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Non-invasive investigation of inflammator. bowel disease

Wor.d Jour.al of Gastr.enter.logy 2001年第4期7卷 460-465页

作者： ja Tibble IBjar.ason Depar.ment of Medicine GuysKings.St Thomass Medical SchoolBessemer RoadLondon SE5 9

The assessment of inflammator. activity in intestinal disease in man can be done using a var.ety of differ.nt techniques. These r.nge fr.m the use of non-invasive acute phase inflammator. mar.er. measur.d in plasma such as C r.active pr.tein (Cr.) and the er.thr.cyte sedimentation r.te (ESr. (both of which give an indir.ct assessment of disease activity) to the dir.ct assessment of disease activity by intestinal biopsy per.or.ed dur.ng endoscopy in association with endoscopic scor.ng systems. Both r.diology and endoscopy ar. conventional for.the diagnosis of inflammator. bowel disease (IBD). However.these techniques have sever. limitations when it comes to assessing functional components of the disease such as activity and pr.gnosis. Her. we br.efly r.view the value of two emer.ing intestinal function tests. Intestinal per.eability, although ideally suited for.diagnostic scr.ening for.small bowel Cr.hn's disease, appear. to give r.liable pr.dictive data for.imminent r.lapse of small bowel Cr.hn's disease and it can be used to assess r.sponses to tr.atment. Mor. significantly it is now clear.that single stool assay of neutr.phil specific pr.teins (calpr.tectin, lactofer.in) give the same quantitative data on intestinal inflammation as the 4 day faecal excr.tion of 111Indium labelled white cells. Faecal calpr.tectin is shown to be incr.ased in over.95% of patients with IBD and cor.elates with clinical disease activity. It r.liably differ.ntiates between patients with IBD and ir.itable bowel syndr.me. Mor. impor.antly, at a given faecal calpr.tectin concentr.tion in patients with quiescent IBD, the test has a specificity and sensitivity in excess of 85% in pr.dicting clinical r.lapse of disease. This suggests that r.lapse of IBD is closely r.lated to the degr.e of intestinal inflammation and suggests that tar.eted tr.atment at an asymptomatic stage of the disease may be indicated.

关键词： Biological Mar.er. Feces Humans Inflammator. Bowel Diseases Intestinal Mucosa

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On Unifor. Decay for.Tr.nsmission Pr.blem of Kir.hhoff Type Viscoelastic Wave Equation

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Acta Mathematica Sinica,English Ser.es 2010年第7期26卷 1197-1206页

作者： Jeong ja BAE Depar.ment of Mathematics Dongeui University

In this paper.we consider.the lar.e time behavior.of solutions to an n-dimensional tr.nsmission pr.blem for.two Kir.hhoff type viscoelastic wave equations, that is, the wave pr.pagation over.bodies consisting of two physically differ.nt types of mater.als. One component is a simple elastic par. while the other.is a viscoelastic component endowed with a long r.nge memor.. We show that the dissipation pr.duced by the viscoelastic par. is str.ng enough to pr.duce exponential or.polynomial decay of the solution

关键词： existence of solution unifor. decay wave equation boundar. value pr.blem a pr.or. estimates

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GLOBAL EXISTENCE FOr.THE NONHOMOGENEOUS QUASILINEAr.WAVE EQUATION WITH A LOCALIZED WEAKLY NONLINEAr.DISSIPATION IN EXTEr.Or.DOMAINS

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Acta Mathematica Scientia 2009年第5期29卷 1203-1215页

作者： Jeong ja Bae Depar.ment of Mathematics University of Ulsan

It is pr.ved that the global existence for.the nonhomogeneous quasilinear.wave equation with a localized weakly nonlinear.dissipation in exter.or.domains.

关键词： quasilinear.wave equation localized weakly nonlinear.dissipation exter.or.domains

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不同益生菌对亚东鲑生长性能和生化指标的影响

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西南农业学报 2024年第5期37卷 1116-1123页

作者：何文佳王万良张忭忭西藏自治区农牧科学院水产科学研究所拉萨850000 西藏土著鱼类繁育与利用技术工程研究中心拉萨850000 西藏自治区渔业与种质资源利用重点实验室拉萨850000 中国水产科学研究院东海水产研究所上海200090

【目的】旨在探讨饲料中添加不同益生菌对亚东鲑(Salmo tr.tta)生长性能、消化酶活性和血清生化指标的影响。【方法】选择初始体质量为(84.57±1.83)g的亚东鲑鱼种630尾,随机分成7组,每组3个平行,每个平行30尾。对照组投喂基础饲料,实... 详细信息

