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Astrophysical s-factor and reaction rate for 15N(p,γ)16O within the modified potential cluster model

Chinese Physics C 2024年第4期48卷 130-145页

作者： s.B.Dubovichenko A.s.Tkachenko r.Ya.Kezerashvili N.A.Burkova B.M.Yeleusheva Fesenkov Astrophysical Institute 050020 AlmatyKazakhstan New York City College of Technology City University of New YorkBrooklyn11201 New YorkUSA Graduate school and University Center City University of New York10016 New YorkUSA al-Farabi Kazakh National University 050040 AlmatyKazakhstan

We study radiative p^(15)N capture on the ground state of ^(16)O at stellar energies within the framework of a modified potential cluster model(MPCM)with forbidden states,including low-lying *** investigation of the ^(15)N(p,γ0)^(16)O reaction includes the consideration of ^(3)s_(1) resonances due to E1 transitions and the contribution of the ^(3)P_(1) scattering wave in the p+^(15)N channel due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the astrophysical low-energy s-factor,and the extrapolated s(0)turned out to be within 34.7−40.4 keV·*** important role of the asymptotic constant(AC)for the ^(15)N(p,γ0)16O process with interfering ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances is elucidated.A comparison of our calculation for the s-factor with existing experimental and theoretical data is addressed,and a reasonable agreement is *** reaction rate is calculated and compared with the existing *** has negligible dependence on the variation of AC but shows a strong impact of the interference of ^(3)s_(1)(312)and ^(3)s_(1)(962)resonances in reference to the CNO Gamow windows,especially at low *** estimate the contribution of cascade transitions to the reaction rate based on the exclusive experimental data from ***.C.85,065810(2012).The reaction rate enhancement due to the cascade transitions is observed from T_(9)>0.3 and reaches the maximum factor~1.3 at T_(9)=*** present the Gamow energy window and a comparison of rates for radiative proton capture reactions ^(12)N(p,γ)^(13)O,^(13)N(p,γ)^(14)O,^(14)N(p,γ)^(15)O,and ^(15)N(p,γ)^(16)O obtained in the framework of the MPCM and provide the temperature windows,prevalence,and significance of each process.

关键词： low and astrophysical energies p^(15)N system thermonuclear reaction rate potential cluster model CNO-cycle

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s1P: the elixir of life for naive T cells

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Cellular & Molecular Immunology 2018年第7期15卷 657-659页

作者： Michaël Pérès Anne Montfort Nathalie Andrieu-Abadie Céline Colacios Bruno ségui INsErM UMr1037 Centre de Recherches en Cancérologie de ToulouseToulouse 31037France Facultéde pharmacie UniversitéToulouse III Paul-SabatierToulouse 31062France Laboratoire d’hématologie CHU de ToulouseToulouse 31059France Equipe Labellisée Ligue Contre Le Cancer Toulouse 31037France Correspondence:Professor B SéguiPhDINSERMUMR1037 CRCTCentre de Recherches en Cancérologie de Toulouse2 avenue Hubert CurienToulouse 31037France

During their life,T cells are constantly circulating throughout the ***-1-phosphate(s1P),a sphingolipid metabolite,triggers T cell egress from the thymus and secondary lymphoid organs(sLO)into the lymph and the *** phenomenon is dependent on the s1P gradient between lymphoid organs(including thymus and sLO)and the lymphatic and blood vessels,which exhibit low,intermediate and high s1P levels,respectively.T cells follow the s1P gradient via the engagement of the G-protein-coupled receptor s1P receptor 1(s1P1)expressed on T cells.1 s1P production is regulated by various sphingolipid-metabolizing *** sphingosine kinases 1 and 2(sKs),encoded by sphk1 and sphk2,phosphorylate the sphingosine(sph)into ***,s1P can be dephosphorylated to sph by s1P phosphatases 1 and 2,encoded by sgpp1 and ***,s1P can be irreversibly degraded by the s1P Lyase(sPL),encoded by sgpl1,into phosphoethanolamine and hexadecenal.

关键词： organs al. lymphoid

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An Efficient Accurate Direct solution of Poisson's Equation for Computation of Meteorological Parameters

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Advances in Atmospheric sciences 1989年第4期6卷 501-508页

作者： D.r.Chakraborty P.s.salvekar Indian Institute of Tropical Meteorology Pune-411005IndiaIndian Institute of Tropical MeteorologyPune-411005India

Poisson's equation is solved numerically by two direct methods, viz. Block Cyclic reduction (BCr) method and Fourier Method. Qualitative and quantitative comparison between the numerical solutions obtained by two methods indicates that BCr method is superior to Fourier method in terms of speed and accuracy. Therefore. BCr method is applied to solve (?)2(?)= ζ and (?)2X= D from observed vorticity and divergent values. Thereafter the rotational and divergent components of the horizontal monsoon wind in the lower troposphere are reconstructed and are com pared with the results obtained by successive Over-relaxation (sOr) method as this indirect method is generally in more use for obtaining the streamfunction ((?)) and velocity potential (X) fields in NWP models. It is found that the results of BCr method are more reliable than sOr method.

