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Early postoperative complications after transverse colostomy closure,a retrospective study

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 807-815页

作者： Fei Liu Xiao-Juan luo Zi-Wei Li Xiao-Yu Liu Xu-Rui Liu quan Lv Xin-Peng Shu Wei Zhang Dong Peng Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Endoscopy Center The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400012China

BACKGROUND Ostomy is a common surgery usually performed to protect patients from clinical symptoms caused by distal anastomotic leakage after colorectal cancer(CRC)surgery and perforation or to relieve intestinal *** To analyze the complications after transverse colostomy *** Patients who underwent transverse colostomy closure from Jan 2015 to Jan 2022 were retrospectively enrolled in a single clinical *** differences between the complication group and the no complication group were *** regression analyses were conducted to find independent factors for overall complications or incision *** A total of 102 patients who underwent transverse colostomy closure were enrolled in the current ***(68.6%)patients underwent transverse colostomy because of CRC related *** complications occurred in 30(29.4%)patients and the most frequent complication occurring after transverse colostomy closure was incision infection(46.7%).The complication group had longer hospital stays(P<0.01).However,no potential risk factors were identified for overall complications and incision *** The most frequent complication occurring after transverse colostomy closure surgery in our center was incision *** operation time,interval from transverse colostomy to reversal,and method of anastomosis might have no impact on the postoperative *** should pay more attention to aseptic techniques.

关键词： Transverse colostomy closure Surgery Complications A single clinical centre Risk factors

General anesthetic agents induce neurotoxicity through oligodendrocytes in the developing brain

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Zoological Research 2024年第3期45卷 691-703页

作者： Wen-Xin Hang Yan-Chang Yang Yu-Han Hu Fu-quan Fang Lang Wang Xing-Hua Qian Patrick M.McQuillan Hui Xiong jian-Hang Leng Zhi-Yong Hu Department of Anesthesiology First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310003China Department of Cell Biology Yale UniversityNew HavenCT 06520USA Department of Neurology of the First Affiliated Hospital Interdisciplinary Institute of Neuroscience and TechnologySchool of Brain Science and Brain MedicineZhejiang University School of MedicineHangzhouZhejiang 310027China Department of Anesthesiology Jiaxing Maternity and Childcare Health HospitalJiaxingZhejiang 314009China Department of Anesthesiology Penn State Hershey Medical CentrePenn State College of MedicineHersheyPA 17033USA Department of Central Laboratory Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang 310006China

General anesthetic agents can impact brain function through interactions with neurons and their effects on glial *** perform essential roles in the central nervous system,including myelin sheath formation,axonal metabolism,and neuroplasticity *** are particularly vulnerable to the effects of general anesthetic agents resulting in impaired proliferation,differentiation,and *** are increasingly interested in the effects of general anesthetic agents on *** agents not only act on the surface receptors of oligodendrocytes to elicit neuroinflammation through modulation of signaling pathways,but also disrupt metabolic processes and alter the expression of genes involved in oligodendrocyte development and *** this review,we summarize the effects of general anesthetic agents on *** anticipate that future research will continue to explore these effects and develop strategies to decrease the incidence of adverse reactions associated with the use of general anesthetic agents.

关键词： Oligodendrocytes General anesthetic agents Neurotoxicity Central nervous system Perioperative neurocognitive disorders

Single crystal growth and transport properties of narrow-bandgap semiconductor RhP_(2)

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Chinese Physics B 2024年第8期33卷 545-549页

作者：吴德胜郑萍雒建林 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China Songshan Lake Materials Laboratory Dongguan 523808China quantum Science Center of Guangdong–Hong Kong–Macao Greater Bay Area(Guangdong) Shenzhen 518045China

We report the growth of high-quality single crystals of RhP_(2),and systematically study its structure and physical properties by transport,magnetism,and heat capacity ***-crystal x-ray diffraction reveals that RhP_(2) adopts a monoclinic structure with the cell parameters a=5.7347(10)A,b=5.7804(11)A,and c=5.8222(11)A,space group P2_(1)/c(No.14).The electrical resistivityρ(T)measurements indicate that RhP_(2) exhibits narrow-bandgap behavior with the activation energies of 223.1 meV and 27.4 meV for two distinct regions,*** temperaturedependent Hall effect measurements show electron domain transport behavior with a low charge carrier *** find that RhP_(2) has a high mobilityμ_(e)~210 cm^(2)·V^(-1)·s^(-1)with carrier concentrations n_(e)~3.3×10^(18)cm^(3) at 300 K with a narrow-bandgap *** high mobilityμ_(e) reaches the maximum of approximately 340 cm^(2)·V^(-1)·s^(-1)with carrier concentrations n_^(e)~2×10^(18)cm^(-3)at 100 *** magnetic phase transitions are observed from the susceptibilityχ(T)and specific heat C_(p)(T)measurements of RhP_(2).Our results not only provide effective potential as a material platform for studying exotic physical properties and electron band structures but also motivate further exploration of their potential photovoltaic and optoelectronic applications.

