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Decellularized extracellular matrix mediates tissue construction and regeneration

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Frontiers of Medicine 2022年第1期16卷 56-82页

作者： Chuanqi liu Ming Pei qingfeng li Yuanyuan Zhang Department of Plastic and Burn Surgery West China HospitalSichuan UniversityChengdu 610041China Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China Stem Cell and Tissue Engineering Laboratory Department of OrthopaedicsWest Virginia UniversityMorgantownWV 26506USA Wake Forest Institute for Regenerative Medicine Wake Forest University Health SciencesWinston-SalemNC 27109USA

Contributing to organ formation and tissue regeneration,extracellular matrix(ECM)constituents provide tissue with three-dimensional(3D)structural integrity and cellular-function *** the crucial traits of the cellular microenvironment,ECM substitutes mediate cell–matrix interactions to prompt stem-cell proliferation and differentiation for 3D organoid construction in vitro or tissue regeneration in ***,these ECMs are often applied generically and have yet to be extensively developed for specific cell types in 3D *** cells also produce rich ECM,particularly stromal *** ECM improves 3D culture development in vitro and tissue remodeling during wound healing after implantation into the host as *** better insight into ECM derived from either tissue or cells that regulate 3D tissue reconstruction or organ regeneration helps us to select,produce,and implant the most suitable ECM and thus promote 3D organoid culture and tissue remodeling for in vivo ***,the decellularization methodologies and tissue/cell-derived ECM as scaffolds or cellular-growth supplements used in cell propagation and differentiation for 3D tissue culture in vitro are ***,current preclinical applications by which ECM components modulate the wound-healing process are reviewed.

关键词： decellularized extracellular matrix 3D culture organoids tissue repair

Influence of the time-step on the production of free nucleons and pions from heavy-ion collisions around 1 GeV/nucleon

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Science China(Physics,Mechanics & Astronomy) 2016年第12期59卷 40-46页

作者： liYan Zou Miao li ChenChen Guo YongJia Wang qingfeng li ling liu School of Science Huzhou University College of Physics Science and Technology Shenyang Normal University Shanghai Institute of Applied Physics Chinese Academy of Sciences Institute of Modern Physics Chinese Academy of Sciences

By considering different values of the time-step for the potential updates in the ultra-relativistic quantum molecular dynamics(UrQMD) model, we examine its influence on observables, such as the yield and collective flow of nucleons and pions from heavyion collisions around 1 GeV/nucleon. It is found that these observables are affected to some extent by the choice of the time-step,and the impact of the time-step on the pion-related observables is more visible than that on the nucleon-related ones. However,its effect on the π-/π+yield ratio and elliptic flow difference between neutrons and protons, which have been taken as sensitive observables for probing the density-dependent nuclear symmetry energy at high densities, is fairly weak.

关键词： UrQMD model symmetry energy at supranormal densities mean-field potential updates

Hydrogen as a carrier of renewable energies toward carbon neutrality:State-of-the-art and challenging issues

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International Journal of Minerals,Metallurgy and Materials 2022年第5期29卷 1073-1089页

作者： Xuan liu Gaoyang liu Jilai Xue Xindong Wang qingfeng li Department of Energy Conversion and Storage Technical University of DenmarkFysikvej 3102800 Kgs.LyngbyDenmark School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

Energy storage and conversion via a hydrogen chain is a recognized vision of future energy systems based on renewables and,therefore,a key to bridging the technological gap toward a net-zero CO_(2)emission *** paper reviews the hydrogen technological chain in the framework of renewables,including water electrolysis,hydrogen storage,and fuel cell *** electrolysis is an energy conversion technology that can be scalable in megawatts and operational in a dynamic mode to match the intermittent generation of renewable *** concerns include a robust diaphragm for alkaline cells,catalysts and construction materials for proton exchange membrane(PEM)cells,and validation of the long-term durability for solid oxide *** storage via compressed gas up to 70 MPa is optional for automobile *** cells favor hydrogen fuel because of its superfast electrode *** fuel cells and solid oxide fuel cells are dominating technologies for automobile and stationary applications,*** technologies are at the threshold of their commercial markets with verified technical readiness and environmental merits;however,they still face restraints such as unavailable hydrogen fueling infrastructure,long-term durability,and costs to compete with the analog power technologies already on the market.

