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Rare Metals 2023年第4期42卷 1205-1213页

作者： Geng Tan yu-qiong Guo Lu-Yang Zuo Ka zhang Yi-Ming zhang Li-Lei zhang Jing-Jing yu Xun Feng Bo Li Li-Ya Wang College of Chemistry and Pharmaceutical Engineering Nanyang Normal UniversityNanyang473061China College of Chemistry and Chemical Engineering Luoyang Normal UniversityLuoyang471934China

In the present work,a zinc-based metal-organic framework{[Zn(ddpd)_(0.5)(bipy)_(0.5)]·H_(2)O]}_(n)(1-Zn)(where ddpd=2,5-di(2',4'-dic arboxylphenyl)-1,4-difluorobenzene,bipy=4,4-bipyridine)was synthesized by a solvothermal *** 1-Zn features a threedimensional(2,4,6)-connected network with{4^2.6^2.8^2}_(2){4^4.6^6.8^5}{6}***,without the assistance of other reagents,complex 1-Zn not only exhibited an exceeded 95%photodegradation efficiency for rhodamine B(Rh B),methyl blue(MB)and methyl orange(MO)within 40 min,but also showed high stability and *** addition,free radical quenching experiments and electron spin resonance(ESR)spectroscopy verified that the main active species in the photodegradation process were·O_(2)^(-)and OH,and a more indepth degradation mechanism was further elucidated by density functional theory(DFT)calculations.

关键词： Zinc Metal-organic frameworks(MOFs) ·O_(2)^(-) ·OH Photodegradation

Dynamic Characteristics Analysis and Vibration Experiment of Upper-time of Flight Counter (U-ToFC)

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Chinese Journal of Mechanical Engineering 2012年第5期25卷 868-874页

作者： WU qiong zhang Yidu SONG Sunguang State Key Lab of Virtual Reality Technology and Systems Beihang UniversityBeijing 100191China School of Mechanical Engineering andAutomation Beihang UniversityBeijing 100191China

The dynamic characteristic parameters of Up-time of Flight Counter （U-ToFC） are important for research of structure optimization and reliability. However, the current simulation is performed based on homogenous material and simplified constraint model, the correct and reliability of results are difficult to be guaranteed. The finite element method based on identification of material parameters is proposed for this investigation on dynamic analysis, simulation and vibration experiment of the U-ToFC. The structure of the U-ToFC is complicated. Its＇ outside is made of aluminum alloy and inside contains electronic components such as capacitors, resistors, inductors, and integrated circuits. The accurate material parameters of model are identified difficultly. Hence, the parameters identification tests are performed to obtain the material parameters of this structure. On the basis of the above parameters, the experiment and FEA are conducted to the U-ToFC. In terms of the flight acceptance test level, and two kinds of joints condition between the U-ToFC and fixture are considered. The natural frequencies, vibration shapes and the response of the power spectral density of the U-ToFC are obtained. The results show simulation which is based on parameters identification is similar with vibration experiment in natural frequencies and responses. The errors are less than 10%. The vibration modes of simulation and experiment are consistent. The paper provides a more reliable computing method for the dynamic characteristic analysis of large complicated structure.

关键词： random vibration dynamical characteristic parameters finite element analysis identification of material parameters

Transfer RNA-derived small RNA serves as potential non-invasive diagnostic marker and a novel therapeutic target for acute pancreatitis

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World Journal of Gastroenterology 2025年第1期31卷 152-156页

作者： Jing zhang Chun-Lin Ou Department of Immunology School of Basic MedicineCentral South UniversityChangsha 410000Hunan ProvinceChina Department of Pathology Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina

Transfer RNA(tRNA)-derived fragments,a new type of tRNA-derived small RNA(tsRNA),can be cleaved from tRNA by enzymes to regulate target gene expression at the transcriptional and translational *** are not only degradation fragments but also have biological functions,including those in immune inflammation,metabolic disorders,and cell *** dysregulation is closely associated with multiple diseases,including various cancers and acute pancreatitis(AP).AP is a common gastrointestinal disease,and its incidence increases *** development is associated with tsRNAs,which regulate cell injury and induce inflammation,especially pyroptosis and ***,serum tRF36 has the potential to serve as a non-invasive diagnostic biomarker and leads to pancreatic acinar cell ferroptosis causing inflammation to promote *** show the characteristics of tsRNAs and their diagnostic value and function in AP,and discuss the potential opportunities and challenges of using tsRNAs in clinical applications and research.

