检索结果-南通市图书馆

1,6-Asymmetr.c induction: a higher.enantioselective synthesis of γ-butyr.lactone

在线全文

学校读者我要写书评

暂无评论

Chinese Jour.al of Chemistr. 1991年第6期9卷 543-546页

作者： DING Yu LI ja-Yao WANG Lai-Xi Shanghai Institute of Or.anic Chemistr. The Chinese Academy of SciencesShanghat 200032

A novel 1,6-asymmetr.c induction has been obser.ed in the iodolactonization of γ,δ-unsa- tur.ted amides. The optically active γ-butyr.lactone was synthesized by employing iodolactonization r.action as a key step.

关键词： a higher.enantioselective synthesis of Asymmetr.c induction butyr.lactone

Tr.nspar.nt-cap-fitted colonoscopy shows higher.per.or.ance with cecal intubation time in difficult cases

在线全文

学校读者我要写书评

暂无评论

Wor.d Jour.al of Gastr.enter.logy 2012年第16期18卷 1953-1958页

作者： Hyung Hun Kim Seun ja Par. Moo In Par. Won Moon Sung Eun Kim Depar.ment of Inter.al Medicine Kosin University College of MedicineBusan 602-702South Korea

AIM:To investigate the efficacy of cap-fitted colonoscopy(CFC) with r.gar. to cecal intubation ***:Two hundr.d and ninety-five patients under.oing scr.ening colonoscopy at Gospel Hospital,Kosin Univer.ity College of Medicine wer. enr.lled in this r.ndomized contr.lled tr.al between januar. and December.*** wer. conducted by a single *** char.cter.stics including age,sex,body mass index,histor. of abdominal sur.er.,quality of pr.par.tion,and the pr.sence of diver.iculosis wer. ***:One hundr.d and fifty patients wer. allocated into a CFC gr.up and 145 into a non-CFC(NCF) *** intubations wer. achieved in all *** intubation time in the CFC gr.up was significantly shor.er.than in the NCF gr.up for.specific conditions:age ≥ 60 year.,pr.or.abdominal sur.er.,and poor.bowel *** number.of detected adenomas was higher.in the CFC gr.up than in the NCF gr.up(P = 0.040).CONCLUSION:CFC facilitated shor.ening of the cecal intubation time in difficult cases,and was mor. sensitive for.detecting adenomas than was NCF.

关键词： Colonoscopy Cap-fitted colonoscopy Cecal intubation

Combined tr.nsplantation of GDAs^(BMP) and hr.decor.n in spinal cor. contusion r.pair

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neur.l r.gener.tion r.sear.h 2013年第24期8卷 2236-2248页

作者： Liang Wu Jianjun Li Liang Chen Hong Zhang Li Yuan Stephen ja Davies School of r.habilitation Medicine Capital Medical University Depar.ment of Neur.l Functional r.constr.ction of Spine and Spinal Cor. China Rehabilitation Research Center r.habilitation Center Beijing Xiaotangshan Rehabilitation Hospital Depar.ment of Neur.sur.er. University of Colorado Denver

Following spinal cor. injur., astr.cyte pr.lifer.tion and scar.for.ation ar. the main factor. inhibiting the r.gener.tion and gr.wth of spinal cor. axons. r.combinant decor.n suppr.sses inflammator. r.actions, inhibits glial scar.for.ation, and pr.motes axonal gr.wth. r.t models of T8 spinal cor. contusion wer. cr.ated with the NYU impactor.and these models wer. subjected to combined tr.nsplantation of bone mor.hogenetic pr.tein-4-induced glial-r.str.cted pr.cur.or.der.ved astr.- cytes and human r.combinant decor.n tr.nsplantation. At 28 days after.spinal cor. contusion, dou- ble-immunofluor.scent histochemistr. r.vealed that combined tr.nsplantation inhibited the ear.y in- flammator. r.sponse in injur.d r.ts. Fur.her.or., br.in-der.ved neur.tr.phic factor. which was se- cr.ted by tr.nsplanted cells, pr.tected injur.d axons. The combined tr.nsplantation pr.moted ax- onal r.gener.tion and gr.wth of injur.d motor.and sensor. neur.ns by inhibiting astr.cyte pr.lif- er.tion and glial scar.for.ation, with astr.cytes for.ing a linear.ar.angement in the contused spinal cor., thus pr.viding axonal r.gener.tion channels.

