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Association between childhood obesity and gut microbiota:16S rRNA gene sequencing-based cohort study

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World Journal of Gastroenterology 2024年第16期30卷 2249-2257页

作者： Xu-Ming Li qing lv Ya-Jun Chen Lu-Biao Yan Xin Xiong Laboratory Department Nanjing Medical University Affiliated Obstetrics and Gynecology Hospital(Nanjing Maternal and Child Health Hospital)Nanjing 210004Jiangsu ProvinceChina Department of Pediatrics Shenzhen University General HospitalShenzhen 518055Guangdong ProvinceChina Department of Inspection Division Women’s Hospital of Nanjing Medical University(Nanjing Maternity and Child Health Care Hospital)Nanjing 210004Jiangsu ProvinceChina Department of Pediatrics Women’s Hospital of Nanjing Medical University(Nanjing Maternity and Child Health Care Hospital)Nanjing 210004Jiangsu ProvinceChina Department of Neonatology Chenzhou First People’s HospitalChenzhou 423000Hunan ProvinceChina

BACKGROUND This study aimed to identify characteristic gut genera in obese and normal-weight children(8-12 years old)using 16S rDNA *** research aimed to provide insights for mechanistic studies and prevention strategies for childhood *** normal-weight and thirty age-and sex-matched obese children were *** and body measurements were collected,and fecal samples underwent 16S rDNA *** differences in body mass index(BMI)and body-fat percentage were observed between the *** of gut microbiota diversity revealed lowerα-diversity in obese *** in gut microbiota composition were found between the two *** and Firmicutes were more abundant in the obese group,while Bacteroides and Sanguibacteroides were more prevalent in the control *** To identify the characteristic gut genera in obese and normal-weight children(8-12-year-old)using 16S rDNA sequencing,and provide a basis for subsequent mechanistic studies and prevention strategies for childhood *** Thirty each normal-weight,1:1 matched for age and sex,and obese children,with an obese status from 2020 to 2022,were included in the control and obese groups,*** information was collected through questionnaires and body measurements were obtained from both obese and normal-weight *** samples were collected from both groups and subjected to 16S rDNA sequencing using an Illumina MiSeq sequencing platform for gut microbiota diversity *** Significant differences in BMI and body-fat percentage were observed between the two *** Ace and Chao1 indices were significantly lower in the obese group than those in the control group,whereas differences were not significant in the Shannon and Simpson ***-Wallis tests indicated significant differences in unweighted and weighted UniFrac distances between the gut microbiota of normal-weight and obese children(P<0.01),suggest

关键词： Childhood obesity Gut microbiota 16S rDNA sequencing Diversity analysis Genus identification Body mass index

Recovering from prolonged cardiac arrest induced by electric shock:A case report

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World Journal of Clinical Cases 2024年第13期12卷 2248-2253页

作者： Jian Zhang Yan-Ru Qiao Ya-Dong Yang Guo-Zheng Pan Chong-qing lv Department of General Surgery Shengli Oilfield Central HospitalDongying 257000Shandong ProvinceChina Department of Emergency Medicine Shengli Oilfield Central HospitalDongying 257000Shandong ProvinceChina

BACKGROUND Cardiac arrest(CA)induced by electric shock is a rare occurrence,particularly in cases of prolonged ***,there is limited literature on similar incidents,and we present a relevant case *** SUMMARY A 27-year-old Asian male man,experiencing respiratory CA due to electric shock,was successfully restored to sinus rhythm after 50 min of cardiopulmonary resuscitation and 8 electrical defibrillation *** the subsequent stages,the patient received multiple organ function protection measures,leading to a successful recovery and eventual discharge from the *** Prolonging resuscitation time can enhance the chances of survival for patients,this study provide valuable insights into the management of electric shock-induced CA.