关键词： Transfer RNA derived small RNAs Acute pancreatitis Liquid biopsy Biomarker Cell pyroptosis Ferroptosis

Targeting Epac2 and GluA3-containing AMPARs:a novel therapeutic strategy for Alzheimer's disease

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Neural Regeneration Research 2025年第11期20卷 3223-3224页

作者： Tong zhang Martina Schmidt Department of Molecular Pharmacology Groningen Research Institute of PharmacyUniversity of GroningenGroningenThe Netherlands School of Pharmacy Tianjin Medical UniversityTianjinChina

Alzheimer's disease(AD)is a neurodegenerative disease that manifests progressive decline in memory and *** the early stage of AD,memory retrieval is impaired preceding memory acquisition and consolidation(Roy et al.,2016).Prior to the onset of symptoms,pathological amyloid-β(Aβ)plagues and tau protein tangles accumulate in extracellular and intracellular spaces,respectively,leading to *** these hallmark pathologies,Aβ is proposed to be the primary etiology by triggering a cascade of pathogenic events,including neuroinflammation,oxidative stress,tau hyperphosphorylation,synaptic/neuronal dysfunction,and neuronal death(zhang et al.,2023b).

关键词： Alzheimer impaired Aβ

Evaluating Optimal Treatment for Melanoma:A Network Meta-Analysis

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Chinese Journal of Plastic and Reconstructive Surgery 2021年第1期3卷 27-31页

作者： Mengyuan zhang qiong HE yuifang yu Baolin zhang Department of Plastic Surgery First Hospital of Shanxi Medical UniversityTaiyuanShanxi 030001China Department of Endocrinology.First Hospital of Shanxi Medical University TaiyuanShanxi 030001China

Background It is necessary to determine the optimal treatment for melanoma as the incidence of melanoma is increasing every *** this study,we conducted a metaanalysis to compare the effectiveness of available treatments for *** The index keywords“melanoma”and“treatment”were used to search the PubMed,Cochrane Library,Web of Science,and Embase databases,and the articles were limited to randomized controlled *** search was filtered for articles published until February 2020,and articles were independently extracted by two *** metaanalysis(Stata®14.0 software network package,StataCorp LLC,TX,USA)was used to compare the effectiveness of the mentioned treatments of *** A total of 616 articles were screened of which 6 were selected for meta-analysis,involving 5 treatment measures and 2047 patients(those who were not followed up on were excluded).The treatment strategies reported for melanoma included tumor necrosis factor(L19-TNFα)and interleukin-2(L19IL2)in combination with dacarbazine(L19IL2+DTIC),DTIC,programmed cell death-1 plus cytotoxic T cell antigen-4(PD-1+CTLA-4),PD-1,and *** Among L19IL2+DTIC,DTIC,PD-1+CTLA-4,PD-1,and CTLA-4,CTLA-4 is found to be the best treatment method for *** study findings provide a reference for the clinical treatment of melanoma and can clarify the direction for setting up controlled clinical trials.

关键词： Melanoma treatment Network Meta-analysis

Evolution and phylogenetic application of the MC1R gene in the Cobitoidea(Teleostei: Cypriniformes)

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Zoological Research 2016年第5期37卷 281-289页

作者： qiong-Ying TANG Li-Xia SHI Fei LIU Dan yu Huan-zhang LIU The Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences Institute of Hydrobiology Chinese Academy of Sciences Wuhan 430072 China University of Chinese Academy of Sciences Beijing 100049 China

Fish of the superfamily Cobitoidea sensu stricto （namely Ioaches） exhibit extremely high diversity of color patterns, but so far little is known about their evolutionary mechanism. Melanocortin 1 receptor gene （MCIR） plays an important role during the synthesis of melanin and formation of animal body color patterns. In this study, we amplified and sequenced the partial MCIR gene for 44 loach individuals representing 31 species of four families. Phylogenetic analyses yielded a topology congruent with previous studies using multiple nuclear loci, showing that each of the four families was monophyletic with sister relationships of Botiidae＋（Cobitidae＋（Balitoridae＋Nemacheilidae））. Gene evolutionary analyses indicated that MCIR in Ioaches was under purifying selection pressure, with various sites having different dNIds values. Both Botiidae and Cobitidae had lower dN/ds values than those of background lineages, suggesting their evolution might be strongly affected by purifying selection pressure. For Balitoddae and Nemacheilidae, both had larger dNIds values than those of background lineages, suggesting they had a faster evolutionary rate under more relaxed selection pressure. Consequently, we inferred that the relatively stable color patterns in Botiidae and Cobitidae might result from the strong purifying selection pressure on the MC1R gene, whereas the complicated and diverse color patterns in Balitoridae and Nemacheilidae might be associated with the relaxed selection pressure. Given the easy experimental procedure for the partial MCTR gene and its excellent performance in reconstructing phylogeny, we suggest this gene could be used as a good molecular marker for the phylogenetic study of fish species.

