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On characterizations of isometries on function spaces

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Science china mathematics 2008年第4期51卷 620-631页

作者： LI SongYing~(1+) ruan yingbin~2 1 department of mathematics university of California Irvine CA 92697 USA 2 School of mathematics and Computer Science fujian normal university fuzhou 350007 china department of mathematics University of California Irvine USA School of mathematics and Computer Science Fujian Normal University Fuzhou China

The paper gives characterization for an isometric isomorphism on little Bloch space, VMOA and holomorphic Besov space over the unit ball B n in ? n .

关键词： ismometry Besov spaces 32A17 47A15

Surface modification of LiNi_(1/3)Co_(1/3)Mn_(1/3)O_2 with Cr_2O_3 for lithium ion batteries

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Rare Metals 2012年第2期31卷 140-144页

作者： Li, Xiaowei Lin, yingbin Liin, Ying Lai, Heng Huang, Zhigao Physics department Fujian Normal University Fuzhou 350007 China

Cr 2 O 3-coated LiNi 1/3 Co 1/3 Mn 1/3 O 2 cathode materials were synthesized by a novel method. The structure and electrochemical properties of prepared cathode materials were measured using X-ray diffraction (XRD), scanning electron microscopy (SEM), charge-discharge tests, cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). The measured results indicate that surface coating with 1.0 wt% Cr 2 O 3 does not affect the LiNi 1/3 Co 1/3 Mn 1/3 O 2 crystal structure (α-NaFeO 2 ) of the cathode material compared to the pristine material, the surfaces of LiNi 1/3 Co 1/3 Mn 1/3 O 2 samples are covered with Cr 2 O 3 well, and the LiNi 1/3 Co 1/3 Mn 1/3 O 2 material coated with Cr 2 O 3 has better electrochemical performance under a high cutoff voltage of 4.5 V. Moreover, at room temperature, the initial discharging capacity of LiNi 1/3 Co 1/3 Mn 1/3 O 2 material coated with 1.0 wt.% Cr 2 O 3 at 0.5C reaches 169 mAh·g 1 and the capacity retention is 83.1% after 30 cycles, while that of the bare LiNi 1/3 Co 1/3 Mn 1/3 O 2 is only 160.8 mAh·g 1 and 72.5%. Finally, the coated samples are found to display the improved electrochemical performance, which is mainly attributed to the suppression of the charge-transfer resistance at the interface between the cathode and the electrolyte.

关键词： lithium ion batteries LiNi 1/3 Co 1/3 Mn 1/3 O 2 Cr 2 O 3 coating

中性粒细胞胞外诱捕网浸润促进尿道创伤后尿道成纤维细胞活化和增生性瘢痕形成

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中国病理生理杂志 2024年第1期40卷 103-109页

作者：陈烨辉许以城阮中天林婷婷薛学义许宁福建医科大学附属第一医院泌尿外科福建福州350005

目的:探讨中性粒细胞胞外诱捕网(NETs)对创伤后尿道瘢痕形成的影响。方法:(1)2021年6月至2022年12月,收集福建医科大学附属第一医院泌尿外科患者的临床样本,比较尿道创伤患者(n=20)与健康志愿者(n=20)血液和尿液NETs水平的差异,并分析... 详细信息