关键词： single crystal growth narrow band system electrical transport high mobilities

Pain perception enhancement in consecutive secondeye phacoemulsification cataract surgeries under topical anesthesia

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International Journal of Ophthalmology(English edition) 2024年第8期17卷 1510-1518页

作者： Jia-Wei luo Yan-Hua Chen jian-Feng Yu Yi-Xun Chen Min Ji Huai-Jin Guan Eye Institute Affiliated Hospital of Nantong UniversityMedical School of Nantong UniversityNantong 226001Jiangsu ProvinceChina Nantong Center for Disease Control and Prevention Nantong 226001Jiangsu ProvinceChina

Cataract is the main cause of visual impairment and blindness worldwide while the only effective cure for cataract is still *** phacoemulsification under topical anesthesia has been the routine procedure for cataract ***,patients often grumbled that they felt more painful during the second-eye surgery compared to the first-eye *** intraoperative pain experience has negative influence on satisfaction and willingness for second-eye cataract surgery of patients with bilateral *** ocular pain is a complicated process induced by the nociceptors activation in the peripheral nervous ***,neuropsychological,and pharmacological factors work together in the enhancement of intraoperative *** published literatures have focused on the pain enhancement during the secondeye phacoemulsification *** this review,we searched PubMed database for articles associated with pain perception differences between consecutive cataract surgeries published up to Feb.1,*** summarized the recent research progress in mechanisms and interventions for pain perception enhancement in consecutive secondeye phacoemulsification cataract *** review aimed to provide novel insights into strategies for improving patients’intraoperative experience in second-eye cataract surgeries.

关键词： ocular pain cataract surgery topical anesthesia intraoperative experience second-eye phacoemulsification

Establishment of a cholangiocarcinoma risk evaluation model based on mucin expression levels

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1344-1360页

作者： Chun-Yuan Yang Li-Mei Guo Yang Li Guang-Xi Wang Xiao-Wei Tang Qiu-Lu Zhang Ling-Fu Zhang jian-Yuan luo Department of Pathology Institute of Systems BiomedicineSchool of Basic Medical Sciences Peking UniversityPeking University Third HospitalPeking University Health Science CenterBeijing 100191China Department of General Surgery Peking University Third HospitalBeijing 100191China Department of Medical Genetics Department of Biochemistry and BiophysicsSchool of Basic Medical Sciences Peking UniversityPeking University Health Science CenterBeijing 100191China

BACKGROUND Cholangiocarcinoma(CCA)is a highly malignant cancer,characterized by frequent mucin ***1 has been identified as a critical oncogene in the progression of ***,the comprehensive understanding of how the mucin family influences CCA progression and prognosis is still *** To investigate the functions of mucins on the progression of CCA and to establish a risk evaluation formula for stratifying CCA *** Single-cell RNA sequencing data from 14 CCA samples were employed for elucidating the roles of mucins,complemented by bioinformatic ***-quent validations were conducted through spatial transcriptomics and *** construction of a risk evaluation model utilized the least absolute shrinkage and selection operator regression algorithm,which was further confirmed by independent cohorts and diverse data *** CCA tumor cells with elevated levels of MUC1 and MUC4 showed activated nucleotide metabolic pathways and increased ***5AC-high cells were found to promote CCA progression through WNT ***5B-high cells exhibited robust cellular oxidation activities,leading to resistance against antitumoral ***13-high cells were observed to secret chemokines,recruiting and transforming macrophages into the M2-polarized state,thereby suppressing antitumor ***16-high cells were found to promote tumor progression through interleukin-1/nuclear factor kappa-light-chain-enhancer of activated B cells signaling upon interaction with *** the expression levels of these mucins,a risk factor evaluation formula for CCA was developed and validated across multiple *** samples with higher risk factors exhibited stronger metastatic potential,chemotherapy resistance,and poorer *** Our study elucidates the functional mechanisms through which mucins contribute to CCA development,and provides tools for risk stratification in CCA.

关键词： Mucin Cholangiocarcinoma Single-cell RNA sequencing Spatial transcriptomics Prognosis

Plasma potential measurements using an emissive probe made of oxide cathode

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Chinese Physics B 2024年第4期33卷 571-577页

作者：李建泉马海杰陆文琪 Department of Electronic and Communication Engineering North China Electric Power UniversityBaoding 071003China Hebei Key Laboratory of Power Internet of Things Technology North China Electric Power UniversityBaoding 071003China Key Laboratory of Materials Modification by Laser Ion and Electron BeamsSchool of PhysicsDalian University of TechnologyDalian 116024China

A novel emissive probe consisting of an oxide cathode coating is developed to achieve a low operating temperature and long service *** properties of the novel emissive probe are investigated in detail,in comparison with a traditional tungsten emissive probe,including the operating temperature,the electron emission capability and the plasma potential *** of the operating temperature and electron emission capability show that the tungsten emissive probe usually works at a temperature of 1800 K-2200 K while the oxide cathode emissive probe can function at about 1200 K-1400 *** addition,plasma potential measurements using the oxide cathode emissive probe with different techniques have been accomplished in microwave electron cyclotron resonance plasmas with different discharge *** is found that a reliable plasma potential can be obtained using the improved inflection point method and the hot probe with zero emission limit method,while the floating point method is invalid for the oxide cathode emissive probe.