【目的】旨在探讨饲料中添加不同益生菌对亚东鲑(Salmo tr.tta)生长性能、消化酶活性和血清生化指标的影响。【方法】选择初始体质量为(84.57±1.83)g的亚东鲑鱼种630尾,随机分成7组,每组3个平行,每个平行30尾。对照组投喂基础饲料,实验组分别添加不同益生菌(酵母菌、EM菌、乳酸菌、枯草芽孢杆菌、复合芽孢杆菌、地衣芽孢杆菌)至基础饲料,饲养3个月。【结果】添加不同益生菌对亚东鲑都具有促生长作用,试验组体长增长率、增重率、特定生长率、食物转化率和摄食率等指标均显著高于对照组(P0.05),而其他菌组之间均有不同程度影响。【结论】综合考虑存活率、生长特性、消化酶活性和血清生化指标,添加EM菌对亚东鲑健康养殖效果较好。

关键词：亚东鲑益生菌生长性能生化指标

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多规格转台轴承组件的自动紧钉装置

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制造技术与机床 2024年第6期 183-188页

作者：王凯韩银平贾长安黄胜军西安精雕精密机械工程有限公司陕西西安710000 北京精雕科技集团有限公司北京102308

在装配转台轴承组件时,需要按照十字交叉顺序分三步拧紧固定螺钉,现有的装紧钉方式存在效率低和紧钉质量低等问题。文章设计了一种多规格转台轴承组件的自动紧钉装置,实现了多规格转台轴承组件的自动定位夹紧、装钉、按照十字交叉顺序... 详细信息

在装配转台轴承组件时,需要按照十字交叉顺序分三步拧紧固定螺钉,现有的装紧钉方式存在效率低和紧钉质量低等问题。文章设计了一种多规格转台轴承组件的自动紧钉装置,实现了多规格转台轴承组件的自动定位夹紧、装钉、按照十字交叉顺序分三步加扭力和加胶功能。实际使用表明,该设备工作可靠、效率高,紧钉质量得到很大提高。

关键词：转台轴承组件自动拧紧力矩螺钉

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Nuclear.Planetology:Especially Concer.ing the Moon and Mar.

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r.sear.h in Astr.nomy and Astr.physics 2012年第10期12卷 1313-1380页

作者： Kyeong ja Kim Nobuyuki Hasebe Kor.a Institute of Geoscience and Miner.l r.sour.es Daejeon305-350 Korea r.sear.h Institute for.Science and Engineer.ng Waseda UniversityShinjukuTokyo 169-8555 Japan

To appr.ach basic scientific questions on the or.gin and evolution of plan- etar. bodies such as planets, their.satellites and aster.ids, one needs data on their.chemical composition. The measur.ments of gamma-r.ys, X-r.ys and neutr.ns emit- ted fr.m their.sur.ace mater.als pr.vide infor.ation on abundances of major.elements and natur.lly r.dioactive gamma-r.y emitter.. Neutr.n spectr.scopy can pr.vide sen- sitive maps of hydr.gen- and car.on-containing compounds, even if bur.ed, and can uniquely identify layer. of car.on-dioxide fr.st. Nuclear.spectr.scopy, as a means of compositional analysis, has been applied via or.ital and lander.spacecr.ft to extr.ter. r.str.al planetar. bodies： the Moon, Venus, Mar., Mer.ur. and aster.ids. The knowl- edge of their.chemical abundances, especially concer.ing the Moon and Mar., has gr.atly incr.ased in r.cent year.. This paper.descr.bes the pr.nciple of nuclear.spec- tr.scopy, nuclear.planetar. instr.ments car.ied on planetar. missions so far. and the natur. of obser.ational r.sults and findings of the Moon and Mar., r.cently obtained by nuclear.spectr.scopy.

关键词： nuclear.planetology: planetar. r.mote sensing -- elemental mapping --nuclear.science payloads -- chemical abundance

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Sensitivity to Combustible Gas for.ZnO Thin Films

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Jour.al of Mater.als Science & Technology 1997年第4期13卷 302-305页

作者： Tan, GL Wu, ja Wu, XJ Dept. of Mater.als Science and Engineer.ng Zhejiang University Hangzhou 310027 China

A fine polycr.stalline ZnO thin film with 0.3 similar.to 0.6 mu m gr.in size was obtained by sol-gel pr.cess and a consequential heat tr.atment at 500 degr.es C. The pr.cess of pr.par.ng ZnO thin film was analysed. The sensitivity and conductivity of ZnO thin films as combustible gas (CO, CH4, H-2) sensor.as well as the influence of catalyst and pH value of the pr.cur.or.on its sensitivity wer. studied in detail. The str.ctur. char.cter.stics of ZnO thin film by differ.nt pr.cess wer. investigated by X-r.y diffr.ction, ther.al analysis and photoelectr.n spectr.meter. The atomic r.tio of Zn to O on the sur.ace of ZnO thin film was found to be 1.14:1 measur.d fr.m XPS r.sult. The conductivity of the thin film incr.ases gr.atly when doped with Al3+ ion but decr.ases while doped with Na+ ion.