关键词： carbon neutrality hydrogen energy water electrolysis hydrogen storage fuel cells

The effect of symmetry potential on the balance energy of light particles emitted from mass symmetric heavy-ion collisions with isotopes,isobars and isotones

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Science China(Physics,Mechanics & Astronomy) 2012年第12期55卷 2407-2413页

作者： WANG YongJia GUO ChenChen li qingfeng ZHANG HongFei School of Science Huzhou Teachers CollegeHuzhou 513000China School of Nuclear Science and Technology Lanzhou University Lanzhou 730000China College of Nuclear Science and Technology Beijing Normal UniversityBeijing 100875China

Using the Ultrarelativistic Quantum Molecular Dynamics(UrQMD) model,the balance energies of free neutrons,free protons and Z=1 particles(including free protons,deuterons and tritons) from mass symmetric heavy-ion collisions with isotopes,isobars and isotones are *** influence of nuclear symmetry potential energy on the balance energy is *** is found that the balance energy of free neutrons is sensitive to the nuclear symmetry energy,while that of free protons is ***,the initial neutron/proton ratio dependence of the balance energy of free neutrons from Sn isotopes can be taken as a useful probe to constrain the stiffness of the nuclear symmetry energy.

关键词： symmetry energy directed flow balance energy

A TWO-GRID FINITE ELEMENT APPROXIMATION FOR NONliNEAR TIME FRACTIONAL TWO-TERM MIXED SUB-DIFFUSION AND DIFFUSION WAVE EQUATIONS

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Journal of Computational Mathematics 2022年第6期40卷 936-954页

作者： Yanping Chen Qiling Gu qingfeng li Yunqing Huang School of Mathematical Sciences South China Normal UniversityGuangzhou 510631China School of Mathematics and Computational Science Xiangtan UniversityXiangtan 411199China

In this paper,we develop a two-grid method(TGM)based on the FEM for 2D nonlinear time fractional two-term mixed sub-diffusion and diffusion wave equations.A two-grid algorithm is proposed for solving the nonlinear system,which consists of two steps:a nonlinear FE system is solved on a coarse grid,then the linearized FE system is solved on the fine grid by Newton iteration based on the coarse *** fully discrete numerical approximation is analyzed,where the Galerkin finite element method for the space derivatives and the finite difference scheme for the time Caputo derivative with orderα∈(1,2)andα1∈(0,1).Numerical stability and optimal error estimate O(h^(r+1)+H^(2r+2)+τ^(min{3−α,2−α1}))in L^(2)-norm are presented for two-grid scheme,where t,H and h are the time step size,coarse grid mesh size and fine grid mesh size,***,numerical experiments are provided to confirm our theoretical results and effectiveness of the proposed algorithm.

关键词： Two-grid method Finite element method Nonlinear time fractional mixed sub-diffusion and diffusion-wave equations L1-CN scheme Stability and convergence

An investigation of ab initio shell-model interactions derived by no-core shell model

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Science China(Physics,Mechanics & Astronomy) 2016年第9期59卷 52-58页

作者： XiaoBao Wang GuoXiang Dong qingfeng li CaiWan Shen ShaoYing Yu School of Science Huzhou University

The microscopic shell-model effective interactions are mainly based on the many-body perturbation theory （MBPT）, the first work of which can be traced to Brown and Kuo＇s first attempt in 1966, derived from the Hamada-Johnstou nucleon-nucleon potential. However, the convergence of the MBPT is still unclear. On the other hand, ab initio theories, such as Green＇s function Monte Carlo （GFMC）, no-core shell model （NCSM）, and coupled-cluster theory with single and double excitations （CCSD）, have made many progress in recent years. However, due to the increasing demanding of computing resources, these ab initio applications are usually limited to nuclei with mass up to A = 16. Recently, people have realized the ab initio construction of valence-space effective interactions, which is obtained through a second-time renormalization, or to be more exactly, projecting the full-many- body Hamiltonian into core, one-body, and two-body cluster parts. In this paper, we present the investigation of such ab initio shell-model interactions, by the recent derived sd-shell effective interactions based on effective J-matrix Inverse Scattering Potential （JISP） and chiral effective-field theory （EFT） through NCSM. In this work, we have seen the similarity between the ab initio shell- model interactions and the interactions obtained by MBPT or by empirical fitting. Without the inclusion of three-body （3-bd） force, the ab initio shell-model interactions still share similar defects with the microscopic interactions by MBPT, i.e., T = 1 channel is more attractive while T = 0 channel is more repulsive than empirical interactions. The progress to include more many-body correlations and 3-bd force is still badly needed, to see whether such efforts of ab initio shell-model interactions can reach similar precision as the interactions fitted to experimental data.