目的:探讨中性粒细胞胞外诱捕网(NETs)对创伤后尿道瘢痕形成的影响。方法:(1)2021年6月至2022年12月,收集福建医科大学附属第一医院泌尿外科患者的临床样本,比较尿道创伤患者(n=20)与健康志愿者(n=20)血液和尿液NETs水平的差异,并分析其与尿道瘢痕形成的关系。(2)从尿道瘢痕组织中提取原代尿道成纤维细胞,体外诱导中性粒细胞以获得NETs,分别以生理盐水、0.5 mg/L NETs和1.5 mg/L NETs处理尿道成纤维细胞,探索NETs对尿道成纤维细胞活化和胶原合成的影响。(3)构建尿道创伤新西兰兔模型,将动物分为非手术组、手术+转化生长因子β1(TGF-β1)注射(阳性对照)组、手术+生理盐水注射组和手术+脱氧核糖核酸酶I(DNase I)溶液注射组,探索NETs降解剂DNase I对尿道瘢痕形成的治疗作用。结果:尿道创伤后,患者尿液NETs水平显著升高(P0.05)。尿道创伤新西兰兔模型中,创伤后尿液NETs水平越高,形成的尿道瘢痕纤维化程度越高(P<0.05);在细胞层面上,NETs促进尿道成纤维细胞活力、迁移与胶原合成(P<0.05)。在新西兰兔尿道创伤模型中,创伤后尿道注射DNase I可降低局部NETs水平,抑制尿道瘢痕形成(P<0.05)。结论:NETs浸润促进尿道创伤后尿道成纤维细胞活化和增生性瘢痕形成。

关键词：中性粒细胞胞外诱捕网创伤后尿道狭窄瘢痕形成尿道成纤维细胞

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Electrochemical properties of carbon-coated LiFePO_4 and LiFe_(0.98)Mn_(0.02)PO_4 cathode materials synthesized by solid-state reaction

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Rare Metals 2012年第2期31卷 145-149页

作者： Lin, Ying Zeng, Baozhi Lin, yingbin Li, Xiaowei Zhao, Guiying Zhou, Ting Lai, Heng Huang, Zhigao department of Physics Fujian Normal University Fuzhou 350007 China

Olivine structured LiFePO 4 /C (lithium iron phosphate) and Mn 2+ -doped LiFe 0.98 Mn 0.02 PO 4 /C powders were synthesized by the solid-state reaction. The effects of manganese partial substitution and different carbon content coating on the surface of LiFePO 4 were considered. The structures and electrochemical properties of the samples were measured by X-ray diffraction (XRD), cyclic voltammetry (CV), charge/discharge tests at different current densities, and electrochemical impedance spectroscopy (EIS). The electrochemical properties of LiFePO 4 cathodes with x wt.% carbon coating (x= 3, 7, 11, 15) at =0.2C, 2C (1C= 170 mAh·g 1 ) between 2.5 and 4.3 V were investigated. The measured results mean that the LiFePO 4 with 7 wt.% carbon coating shows the best rate performance. The discharge capacity of LiFe 0.98 Mn 0.02 PO 4 /C composite is found to be 165 mAh·g 1 at a discharge rate, = 0.2C, and 105 mAh·g 1 at =2C, respectively. After 10 cycles, the discharge capacity has rarely fallen, while that of the pristine LiFePO 4 /C cathode is 150 mAh·g 1 and 98 mAh·g 1 at =0.2 and 2C, respectively. Compared to the discharge capacities of both electrodes above, the evident improvement of the electrochemical performance is observed, which is ascribed to the enhancement of the electronic conductivity and diffusion kinetics by carbon coating and Mn 2+-substitution.

关键词： lithium ion batteries LiFePO 4 carbon coating Mn-doping

Scalable synthesized high-performance TiO_(2)-Si-C hybrid anode for lithium batteries

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Journal of Energy Chemistry 2023年第2期77卷 348-358,I0009页

作者： Liao Shen Chengjie Xu Jingguo Gao Jianming Tao Qiaobao Zhang Yue Chen yingbin Lin Zhigao Huang Jiaxin Li College of Physics and Energy Fujian Provincial Solar Energy Conversion and Energy Storage Engineering Technology Research CenterFujian Normal UniversityFuzhou 350117FujianChina fujian Provincial Key Laboratory of Quantum Manipulation and New Energy Materials Fuzhou 350117FujianChina fujian Provincial Collaborative Innovation Center for Advanced High-Field Superconducting Materials and Engineering Fuzhou 350117FujianChina department of Materials Science and Engineering College of MaterialsXiamen UniversityXiamen 361005FujianChina