关键词： Electric shock Cardiac arrest Prolonged cardiopulmonary resuscitation Cerebral resuscitation Case report

省级政府推动“双师型”教师队伍建设政策扩散机理

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中国职业技术教育 2024年第18期 57-67页

作者：吕清康悦河北师范大学职业技术学院河北师范大学

基于政策扩散理论,采用文本分析法,从时间、空间、机制三个维度深入剖析省级政府在“双师型”教师队伍建设方面的政策扩散机制,发现在时间维度上,“双师型”教师队伍建设政策的扩散曲线呈现S型分布,其扩散过程可以分为三个阶段:政策扩... 详细信息

基于政策扩散理论,采用文本分析法,从时间、空间、机制三个维度深入剖析省级政府在“双师型”教师队伍建设方面的政策扩散机制,发现在时间维度上,“双师型”教师队伍建设政策的扩散曲线呈现S型分布,其扩散过程可以分为三个阶段:政策扩散的起步阶段(2016—2019年)、政策扩散的发展阶段(2020—2021年)和政策扩散的成熟阶段(2022年至今);在空间维度上,双师型教师队伍建设政策遵循空间扩散逻辑,形成了纵向的层级扩散、横向的区域扩散和平行部门的协同扩散;在机制维度上,“双师型”教师队伍建设受到学习、模仿、竞争和强制等四种机制的共同驱动,有效推动了“双师型”教师队伍建设的政策扩散。

关键词：职业教育 “双师型”教师政策扩散

教育家精神融入职业教育教师培养的内涵、价值与策略

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职业技术教育 2024年第10期45卷 12-17页

作者：吕清杨贺凯河北师范大学职业技术学院石家庄050024

教育家精神在当代具有十分丰富的内涵,对职业教育教师培养提出了新要求,主要包括职业教育教师应具有心有大我、至诚报国的理想信念,言为士则、行为世范的道德情操,启智润心、因材施教的育人智慧,勤学笃行、求是创新的躬耕态度,乐教爱生... 详细信息

教育家精神在当代具有十分丰富的内涵,对职业教育教师培养提出了新要求,主要包括职业教育教师应具有心有大我、至诚报国的理想信念,言为士则、行为世范的道德情操,启智润心、因材施教的育人智慧,勤学笃行、求是创新的躬耕态度,乐教爱生、甘于奉献的仁爱之心,胸怀天下、以文化人的弘道追求。教育家精神融入职业教育教师培养的价值是:与“工匠之师”教育情感的共生发展,促进职业教育教师的“知行合一”,全面提升职业教育教师的知识创新能力等。教育家精神融入职业教育教师培养的具体策略是:转换目标,实现从精神象征到真正推动人才培养;持续激发动力,实现从认知认同到情感认同再到行为认同的螺旋上升;关注学生能力培养,实现职业教育教师素质的全面提升;丰富培养载体,实现从学校“一元”主导到“多元”协同。

关键词：教育家精神职业教育教师工匠之师

附设间隙阻尼减震装置的高位隔震连体结构振动台试验研究

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建筑结构学报 2024年第4期45卷 12-23页

作者：律清卢文胜傅博熊洋钱玮宁波工程学院建筑与交通工程学院浙江宁波315211 中国地震局工程地震工程与工程振动重点实验室黑龙江哈尔滨150080 地震灾害防治应急管理部重点实验室黑龙江哈尔滨150080 同济大学土木工程防灾减灾全国重点实验室上海200092 长安大学建筑工程学院陕西西安710061 山东建筑大学建筑结构加固改造与地下空间工程教育部重点实验室山东济南250101 宁夏大学土木与水利工程学院宁夏银川750021

针对高位隔震连体结构,提出附设间隙阻尼装置控制罕遇地震下连廊隔震支座位移。通过设计高宽比为6的双塔连体结构试验模型,对连廊与塔楼顶部仅采用隔震连接以及隔震与间隙阻尼装置连接的两类结构体系进行模拟地震振动台试验研究。选取远... 详细信息