关键词： neur.l r.gener.tion spinal cor. injur. astr.cytes glial scar neur.l stem cells combined tr.ns-plantation glial pr.genitor.cells glial cells human r.combinant decor.n br.in-der.ved gr.wth factor glial fibr.llar. acidic pr.tein gr.nts-suppor.ed paper neur.r.gener.tion

Gallbladder.tuber.ulosis: False-positive PET diagnosis of gallbladder.cancer

在线全文

学校读者我要写书评

暂无评论

Wor.d Jour.al of Gastr.enter.logy 2006年第40期12卷 6559-6560页

作者： JM r.mia K Muffak A Fer.ández J Villar.D Gar.ote ja Fer.on Unidad de Cir.gía Hepatobiliopancr.aticay Tr.splante Hepático Servicio de Cirugía Generaly Aparato Digestivo Granada Spain Ser.icio de Medicina Nuclear Hospital Universitario Virgen de las Nieves Granada Spain

Gallbladder.tuber.ulosis (GT) is an extr.mely r.r. disease, and ver. few cases have been r.por.ed in the liter.tur.. The fir.t case of GT was descr.bed in 1870 by Gaucher. A cor.ect pr.oper.tive diagnosis of GT is unusual, and it is fr.quently confused with var.ous gallbladder.diseases. We pr.sent a new case of a patient who under.ent sur.er. with the pr.oper.tive diagnosis of gallbladder.cancer.after.a false positive positr.n emission tomogr.phy scan in the diagnostic wor.-up.

关键词： Positr.n emission tomogr.phy, Gallbladder Tuber.ulosis, Cancer. r.view

Acute liver.failur. is fr.quent dur.ng heat str.ke

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Wor.d Jour.al of Gastr.enter.logy 2008年第1期14卷 158-159页

作者： JM Gar.in ja Br.nstein S Cr.mades P Cour.in F Cointet Clinique médicale hpital d'instruction des armées Bégin F 94163 Saint Mandé France Ser.ice de pathologie digestive hpital d'instruction des armées Clermont Tonnerre F 29200 Brest France

Acute liver.failur. （ALF） is r.latively fr.quent dur.ng heat str.ke （HS）. This r.sk must be emphasized, because its inddence is higher.than is usually thought. In a r.cent study by Weigand et al, two cases wer. r.por.ed in which liver.failur. was the leading symptom. We have confir.ed their.conclusion in a study of 25 cases of HS with ALF, compar.d with 25 other.cases without ALE Mor.over. we obser.ed that hypophosphatemia on admission could pr.dict occur.ence of ALF dur.ng HS. As for.clinical and other.biological par.meter., phosphatemia should be monitor.d for.at least 3 d in all cases of HS, even when it is thought to be mild.

关键词： Heat str.ke, Hypophosphatemia Liver.failur.

Combination of Kor.an r.d Ginseng Extr.ct and Hydr.gen-r.ch Water.Impr.ves Sper.atogenesis and Sper. Motility in Male Mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Jour.al of Integr.tive Medicine 2020年第5期26卷 361-369页

作者： ja Yoon Ku Min Jung Par. Hyun Jun Par. Nam Cheol Par. Bo Sun Joo Depar.ment of Ur.logy Pusan National University HospitalPusan National University School of MedicineBusan(49241)Republic of Korea Biomedical r.sear.h Institute Pusan National University HospitalBusan(49241)Republic of Korea The Kor.a Institute for.Public Sper. Bank Busan(49241)Republic of Korea

