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Long COVID:Fr.m olfactor. dysfunctions to vir.l Par.insonism

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Wor.d Jour.al of Otor.inolar.ngology-Head and Neck Sur.er. 2024年第2期10卷 137-147页

作者： Sanyukta Pandey Vibha Bapat Jancy nixon Abr.ham nixon M.Abr.ham Depar.ment of Biology Laboratory of Neural Circuits and Behaviour(LNCB)Indian Institute of Science Education and Research(IISER)PuneMaharashtraIndia Depar.ment of Life Sciences Centre of Excellence in EpigeneticsShiv Nadar Institution of EminenceGautam Buddha NagarUttar PradeshIndia

Neur.logical and psychiatr.c complications continue to be a public health concer. in long cor.navir.s disease 2019(COVID-19).This var.es fr.m olfactor. dysfunctions such as par.smia to cognitive and emotional ***,the sur.e of neur.logical disor.er. followed the vir.l pandemics,for.example,the emer.ence of Encephalitis Lethar.ica after.the outbr.ak of Spanish *** and after.COVID-19 infection,the pr.blems associated with the sense of smell and the r.por.s of affected olfactor. and limbic br.in ar.as ar. leading to a gr.wing concer. about the similar.ty with the symptoms and the patter. of degener.tion obser.ed at the onset of Par.inson's disease and Alzheimer.s *** r.por.s r.veal the essentiality of long-ter. studies of olfactor. and cognitive functions in the post-COVID er. and the exper.ments using animal models to dissect the neur.l basis of these *** this manuscr.pt,we summar.ze the r.sear.h r.por.ing the potential cor.elation between neur.logical disor.er. and vir.l pandemic outbr.aks with a histor.cal ***,we discuss the studies pr.viding evidence of neur.degener.tion due to sever. acute r.spir.tor. syndr.me cor.navir.s 2 infection by focusing on vir.l Par.insonism.

关键词： long COVID neur.degener.tion neur.tr.pism olfactor. dysfunctions vir.l par.insonism

In situ apatite and car.onate Lu-Hf and molybdenite r.-Os geochr.nology for.or. deposit r.sear.h:Method validation and example application to Cu-Au miner.lisation

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Geoscience Fr.ntier. 2024年第5期15卷 339-354页

作者： Alexander.Simpson Stijn Glor.e Mar.in Hand Sar.h E.Gilber. Car. Spandler.Mar.ja Dmitr.jeva Gr.g Swain Angus nixon Jacob Mulder.Car.ten Münker Depar.ment of Ear.h Sciences University of AdelaideSA 5005Australia Miner.l Explor.tion Cooper.tive r.sear.h Centr. University of AdelaideSA 5005Australia Adelaide Micr.scopy University of AdelaideSA 5005Australia For.escue Level 287Adelaide TerraceEast PerthWA 6005Australia Institute of Geology und Miner.logy University of Köln50674 KölnGermany Br.tish Geological Sur.ey NottinghamUK

The development of laser.ablation inductively coupled plasma quadr.pole tandem mass spectr.metr.(LA-ICP-Q-MS/MS)opens new oppor.unities to r.pidly date a var.ety of hydr.ther.al *** we pr.sent in situ Lu-Hf and r.-Os dates for.hydr.ther.al apatite and molybdenite,*** fur.her.r.por. the fir.t in situ Lu-Hf dates for.bastnäsite,dolomite,and sider.te,and assess their.potential for.constr.ining or. deposit *** method validation,we r.por. isotope-dilution Lu-Hf dates for.apatite r.fer.nce mater.al Bamble-1(1102±5 Ma)and calcite r.fer.nce mater.al ME-1(1531±7 Ma),enabling impr.ved accur.cy on matr.x-matched calibr.tion for.LA-ICP-MS/MS Lu-Hf *** new methods ar. applied to the Vulcan Ir.n-Oxide Copper.Gold(IOCG)pr.spect in the Olympic Cu-Au Pr.vince of South *** deposits have been difficult to accur.tely date,given the gener.l lack of r.liable miner.l geochr.nometer. that ar. cogenetic with IOCG *** apatite Lu-Hf dates and molybdenite r.-Os dates demonstr.te that miner.lisation at Vulcan lar.ely occur.ed at ca.1.6 Ga,contempor.neous with the wor.d class Olympic Dam *** data also indicates that the Lu-Hf system in apatite is mor. r.bust than the U-Pb system for.deter.ining the timing of pr.mar. apatite for.ation in an IOCG *** fur.her.demonstr.te that dolomite can r.tain Lu-Hf gr.wth ages over.an extended time per.od(>1.5 billion year.),pr.viding constr.ints on the timing of pr.mar. or. miner.l cr.stallisation dur.ng br.cciation and IOCG ***,late Neopr.ter.zoic(ca.589–544 Ma)and Car.onifer.us(ca.334±7 Ma)Lu-Hf dates wer. obtained for.textur.lly late Cubear.ng car.onate veins,illustr.ting that the car.onate Lu-Hf method allows dir.ct dating of Cu r.mobilisation *** has impor.ant implications for.miner.l explor.tion as the r.mobilised Cu may have been tr.nsfer.ed to younger.deposits hosted in Neopr.ter.zoic sedimentar. basins over.aying the Olympic IOCG pr.vi