关键词： An Efficient Accurate Direct solution of Poisson’s Equation for Computation of Meteorological Parameters

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The adsorptive properties of UiO-66 towards organic dyes: A record adsorption capacity for the anionic dye Alizarin red s.

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Chinese Journal of Chemical Engineering 2018年第4期26卷 731-739页

作者： Marwa s.Embaby saber D.Elwany Widiastuti setyaningsih Mohamed r.saber Central laboratories Fayoum Drinking Water and Sanitation Company (FDWaSC) Food and Agricultural Product Technology Department Faculty of Agricultural Technology Gadjah Mada University Chemistry Department Faculty of Science Fayoum University

In order to decisively determine the adsorption selectivity of zirconium MOF(UiO-66) towards anionic versus cationic species, the adsorptive removal of the anionic dyes(Alizarin red s.(Ars), Eosin(E), Fuchsin Acid(FA)and Methyl Orange(MO)) and the cationic dyes(Neutral red(Nr), Fuchsin Basic(FB), Methylene Blue(MB),and safranine T(sT)) has been evaluated. The results clearly reveal a significant selectivity towards anionic dyes. such an observation agrees with a plethora of reports of UiO-66 superior affinity towards other anionic species(Floride, PO_4^(3-), Diclofenac sodium, Methylchlorophenoxy-propionic acid, Phenols, CrO_4^(2-), seO_3^(2-), and AsO_4^-). The adsorption process of Ars as an example has been optimized using the central composite design(CCD). The resultant statistical model indicates a crucial effect of both pH and sorbent mass. The optimum conditions were determined to be initial dye concentration 11.82 mg.L^(-1), adsorbent amount 0.0248 g, shaking time of 36 min and pH 2. The adsorption process proceeds via pseudo-second order kinetics(r^2= 0.999). The equilibrium data were fit to Langmuir and Tempkin models(r^2= 0.999 and 0.997 respectively). The results reveal an exceptional removal for the anionic dye(Alizarin red s.) with a record adsorption capacity of400 mg·g^(-1). The significantly high adsorption capacity of UiO-66 towards Ars adds further evidence to the recently reported exceptional performance of MOFs in pollutants removal from water.

关键词： Adsorption Metal-organic frameworks Alizarin red s. Dye removal UiO-66 Central composite design

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Mycobacterium avium subspecies paratuberculosis causes Crohn's disease in some inflammatory bowel disease patients

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World Journal of Gastroenterology 2014年第23期20卷 7403-7415页

作者： saleh A Naser sudesh r sagramsingh Abed s Naser saisathya Thanigachalam Burnett school of Biomedical sciences College of MedicineUniversity of Central FloridaOrlandoFL 32816United States

Crohn’s disease(CD)is a chronic inflammatory condition that plagues millions all over the *** debilitating bowel disease can start in early childhood and continue into late *** and symptoms are usually many and multiple tests are often required for the diagnosis and confirmation of this ***,little is still understood about the cause(s)of *** a result,several theories have been proposed over the *** theory in particular is that Mycobacterium avium subspecies paratuberculosis(MAP)is intimately linked to the etiology of *** fastidious bacterium also known to cause Johne’s disease in cattle has infected the intestines of animals for *** is believed that due to the thick,waxy cell wall of MAP it is able to survive the process of pasteurization as well as chemical processes seen in irrigation purification *** meat,dairy products and water serve as key vehicles in the transmission of MAP infection to humans(from farm to fork)who have a genetic predisposition,thus leading to the development of *** challenges faced in culturing this bacterium from CD are *** include its extreme slow growth,lack of cell wall,low abundance,and its mycobactin *** this review article,data from 60 studies showing the detection and isolation of MAP by PCr and culture techniques have been *** this review may not be 100%comprehensive of all studies,clearly the majority of the studies overwhelmingly and definitively support the role of MAP in at least30%-50%of CD *** is very possible that lack of detection of MAP from some CD patients may be due to the absence of MAP role in these *** latter statement is conditional on utilization of methodology appropriate for detection of human MAP ***,stratification of CD and inflammatory bowel disease patients for the presence or absence of MAP is necessary for appropriate and effective treatment which may lead to a cure.