At present,developing a simple strategy to effectively solve the shackles of volume expansion,poor conductivity and interface compatibility faced by Si-C anode in lithium batteries(LIBs)is the key to its ***,low-cost nano-Si powders were prepared from Si-waste of solar-cells by sanding treatment,which can effectively reduce the commercialization cost for Si-C ***,micro-nano structured Gr@Si/C/TiO_(2) anode materials with graphite(Gr)as the inner core,TiO_(2)-doped and carbon-coated Si as the outer coating-layer,were synthesized at kilogram-scale per milling *** characterization results indicate that TiO_(2)-doped carbon layer can improve the interface compatibility with the electrolyte,further promote the reduction of electrode polarization,and finally enhance the battery performance for the Gr@Si/C/TiO_(2) ***,Gr@Si/C/TiO_(2) composites can output excellent LIB performance,especially with high initial coulombic efficiency(ICE)of 82.51%and large average reversible capacity of~810 mA h g^(-1) at 0.8 A g^(-1) after 1000 ***,Gr@Si/C/TiO_(2)‖NCM811 pouch full cells deliver impressive performance especially with high energy density of~489.3 W h kg^(-1) based on the total weight of active materials,suggesting its promising application in the high performance LIBs.

关键词： Lithium-ion batteries Si-C anodes Kilogram-scale preparation Interface compatibility Electrochemical mechanism

Easily Obtaining Excellent Performance High-voltage LiCoO_(2)via Pr_(6)O_(11)Modification

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Energy & Environmental Materials 2023年第2期6卷 34-44页

作者： Yongcong Huang Chenjie Xu Jingguo Gao Liao Shen Qian Liu Guiying Zhao Qingshui Xie yingbin Lin Jiaxin Li Zhigao Huang College of Physics and Energy Fujian Provincial Solar Energy Conversion and Energy Storage Engineering Technology Research CenterFujian Normal UniversityFuzhou 350117China fujian Provincial Key Laboratory of Quantum Manipulation and New Energy Materials Fuzhou 350117China fujian Provincial Collaborative Innovation Center for Advanced High-Field Superconducting Materials and Engineering Fuzhou 350117China State Key Laboratory for Physical Chemistry of Solid Surfaces Fujian Key Laboratory of Materials GenomeCollaborative Innovation Center of Chemistry for Energy MaterialsCollege of MaterialsXiamen UniversityXiamen 361005China

Developing an effective method to synthesize high-performance high-voltage LiCoO_(2) is essential for its industrialization in lithium batteries(LIBs).This work proposes a simple mass-produced strategy for the first time,that is,negative temperature coefficient thermosensitive Pr_(6)O_(11) nanoparticles are uniformly modified on LiCoO_(2) to prepare LiCoO_(2)@Pr_(6)O_(11)(LCO@PrO)via a liquid-phase mixing combined with annealing *** at 274 mA g−1,the modified LCO@PrO electrodes deliver excellent 4.5 V high-voltage cycling performance with capacity retention ratios of 90.8%and 80.5%at 25 and 60℃,being much larger than those of 22.8%and 63.2%for bare LCO *** effective strategies were used to clearly unveil the performance enhancement mechanism induced by Pr_(6)O_(11) *** is discovered that Pr_(6)O_(11) can improve interface compatibility,exhibit improved conductivity at elevated temperature,thus enhance the Li^(+)diffusion kinetics,and suppress the phase transformation of LCO and its resulting mechanical *** 450 mAh LCO@PrO‖graphite pouch cells show excellent LIB performance and improved thermal safety ***,the energy density of such pouch cell was increased even by~42%at 5 *** extremely convenient technology is feasible for producing high-energy density LIBs with negligible cost increase,undoubtedly providing important academic inspiration for industrialization.

