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Using state space models as a statistical impact measurement of survey redesigns: a case study of the labour force survey of the Australian Bureau of Statistics

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Statistical Theory and related Fields 2019年第2期3卷 224-238页

作者： Xichuan(Mark)Zhang Jan A.van den Brakel Siu-Ming Tam Methodology Division Australian Bureau of Statistics(ABS)CanberraAustralia Department of Statistical Methods Statistics Netherlands and Department of Quantitative EconomicsMaastricht University School of Business and EconomicsCanberraAustralia National Institute for Applied Statistics research Australia University of WollongongCanberraAustralia

The goals of any major business transformation programme in an official statistical agency often include improving data collection efficiency,data processing methodologies and data ***,the achievement of such improvements may have transitional statistical impacts that could be misinterpreted as real-world changes if they are not measured and handled *** paper describes a development work that sought to explore the design and analysis of a times-series experiment that measured the statistical impacts that sometimes occur during survey *** Labour Force Survey(LFS)of the Australian Bureau of Statistics(ABS)was used as a case *** the present study:(1)A large-scale field experiment was designed and conducted that allowed the outgoing and the incoming surveys to run in parallel for some periods to measure the impacts of any changes to the survey process;and(2)The precision of the impact measurement was continuously improved while the new survey design was being *** state space modelling(SSM)technique was adopted as the main approach,as it provides an efficient impact *** approach enabled sampling error structure to be incorporated in the time-series intervention *** approach was also able to be extended to take advantage of the availability of other related data sources(e.g.,the data obtained from the parallel data collection process)to improve the efficiency and accuracy of the impact *** stated above,the LFS was used as a case study;however,the models and methods developed in this study could be extended to other surveys.

关键词： Intervention analysis survey sampling structural time series modelling labour force survey Kalman filter

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A 3D In-vitro model of the human dentine interface shows long-range osteoinduction from the dentine surface

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International Journal of Oral Science 2024年第2期16卷 225-237页

作者： William Macalester Asme Boussahel rafael O.Moreno-Tortolero Mark r.Shannon Nicola West Darryl Hill Adam Perriman School of Cellular and Molecular Medicine Biomedical Sciences BuildingUniversity of BristolUniversity WalkBristolUnited Kingdom Bristol Centre for Functional Nanomaterials HH Wills Physics LaboratoryUniversity of BristolTyndall AvenueBristolUnited Kingdom Centre for Protolife research School of ChemistryUniversity of BristolCantocks CloseBristolUnited Kingdom Max Planck-Bristol Centre for Minimal Biology School of ChemistryUniversity of BristolBristolUnited Kingdom Periodontology Bristol Dental SchoolUniversity of BristolLower Maudlin StreetBristolUnited Kingdom

Emerging regenerative cell therapies for alveolar bone loss have begun to explore the use of cell laden hydrogels for minimally invasive surgery to treat small and spatially complex maxilla-oral ***,the oral cavity presents a unique and challenging environment for in vivo bone tissue engineering,exhibiting both hard and soft periodontal tissue as well as acting as key biocenosis for many distinct microbial communities that interact with both the external environment and internal body systems,which will impact on cell fate and subsequent treatment ***,we design and bioprint a facile 3D in vitro model of a human dentine interface to probe the effect of the dentine surface on human mesenchymal stem cells(hMSCs)encapsulated in a microporous hydrogel *** demonstrate that the dentine substrate induces osteogenic differentiation of encapsulated hMSCs,and that both dentine andβ-tricalcium phosphate substrates stimulate extracellular matrix production and maturation at the gel-media interface,which is distal to the gel-substrate *** findings demonstrate the potential for long-range effects on stem cells by mineralized surfaces during bone tissue engineering and provide a framework for the rapid development of 3D dentine-bone interface models.

