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Development of a hybrid scaffold and a bioreactor for cartilage regeneration

Chinese Science Bulletin 2009年第19期54卷 3608-3612页

作者： LEE Seung-Jae LEE In Hwan PARK Jeong Hun GWAK So-Jung rhie jong-won CHO Dong-Woo KO Tae Jo KIM Dong Sung BK21 Mechatronics Group at Chungnam National University School of Mechanical Engineering Chungbuk National University DDS Research Lab. CKD Research Institute CKD Pharmaceutical Corp. Department of Plastic Surgery College of Medicine The Catholic University of Korea Department of Mechanical Engineering Pohang University of Science and Technology School of Mechanical Engineering Yeungnam University School of Mechanical Engineering Chung-Ang University

We developed a hybrid scaffold and a bioreactor for cartilage regeneration. The hybrid scaffold was developed as combination of two components: a biodegradable framework and hydrogel-containing chondrocytes. We performed the MTT cell proliferation assay to compare the proliferation and viability of chondrocytes on three types of scaffolds: an alginate gel, the hybrid scaffold, and an alginate sponge. Cells were encapsulated in 2% agarose gel. The bioreactor consisted of a circulation system and a compression system. We performed dynamic cell culture on these agarose gels in the bioreactor for 3 days.

关键词： MTT 生物分解凝解胶研究

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Early treadmill exercise increases macrophage migration inhibitory factor expression after cerebral ischemia/reperfusion

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Neural Regeneration Research 2019年第7期14卷 1230-1236页

作者： Min Cheol Chang Chae Ri Park Seung Hwa rhie Woo Hyun Shim Dae Yul Kim Department of Rehabilitation Medicine College of MedicineYeungnam University Asan Institute for Life Sciences Asan Medical CenterUniversity of Ulsan College of Medicine Department of Rehabilitation Medicine Asan Medical CenterUniversity of Ulsan College of Medicine Department of Radiology Asan Medical CenterUniversity of Ulsan College of Medicine

The neuroprotective function of macrophage migration inhibitory factor(MIF) in ischemic stroke was rarely *** study aimed to investigate the effects of early treadmill exercise on recovery from ischemic stroke and to determine whether these effects are associated with the expression levels of MIF and brain-derived neurotrophic factor(BDNF) in the ischemic area.A total of 40 male Sprague-Dawley rats were randomly assigned to the ischemia and exercise group [middle cerebral artery occlusion(MCAO)-Ex,n = 10),ischemia and sedentary group(MCAO-St,n = 10),sham-surgery and exercise group(Sham-Ex,n= 10),or sham-surgery and sedentary group(Sham-St,n = 10).The MCAO-Ex and MCAO-St groups were subjected to MCAO for 60 minutes,whereas the Sham-Ex and Sham-St groups were subjected to an identical operation without *** in the MCAO-Ex and Sham-Ex groups then ran on a treadmill for 30 minutes once a day for 5 consecutive *** reperfusion,the hanging time tested by the wire hang test was longer and the relative fractional anisotropy determined by MRI was higher in the peri-infarct region of the MCAO-Ex group compared with the MCAO-St *** expression levels of MIF and BDNF in the peri-infarct region were upregulated in the MCAO-Ex *** MIF and BDNF levels were positively correlated with relative fractional anisotropy changes in the peri-infarct *** was no significant difference in the levels of MIF and BDNF in the peri-infarct region between the Sham-Ex and Sham-St *** study demonstrated that early exercise(initiated 48 hours after the MCAO) could improve motor and neuronal recovery after ischemic ***,the increased levels of MIF and BDNF in the peri-infarct region(penumbra) may be one of the mechanisms of enhanced neurological function *** experiments were approved by the Institutional Animal Care and Use Committee in Asan Medical Center in South Korea(2016-12-126).

