estimates in mixed-norm with weights for parabolic equations

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Science China Mathematics 2021年第1期64卷 129-154页

作者： Pablo raúl Stinga José L.Torrea Department of Mathematics Iowa State UniversityAmesIA50011USA Departamento de Matemáticas Universidad Autónoma de MadridMadrid28049Spain

We prove weighted mixed-norm Lqt(W2,px)and Lqt(C2,αx)estimates for 10,x∈Rn.x∈Rn,The coefficients a(t)=(aij(t))are just bounded,measurable,symmetric and uniformly ***,we show strong,weak type and BMO-Sobolev estimat... 详细信息

We prove weighted mixed-norm Lqt(W2,px)and Lqt(C2,αx)estimates for 1ulas for derivatives,for the solutions u=u(t,x)to parabolic equations of the form∂tu−aij(t)∂iju+u=f,t∈,x∈n and for the Cauchy problem{∂tv−aij(t)∂ijv+v=fv(0,x)forfort>0,x∈Rn.x∈Rn,The coefficients a(t)=(aij(t))are just bounded,measurable,symmetric and uniformly ***,we show strong,weak type and BMO-Sobolev estimates with parabolic Muckenhoupt *** is quite remarkable that most of our results are new even for the classical heat equation∂tu−Δu+u=f.

关键词： Calderón-Zygmund parabolic singular integrals weak type and BMO estimates representation formulas parabolic equations mixed-norm Sobolev and Schauder estimates

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厂拌沥青混合料的疲劳特性

石油沥青 1992年第1期6卷 28-31页

作者： u tha XYAN ZAN 郭忠印英国诺丁汉大学土木系同济大学道交系

本文利用间接拉伸试验方法对厂拌沥青混合料的疲劳特性进行了试验分析,并将试验结果与设计方法用疲劳方程进行了对比分析;以便了解间接拉伸疲劳试验方法的可行性和厂拌沥青混合料的疲劳特性及其质量变异。

关键词：厂拌沥青混合料间接拉伸疲劳特性动态劲度

Extrahepatic hepcidin production:The intriguing outcomes of recent years

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World Journal of Clinical Cases 2019年第15期7卷 1926-1936页

作者： raêd Daher Thibaud Lefebvre HervéPuy Zoubida Karim universitéParis Diderot Bichat siteParis 75018France Inflammation Research Center(CRI) INSERM U1149/ERL CNRS 8252Paris 75018France Laboratory of Excellence GR-ExParis 75018France

Hepcidin is the hyposideremic hormone regulating iron *** is a defensin-like disulfide-bonded peptide with antimicrobial *** main site of hepcidin production is the liver where its synthesis is modulated by iron,inflammation and erythropoietic ***,hepcidin locally produced in several peripheral organs seems to be an important actor for the maintenance of iron homeostasis in these *** review highlights the presence of peripheral hepcidin and its potential *** the role of extrahepatic hepcidin could be of great physiological and therapeutic importance for several specific pathologies.

关键词： Hepcidin Extrahepatic hepcidin Iron metabolism Bacterial infection Inflammation

Influence of Nitrogen Levels and Application Methods on Yield and Quality of Sorghum

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Pedosphere 2008年第2期18卷 236-241页

作者： A.raSHID R.u.KHAN H.uLLAH Arid Zone Research Irstitute Department of Agronomy Faculty of Agriculture Gomal University

A field study was conducted for two years at the Arid Zone Research Institute, Dera Ismail Khan, Pakistan, to determine the optimum level of nitrogen and efficient application method in the production of sorghum （Sorghum bicolor L.）. using four levels of nitrogen, i.e., 0, 60, 90, and 120 kg ha^-1, and two different application methods （soil application and foliar spray）, the experiment was laid out in a split-plot design, where the main plots were used to determine the effective method of application and the subplots were used to detect the influence of N levels on the grain yield. The average data obtained after two years of study indicated an increase in the grain yields with an increase in N levels irrespective of the method used of N application. The grain yield increased from 2.92 to 5.61 t ha^-1 in the plots that were treated with 90 kg N ha^-1 compared with the control plots. Quadratic regression analysis showed that the increase in the yield was higher at the lower levels of N compared with the succeeding higher levels. The soil application method, producing an average grain yield of 4.79 t ha^-1, was found to be superior to the foliar spray method with an average grain yield of 4.56 t ha^-1. The protein content of the grain showed a linear increase with N application, attaining the maximum at 120 kg N ha^-1 in both the methods of N application. In addition, compared with the method of soil application, higher crude protein contents were observed using the method of foliar spray at all N levels.