关键词： interface den surface

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Diversity and delimitation of rhizopus microsporus

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Fungal Diversity 2014年第1期64卷 145-163页

作者： Somayeh Dolatabadi Grit Walther A.H.G.Gerrits van den Ende G.S.de Hoog CBS-KNAW Fungal Biodiversity Centre P.O.Box 851673508 AD UtrechtThe Netherlands Institute for Biodiversity and Ecosystem Dynamics University of AmsterdamAmsterdamThe Netherlands Institute of Microbiology Department of Microbiology and Molecular BiologyUniversity of JenaJenaGermany Leibniz-Institute for Natural Product research and Infection Biology-Hans-Knöll-Institute Jena Microbial Resource CollectionJenaGermany research Center for Medical Mycology Peking University Health Science CenterBeijingChina Sun Yat-sen Memorial Hospital Sun Yat-sen UniversityGuangzhouChina Shanghai Institute of Medical Mycology Changzheng HospitalSecond Military Medical UniversityShanghaiChina

rhizopus microsporus has been used for centuries in the production of oriental fermented foods,but the species is also known as a toxin producer and from severe human *** study the diversity and species delimitation of rhizopus microsporus,48 isolates from the reference collection of the CBS-KNAW Fungal Biodiversity Centre,comprising nine environmental,ten clinical,and 23 foodborne strains,in addition to six strains from unknown sources and representing all existing varieties of the species,were *** diversity was based on the internal transcribed spacer(ITS),and on a part of the actin(ACT)and translation elongation factor 1-α(TEF)*** in physiological properties were assessed including temperature *** morphology was studied,mating type tests were performed,and MALDI-ToF profiles were *** and food-associated strains as well as members of different varieties mated successfully and consequently they belong to a single biological *** differences did not match with any other parameter *** on these results the varieties of rhizopus microsporus are reduced to synonyms.

关键词： rhizopus microsporus Phylogeny Taxonomy Physiology MALDI-ToF Mating type Foodborne fungi Medical mycology Sporulation

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Unusual high-density and saline aqueous inclusions in ultrahigh pressure metamor- phic rocks from Sulu terrane in eastern China

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Chinese Science Bulletin 2003年第18期48卷 2018-2023页

作者： SHEN Kun ZHANG Zeming A.M.van den Kerkhof XIAO Yilin XU Zhiqin J.Hoefs Institute of Geological Sciences of Shandong Jinan 250013China Institute of Geology CAGSBeijing 100037China Geoscience Center University GttingenGttingen 37077Germany

Primary high-density fluid inclusions were identified in garnet from ultrahigh pressure eclogite in the southern part of the Sulu terrane. They occur isolatedly or in cluster together with relatively low-density two-phase inclu-sions. The eutectic temperature of the inclusions is as low as ≤ -52℃. A bubble was nucleated in a liquid inclusion dur-ing the specific stage of cyclic cooling-heating runs, and the liquid-gas homogenization temperature was measured to be ≤-12.5℃. The composition of the inclusions modeled by the system CaCl2-NaCl-H2O, yields the fluid density of 1.27g/cm3 that corresponds to a pressure of ca. 2.4 GPa at thetemperature of peak eclogite-facies metamorphism, close tothe ultrahigh pressure metamorphic conditions. During theexhumation of the eclogite the inclusions reacted with thehost mineral, forming hydrous silicate minerals that resulted in lowering of the fluid density and its transformation to multi-phase inclusions.

关键词： ultrahigh pressure eclogite fluid inclusion microther-mometry isochore P-T path.

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Phylogeny of the industrial relevant,thermophilic genera Myceliophthora and Corynascus

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Fungal Diversity 2012年第1期52卷 197-207页

作者： Joost van den Brink robert A.Samson Ferry Hagen Teun Boekhout ronald P.de Vries CBS-KNAW Fungal Biodiversity Centre P.O.Box 851673508 AD UtrechtThe Netherlands

