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Magnetism of NaYbS: From finite temperatures to ground state

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Science China(Physics,Mechanics & Astronomy) 2024年

作者： Weizhen Zhuo Zheng Zhang Mingtai Xie Anmin Zhang jianting ji Feng jin qingming Zhang School of Physical Science and Technology Lanzhou University Beijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences

Rare-earth chalcogenide compounds ARECh2（A = alkali or monovalent metal, RE = rare earth, Ch = O, S, Se, Te） are a large family of quantum spin liquid（QSL） candidate materials. NaYbS2is a representative member of the family. Several key issues on NaYbS2, particularly how to determine the highly anisotropic spin Hamiltonian and describe the magnetism at finite temperatures and the ground state, remain to be addressed. In this paper, we conducted an in-depth and comprehensive study on the magnetism of NaYbS2from finite temperatures to the ground state. Firstly, we successfully detected three crystalline electric field（CEF） excitation energy levels using low-temperature Raman scattering technique. Combining them with the CEF theory and magnetization data, we worked out the CEF parameters, CEF energy levels, and CEF wavefunctions. We further determined a characteristic temperature of ～40 K, above which the magnetism is dominated by CEF excitations while below which the spinexchange interactions play a main role. The characteristic temperature has been confirmed by the temperature-dependent electron spin resonance（ESR） linewidth. Low-temperature ESR experiments on the dilute magnetic doped crystal of NaYb0.1Lu0.9S2further helped us to determine the accurate g-factor. Next, we quantitatively obtained the spin-exchange interactions in the spin Hamiltonian by consistently simulating the magnetization and specific heat data. Finally, the above studies allow us to explore the ground state magnetism of NaYbS2by using the density matrix renormalization group. We combined numerical calculations and experimental results to demonstrate that the ground state of NaYbS2is a Dirac-like QSL.

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Flavonoids from mulberry leaves inhibit fat production and improve fatty acid distribution in adipose tissue in finishing pigs

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Animal Nutrition 2024年第1期16卷 147-157页

作者： Yingying Liu Yinglin Peng Chen Chen Huibo Ren ji Zhu Yuan Deng qingming Cui Xionggui Hu jianhua He Huali Li Xinghui Zhu Yulong Yin Jun He Yi Xiao College of Animal Science and Technology Hunan Agricultural UniversityChangsha410128China Hunan Institute of Animal and Veterinary Science Changsha410131China Key Laboratory of Conservation and Genetic Analysis of Local Pig Breed Germplasm Resources Changsha410131China College of Information and Intelligence Hunan Agricultural UniversityChangsha410128China Institute of Subtropical Agriculture Chinese Academy of SciencesChangsha410125China

This study evaluated the effects of flavonoids from mulberry leaves(FML)on plasma biochemical indices,serum activities of lipid metabolism-related enzymes,fat morphology,fatty acid composition,and lipid metabolism in different adipose tissues of finishing *** used 120 Chinese hybrid barrows of Berkshire and Bama mini-pigs with an average initial body weight of 45.11±4.23 *** pigs were randomly assigned to five treatment groups and fed a control diet based on corn,soybean meal,and wheat bran or a control diet supplemented with 0.02%,0.04%,0.08%,or 0.16%*** experimental group had six replicates(pens),with four pigs per *** a 7-d adaptation period,the feeding trial was conducted for 58 *** and adipose tissue samples were collected from 30 pigs(one pig per pen)at the end of the *** results showed that FML supplementation significantly decreased the feed intake to body gain ratio,the plasma concentrations of total cholesterol and free fatty acids,and the serum activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase(linear or quadratic effects,P<0.05),and decreased the plasma triglyceride concentration(quadratic,P=0.07).Increasing FML supplementation increased the average daily gain and serum activities of lipoprotein lipase(linear and quadratic effects,P<0.05)and adipose triglyceride lipase(linear,P<0.05).Dietary FML supplementation decreased the adipocyte area in the dorsal subcutaneous adipose(DSA)tissue of finishing pigs(linear,P=0.05)and increased the adipocyte area in the visceral adipose tissue(quadratic,P<0.01).Increasing FML supplementation decreased the C20:1 content in DSA,abdominal subcutaneous adipose,and visceral adipose tissues of finishing pigs(P<0.05)and increased the C18:3n3 and n-3 PUFA contents(P<0.05).The lipid metabolism genes were regulated by the PPARγ-LXRa-ABCA1 signaling pathway,and their expressions differed in different adipose *** findings suggest that FML improved growth performance,regulated lipid met

