检索结果-南通市图书馆

Targeting brain tumors with innovative nanocarriers:bridging the gap through the blood-brain barrier

Oncology Research 2024年第5期32卷 877-897页

作者： KARAN WADHWA PAYAL CHAUHAN SHOBHIT KUMAR RAKESH PAHWA RAVINDER VERMA rajat goyal GOVIND SINGH ARCHANA SHARMA NEHA RAO DEEPAK KAUSHIK Department of Pharmaceutical Sciences Maharshi Dayanand UniversityRohtak124001India Department of Pharmaceutical Technology Meerut Institute of Engineering and Technology(MIET)NH-58Delhi-Roorkee HighwayMeerut250005India Institute of Pharmaceutical Sciences Kurukshetra UniversityKurukshetra136119India Department of Pharmaceutical Sciences Chaudhary Bansi Lal UniversityBhiwani127021India MM College of Pharmacy Maharishi Markandeshwar(Deemed to be University)Mullana-AmbalaHaryana133207India Delhi Pharmaceutical Sciences and Research University(DIPSAR) Delhi Pharmaceutical Sciences and Research UniversityNew Delhi110017India

Background:Glioblastoma multiforme(GBM)is recognized as the most lethal and most highly invasive *** high likelihood of treatment failure arises fromthe presence of the blood-brain barrier(BBB)and stemcells around GBM,which avert the entry of chemotherapeutic drugs into the ***:Recently,several researchers have designed novel nanocarrier systems like liposomes,dendrimers,metallic nanoparticles,nanodiamonds,and nanorobot approaches,allowing drugs to infiltrate the BBB more efficiently,opening up innovative avenues to prevail over therapy problems and radiation ***:Relevant literature for this manuscript has been collected from a comprehensive and systematic search of databases,for example,PubMed,Science Direct,Google Scholar,and others,using specific keyword combinations,including“glioblastoma,”“brain tumor,”“nanocarriers,”and several ***:This review also provides deep insights into recent advancements in nanocarrier-based formulations and technologies for GBM *** of various scientific advances in conjunction with encouraging findings concerning the future perspectives and challenges of nanocarriers for effective brain tumor management has also been discussed.

关键词： Glioblastoma Brain tumor Blood-brain barrier Liposomes Metallic nanoparticles Nanocarriers

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insights on the Emerging Therapeutic Potential of Terpenoids as Anti-inflammatory Agents:A Scoping Review

引用

Journal of Bio-X Research 2024年第1期7卷 20-35页

作者： Mohini Devi Prabhjeet Kaur Bamrah rajat goyal Manjusha Choudhary Hitesh Chopra Institute of Pharmaceutical Sciences Kurukshetra UniversityKurukshetra 136119HaryanaIndia MM College of Pharmacy Maharishi Markandeshwar(Deemed to be University)Mullana-Ambala 133207HaryanaIndia Department of Biosciences Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesChennai 602105Tamil NaduIndia

Background:Inflammatory diseases are among the leading causes of health issues that considerably influence health care *** the notable advancements in medical treatment that have been made in recent years,natural products with biological activity still play essential roles in a variety of anti-inflammatory *** study and identification of novel treatments for the adverse effects of available synthetic anti-inflammatory agents warrant further ***:This study focused on the emerging therapeutic potential of terpenoid products as anti-inflammatory ***:The literature reveals that secondary metabolites obtained from medicinal plants,*** and terpenoids and their nanoformulations,are effective for the treatment of inflammation in *** terpenes are a broad class of secondary metabolites that are rich in monoterpenes,diterpenes,triterpenes,tetraterpenes,ceramides,and sesquiterpenes and have various therapeutic applications,such as antitumor,antibacterial,antimicrobial,analgesic and anti-inflammatory *** studies have shown that terpenes can decrease inflammation-associated symptoms by reducing the release of proinflammatory cytokines,including nuclear transcription factor-kappa B,interleukins,tumor necrosis factor-alpha,and other inflammatory ***:This review describes the latest knowledge of the different terpenoid-derived natural and synthetic compounds that have been isolated from plant sources in recent years and their anti-inflammatory potential and therapeutic mechanism of ***,this study focused on terpenoid-based nanoformulations with enhanced bioavailability and improved therapeutic efficacy as anti-inflammatory agents.

关键词： conditions. formulation considerably

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Insights from a Brief Study of Renal Calculi:Recent Diagnostic and Treatment Approaches

引用

Journal of Bio-X Research 2024年第1期7卷 8-19页

作者： Aashish Kumar rajat goyal Kajal Garg Sumeet Gupta Kashish Wilson Hitesh Chopra MM College of Pharmacy Maharishi Markandeshwar(Deemed to be University)Mullana-AmbalaHaryana 133207India Lal Chand Mal College of Education JhansaKurukshetraHaryana 136130India Department of Biosciences Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesChennaiTamil Nadu 602105India

Background:Renal calculi,commonly known as kidney stones,is a prevalent urological condition that affects a substantial portion of the population *** formation of kidney stones is a complex process influenced by various factors,including diet,fluid intake,genetics,and metabolic *** pathogenesis of renal calculi involves a complex interplay of multiple factors,including supersaturation of urine with stone-forming constituents,urinary supersaturation,crystallization,and ***:This review aims to provide an overview of the present understanding of renal calculi,their pathophysiology,diagnostic approaches,and available treatment ***:This review discusses the different types of kidney stones,such as calcium oxalate,calcium phosphate,uric acid,and struvite stones,and explores their formation mechanisms and associated risk *** management of renal calculi relies on stone characteristics,patient symptoms,stone size,and ***,counseling and education regarding lifestyle modifications and risk factor management are essential for long-term ***:Accurate diagnosis and appropriate management based on stone characteristics and patient symptoms are essential for successful *** strategies to reduce stone recurrence are vital for long-term management and patient ***,further research is needed to refine diagnostic techniques,improve treatment options,and enhance the understanding of the underlying pathophysiology of renal calculi.

关键词： diagnosis urine treatment

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：