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Energy beam-based direct and assisted polishing techniques for diamond:A review

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International Journal of Extreme Manufacturing 2024年第1期6卷 93-124页

作者： Zhuo Li Feng Jiang Zhengyi Jiang Zige Tian Tian Qiu Tao Zhang qiuling Wen Xizhao Lu Jing Lu Hui huang Institute of Manufacturing Engineering Huaqiao UniversityXiamen 361021People’s Republic of China School of Mechanical MaterialsMechatronic and Biomedical EngineeringUniversity of WollongongWollongongNSW 2522Australia College of Mechanical Engineering and Automation Huaqiao UniversityXiamen 361021People’s Republic of China State Key Laboratory of High Performance Tools Huaqiao UniversityXiamen 361021People’s Republic of China

Diamond is a highly valuable material with diverse industrial applications,particularly in the fields of semiconductor,optics,and high-power electronics.However,its high hardness and chemical stability make it difficult to realize high-efficiency and ultra-low damage machining of diamond.To address these challenges,several polishing methods have been developed for both single crystal diamond(SCD)and polycrystalline diamond(PCD),including mechanical,chemical,laser,and ion beam processing methods.In this review,the characteristics and application scope of various polishing technologies for SCD and PCD are highlighted.Specifically,various energy beam-based direct and assisted polishing technologies,such as laser polishing,ion beam polishing,plasma-assisted polishing,and laser-assisted polishing,are summarized.The current research progress,material removal mechanism,and infuencing factors of each polishing technology are analyzed.Although some of these methods can achieve high material removal rates or reduce surface roughness,no single method can meet all the requirements.Finally,the future development prospects and application directions of different polishing technologies are presented.

关键词： single crystal diamond polycrystalline diamond energy beam polishing technology material removal mechanism influencing factors

Research progress of acupuncture analgesia based on autonomic nerve regulation pathway

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Acupuncture and Herbal Medicine 2023年第4期3卷 285-295页

作者： Lina Pang Xiaomei Chen Yanyan Lan qiuling huang Xiangmei Yu Lu Qi Zhifu Wang Department of Acupuncture Chongqing Hospital of Traditional Chinese MedicineChongqingChina School of Rehabilitation Medicine Fujian University of Traditional Chinese MedicineFuzhouChina School of Integrative Medicine Fujian University of Traditional Chinese MedicineFuzhouChina School of Life Sciences Westlake UniversityHangzhouChina Department of Acupuncture Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese MedicineFuzhouChina

The autonomic nervous system(ANS)includes the sympathetic,parasympathetic,and enteric nervous systems,and its senior regulatory center includes the brainstem,cingulate gyrus,and hypothalamus.Acupuncture can affect visceral,vascular,and glandular functions via the autonomic nervous regulatory pathway.In this paper,the relationship between pain and autonomic nervous function,the application of acupuncture guided by the autonomic nervous system,and the basis and clinical research on acupuncture analgesia are reviewed.

关键词： Acupuncture Autonomic nervous system Pain Progress

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激光复合加工硬脆性材料研究进展综述

机械工程学报 2024年第9期60卷 168-188页

作者：温秋玲杨野黄辉黄国钦胡中伟陈金鸿汪晖吴贤华侨大学制造工程研究院厦门361021 高性能工具全国重点实验室(华侨大学) 厦门361021 华侨大学机电及自动化学院厦门361021

玻璃、半导体、蓝宝石、陶瓷和硬质合金等硬脆性材料被广泛应用于建筑、生物医疗、航空航天、集成电路、新能源、光电显示、轨道交通、海洋等领域。但是其高硬度、大脆性、高耐磨性和耐腐蚀等特性也给它们的加工带来巨大挑战。目前,机... 详细信息