关键词： ischemic stroke early exercise macrophage migration inhibitory factor brain-derived neurotrophic factor motor recovery neural regeneration

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Amorphous FeZr metal for multi-functional sensor in electronic skin

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npj Flexible Electronics 2019年第1期3卷 64-71页

作者： Minhyun Jung Eunha Lee Dongseuk Kim Kyungkwan Kim Changjin Yun Hyangsook Lee Heegoo Kim Kungwon rhie Sanghun Jeon Department of Electrical Engineering Korea Advanced Institute of Science and TechnologyDaehak-Ro 291Yuseong-GuDaejeonRepublic of Korea Analytical Engineering Group Platform Technology LaboratorySamsung Advanced Institue of TechnologySuwon 16678Republic of Korea Spin Convergence Research Team Korea Research Institute of Standards and ScienceDaejeon 34113Republic of Korea Department of Applied Physics Korea UniversitySejong 30019Republic of Korea

The composition of an amorphous metal,which is well known for having no slip plane or slip direction,can be tailored for enhanced strength and a lower Young’s modulus under mechanical *** crystalline metals,elastic amorphous metals can,in principle,be used as a flexible electrode in soft,wearable electronics.A metal with a lattice structure absorbs external energy,which causes structural deformations,while an amorphous metal does not absorb ***,amorphous metals have excellent mechanical properties that can overcome the limitations of crystalline ***,voids inside such metals are easily formed according to Thornton’s model,which results in the formation of mesoporous(10–50 nm)rods due to the spatial separation of metal *** eliminated the porosity in amorphous metals by controlling the kinetic energy of sputtered metal atoms and *** Fe_(33)Zr_(67) has an amorphous structure with a strength of 2.88 GPa and a Young’s modulus of 76.6 *** this amorphous metal,we fabricated a stretchable and multi-functional sensor for electronic skin that enables the detection of pressure,temperature and light and also serves as a *** this work,we demonstrate the feasibility of the amorphous metal Fe33Zr67 in soft electronics for use in various industrial applications.

关键词： amorphous metals electronic

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Effect of Coal Gases on Electrochemical Reactions in the Direct Carbon Fuel Cell System

Effect of Coal Gases on Electrochemical Reactions in the Dir...

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作者： Seongyong Eom Seongyool Ahn Younghoon rhie Gyungmin Choi Duckjool Kim Graduation School of Mechanical Engineering Pusan National University Pusan National University CRIEPI Japan School of Mechanical Engineering Pusan National University

Various carbonaceous fuels were evaluated in a Direct Carbon Fuel Cell(DCFC) system as energy *** order to investigate the characteristics of electrochemical reaction of various fuels in DCFC,three coals,such as Shenhua coal,Adaro coal,and Openblue coal which have different content of fixed carbon and volatile matter,were selected in this *** characteristics of electrochemical reactions of fuels were investigated at 700℃ by potentiostatic method of the fuel cell and the effect of fuels properties is also *** effect of gases from coals was investigated by using raw coal state and char state in present *** gases,such as H,CH,CO and CO,were detected in the exhaust gas of anode side by thermal decomposition of *** is confirmed that these gases have an effect on the electrochemical reaction on DCFC system by comparing of current density of raw coal and char.

关键词： Direct carbon fuel cell coal fuel gasification volatile matter

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浅析现代住宅生活风格设计——以韩国三星样板住宅生活风格设计为对象

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临沂大学学报 2013年第4期35卷 103-105页

作者：曾淼李珍旼韩国淑明女子大学校生活风格设计研究院韩国首尔140742

韩国与中国一衣带水,同属于东亚国家,人们对审美有着相似的感受,这也为本文研究两国现代生活风格设计提供了基础。韩国现代公寓住宅生活风格设计发展较早,理论与实践方面也较为成熟,所以韩国住宅生活风格设计可以为中国的此类设计提供... 详细信息

韩国与中国一衣带水,同属于东亚国家,人们对审美有着相似的感受,这也为本文研究两国现代生活风格设计提供了基础。韩国现代公寓住宅生活风格设计发展较早,理论与实践方面也较为成熟,所以韩国住宅生活风格设计可以为中国的此类设计提供一定的学习和借鉴。通过中韩两国样板住宅的发展历史以及生活风格设计的概念,对韩国三星样板住宅进行浅析,说明韩国在生活风格设计中的手段与特点。希望文章可以为今后中韩两国生活风格设计的交流发展和学习提供参考,为进一步推进中国生活风格设计向精细化发展并且符合中国国情的住宅生活风格设计方法,将中国生活风格设计提高到一个新台阶!

关键词：中国韩国样板住宅生活风格设计

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