关键词： Finishing pig Mulberry leaf Flavonoid Lipid metabolism Fatty acid Lard

Porous polyetheretherketone microcarriers fabricated via hydroxylation together with cellderived mineralized extracellular matrix coatings promote cell expansion and bone regeneration

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Regenerative Biomaterials 2021年第2期8卷 149-162页

作者： Shuo Sun Zixue jiao Yu Wang Zhenxu Wu Haowei Wang qingming ji Yi Liu Zongliang Wang Peibiao Zhang Department of Spine Surgery The First Hospital of Jilin University1 Xinmin StreetChangchun 130021China Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of Sciences5625 Renmin StreetChangchun 130022China

Porous microcarriers have aroused increasing attention recently by facilitating oxygen and nutrient transfer,supporting cell attachment and growth with sufficient cell seeding *** this study,porous polyetheretherketone(PEEK)microcarriers coated with mineralized extracellular matrix(mECM),known for their chemical,mechanical and biological superiority,were developed for orthopedic *** PEEK microcarriers were derived from smooth microcarriers using a simple wet-chemistry strategy involving the reduction of carbonyl *** treatment simultaneously modified surface topology and chemical ***,the microstructure,protein absorption,cytotoxicity and bioactivity of the obtained porous microcarriers were *** deposition of mECM through repeated recellularization and decellularization on the surface of porous MCs further promoted cell proliferation and osteogenic ***,the mECM coated porous microcarriers exhibited excellent bone regeneration in a rat calvarial defect repair model in vivo,suggesting huge potential applications in bone tissue engineering.

关键词： polyetheretherketone porous microcarriers mineralized extracellular matrix cell expansion bone regeneration

Biomimetic polyetheretherketone microcarriers with specific surface topography and self-secreted extracellular matrix for large-scale cell expansion

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Regenerative Biomaterials 2020年第1期7卷 109-118页

作者： qingming ji ZongliangWang Zixue jiao Yu Wang Zhenxu Wu Peng Wang Yuhang Zhu Shuo Sun Yi Liu Peibiao Zhang Department of Spine Surgery The First Hospital of Jilin UniversityChangchun 130021PR China Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022PR China University of Science and Technology of China Hefei 230026PR China Department of Orthopedics China-Japan Union HospitalJilin UniversityChangchun 130033PR China

Reusable microcarriers with appropriate surface topography,mechanical properties,as well as biological modification through decellularization facilitating repeated cell culture are crucial for tissue engineering ***,we report the preparation of topological polyetheretherketone(PEEK)microcarriers via gas-driven and solvent exchange method followed by hydrothermal treatment at high temperature and *** hydrothermal treated for 8 h,the resulting topological PEEK microcarriers exhibit walnut-like surface topography and good sphericity as well as uniform size distribution of 350.24619.44 *** the average width between ravine-patterned surface of PEEK microcarriers is 7806290 *** repeated steam sterilization by autoclaving for three times,topological PEEK microcarriers show nearly identical results compared with previous ones indicating strong tolerance to high temperature and *** is a unique advantage for large-scale cell expansion and clinical ***,PEEK microcarriers with special topography possess higher protein adsorption *** addition,the reutilization and biofunctionalization with repeated decellularization of topological PEEK microcarriers show highly beneficial for cell adhesion and ***,our study is of great importance for new generation microcarriers with micro-and nano-scale surface feature for a broad application prospect in tissue engineering.