关键词： foliar spray grain yield N level protein content soil application

Glutamine metabolism in cancer therapy

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Cancer Drug Resistance 2018年第3期1卷 126-138页

作者： Tra-Ly Nguyen raúl V.Durán Institut Européen de Chimie et Biologie INSERM U1218Universitéde Bordeaux2 Rue Robert Escarpit33607 PessacFrance.

The amino acid glutamine plays a key role in the metabolism of highly proliferating *** malignant transformation,cancer cells modify the consumption and processing of glutamine to sustain cell growth and *** some cases,these cancer cells become addicted to ***,targeting the metabolism of glutamine has been developed during last years as a potential strategy against *** this review,we summarized the last advances in our knowledge about the role of glutamine metabolism in cancer therapy.

关键词： Cancer glutamine glutamoptosis metabolism mammalian target of rapamycin

Climate Change Impacts on Environmental Hazards on the Great Hungarian Plain, Carpathian Basin

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International Journal of Disaster Risk Science 2014年第2期5卷 136-146页

作者： Gábor Mezosi Teodóra Bata Burghard C.Meyer Viktória Blanka Zsuzsanna Ladányi Department of Physical Geography and Geoinformatics University of SzegedEgyetem u.2-6Szeged 6722Hungary

The potential impacts of climate change on the Great Hungarian Plain based on two regional climate models,REMO and ALADIN,were analyzed using indicators for environmental *** the climate parameters(tempera.ure,precipitation,and wind)will change in the two investigated periods(2021–2050 and 2071–2100),their influences on drought,wind erosion,and inland excess water hazards are modeled by simple predictive *** hazards on arable lands will increasingly affect the productivity of agriculture compared to the reference period(1961–1990).The models predict an increase between 12.3%(REMO)and 20%(ALADIN)in the first period,and between 35.6%(REMO)and 45.2%(ALADIN)in the second *** increase of wind erosion hazards is not as obvious(+15%for the first period in the REMO model).Inland excess water hazards are expected to be slightly reduced(-4 to 0%)by both model predictions in the two periods without showing a clear tendency on *** three indicators together give a first regional picture of potential hazards of climate *** predictive model and data combinations of the regional climate change models and the hazard assessment models provide insights into regional and subregional impacts of climate change and will be useful in planning and land management activities.

关键词： Great inland drought

Synergy and translation of allogenic bone marrow stem cells after photodynamic treatment of rheumatoid arthritis with tetra sulfonatophenyl porphyrin and TiO2 nanowhiskers

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Nano Research 2016年第11期9卷 3305-3321页

作者： Fawad u. Rehman Chunqiu Zhao Changyu Wu Xiaoqi Li Hui Jiang Matthias Selke Xuemei Wang State Key Laboratory of Bioelectronics School of Biological Science and Medical Engineering Southeast University Nanjing 210096 China Department of Chemistry and Biochemistry California State University Los Angeles CA 90032 USA Nanjing Foreign Language School Nanjing 210096 China

Rheumatoid arthritis （ra） etiology and amelioration remains a challenge in modern therapeutics. Herein, we explored the synergistic effect of allogenic bone marrow stem cell （BMSC） translation and photodynamic treatment of ra with tetra sulfonatophenyl porphyrin （TSPP） and TiO2 nanocomposites as a new strategy for ra theranostics. The translation of BMSCs with miRNAs into infected joints in long bones post-photodynamic therapy is helpful for treating and understanding ra pathophysiology. We observed that allogenic BMSC translation combined with TSPP-TiO2 nanocomposites can significantly （p 〈 0.01） lower the concentrations of serum biomarkers （tumor necrosis factor-α and interleukin-17） in a collagen induced arthritis （CIA） murine model, both in vitro and in vivo, as well as improve other parameters such as arthritis score, BMSC count, complete blood count, and numbers of platelets, red blood cells, and white blood cells. Moreover, a fluorescent TSPP in the feet or long bones and X-ray bioimaging of ra joints revealed the clinical efficacy of BMSCs combined with TSPP-TiO2 nanocomposites. Microarray data analysis illustrated that rnomir-375-3p and rno-mir-196b-3p were up-regulated by approximately 100-fold in the BMSCs of ameliorated ra post-photodynamic therapy with TSPP-TiO2 nanocomposites. Our study not only suggests a new approach for ra theranostics, but also helps in understanding ra pathophysiology.

关键词： rheumatoid arthritis allogenic bone marrowstem cells (BMSCs) tetra sulfonatophenyl porphyrin (TSPP)-TiO2nanocomposites photodynamic treatment miRNAs