关键词： Mycobacterium paratuberculosis Crohn's disease Culture PCr Johne's disease Inflammatory bowel disease

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Field-dependent resistive transitions in YBa_2Cu_3O_(7-δ) thin films:Influence of the pseudogap on vortex dynamics

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Chinese Physics B 2015年第1期24卷 467-473页

作者： s H Naqib r s Islam Department of Physics University of RajshahiRajshahi-6205 Bangladesh

The nature of resistive transition of high-quality crystalline thin films of YBa2Cu3O7-δhas been studied under magnetic fields（H） applied along the c direction over a wide range of doped holes, p, in the Cu O2 planes. The field- and temperature-dependent in-plane resistivity, ρab（T, H）, has been analyzed within the thermally assisted flux-flow（TAFF）formalism. The flux activation energy, U（T, H）, has been extracted from this analysis. The low-T part of the ρab（T, H）data can be described by an activation energy having the functional form of U（T, H） =（1- t）m（H-0/H）β, where t = T /Tc（reduced temperature）, and H0 is a field scale that primarily determines the magnitude of U（T, H）. The temperature exponent, m, shows a systematic variation with p, whereas the field exponent, β, is insensitive to the p values and is close to unity. The H0, on the other hand, changes rapidly as p is varied. U（T, H） is linked to the pinning potential and consequently on the superconducting condensation energy. since the normal state pseudogap directly affects superconducting condensation energy, a clear correspondence between H0 and the PG energy scale, ε g, is found. Possible implications of these results are discussed.

关键词： Y123 superconductors thermally assisted flux-flow model activation energy pseudogap

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Nucleoside modified mrNA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord

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Neural regeneration research 2025年第8期20卷 2311-2312页

作者： Krisztián Pajer Tamás Bellák Antal Nógrádi Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

spinal cord injury and treatment opportunities:The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular *** the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(Khyeam et al.,2021).

关键词： injured capacity modified

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A semi-supervised hierarchical approach： two-dimensional clustering of microarray gene expression data

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Frontiers of Computer science 2013年第2期7卷 204-213页

作者： r PrIsCILLA s sWAMYNATHAN Department of Information and science and Technology The College of Engineering Guindy Campus Anna UniversityIndia Chennai 600025

Micro array technologies have become a widespread research technique for biomedical researchers to assess tens of thousands of gene expression values simul- taneously in a single experiment. Micro array data analysis for biological discovery requires computational tools. In this research a novel two-dimensional hierarchical clustering is presented. From the review, it is evident that the previous research works have used clustering which have been ap- plied in gene expression data to create only one cluster for a gene that leads to biological complexity. This is mainly because of the nature of proteins and their interactions. since proteins normally interact with different groups of proteins in Order to serve different biological roles, the genes that produce these proteins are therefore expected to co express with more than one group of genes. This constructs that in micro array gene expression data, a gene may makes its pres- ence in more than one cluster. In this research, multi-level micro array clustering, performed in two dimensions by the proposed two-dimensional hierarchical clustering technique can be used to represent the existence of genes in one or more clusters consistent with the nature of the gene and its attributes and prevent biological complexities.

关键词： clustering hierarchical clustering supervisedclustering overlapping clustering

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Chemical expansion of solid oxide fuel cell materials: A brief overview

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Acta Mechanica sinica 2013年第3期29卷 312-317页

作者： s.r.Bishop International Institute for Carbon Neutral Energy research Kyushu University

The importance of oxygen non-stoichiometry induced expansion, known as chemical expansion, for the mechanical properties of solid oxide fuel cells （sOFCs） is discussed. The methods used to measure chemical expansion and the defects responsible for its existence are introduced. recent work demonstrating the origin of chemical expansion in fluorite structured oxides for sOFCs is presented. Models used to predict stress induced by chemical expansion in sOFCs, highlighting the necessity of considering electro-chemo-mechanical coupling relationships, are discussed.

关键词： Defect equilibria · sOFC mechanical properties · Chemical expansion

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remembering your A, B, C’s: Alzheimer’s disease and ABCA1

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Acta Pharmaceutica sinica B 2022年第3期12卷 995-1018页

作者： Cutler T.Lewandowski Megan s.Laham Gregory r.J.Thatcher Department of Pharmaceutical sciences University of Illinois College of PharmacyChicagoIL 60612USA Department of Pharmacology and Toxicology University of Arizona College of PharmacyTucsonAZ 85721USA

The function of ATP binding cassette protein A1(ABCA1)is central to cholesterol *** ABCA1 expression or activity is implicated in Alzheimer’s disease(AD)and other *** approaches to boost ABCA1 activity have yet to be translated successfully to the *** risk factors for AD development and progression,including comorbid disorders such as type2 diabetes and cardiovascular disease,highlight the intersection of cholesterol transport and *** of ABCA1 can positively impact APOE lipidation,insulin sensitivity,peripheral vascular and blood-brain barrier integrity,and anti-inflammatory *** strategies towards ABCA1-boosting compounds have been described,with a bias toward nuclear hormone receptor(NHr)*** agonists display beneficial preclinical effects;however,important side effects have limited *** particular,ligands that bind liver X receptor(LXr),the primary NHr that controls ABCA1 expression,have shown positive effects in AD mouse models;however,lipogenesis and unwanted increases in triglyceride production are often *** longstanding approach,focusing on LXrβ*** selectivity,is over-simplistic and has *** approaches such as phenotypic screening may lead to small molecule NHr modulators that elevate ABCA1 function without inducing lipogenesis and are clinically translatable.

关键词： Alzheimer’s disease Cardiovascular disease Cholesterol Drug discovery Liver X receptor Nuclear hormone receptor Type 2 diabetes

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