玻璃、半导体、蓝宝石、陶瓷和硬质合金等硬脆性材料被广泛应用于建筑、生物医疗、航空航天、集成电路、新能源、光电显示、轨道交通、海洋等领域。但是其高硬度、大脆性、高耐磨性和耐腐蚀等特性也给它们的加工带来巨大挑战。目前,机械加工、离子束加工、化学蚀刻、激光加工等方式是加工硬脆性材料的主要方法。但是这些加工方式依然存在加工效率和加工质量不可兼得的瓶颈问题。为此,研究人员提出了将激光加工和其他加工方式结合起来的复合加工方法,旨在实现硬脆性材料的高质量和高效率加工。概述了主流的基于激光复合的硬脆材料加工方法,主要包括其他方式辅助激光加工、激光辅助其他方式加工、激光辅助激光加工;重点阐述了这些激光复合加工技术的加工原理、研究现状和加工效果;总结了不同激光复合加工方法的优势、局限性和应用场景,最后对激光复合加工硬脆性材料的未来发展趋势提出了展望。

关键词：激光复合加工硬脆性材料加工效率加工质量微结构

激光诱导等离子体加工蓝宝石微结构及其润湿性

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光学精密工程 2024年第3期32卷 366-380页

作者：王晓光温秋玲陈金鸿黄国钦崔长彩姜峰华侨大学制造工程研究院福建厦门361021

激光诱导等离子体刻蚀技术在蓝宝石表面微结构制作方面具有独特的优势。通过控制变量法研究了激光能量密度、靶材和蓝宝石之间的距离和扫描速度对激光诱导等离子体加工蓝宝石微槽的微观形貌和几何尺寸的影响规律。通过正交试验研究了激... 详细信息

激光诱导等离子体刻蚀技术在蓝宝石表面微结构制作方面具有独特的优势。通过控制变量法研究了激光能量密度、靶材和蓝宝石之间的距离和扫描速度对激光诱导等离子体加工蓝宝石微槽的微观形貌和几何尺寸的影响规律。通过正交试验研究了激光诱导等离子体工艺参数对蓝宝石表面微结构接触角的影响,发现扫描线间距对接触角的影响最大,靶材和蓝宝石之间的距离和激光能量密度次之,扫描速度的影响最小。当激光能量密度为6.3 J/cm^(2),扫描线间距为200μm,靶材和蓝宝石之间的距离为150μm,扫描速度为10 mm/s时,蓝宝石表面微结构的接触角为136°,表现出良好的疏水性;当激光能量密度为7.4 J/cm^(2),扫描线间距为50μm,靶材和蓝宝石之间的距离为100μm,扫描速度为5 mm/s时,蓝宝石表面微结构的接触角为29°,具有较好的亲水性,并且长时间放置后表面接触角基本保持不变。通过扫描电镜观察发现,蓝宝石表面的微结构上分布着许多纳米颗粒,这些微纳结构共同影响蓝宝石的润湿性。

关键词：激光诱导等离子体烧蚀蓝宝石微结构工艺参数表面润湿性

能量场辅助激光诱导等离子体加工透明硬脆材料的研究现状及发展趋势

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机械工程学报 2024年第9期60卷 254-272页

作者：江安娜言兰王宁昌姜峰李卓温秋玲卢希钊黄辉华侨大学机电及自动化学院厦门361021 脆性材料产品智能制造技术国家地方联合工程研究中心厦门361021 高性能工具全国重点实验室(郑州磨料磨具磨削研究所有限公司) 郑州450000 华侨大学制造工程研究院厦门361021 高性能工具全国重点实验室(华侨大学) 厦门361021

能量场辅助激光诱导等离子体加工技术是一种新兴的制造技术。基于传统的激光加工技术,通过引入热场、电场、磁场、化学场等能场进行创新,提高激光加工过程的可控性,不仅实现了透明硬脆材料纳米级甚至亚纳米级高精度制造,也有利于满足超... 详细信息