关键词： high-voltage LiCoO_(2) pouch cell Pr_(6)O_(11)modification simple massproduction thermal safety

FGF8-mediated signaling regulates tooth developmental pace during odontogenesis

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Journal of Genetics and Genomics 2022年第1期49卷 40-53页

作者： Chensheng Lin Ningsheng ruan Linjun Li Yibin Chen Xiaoxiao Hu YiPing Chen Xuefeng Hu Yanding Zhang fujian Key Laboratory of Developmental and Neural Biology and Southern Center for Biomedical Research College of Life SciencesFujian Normal UniversityFuzhouFujian 350117China department of Cell and Molecular Biology Tulane UniversityNew OrleansLA 70118USA

The developing human and mouse teeth constitute an ideal model system to study the regulatory mechanism underlying organ growth control since their teeth share highly conserved and well-characterized developmental processes, and their developmental tempo varies notably. In the current study, we manipulated heterogenous recombination between human and mouse dental tissues and demonstrated that the dental mesenchyme dominates the tooth developmental tempo and FGF8 could be a critical player during this developmental process. Forced activation of FGF8 signaling in the dental mesenchyme of mice promoted cell proliferation, prevented cell apoptosis via p38 and perhaps PI3 K-Akt intracellular signaling,and impelled the transition of the cell cycle from G1-to S-phase in the tooth germ, resulting in the slowdown of the tooth developmental pace. Our results provide compelling evidence that extrinsic signals can profoundly affect tooth developmental tempo, and the dental mesenchymal FGF8 could be a pivotal factor in controlling the developmental pace in a non-cell-autonomous manner during mammalian odontogenesis.

关键词： FGF8 Tooth Developmental pace Non-cell-autonomous

基于TLRs/MyD88信号通路探究温针灸干预兔膝骨性关节炎软骨退变机制

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甘肃中医药大学学报 2024年第1期41卷 1-7页

作者：吴琦阮金新陈朝霞吴福春余德标湄洲湾职业技术学院医学健康系福建建莆田351119 福建医科大学省立临床医学院福建省立医院康复医学科福建福州350001

目的基于Toll样受体(TLRs)/髓样分化因子88(MyD88)信号通路探究温针灸干预兔膝骨性关节炎(KOA)软骨退变的作用机制。方法将30只6月龄清洁级新西兰雄兔采用随机数字表法分为空白对照组、模型组、温针灸组3组,每组10只。除空白对照组外,其... 详细信息

目的基于Toll样受体(TLRs)/髓样分化因子88(MyD88)信号通路探究温针灸干预兔膝骨性关节炎(KOA)软骨退变的作用机制。方法将30只6月龄清洁级新西兰雄兔采用随机数字表法分为空白对照组、模型组、温针灸组3组,每组10只。除空白对照组外,其余2组通过木瓜蛋白酶关节腔注射建立KOA模型。实验干预后处死各组兔并取膝关节液和关节软骨组织,采用酶联免疫吸附试验(ELISA)法检测各组关节液中肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)的含量;采用HE染色镜下观察各组关节软骨病理改变,并比较关节软骨组织Mankin’s评分;采用TUNEL法检测关节软骨细胞凋亡情况,并比较各组软骨细胞凋亡率;通过免疫组化检测各组关节软骨Ⅱ型胶原蛋白表达水平,实时荧光定量聚合酶链式反应(qPCR)检测各组软骨细胞中TLR2、TLR4、MyD88、基质金属蛋白酶(MMP)-1、MMP-13 mRNA表达水平。结果HE染色镜下观察结果显示,空白对照组软骨层结构正常,潮线清晰完整;模型组软骨表面不光滑,有纤维组织形成,细胞排列无序、层次紊乱,潮线模糊;温针灸组较模型组明显改善,软骨表面不光滑,部分潮线模糊,表层软骨细胞较模型组增多。与空白对照组比较,模型组关节软骨组织Mankin’s评分,软骨细胞凋亡率,关节液中TNF-α、IL-1β含量,软骨细胞中TLR2、TLR4、MyD88、MMP-1、MMP-13 mRNA相对表达量明显升高,差异均有统计学意义(P<0.05);与模型组比较,温针灸组以上指标明显降低,差异均有统计学意义(P<0.05)。与空白对照组比较,模型组关节软骨Ⅱ型胶原蛋白相对表达量明显降低(P<0.05);与模型组比较,温针灸组关节软骨Ⅱ型胶原蛋白相对表达量明显升高(P<0.05)。结论温针灸可能是通过抑制TLRs/MyD88信号通路的激活,下调炎症因子TNF-α、IL-1β、MMP-1、MMP-13的表达水平,促进软骨细胞Ⅱ型胶原蛋白合成,从而抑制软骨细胞凋亡,延缓软骨退变,实现对KOA的治疗作用。