关键词： Gene evolution Molecular phylogeny Cobitoidea Melanocortin 1 receptor gene

Fundamental Characteristics of Tropical Rain Cell Structures as Measured by TRMM PR

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Journal of Meteorological Research 2020年第6期34卷 1129-1150页

作者： yunfei FU Yilun CHEN Xiangdong zhang yu WANG Rui LI Qi LIU Lei ZHONG qiong zhang Aoqi zhang School of Earth and Space Sciences University of Science and Technology of ChinaHefei 230026China International Arctic Research Center and Department of Atmospheric Sciences University of Alaska FairbanksFairbanksAK 99775USA Department of Physical Geography and Bolin Center for Climate Research Stockholm UniversityStockholm 10691Sweden

Rain cells are the most elementary unit of precipitation system in *** this study,fundamental geometric and physical characteristics of rain cells over tropical land and ocean areas are investigated by using 15-yr measurements of the Tropical Rainfall Measuring Mission(TRMM)Precipitation Radar(PR).The rain cells are identified with a minimum bounding rectangle(MBR)*** results indicate that about 50%of rain cells occur at length of about 20 km and width of 15 *** proportion of rain cells with length>200 km and width>100 km is less than1%.There is a a log-linear relationship between the mean length and width of rain ***,for the same horizontal geometric parameters,rain cells tend to be square horizontally and lanky vertically over land,while vertically squatty over *** rainfall intensity of rain cells varies from 0.4 to 10 mm h-1 over land to 0.4–8 mm h-1 over *** results indicate that the occurrence frequency of rain cells decreases as the areal fraction of convective precipitation in rain cells increases,while such frequency remains almost invariant when the areal fraction of stratiform precipitation varies from 10%to 80%.The relationship between physical and geometric parameters of rain cells shows that the mean rain rate of rain cells is more frequently associated with the increase of their area,with the increasing rate over land greater than that over *** results also illustrate that heavy convective rain rate prefers to occur in larger rain cells over land while heavy stratiform rain rate tends to appear in larger rain cells over *** the same size of rain cells,the areal fraction and the contribution of convective precipitation are about10%–15%higher over land than over ocean.

关键词： rain cell occurrence frequency geometric parameters physical parameters Tropical Rainfall Measuring Mission(TRMM)Precipitation Radar(PR)

Amorphous phosphorus chalcogenide as an anode material for lithiumion batteries with high capacity and long cycle life

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Journal of Energy Chemistry 2022年第5期31卷 658-668页

作者： Jiale yu Haiyan zhang Yingxi Lin Junyao Shen Yiwen Xie Xifeng Huang qiong Cai Haitao Huang School of Materials and Energy Guangdong University of TechnologyGuangzhou 510006GuangdongChina Department of Chemical and Process Engineering University of SurreyGuildford GU27XHUK Department of Applied Physics The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong 999077China

The ever-increasing demands for modern energy storage applications drive the search for novel anode materials of lithium(Li)-ion batteries(LIBs) with high storage capacity and long cycle life, to outperform the conventional LIBs anode materials. Hence, we report amorphous ternary phosphorus chalcogenide(aP_(4)SSe_(2)) as an anode material with high performance for LIBs. Synthesized via the mechanochemistry method, the a-P_(4)SSe_(2) compound is endowed with amorphous feature and offers excellent cycling stability(over 1500 mA h g^(-1) capacity after 425 cycles at 0.3 A g^(-1)), owing to the advantages of isotropic nature and synergistic effect of multielement forming Li-ion conductors during battery operation. Furthermore,as confirmed by ex situ X-ray diffraction(XRD) and transmission electron microscope(TEM), the a-P_(4)SSe_(2)anode material has a reversible and multistage Li-storage mechanism, which is extremely beneficial to long cycle life for batteries. Moreover, the autogenous intermediate electrochemical products with fast ionic conductivity can facilitate Li-ion diffusion effectively. Thus, the a-P_(4)SSe_(2)electrode delivers excellent rate capability(730 mA h g^(-1)capacity at 3 A g^(-1)). Through in situ electrochemical impedance spectra(EIS) measurements, it can be revealed that the resistances of charge transfer(R_(SEI)) and solid electrolyte interphase(R_(Ct)) decrease along with the formation of Li-ion conductors whilst the ohmic resistance(R_(Ω)) remains unchanged during the whole electrochemical process, thus resulting in rapid reaction kinetics and stable electrode to obtain excellent rate performance and cycling ability for LIBs. Moreover, the formation mechanism and electrochemical superiority of the a-P_(4)SSe_(2)phase, and its expansion to P_(4)S_(3-x)Se_(x)(x = 0, 1, 2, 3) family can prove its significance for LIBs.