能量场辅助激光诱导等离子体加工技术是一种新兴的制造技术。基于传统的激光加工技术,通过引入热场、电场、磁场、化学场等能场进行创新,提高激光加工过程的可控性,不仅实现了透明硬脆材料纳米级甚至亚纳米级高精度制造,也有利于满足超精密制造的高质量、低损伤要求。从热场、磁场、电场、化学场分别具体阐述了不同的能量场辅助对激光加工技术的影响,通过分析激光机理和能量场辅助机理总结热场、电场、磁场和化学场对激光加工中的热能、光能、动能和表面能的影响原理,并介绍了能量场辅助激光加工的设备及工艺方法,最后总结能量场辅助激光加工技术目前存在的不足及未来面临的挑战,为进一步发展多能场复合辅助激光诱导等离子体加工技术奠定基础。

关键词：透明硬脆材料电场辅助激光加工磁场辅助激光加工热场辅助激光加工化学场辅助激光加工

Molecular imaging:design mechanism and bioapplications

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Science China Chemistry 2023年第5期66卷 1336-1383页

作者： Lanlan Chen Yifan Lyu Xuan Zhang Liting Zheng Qingqing Li Ding Ding Fengming Chen Yihao Liu Wei Li Yutong Zhang qiuling huang Zhiqiang Wang Tiantian Xie Qiang Zhang Yingyu Sima Ke Li Shuai Xu Tianbing Ren Mengyi Xiong Ying Wu Jibin Song Lin Yuan huanghao Yang Xiao-Bing Zhang Weihong Tan Molecular Science and Biomedicine Laboratory(MBL) State Key Laboratory of Chemo/Biosensing and Chemomet-ricsCollege of Chemistry and Chemical EngineeringAptamer Engineering Center of Hunan ProvinceHunan UniversityChangsha 410082China Key Laboratory for Analytical Science of Food Safety and Biology(Ministry of Education) College of ChemistryFuzhou UniversityFuzhou 350108China College of Chemistry Beijing University of Chemical TechnologyBeijing 100029China The Cancer Hospital of the University of Chinese Academy of Sciences(Zhejiang Cancer Hospital) Institute of Basic Medicine and Cancer(IBMC)Chinese Academy of SciencesHangzhou 310022China Institute of Molecular Medicine(IMM) State Key Laboratory of Oncogenes and Related Genes Renji HospitalShanghai Jiao Tong University School of MedicineCollege of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240China College of Chemistry and Chemical Engineering Central South UniversityChangsha 410083China School of Chemistry and Chemical Engineering University of JinanJinan 250022China

Molecular imaging is a non-invasive method to image and analyze the concentration and activity of functional biomolecules in cells or in vivo at molecular level,and plays an increasing role in deep understanding of biological processes,early and accurate diagnosis of diseases,and evaluation of treatment.Nowadays,numerous novel molecular imaging probes have been developed,involving every biomedical imaging modality,such as optical imaging,photoacoustic imaging,magnetic resonance imaging,single-photon-emission computed tomography,and positron emission tomography.In this review,we summarize the development of current state-of-the-art molecular imaging probes.We introduce the design strategies of molecular probes and detailed imaging modalities,and highlight the properties of probes and biomedical imaging applications in cells and in vivo,including disease diagnosis,drug tracking,and imaging-guided surgery.Then we discuss the perspectives and challenges in this emerging field.We expect this review could inspire more effective molecular imaging probes to be developed,achieving the goal towards clinical practices.