关键词： PEEK topological microcarriers recycle decellularization cell adhesion

宫颈鳞癌组织中肿瘤转移基因1、上皮钙黏素mRNA的表达

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郑州大学学报（医学版） 2008年第3期43卷 563-565页

作者：吉庆明河南省胸科医院郑州450008

目的:探讨肿瘤转移基因1(MTA1)、上皮钙黏素(E-cadherin)mRNA表达与宫颈鳞癌发生发展及转移的关系。方法:应用原位杂交方法检测52例宫颈鳞癌组织、34例宫颈上皮内瘤变(CIN)组织和28例正常宫颈上皮组织中MTA1、E-cadherin mRNA的表达。结... 详细信息

目的:探讨肿瘤转移基因1(MTA1)、上皮钙黏素(E-cadherin)mRNA表达与宫颈鳞癌发生发展及转移的关系。方法:应用原位杂交方法检测52例宫颈鳞癌组织、34例宫颈上皮内瘤变(CIN)组织和28例正常宫颈上皮组织中MTA1、E-cadherin mRNA的表达。结果:①宫颈鳞癌组织、CIN组织和正常宫颈黏膜组织中MTA1 mRNA的阳性表达率分别为88.5%(46/52)、63.6%(21/34)和7.1%(2/28),差异有统计学意义(P<0.05);宫颈鳞癌组织、CIN组织和正常宫颈黏膜组织中E-cadherin mRNA的阳性表达率分别为44.2%(23/52)、55.9%(19/34)和100.0%(28/28),差异亦有统计学意义(P<0.05)。②有淋巴结转移组MTA1 mRNA阳性表达率高于无淋巴结转移组(P<0.05);有淋巴结转移组E-cadherin mRNA阳性表达率低于无淋巴结转移组(P<0.05)。③宫颈鳞癌组织中MTA1与E-cadherin mRNA的表达呈负相关(r=-0.284,χ2=4.204,P<0.05)。结论:MTA1 mRNA的高表达及E-cadherin mRNA表达缺失与宫颈鳞癌的发生发展及转移有关。

关键词：宫颈肿瘤鳞状细胞癌肿瘤转移基因1 上皮钙黏素

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计算机教学中渗透道德教育的策略刍探

成才之路 2020年第6期 20-21页

作者：姬庆明甘肃省通渭县陇山学校甘肃通渭743318

小学阶段让学生打好思想道德基础,对他们今后的学习和发展有很好的促进作用。文章分析计算机教学中渗透道德教育的重要性,探讨计算机教学中渗透道德教育的策略,以提高学生的道德素质,将他们培养成为德才兼备的优秀人才。

关键词：计算机教学道德教育学习兴趣综合素质

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对鼻腔淋巴瘤形态学及免疫组化表型的研究

医药论坛杂志 2008年第3期29卷 6-7页

作者：吉庆明河南省胸科医院病理科郑州市450008

目的鼻腔是结外常发生淋巴瘤的部位之一。为探讨鼻腔淋巴瘤的形态学改变及临床特点及临床预后。方法应用免疫组化方法及临床随访对42例鼻腔恶性淋巴瘤进行了组织学类型及临床治疗方法和预后的研究。结果发现鼻腔恶性淋巴瘤以NK/T细胞淋... 详细信息

目的鼻腔是结外常发生淋巴瘤的部位之一。为探讨鼻腔淋巴瘤的形态学改变及临床特点及临床预后。方法应用免疫组化方法及临床随访对42例鼻腔恶性淋巴瘤进行了组织学类型及临床治疗方法和预后的研究。结果发现鼻腔恶性淋巴瘤以NK/T细胞淋巴瘤为主(21例),其次是T细胞淋巴瘤(非特异型)(9例),以及其他类型,弥漫性大B细胞淋巴瘤(3例),粘膜相关淋巴瘤(3例),浆细胞肉瘤(1例),粒细胞肉瘤(2例)。结论鼻腔可发生的淋巴瘤种类较多,其生物学行为存在较大差异,各类淋巴瘤其免疫表型各有其特点,是病理诊断的重要依据和鉴别诊断要点,同时是临床治疗的前提。