关键词： Lithium-ion batteries Amorphous anode materials Lithium ionic conductor High capacity Long cycle life

Microstructural evolution during the progressive transformation-induced plasticity effect in a Fe-0.1C-5Mnmedium manganese steel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 369-379页

作者： Mei zhang Wenhao Li Yangfei Chen Yang Jiang Xiaofei Guo Han Dong School of Materials Science and Engineering Shanghai UniversityShanghai 200444China State Key Laboratory of Advanced Special Steel Shanghai UniversityShanghai 200444China

The microstructural evolution of a cold-rolled and intercritical annealed medium-Mn steel(Fe-0.10C-5Mn)was investigated during uniaxial tensile ***-situ observations under scanning electron microscopy,transmission electron microscopy,and X-ray diffraction analysis were conducted to characterize the progressive transformation-induced plasticity process and associated fracture initiation *** findings were discussed with the local strain measurements via digital image *** results indicated that Lüders band formation in the steel was limited to 1.5%strain,which was mainly due to the early-stage martensitic phase transformation of a very small amount of the less stable large-sized retained austenite(RA),which led to localized stress concentrations and strain hardening and further retardation of *** small-sized RA exhibited high stability and progressively transformed into martensite and contributed to a stably extended Portevin-Le Chatelier *** volume fraction of RA gradually decreased from 26.8%to 8.2%prior to *** the late deformation stage,fracture initiation primarily occurred at the austenite/martensite and ferrite/martensite interfaces and the ferrite phase.

关键词： medium-Mn steel retained austenite progressive transformation-induced plasticity effect local strain fracture initiation

Ammonia pyrolysis oxidation excited by nanosecond pulsed discharge:Global/fluid models hybrid solution

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Journal of Energy Chemistry 2025年第1期100卷 385-396页

作者： Mingming zhang Hanyu Wu Qi Chen Jiaxin Yang Bonan Liu School of Mechanical Electronic and Control Engineering Beijing Jiaotong University China University of Petroleum

The kinetic characteristics of plasma-assisted oxidative pyrolysis of ammonia are studied by using the global/fluid models hybrid solution ***,the stable products of plasma-assisted oxidative pyrolysis of ammonia are *** results show that the consumption of NH3/O2and the production of N2/H2change linearly with the increase of voltage,which indicates the decoupling of nonequilibrium molecular excitation and oxidative pyrolysis of ammonia at low ***,the detailed reaction kinetics mechanism of ammonia oxidative pyrolysis stimulated by a nanosecond pulse voltage at low pressure and room temperature is *** on the reaction path analysis,the simplified mechanism is *** detailed and simplified mechanism simulation results are compared with experimental data to verify the accuracy of the simplified ***,based on the simplified mechanism,the fluid model of ammonia oxidative pyrolysis stimulated by the nanosecond pulse plasma is established to study the pre-sheath/sheath behavior and the resultant consumption and formation of key *** results show that the generation,development,and propagation of the pre-sheath have a great influence on the formation and consumption of *** consumption of NH3by the cathode pre-sheath is greater than that by the anode pre-sheath,but the opposite is true for OH and O（1S）.However,within the sheath,almost all reactions do not ***,by changing the parameters of nanosecond pulse power supply voltage,it is found that the electron number density,electron current density,and applied peak voltages are not the direct reasons for the structural changes of the sheath and ***,the discharge interval has little effect on the sheath structure and gas mixture *** research results of this paper not only help to understand the kinetic promotion of non-equilibrium excitation in the process of oxidative pyrolysis but also help to explore th

关键词： Nanosecond pulsed discharge Ammonia Oxidative pyrolysis Fluid model Global model