针对高位隔震连体结构,提出附设间隙阻尼装置控制罕遇地震下连廊隔震支座位移。通过设计高宽比为6的双塔连体结构试验模型,对连廊与塔楼顶部仅采用隔震连接以及隔震与间隙阻尼装置连接的两类结构体系进行模拟地震振动台试验研究。选取远场El Centro波和速度脉冲效应明显的近场Chi-Chi波、Kobe波作为地震激励。通过测量隔震支座水平位移、间隙阻尼装置力与位移响应、连廊结构加速度响应以及塔楼结构加速度和位移响应,分析罕遇地震与极罕遇地震作用下间隙阻尼装置对隔震支座位移的控制效果,以及对连廊结构和下部塔楼结构抗震性能的影响。结果表明:间隙阻尼装置可以有效地控制罕遇和极罕遇地震作用下隔震支座位移,8度罕遇地震作用下,隔震支座最大位移减小59.61%;间隙阻尼装置传导轴与限位环产生剧烈冲击,引起高频振动能量进入连廊结构,导致连廊水平向加速度响应有所放大,而竖向加速度响应显著;远场地震作用下,间隙阻尼装置的启动对塔楼结构楼层加速度和层间位移角有所放大,但未造成不利影响;在速度脉冲周期与整体结构基本自振周期接近的近场地震作用下,当地震波峰值加速度为0.40g时,附设间隙阻尼装置使塔楼结构楼层峰值加速度和峰值层间位移角分别减小24.09%和31.7%,对塔楼结构具有一定减震控制作用。

关键词：连体结构高位隔震间隙阻尼装置振动台试验抗震性能

我国职业教育评价研究现状与展望——基于CiteSpace知识图谱的可视化分析

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齐齐哈尔高等师范专科学校学报 2024年第3期 1-5页

作者：吕清杨贺凯河北师范大学职业技术学院石家庄050024

职业教育评价是推动职业教育高质量发展的关键。本研究利用CiteSpace软件对357篇有关职业教育评价的相关研究进行了可视化分析,发现当前相关研究主要聚焦于评价体系、标准、指标、主体、方式、方法、国际比较、改革与创新、现存问题等方... 详细信息

职业教育评价是推动职业教育高质量发展的关键。本研究利用CiteSpace软件对357篇有关职业教育评价的相关研究进行了可视化分析,发现当前相关研究主要聚焦于评价体系、标准、指标、主体、方式、方法、国际比较、改革与创新、现存问题等方面,但也存在研究者分布不均和合作网络密度低等问题。因此,未来职业教育评价研究应注重改革评价标准、强化研究合作、开阔国际视野、善用现代信息技术进行评价。

关键词：职业教育评价 CiteSpace 职业教育知识图谱可视化分析

Experimental observation of Fermi-level flat band in novel kagome metal CeNi_(5)

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Chinese Physics B 2024年第8期33卷 467-472页

作者：陈学智王乐张帅张任杰程以伟胡裕栋孟承诺刘正太吕佰晴黄耀波 Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghai 200240China University of Chinese Academy of Sciences Beijing 100049China Shenzhen Institute for Quantum Science and Engineering Southern University of Science and TechnologyShenzhen 518055China International Quantum Academy Shenzhen 518048China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Beijing National Laboratory for Condensed Matter Physics and Institute of Physics Chinese Academy of SciencesBeijing 100190China School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Zhangjiang Institute for Advanced Study Shanghai Jiao Tong UniversityShanghai 200240China Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China

Kagome materials are a class of material with a lattice structure composed of corner-sharing triangles that produce various exotic electronic phenomena,such as Dirac fermions,van Hove singularities,and flat ***,most of the known kagome materials have a flat band detached from the Fermi energy,which limits the investigation of the emergent flat band *** this work,by combining soft x-ray angle-resolved photoemission spectroscopy(ARPES)and the first-principles calculations,the electronic structure is investigated of a novel kagome metal CeNi_(5) with a clear dispersion along the kz direction and a Fermi level flat band in theΓ–K–M–Γ***,resonant ARPES experimental results indicate that the valence state of Ce ions is close to 4^(+),which is consistent with the transport measurement *** results demonstrate the unique electronic properties of CeNi_(5) as a new kagome metal and provide an ideal platform for exploring the flat band physics and the interactions between different types of flat bands by tuning the valence state of Ce ions.