关键词：膝骨性关节炎温针灸 Toll样受体/髓样分化因子88信号通路炎症因子 Ⅱ型胶原蛋白软骨细胞凋亡率兔实验研究

补肾纳气中药对COPD大鼠膈肌细胞形态及相关肌细胞特异性microRNA下游指标的影响

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中国中医药现代远程教育 2024年第19期22卷 164-168页

作者：李大治阮诗玮王春娥张铃陈可强福建中医药大学附属第二人民医院呼吸科福建福州350003 福建中医药大学附属人民医院肾内科福建福州350004 福建中医药大学中西医结合研究院/福建省中西医结合老年性疾病重点实验室福建福州350122

目的探讨全真一气汤的作用机制及横膈在肾不纳气证形成中的意义。方法将80只SD大鼠按照随机数字表法分为六组,正常组(A组)10只、慢性阻塞性肺疾病(COPD)肾不纳气证组(B组)60只[模型组(B_(1)组)15只、中药实验组(B_(2)组)15只、中药对照... 详细信息

目的探讨全真一气汤的作用机制及横膈在肾不纳气证形成中的意义。方法将80只SD大鼠按照随机数字表法分为六组,正常组(A组)10只、慢性阻塞性肺疾病(COPD)肾不纳气证组(B组)60只[模型组(B_(1)组)15只、中药实验组(B_(2)组)15只、中药对照组(B_(3)组)15只、西药对照组(B_(4)组)15只]及COPD非肾不纳气证组(C组)10只,A组、B_(1)组大鼠给予氯化钠,B_(2)组给予全真一气汤,B_(3)组给予六君子汤,B_(4)组给予氨茶碱片,共60 d。HE染色观察A组、B_(1)组及C组的肺、膈肌病理形态,实时荧光定量聚合酶链式反应(qPCR)检测各组microRNA-1(以下简写为“miR-1”)、组蛋白去乙酰化酶4(HDAC4)及过氧化物酶体增殖物激活受体γ辅助因子1α(PGC-1α)表达,Western blot(WB)法检测以上指标的蛋白含量。结果B_(1)组膈肌纤维细胞排列紊乱、变形、间隙增宽,且重于C组。qPCR结果显示,其他各组miR-1表达皆低于A组(P<0.05),且B_(2)组、B_(4)组低于B_(1)组(P<0.05),B_(2)组低于B_(3)组(P<0.05);B_(2)组、B_(3)组和B_(4)组HDAC4表达高于B_(1)组,且B_(2)组HDAC4、PGC-1α表达皆高于B_(3)组(P<0.01),B_(1)组与C组HDAC4、PGC-1α表达差异均有统计学意义。WB结果显示,B_(2)组HDAC4蛋白表达高于B_(1)组和B_(3)组,PGC-1α蛋白表达高于B_(1)组、C组及B_(3)组、B_(4)组,C组PGC-1α蛋白表达高于B_(1)组。结论膈肌参与肾不纳气证的形成,全真一气汤可通过下调miR-1,影响HDAC4、PGC-1α的蛋白表达,改善COPD膈肌损伤。

关键词：慢性阻塞性肺疾病肾不纳气证细胞形态肌细胞特异性miRNAs 实验研究