关键词： emissive probe oxide cathode plasma potential filament temperature

Observational appearance and extra photon rings of an asymmetric thin-shell wormhole with a Bardeen profile

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Chinese Physics C 2024年第6期48卷 211-221页

作者：何柯腱罗智郭森李国平 Department of Physics Chongqing UniversityChongqing 401331China Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China School of Physics and Astronomy China West Normal UniversityNanchong 637000China

In this work,the optical appearance of an asymmetric thin-shell wormhole with a Bardeen profile is *** initiate the process,we need to construct an asymmetric thin-shell wormhole utilizing the cut-and-paste technique proposed by Visser and subsequently ascertain its pertinent physical quantities such as the radius of the photon sphere and critical impact parameters for different values of magnetic charge ***,the effective potential and motion behavior of photons are also investigated within the framework of asymmetric thin-shell wormholes with a Bardeen *** can be found that the effective potential,ray trajectory,and azimuthal angle of the thin-shell wormhole exhibit a strong correlation with the mass ratio of black *** considering the accretion disk as the sole background light source,we observe additional photon rings and lensing bands in the optical appearance of the asymmetric thin-shell wormhole with a Bardeen profile compared to those exhibited by the Bardeen black *** can find that there is an increase in the size of the specific additional light bands with increasing magnetic charge g,which is different from the black hole *** exceptionally luminous rings can serve as a robust criterion for the identification and characterization of the thin-shell wormhole spacetime.

关键词： shadow asymmetric thin-shell wormhole Bardeen black hole

Integration of communications,sensing and computing

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Journal of Information and Intelligence 2024年第4期2卷 287-288页

作者： Zhi-quan luo Hongwei Liu Zhi Tian Nan Zhao The Chinese Academy of Engineering China The Chinese University of Hong Kong ShenzhenChina Xidian University China George Mason University USA

With the increasing demand for wireless services and advancements in science and technology,the integration of communications,sensing and computing(I-CSC)has emerged as a research hotspot in the field of information and communication technology.I-CSC is a new information processing paradigm that tightly integrates communications,sensing,and computing to create a cohesive system where these components are designed to work synergistically,enhancing the overall efficiency and reliability of information transmission and processing.

关键词： computing technology. services

Correlation between Combined Urinary Metal Exposure and Grip Strength under Three Statistical Models:A Cross-sectional Study in Rural Guangxi

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Biomedical and Environmental Sciences 2024年第1期37卷 3-18页

作者： LIANG Yu jian RONG Jia Hui WANG Xue Xiu CAI jian Sheng QIN Li Dong LIU Qiu Mei TANG Xu MO Xiao Ting WEI Yan Fei LIN Yin Xia HUANG Shen Xiang luo Ting Yu GOU Ruo Yu CAO Jie Jing HUANG Chu Wu LU Yu Fu QIN jian ZHANG Zhi Yong Department of Environmental and Occupational Health School of Public HealthGuangxi Medical UniversityNanning 530021GuangxiChina Key Laboratory of Tumor Immunology and Microenvironmental Regulation Guilin Medical UniversityGuilin 541199GuangxiChina Department of Environmental Health and Occupational Medicine School of Public HealthGuilin Medical UniversityGuilin 541199GuangxiChina Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases Guangxi Medical UniversityNanning 530021GuangxiChina Guangxi Key Laboratory of Environment and Health Research Guangxi Medical UniversityNanning 530021GuangxiChina Key Laboratory of Longevity and Aging-related Diseases of Chinese Ministry of Education Guangxi Medical UniversityNanning 530021GuangxiChina Guangxi Health Commission Key Laboratory of Entire Lifecycle Health and Care Guilin Medical UniversityGuilin 541199GuangxiChina

Objective This study aimed to investigate the potential relationship between urinary metals copper(Cu),arsenic(As),strontium(Sr),barium(Ba),iron(Fe),lead(Pb)and manganese(Mn)and grip *** We used linear regression models,quantile g-computation and Bayesian kernel machine regression(BKMR)to assess the relationship between metals and grip *** In the multimetal linear regression,Cu(β=−2.119),As(β=−1.318),Sr(β=−2.480),Ba(β=0.781),Fe(β=1.130)and Mn(β=−0.404)were significantly correlated with grip strength(Pquantile g-computation showed that the risk of occurrence of grip strength reduction was−1.007(95%confidence interval:−1.362,−0.652;P<0.001)when each quartile of the mixture of the seven metals was *** kernel function regression model analysis showed that mixtures of the seven metals had a negative overall effect on grip strength,with Cu,As and Sr being negatively associated with grip strength *** the total population,potential interactions were observed between As and Mn and between Cu and Mn(P_(interactions) of 0.003 and 0.018,respectively).Conclusion In summary,this study suggests that combined exposure to metal mixtures is negatively associated with grip ***,Sr and As were negatively correlated with grip strength levels,and there were potential interactions between As and Mn and between Cu and Mn.

关键词： Urinary metals Handgrip strength quantile g-computation Bayesian kernel machine regression