关键词：鼻腔恶性淋巴瘤组织形态学免疫组化表型

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新辅助化疗后乳腺癌的临床病理学变化及意义

中国实用医刊 2008年第16期35卷 7-9页

作者：吉庆明河南省胸科医院郑州450008

目的观察乳腺癌新辅助化疗后的临床病理学改变及意义。方法60例局部进展期乳腺癌均经空心针穿刺获取组织学证实为乳腺癌，并作免疫组化行ER、PR、cerb—B2、P53、Topo～Ⅱ检测，新辅助化疗采用FEC常规化疗方案，完成4周期新辅助化疗后... 详细信息

目的观察乳腺癌新辅助化疗后的临床病理学改变及意义。方法60例局部进展期乳腺癌均经空心针穿刺获取组织学证实为乳腺癌，并作免疫组化行ER、PR、cerb—B2、P53、Topo～Ⅱ检测，新辅助化疗采用FEC常规化疗方案，完成4周期新辅助化疗后进行临床疗效评价。对术后标本进行常规HE、免疫组织化学染色观察。结果总有效率（RR）为91．66％（55／60），临床完全缓解率（cCR）为28．33％（17／60），临床部分缓解率（cPR）为63．33％（38／60），无变化（NC）8．33％（5／60），无疾病进展患者。其中病理完全缓解率（pCR）为23．33％（14／60），行保乳手术16例，保乳率为26．67％（16／60）。与术前病理活检标本比较，新辅助化疗后瘤体缩小变软、甚至消失，肿瘤细胞退变坏死，化疗后乳腺癌标本间质水肿、间质增生胶原化明显，癌旁乳腺组织部分导管上皮可呈轻-中度异型性；淋巴结无论有无转移均可见结构改变，转移淋巴结内可见肿瘤细胞退变坏死、间质炎细胞浸润及纤维化等。免疫组织化学未见ER、PR表达变化，cerb—B2、P53、Topo-Ⅱ表达差异无统计学意义。结论FEC新辅助化疗使多数乳腺癌原发灶及淋巴结转移灶出现不同程度变性坏死，提高手术率并增加了保乳机会，在术后辅助治疗及判断预后方面具有重要临床意义。

关键词：乳腺癌新辅助化疗病理组织学免疫组化

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组织蛋白酶B在人胶质瘤组织中的表达及意义

中国实用神经疾病杂志 2008年第3期11卷 49-51页

作者：吉庆明河南省胸科医院郑州450008

目的探讨组织蛋白酶B(CB)在人胶质瘤组织中的表达及其临床意义。方法应用免疫组化SP法检测57例人胶质瘤组织和24例正常脑组织中CB的蛋白表达。结果正常脑组织及人胶质瘤组织中CB蛋白的阳性表达率分别为92.98%(53/57)和16.67%(6/24),两... 详细信息

目的探讨组织蛋白酶B(CB)在人胶质瘤组织中的表达及其临床意义。方法应用免疫组化SP法检测57例人胶质瘤组织和24例正常脑组织中CB的蛋白表达。结果正常脑组织及人胶质瘤组织中CB蛋白的阳性表达率分别为92.98%(53/57)和16.67%(6/24),两者相比,差异有统计学意义(P<0.05);CB蛋白在正常脑组织及人胶质瘤组织中的相对表达量分别为(6.31±0.42)和(13.56±0.34),两者相比,差异亦有统计学意义(P<0.05);随着肿瘤级别升高CB蛋白的相对表达量亦升高(P<0.05)。结论CB蛋白表达与人胶质瘤的发生发展有关。

关键词：人胶质瘤组织蛋白酶B 蛋白表达免疫组化