关键词： shell model effective interactions ab initio methods

Effects of a phase transition on two-pion interferometry in heavy ion collisions at √SNN=2.4-7.7 GeV

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Science China(Physics,Mechanics & Astronomy) 2023年第3期66卷 88-97页

作者： Pengcheng li Jan Steinheimer Tom Reichert Apiwit Kittiratpattana Marcus Bleicher qingfeng li Institut fur Theoretische Physik Johann Wolfgang Goethe Universitat FrankfurtFrankfurt am Main 60438Germany School of Science Huzhou UniversityHuzhou 313000China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China Frankfurt Institute for Advanced Studies Frankfurt am Main 60438Germany GSI Helmholtzzentrum f¨urSchwerionenforschung GmbH Darmstadt 64291Germany Helmholtz Research Academy Hesse for FAIR(HFHF) GSI Helmholtz Center for Heavy Ion PhysicsCampus FrankfurtFrankfurt am Main 60438Germany Center of Excellence in High Energy Physics&Astrophysics School of PhysicsSuranaree University of TechnologyNakhon Ratchasima 30000Thailand

Hanbury-Brown-Twiss(HBT) correlations for charged pions in central Au+Au collisions at √SNN=2.4-7.7 GeV(corresponding to beam kinetic energies in the fixed target frame from Elab=1.23 to 30 GeV/nucleon) are calculated using the ultra-relativistic quantum molecular dynamics model with different equations of state(EoSs).The effects of a phase transition at high baryon densities are clearly observed in the explored HBT *** results show that the available data on the HBT radii,RO/RSand R^(2)_(O)-R^(2)_(S),in the investigated energy region favor a relatively stiff EoS at low beam energies,which then turns into a soft EoS at high collision energies consistent with astrophysical constraints on the high-density EoS of quantum chromodynamics(QCD).The specific effects of two different phase transition scenarios on RO/RSand R^(2)_(O)-R^(2)_(S)are investigated.A phase transition with a significant softening of the EoS below four times the nuclear saturation density can be excluded using HBT *** results highlight that the pion’s RO/RSand R^(2)_(O)-R^(2)_(S)are sensitive to the stiffness of the EoS and can be used to constrain and understand the QCD EoS in a high baryon density region.

关键词： heavy ion collisions HBT correlation equation of state

Rhinoplasty in China: A review of the most important events in its history of development

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Chinese Journal of Plastic and Reconstructive Surgery 2022年第4期4卷 149-153页

作者： Shengli li qingfeng li Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai200011China

A review of the literature in commonly used retrieval systems generally yields minimal or no pertinent information on the early works of Chinese ***,the early works in rhinoplasty by pioneers *** Hu(胡懋廉)and *** Nyi(倪葆春)were retrieved from the database of Chinese Medical Journal published before1949 that overseas doctors could not gain access to online possibly due to the language barrier in collecting and processing those old professional data by main retrieval *** published original articles on costal cartilage applications for correction of saddle noses in as early as 1939 and 1949,respectively,which represent the earliest attempts of treating nasal deformities with costal cartilages in China as well as in *** private cosmetic surgical practices in rhinoplasty from the 1930s to the 1940s were recovered and briefly reviewed,and some of the most important clinical cases were *** important events related to rhinoplasty,such as the establishment of the first national society of rhinoplasty in Chengdu,China in 2011 and the successful performance of the first national congress on rhinoplasty in Shanghai,China in 2012,were included.

关键词： Rhinoplasty History Costal cartilage Society Congress

PRESSURE COMPENSATION METHOD OF UNDERWATER HYDRAUliC SYSTEM WITH HYDRAUliC POWER UNIT BEING UNDER ATMOSPHERIC CIRCUMSTANCE AND PRESSURE COMPENSATED VALVE

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Chinese Journal of Mechanical Engineering 2005年第3期18卷 419-423页

作者： Wang qingfeng li Yanmin Zhong Tianyu Xu Guohua State Key Laboratory of Fluid Power Transmission and Control Zhejiang University Hangzhou 310027 China

Based on the analysis of the-state-of-the-art of pressure compensation of underwater hydraulic systems （UHSs）, a new method of pressure compensation of UHSs, whose hydraulic power unit is in the atmospheric circumstance, is proposed. And a pilot-operated relief valve with pressure compensation is realized. The pressure compensation precision is guaranteed by direct detection. Its dynamic performance and stability are improved by a dynamic feedback. Theoretical study, simulation and experiment show that the pilot-operated relief valve with pressure compensation has a fine property of tracking underwater ambient pressure and meet the requirement of underwater ambient pressure compensation.

关键词： Underwater hydraulic system (UHS) Pressure compensation Underwater ambient pressure (UAP) Pressure relief valve