关键词： molecular imaging imaging probes multimodality biomedical applications diseases diagnosis

PRMT5 determines the pattern of polyploidization and prevents liver from cirrhosis and carcinogenesis

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Journal of Genetics and Genomics 2023年第2期50卷 87-98页

作者： Jincheng Wang Xiang huang Daoshan Zheng qiuling Li Mei Mei Shilai Bao State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijing 100101China School of Life Sciences University of Chinese Academy of SciencesBeijing 100049China

Human hepatocellular carcinoma(HCC)occurs almost exclusively in cirrhotic livers.Here,we report that hepatic loss of protein arginine methyltransferase 5(PRMT5)in mice is sufficient to cause cirrhosis and HCC in a clinically relevant way.Furthermore,pathological polyploidization induced by hepatic loss of PRMT5 promotes liver cirrhosis and hepatic tumorigenesis in aged liver.The loss of PRMT5 leads to hyperaccumulation of P21 and endoreplication-dependent formation of pathological mono-nuclear polyploid hepatocytes.PRMT5 and symmetric dimethylation at histone H4 arginine 3(H4R3me2s)directly associate with chromatin of P21 to suppress its transcription.More importantly,loss of P21 rescues the pathological mono-nuclear polyploidy and prevents PRMT5-deficiency-induced liver cirrhosis and HCC.Thus,our results indicate that PRMT5-mediated symmetric dimethylation at histone H4 arginine 3(H4R3me2s)is crucial for preventing pathological polyploidization,liver cirrhosis and tumorigenesis in mouse liver.

关键词： Pathological polyploidizaion Hepatocellular carcinoma Cirrhosis PRMT5 Aging

A New Edge Perturbation Mechanism for Privacy-Preserving Data Collection in IOT

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Chinese Journal of Electronics 2023年第3期32卷 603-612页

作者： CHEN qiuling YE Ayong ZHANG Qiang huang Chuan College of Computer and Cyber Security Fujian Normal University Fujian Provincial Key Laboratory of Network Security and Cryptology

A growing amount of data containing the sensitive information of users is being collected by emerging smart connected devices to the center server in Internet of things(IoT) era, which raises serious privacy concerns for millions of users. However, existing perturbation methods are not effective because of increased disclosure risk and reduced data utility, especially for small data sets. To overcome this issue, we propose a new edge perturbation mechanism based on the concept of global sensitivity to protect the sensitive information in IoT data collection. The edge server is used to mask users’ sensitive data, which can not only avoid the data leakage caused by centralized perturbation, but also achieve better data utility than local perturbation. In addition, we present a global noise generation algorithm based on edge perturbation. Each edge server utilizes the global noise generated by the center server to perturb users’ sensitive data. It can minimize the disclosure risk while ensuring that the results of commonly performed statistical analyses are identical and equal for both the raw and the perturbed data. Finally, theoretical and experimental evaluations indicate that the proposed mechanism is private and accurate for small data sets.

关键词： Internet of things Edge perturbation Data privacy Sensitive attribute Statistical query

计及杂散参数的柔性直流启动电阻冲击电压分布特性研究

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高压电器 2024年第6期60卷 156-165页

作者：周竞宇张文博韩坤洪波胡秋玲黄永瑞中国南方电网有限责任公司超高压输电公司广州510620 许继集团有限公司河南许昌461000 许继电气股份有限公司河南许昌461000

针对柔性直流输电系统中启动电阻异常放电问题。首先,从启动电阻温升、绝缘水平、电流应力及冲击能量几方面进行校核分析;然后,对现场启动电阻进行拆解,定量分析启动电阻放电原因;最后,利用Ansys搭建电阻器杂散电容求解模型,根据分布电... 详细信息

针对柔性直流输电系统中启动电阻异常放电问题。首先,从启动电阻温升、绝缘水平、电流应力及冲击能量几方面进行校核分析;然后,对现场启动电阻进行拆解,定量分析启动电阻放电原因;最后,利用Ansys搭建电阻器杂散电容求解模型,根据分布电容求解结果,基于PSCAD搭建电阻塔的宽频等效模型,仿真分析启动电阻在冲击电压下的电位分布规律,验证启动电阻异常放电机理并提出优化改进措施。研究结果可为今后柔性直流输电系统启动电阻的选型设计提供参考。

关键词：柔直系统启动电阻杂散参数电位分布放电分析