Species of the genus Myceliophthora and its teleomorph Corynascus have attracted increasing interest due to their potential to produce thermostable *** study re-assessed the phylogenetic relationship of 49 isolates of nine species belonging to Myceliophthora and *** species,***,was shown not to belong to the genus Myceliophthora and should be placed in the genus *** other species belonged to two phylogenetic clusters:mesophilic fungi with the type species *** and ***,and thermophilic fungi with ***,*** and *** phylogenetic data provides no clear separation of the two genera Corynascus and *** avoid confusion in future taxonomic studies,it is proposed that all existing Corynascus species be renamed to Myceliophthora,which is the old name and the one more frequently ***,this study identified two groups within the isolates listed as *** and assigned one group(five isolates)to *** based on AFLP analysis and mating *** study provides new insights into the genetic differences within the genus Myceliophthora and will therefore be essential for the interpretation of future genomic and physiological studies of these species.

关键词： Myceliophthora Corynascus Thermophiles M.heterothallica M.thermophila.Thermophilic fungi Multigene phylogeny AFLP analysis Mating behavior

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Sucrose Induction of Anthocyanin Biosynthesis Mediated by DELLA

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Molecular Plant 2014年第3期7卷 570-572页

作者： Yi Li Wire van den Ende Filip rolland Laboratory of Molecular Plant Biology KU Leuven Department of Biology Kasteelpark Arenberg 31 B-3001 Leuven Belgium

Dear Editor, While they affect all aspects of plant life, the exact molecu- lar mechanisms involved in sugar sensing and signaling are still mostly unknown. However, using the induction of antho- cyanin biosynthesis as a convenient readout and tool, the DELLA proteins can be identified as key positive regulators in sucrose-specific signaling and a point of integration of diverse metabolic and hormonal signals.

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Counting the SNArEs needed for membrane fusion

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分子细胞生物学报:英文版 2011年第4期3卷 204-205页

作者： Geert van den Bogaart reinhard Jahn Department of Neurobiology Max-Planck Institute for Biophysical ChemistryAm Fassberg 1137077 GottingenGermany

SNArE proteins mediate most membrane fusion reactions in eukaryotic cells,and are thereby vital for many functions,including synaptic transmission,cell growth,and ***,until recently it was still unclear how many of these proteins are required to catalyze membrane fusion in *** a recent Science paper,Mohrmann et al.(2010)elegantly show that in chromaffin cells,three SNArE complexes are required for the synchronous release of granules,whereas only a single SNArE complex is sufficient for overall release.

关键词： release thereby complexes

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Azathioprine does not reduce adenoma formation in a mouse model of sporadic intestinal tumorigenesis

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World Journal of Gastroenterology 2014年第44期20卷 16683-16689页

作者： Mattheus CB Wielenga Jooske F van Lidth de Jeude Sanne L rosekrans Alon D Levin Monique Schukking Geert rAM D'Haens Jarom Heijmans Marnix Jansen vanesa Muncan Gijs r van den Brink Tytgat Institute for Liver and Intestinal research and Department of Gastroenterology and Hepatology Academic Medical Center Department of Pathology Academic Medical Center

AIM: To investigate if azathioprine could reduce adenoma formation in ApcMin/+, a mouse model of sporadic intestinal tumorigenesis.

关键词： Azathioprine Thiopurine Intestinal adenoma Polyp ApcMin Chemoprevention Lymphoma Colon cancer

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risk factors for overuse injuries in short-and long-distance running: A systematic review

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Journal of Sport and Health Science 2021年第1期10卷 14-28,I0001页

作者： dennis van Poppel Maarten van der Worp Anouk Slabbekoorn Sylvia S.P.van den Heuvel Marienke van Middelkoop Bart W.Koes Arianne P.Verhagen Gwendolyne G.M.Scholten-Peeters research Group Diagnostics Avans University of Applied SciencesBreda4818 CRthe Netherlands Stichting Academie Instituut Fysiotherapie PLUS Utrecht3581 MDthe Netherlands Nederlands Paramedisch Institute Amersfoort3818 LAthe Netherlands Department of General Practice Erasmus MC Medical University CenterRotterdam3015 CEthe Netherlands Center for Muscle and Joint Health University of Southern DenmarkOdense5230Denmark Discipline of Physiotherapy Graduate School of HealthUniversity of TechnologySydneyChippendale NSW 2008Australia Department of Human Movement Sciences Faculty of Behavioral and Movement SciencesVrije Universiteit AmsterdamAmsterdam1081 HVthe Netherlands