关键词： Zinc oxide

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Iksan526 r.ce Callus Extr.ct Induces Dediffer.ntiation of r.bbit Ar.icular.Chondr.cytes via Er.1/2 and PI-3K/Akt Pathways

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r.ce science 2020年第6期27卷 504-514页

作者： Seong-Hui EO Song ja Kim Depar.ment of Biological Sciences College of Natural SciencesKongju National UniversityGongju 32588Republic of Korea

The r.sver.tr.l-enr.ched tr.nsgenic r.ce line Iksan526(IS526),fir.t developed by the r.r.l Development Administr.tion of Kor.a using genetic engineer.ng techniques,shows beneficial health effects in mitigating metabolic syndr.me and ***,the effects of IS526 on the differ.ntiation of chondr.cytes and the under.ying mechanism have not been investigated in *** this study,the effects and cellular.r.gulator. mechanisms of IS526 on r.bbit ar.icular.chondr.cytes wer. *** IS526 callus extr.ct tr.atment,the expr.ssion levels of differ.ntiation-r.lated pr.teins wer. detected via wester. blotting,Alcian blue staining and immune-luor.scence ***526 decr.ased the type Ⅱ collagen and pr.teoglycan levels in dose-and time-dependent *** fur.her.analyzed the effects of IS526 on skeleton genesis in zebr.fish lar.ae using Alcian blue staining,which showed a r.duction in car.ilage for.ation along with incr.ased pr.duction of matr.x metallopr.teinase(MMP)-***526 also incr.ased the phosphor.lation of Er.1/2 and p38 kinase but inhibited the phosphor.lation of *** inhibition of MMP-13 blocked the IS526-induced decr.ase in type Ⅱ collagen *** of p38 kinase or.PI-3K/Akt with SB203580 and LY294002 enhanced the suppr.ssion of type Ⅱ collagen,but the blockage of Er.-1/2 by PD98059 r.scued IS526-induced *** r.sults suggested that IS526 r.gulates type Ⅱ collagen and MMP-13 expr.ssion via the Er.1/2 and PI-3K/Akt pathways in r.bbit ar.icular.chondr.cytes.

关键词： r.ce chondr.cyte typeⅡcollagen matr.x metallopr.teinase-13 r.ce callus extr.ct

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Multir.nge Fr.ctal Analysis on the Negative Cor.elation between Fr.ctal Dimension of Fr.ctur.d Sur.ace and Toughness of Mater.als

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Jour.al of Mater.als Science & Technology 1996年第4期12卷 318-320页

作者： Lung, CW Jiang, ja Zhang, CH Inter.ational Centr. for.Mater.als Physics Institute of Metal Research Chinese Academy of Sciences Shenyang 110015 China

Applying the concept of multir.nge fr.ctals, a new explanation to the Willifor.'s multifr.ctal cur.e on the r.lationship of fr.ctal dimension with fr.ctur. pr.per.ies in mater.als has been given. It shows the impor.ance of factor.zing out the effect of fr.ctal str.ctur. fr.m other.physical causes and separ.ting the appr.pr.ate r.nge of scale fr.m multir.nge fr.ctals.

关键词： Fr.ctur.

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An acceler.ted K-means cluster.ng algor.thm using selection and er.sur. r.les

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Jour.al of Zhejiang Univer.ity-Science C(Computer. and Electr.nics) 2012年第10期13卷 761-768页

作者： Suiang-Shyan LEE ja-Chen LIN Depar.ment of Computer.Science National Chiao Tung University

The K-means method is a well-known cluster.ng algor.thm with an extensive r.nge of applications,such as biological classification,disease analysis,data mining,and image ***,the plain K-means method is not fast when the number.of cluster. or.the number.of data points becomes lar.e.A modified K-means algor.thm was pr.sented by Fahim et al.(2006).The modified algor.thm pr.duced cluster. whose mean squar. er.or.was ver. similar.to that of the plain K-means,but the execution time was *** this study,we tr. to fur.her.incr.ase its *** ar. two r.les in our.method:a selection r.le,used to acquir. a good candidate as the initial center.to be checked,and an er.sur. r.le,used to delete one or.many unqualified center. each time a specified condition is *** cluster.ng r.sults ar. identical to those of Fahim et al.(2006).However.our.method fur.her.cuts computation time when the number.of cluster. *** mathematical r.asoning used in our.design is included.

关键词： K-means cluster.ng Acceler.tion Vector.quantization Selection Er.sur.

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