关键词： ARPES kagome lattice band structure flat band

块石破碎性质对土石混合体剪切带厚度的影响研究

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工程地质学报 2024年第1期32卷 39-51页

作者：胡峰祝诗逸王颂朱益军吕庆李志清浙江数智交院科技股份有限公司杭州310030 浙江大学建筑工程学院杭州310058 中国科学院地质与地球物理研究所页岩气与地质工程重点实验室北京100029

土石混合体作为一种典型的浅表层堆积体,常引发不同规模的滑坡灾害。本文通过对比土石混合体在室内大型直剪和离散元(PFC2D)数值模拟直剪条件下剪切带厚度随含石量和上覆压力的变化特征,以期进一步揭示影响土石混合体剪切带厚度的主要... 详细信息

土石混合体作为一种典型的浅表层堆积体,常引发不同规模的滑坡灾害。本文通过对比土石混合体在室内大型直剪和离散元(PFC2D)数值模拟直剪条件下剪切带厚度随含石量和上覆压力的变化特征,以期进一步揭示影响土石混合体剪切带厚度的主要控制因素。试验结果显示,室内试验中土石混合体的剪切带厚度主要受含石量的影响,其次为上覆压力,受块石尺寸的影响不明显。剪切带厚度随含石量从0增加到50%时表现为增大的趋势,随含石量的继续增大而表现为减小的趋势。但上覆应力小于200 kPa时,剪切带厚度随上覆应力的增大表现为增大的趋势,但上覆应力超过200 kPa时,其值表现为减小的趋势。然而,在数值模拟计算中,考虑块石不可破碎的情况下剪切带裂纹区域的宽度随含石量和上覆压力的增大表现为持续增大的趋势特征。分析认为,土石混合体剪切中大块石之间咬合后的齿轮带动效应是促使剪切带厚度增大的重要原因,而骨架结构含石量以及高垂直应力下块石咬合部位因高度的应力集中,随后导致的咬合棱角破碎,块石变形被限制在一定的区域内,却抑制了剪切带厚度的进一步增大。相反,在块石不可破碎的数值模拟计算中,高含石量试样内块石可持续的咬合滚动,促使周围的块石也发生变形,进而增大了剪切带的厚度。研究结果有利于揭示土石混合体的剪切变形破坏机制。

关键词：土石混合体剪切带厚度含石量大型直剪 PFC2D

A new estimation method and an anisotropy index for the deformation modulus of jointed rock masses

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Journal of Rock Mechanics and Geotechnical Engineering 2022年第1期14卷 153-168页

作者： Bohu Zhang Junyan Mu Jun Zheng qing lv Jianhui Deng State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu610500China School of Geoscience and Technology Southwest Petroleum UniversityChengdu610500China Department of Civil Engineering Zhejiang UniversityHangzhou310058China Center for Balance Architecture Zhejiang UniversityHangzhou310007China State Key Laboratory of Hydraulics and Mountain River Engineering College of Water Resource and HydropowerSichuan UniversityChengdu610065China

The deformation modulus of a rock mass is an important parameter to describe its mechanical *** this study,an analytical method is developed to determine the deformation modulus of jointed rock masses,which considers the mechanical properties of intact rocks and joints based on the superposition *** to incorporating the variations in the orientations and sizes of joint sets,the proposed method is applicable to the rock mass with persistent and parallel joints as well as that with nonpersistent and nonparallel *** addition,an anisotropy index AIdmfor the deformation modulus is defined to quantitatively describe the anisotropy of rock *** range of AIdmis from 0 to 1,and the more anisotropic the rock mass is,the larger the value of AIdmwill *** evaluate the proposed method,20 groups of numerical experiments are conducted with the universal distinct element code(UDEC).For each experimental group,the deformation modulus in 24 directions are obtained by UDEC(numerical value)and the proposed method(predicted value),and then the mean error rates are *** that the mean error rate is the mean value of the error rates of the deformation modulus in 24 directions,where for each direction,the error rate is equal to the ratio of numerical value minus predicted value to the numerical *** results show that(i)for different experimental groups,the mean error rates vary between 5.06%and 22.03%;(ii)the error rates for the discrete fracture networks(DFNs)with two sets of joints are at the same level as those with one set of joints;and(iii)therefore,the proposed method for estimating the deformation modulus of jointed rock masses is valid.

关键词： Deformation modulus Analytical method Anisotropy index Jointed rock masses Mechanical behavior Discrete fracture network(DFN)