Purpose:The aim of this study was to review information about risk factors for lower extremity running injuries in both short-distance(mean running distance-20 km/week and-10 km/session)and long-distance runners(mean running distance>20 km/week and>10 km/session).Methods:Electronic databases were searched for articles published up to February *** cohort studies using multivariable analysis for the assessment of individual risk factors or risk models for the occurrence of lower extremity running injuries were *** reviewers independently selected studies for eligibility and assessed risk of bias with the Quality in Prognostic Studies *** GrADE approach was used to assess the quality of the ***:A total of 29 studies were included:17 studies focused on short-distance runners,11 studies focused on long-distance runners,and 1 study focused on both types of runners.A previous running-related injury was the strongest risk factor for an injury for long-distance runners,with moderate-quality *** injuries not attributed to running was the strongest risk factor for an injury for short-distance runners,with high-quality *** body mass index,higher age,sex(male),having no previous running experience,and lower running volume were strong risk factors,with moderate quality evidence,for short-distance ***-quality evidence was found for all risk models as predictors of runningrelated injuries among short-and long-distance ***:Several risk factors for lower extremity injuries have been identified among short-and long-distance runners,but the quality of evidence for these risk factors for running-related injuries is *** injuries seem to have a multifactorial origin both in short-and long-distance runners.

关键词： Musculoskeletal health Protective factors running-related injury

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大别山双河和碧溪岭超高压变质岩流体包裹体研究

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岩石学报 2000年第1期16卷 119-126页

作者：傅斌肖益林 J L r Touret A M van den Kerkhof JHoefs 郑永飞中国科学技术大学地球与空间科学系 Facu lteit der Aard weten schappen Institute for Geology and Dynamics of Lithosphere Geochem ical Institute

对大别山双河和碧溪岭含柯石英榴辉岩和硬玉石英岩进行了详细的流体包裹体研究。根据流体包裹体的成分和盐度的不同 ,可以划分出至少五种类型不同的气液包裹体 :( 1) N2 包裹体 ;( 2 )高盐度流体包裹体 ;( 3) CO2 包裹体 ;( 4) CO2 -H2 ... 详细信息

对大别山双河和碧溪岭含柯石英榴辉岩和硬玉石英岩进行了详细的流体包裹体研究。根据流体包裹体的成分和盐度的不同 ,可以划分出至少五种类型不同的气液包裹体 :( 1) N2 包裹体 ;( 2 )高盐度流体包裹体 ;( 3) CO2 包裹体 ;( 4) CO2 -H2 O包裹体 ;( 5 )低盐度流体包裹体。N2 包裹体仅见于含柯石英榴辉岩 ,而高盐度流体包裹体则几乎存在于所有的榴辉岩和硬玉石英岩中。 CO2 包裹体沿榴辉岩中微剪切带分布 ,或存在于强变形的硬玉石英岩中 ,而低盐度流体包裹体分布较为局限。N2 和高盐度流体被认为是超高压变质作用平衡的产物 ,来源于变质前的古孔隙流体。而且榴辉岩中含有一系列盐度不同的流体显微域 ,其大小与矿物颗粒相当。在板块折返过程中 ,包裹体中流体可能发生迁移 ,但是不会超出寄主晶体的范围。CO2流体明显是外来的 ,可能来自共生大理岩或含碳酸盐的变质沉积岩。这与菱镁矿和柯石英等共生组合所指示的进变质过程中大理岩不存在脱碳反应的结论相一致。而低盐度流体则可能系顶峰变质矿物分解而成。

关键词：榴辉岩硬玉石英岩流体包裹体大别山变质岩

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