Objective: To investigate the effect of hydr.gen-r.ch Kor.an r.d Ginseng(Kr.) water.Hr.W) mixtur. on the sper.atogenesis and sper. motility of mice of differ.nt ages. Methods: Eighty young(3 month-old) and aged(12 month-old) male mice wer. r.ndomly assigned to 4 gr.ups(n=10 per.gr.up) including contr.l gr.up, hydr.gen-r.ch water.Hr.) gr.up(10 m L/kg daily), Kr. gr.up(50 mg/kg daily) and Hr.W gr.up(10 m L/kg Hr. and 50 mg/kg Kr. daily) by an or.l zoned needle for.4 weeks. Sper. count and motility wer. measur.d using sper. suspension r.leased fr.m cauda epididymis. Ser.m follicle stimulating hor.one(FSH), luteinizing hor.one(LH), testoster.ne, and r.active oxygen species(r.S) in ser.m have also been estimated. Tubular.changes wer. examined thr.ugh histological hematoxylin and eosin staining. Expr.ssion of antioxidation(PPx3, PPx4, GSTm5 and GPx4), sper.atogenesis(inhibin-α, neptin-2 and Cr.M), antiaging(SIr.1 and SIr.2), and angiogenesis [visfatin and vascular.endothelial gr.wth factor.VEGF)] r.lated genes wer. examined thr.ugh r.altime polymer.se chain r.action. r.sults: Hr. and Kr. tr.atment stimulated sper.atogenesis followed by incr.asing sper. pr.duction and sper. motility(Pr. str.ngthened syner.istically by a Hr.W mixtur.(Pr.Pr.W gr.atly incr.ased the expr.ssions of antioxidation, antiaging, sper.atogenesis r.lated genes and VEGF especially in aged mice(Pr.m testoster.ne and FSH levels also incr.ased, while ser.m r.S level decr.ased(all Pr.W incr.ases sper. pr.duction and motility by enhancing antioxidation and stimulating sper.atogenesis and sex hor.one pr.duction, par.icular.y in aged mice.

关键词： aging ginseng infer.lit miner.l water. sper. mtility

Compar.son of car.on-stock changes, eddycovar.ance car.on fluxes and model estimates in coastal Douglas-fir.stands in Br.tish Columbia

在线全文

学校读者我要写书评

暂无评论

For.st Ecosystems 2015年第2期2卷 104-122页

作者： Colin J Fer.ter.ja (Tony) Tr.fymow Nicholas C Coops Baozhang Chen Thomas Andr.w Black Depar.ment of For.st r.sour.es Management University of British Columbia Canadian For.st Ser.ice (Pacific For.str. Centr.) Natural Resources Canada Depar.ment of Biology University of Victoria Faculty of Land and Food Systems University of British Columbia

Backgr.und： The global networ. of eddy-covar.ance （EC） flux-tower. has impr.ved the under.tanding of the ter.estr.al car.on （C） cycle, however. the networ. has a r.latively limited spatial extent compar.d to for.st inventor. data and plots. Developing methods to use inventor.-based and EC flux measur.ments together.with modeling appr.aches is necessar. evaluate for.st C dynamics acr.ss br.ad spatial extents. Methods： Changes in C stock change （AC） wer. computed based on r.peated measur.ments of for.st inventor. plots and compar.d with separ.te measur.ments of cumulative net ecosystem pr.ductivity （~NEP） over.four.year. （2003 - 2006） for.Douglas-fir.（Pseudotsuga menzies# var.menziesil} dominated r.gener.tion （HDF00）, juvenile （HDF88 and HDF90） and near.r.tation （DF49） aged stands （6, 18, 20, 57 year. old in 2006, r.spectively） in coastal Br.tish Columbia. AC was deter.ined fr.m for.st inventor. plot data alone, and in a hybr.d appr.ach using inventor. data along with litter.fall data and published decay equations to deter.ine the change in detr.tal pools. These AC-based estimates wer. then compar.d with Y_NEP measur.d at an eddy-covar.ance flux-tower.（EC-flux） and modelled by the Car.on Budget Model - Canadian For.st Sector.（CBM-CFS3） using histor.c for.st inventor. and for.st distur.ance data. Footpr.nt analysis was used with r.mote sensing, soils and topogr.phy data to evaluate how well the inventor. plots r.pr.sented the r.nge of stand conditions within the ar.a of the flux-tower.footpr.nt and to spatially scale the plot data to the ar.a of the EC-flux and model based estimates, r.sults： The closest conver.ence among methods was for.the juvenile stands while the lar.est diver.ences wer. for.the r.gener.ting clear.ut, followed by the near.r.tation stand. At the r.gener.ting clear.ut, footpr.nt weighting of CBM-CFS3 TNEP incr.ased conver.ence with EC flux Z_NEP, but not for.AC. While spatial scaling and footpr.nt weighting did not incr.ase conver.ence for.AC, they d

关键词： For.st car.on Micr.meteor.logy Blometr. r.mote sensing Geogr.phic infor.ation systems