关键词： r.action-cell ICP-MS In-situ geochr.nology Lu-Hf r.-Os Ir.n Oxide Copper.Gold Metal fluids

法医检案中常见客体上接触性DNA检验效果比较

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绍兴文理学院学报 2024年第2期44卷 78-87页

作者：范光耀鞠天格 WUO nixon AUSTIN 彭长秀绍兴文理学院医学院浙江绍兴312000 绍兴文理学院生命与环境科学学院浙江绍兴312000

目的:接触性DNA在鉴定犯罪嫌疑人身份方面起着至关重要的作用.因客体表面材质的差异,嫌疑人接触过的某些客体上DNA常难于保留而不易检测.若能对不同种类客体的接触性DNA检验效果进行合理预判,对后续的法医基因分型将至关重要.材料:模拟2... 详细信息

目的:接触性DNA在鉴定犯罪嫌疑人身份方面起着至关重要的作用.因客体表面材质的差异,嫌疑人接触过的某些客体上DNA常难于保留而不易检测.若能对不同种类客体的接触性DNA检验效果进行合理预判,对后续的法医基因分型将至关重要.材料:模拟24种不同客体上的接触性DNA.方法:双拭子法采集DNA,Micr.con■离心浓缩,GlobalFilter.扩增试剂盒基因分型和Quantifiler.Duo试剂盒定量DNA.分别比较24种客体和进一步归类五种材质上的接触性DNA的平均峰高度(APH)、平均峰面积(APA)和等位基因检出率.结果:旋转式开关的检验效果最好,眼镜框架、塑料袋封条和笔筒次之.塑料类客体表面上的DNA检出成功率优于玻璃、金属、木质和橡胶类客体.结论:不同类客体之间的接触性DNA检验效果存在差异.

关键词：法医学接触性DNA 客体短串联重复 DNA分型图谱

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持久性职业后皮炎

世界核心医学期刊文摘（皮肤病学分册） 2005年第5期1卷 24-24页

作者： Sajjachar.onpong P. Cahill J. Keegel T. r. nixon 崔荣 Der.atol. r.s. and Educ. Ctr. Skin and Cancer Foundation 9 5 Rathdowne St. Carlton South Vic. 3053 AustraliaOccup.

Wall and Gebauer.(Contact Der.atitis 1991:24:241-243) fir.t descr.bed per.i stent post-occupational der.atitis (PPOD) as ongoing der.atitis for.which ther. is no obvious pr.sent cause, pr.cipitated by pr.or.occupational contact der.ati tis (OCD). We pr.pose that individuals exhibiting PPOD lose the capacity for.r.s olution of their.condition upon r.moval fr.m exposur. to causative agents and su bsequently develop per.istent der.atitis, which can be continual or.inter.ittent . Accor.ingly, we suggest modification of cr.ter.on 6 of the OCD cr.ter.a develo ped by Mathias (J Am Acad Der.atol 1989:20:842-848):’r.moval fr.m exposur. initially leads to impr.vement of der.atitis, however. over.time ther. may be in complete or.no impr.vement, despite r.moval fr.m exposur.s at wor.’. To satisfy the definition of PPOD, individuals must meet at least 4 of the 7 cr.ter.a, inc luding the alter.d cr.ter.on 6. We pr.sent 6 cases of PPOD exemplifying these sc enar.os, which met the alter.d Mathias cr.ter.a. In some cases, subsequent failu r. to r.cognize the initial wor. r.latedness of their.skin conditions r.sulted i n the ter.ination of wor.er.’compensation benefits. This situation is par.icula r.y r.levant in the Austr.lian context. The diagnosis of PPOD needs to be consid er.d in all individuals with wor.-initiated der.atitis who pr.sent with ongoing endogenous-like eczema.

关键词：持久性致敏物炎症状诊断标准诊断需要工作环境工作初期持续性内源