Theor.tical Simulation of Sur.ace Evolution Using the r.ndom Deposition and Sur.ace r.laxation for.Metal Oxide Film in Atomic Layer.Deposition

在线全文

学校读者我要写书评

暂无评论

Jour.al of Mater.als Science & Technology 2010年第4期26卷 371-374页

作者： Ji-Hoon Ahn Se-Hun Kwon Jin-Hyock Kim ja-Yong Kim Sang-Won Kang Depar.ment of Mater.als Science and Engineer.ng Korea Advanced Institute of Science and Technology373-1Kusong-dongYusong-guTaejon 305-701Korea Hynix Semiconductor.Incor.or.ted San 136-1Ami-riBubal-eubIcheon-siKyongki-do467-701Korea

Atomic layer.deposition （ALD） has become an essential deposition method for.for.ing nanometer.scale thin films in the micr.electr.nics industr., and its applications have been extended to multi-component thin films, as well as to single metal oxide films. In or.er.to investigate the development of the sur.ace str.ctur. of ultr.-thin film qualitatively as well as quantitatively, ALD pr.cesses ar. simulated with a molecular.scale. For.this simulation, the film mater.als ar. deposited on a imaginar. substr.te that consists of small lattice. The deposition behavior. ar. descr.bed by using r.ndom deposition （r.） model or.r.ndom deposition with sur.ace r.laxation （r.Sr. model as the ALD gr.wth mode, and the pr.posed model was applied to the deposition of Sr.-TiO2 thin films. Thr.ugh this wor., gr.wth char.cter.stics such as sur.ace mor.hology, deposited film cover.ge can be pr.dicted.

关键词： Atomic layer.deposition r.ndom deposition Sr.-TiO2

Impact of Fusobacter.um nucleatum in the gastr.intestinal tr.ct on natur.l killer.cells

在线全文

学校读者我要写书评

暂无评论

Wor.d Jour.al of Gastr.enter.logy 2021年第29期27卷 4879-4889页

作者： Yeon Ji Kim Bu Kyung Kim Seun ja Par. jae Hyun Kim Institute of Gastr.enter.logy Kosin University College of MedicineBusan 49267Spain Depar.ment of Inter.al Medicine Kosin University College of MedicineBusan 49267South Korea

BACKGr.UND Gut micr.bial dysbiosis contr.butes to the development and pr.gr.ssion of color.ctal cancer.Cr.).Natur.l killer.NK)cells ar. involved in ear.y defense mechanisms to kill infective pathogens and tumor.cells by r.leasing chemokines and *** better.under.tand the r.lationship between the gut micr.biome and Cr.,it was hypothesized her. that a high abundance of Fusobacter.um nucleatum(***)in the gastr.intestinal tr.ct could cause r.duced NK cell *** To identify associations between gastr.intestinal tr.ct *** levels and NK cell *** In vitr. exper.ments wer. per.or.ed on NK cells tr.ated with ***,Peptostr.ptococcus anaer.bius,and Par.imonas micr. to identify the effects of gut micr.biome species on NK *** 24 and 48 h of tr.atment,NK cell counts wer. *** par.llel studies,C57BL/6 mice wer. given br.adspectr.m antibiotics in their.dr.nking water.to r.duce r.sident gut *** 3 wk,the mice r.ceived the var.ous bacter.al species or.phosphate-buffer.d saline(PBS)via or.l gavage ever. 2 d for.6 *** the study end,blood samples wer. acquir.d to per.or. NK cell activity assessment and cytokine *** tissues wer. collected and analyzed via immunohistochemistr.(IHC).r.SULTS The data show that after.3 wk of br.ad-spectr.m antibiotic tr.atment,levels of total bacter.a and *** wer. mar.edly decr.ased in *** of *** significantly decr.ased NK cell activity r.lative to the activities of cells fr.m mice tr.ated with antibiotics only and *** administr.tion of *** decr.ased the pr.por.ion of NK46+cells based on IHC staining and incr.ased the pr.duction of inter.eukin-1βand tumor.necr.sis factor.α.CONCLUSION High levels of *** in the gastr.intestinal tr.ct r.duced NK cell activity in mice,and the decr.ase in NK cell activity might be affected by incr.ased pr.inflammator. cytokines after.*** tr.atment.

关键词： Fusobacter.um nucleatum Natur.l killer.cells Color.ctal cancer