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Large Disparity between Prevalence and Treatment Rates for hepatitis C in Western China

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Journal of Clinical and Translational hepatology 2018年第4期6卷 385-390页

作者： Zhi-Wei Chen Zhao Li qiao-he wang Xiao-Ling Wu Hu Li Hong Ren Peng Hu Department of Infectious Diseases Institute for Viral HepatitisThe Key Laboratory of Molecular Biology for Infectious DiseasesChinese Ministry of EducationThe Second Affiliated Hospital of Chongqing Medical UniversityChongqingChina

Background and Aims:Recently,the World health Organization adopted the first-ever global hepatitis strategy with the dream of eliminating viral hepatitis as a public health threat by ***,the epidemiology and treatment rates of hepatitis C virus(HCV)infection in Western China are still ***:A total of 111,916 adult individuals(15-96 years)who underwent the HCV-antibody(HCV-Ab)test in the Second Affiliated Hospital of Chongqing Medical University between 2013 and 2015 were included in this *** retrospectively analyzed the electronic medical records'data for each,and the positivity of HCV-Ab and the treatment of HCV RNA-positive patients were ***:During 2013-2015,the crude prevalence of HCVAb was 1.4%(95%CI:1.4-1.5;1,611/111,916)and the adjusted prevalence of HCV-Ab was 1.7%(95%CI:1.6-1.8),which was higher than in the 2006 national study(0.43%).The prevalence was 2-times higher in males than females(2.0%vs.1.1%,phe HCV RNA-positive patients received standard peginterferon plus ribavirin treatment,with 370(82%)that completed treatment,of whom 272(74%)achieved sustained virologic response(SVR).Particularly,11%(32/292)of HCV RNA-positive patients were HBsAg-positive,and the SVR rate for them was lower than for the HBsAg-negative patients,but no significant difference was ***:HCV infection may have increased since 2006 in Western *** SVR rate of peg-interferon plus ribavirin treatment was high,but the proportion of untreated HCV patients was ***,more efforts need to be made by the government to create a scientific-based policy for HCV treatment and prevention.

关键词： Epidemiology hepatitis C virus Hospital-based population study Treatment

An Enhanced Dual-Layer Ensemble Framework for Porosity Prediction Utilizing Conventional Well Logging Data

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Journal of Earth Science 2025年

作者： Lu qiao Shengyu Yang Qinhong Hu Huijun wang Taohua he National Key Laboratory of Deep Oil and Gas， China University of Petroleum (East China) Laboratory for Marine Mineral Resources， Qingdao National Laboratory for Marine Science and Technology Hubei Key Laboratory of Petroleum Geochemistry and Environment (Yangtze University)， Yangtze University

Porosity is the one of the most fundamental and critical parameters for reservoir characterization and is closely related to the hydrocarbon storage capacity. The interpretation methods of conventional well logs have poor generalization capabilities to achieve the desired accuracy in porosity prediction. The increasing adoption of machine learning has ameliorated this predicament to some extent， but it remains difficult to reconstruct the complex and nonlinear relationship between logging responses and porosity by relying on individual machine learning models alone. This work proposes a two-layer model ensemble framework to predicte porosity， which includes base regressors in the first layer and meta regressor in the second layer. The results indicate that the Light Gradient Boosting Machine (LightGBM) - Categorical-Features Gradient Boosting (CatBoost) ensemble model provides the highest prediction accuracy for the given dataset and is applied for porosity evaluation at other logged depths. This work also points out that the base regressor should be accurate and complex， while the structure of the meta-regressor should be simple in order to achieve the desired performance. Furthermore， the proposed model ensemble framework is versatile and applicable to reservoir evaluation， engineering development， and other potential fields due to its effectiveness and convenience.

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中国上市企业套期保值对企业价值的影响

西安交通大学学报（社会科学版） 2017年第1期37卷 39-44页

作者：薛宏刚何乔王浩西安交通大学经济与金融学院陕西西安710061

使用面板数据分析方法,根据市场参与者使用衍生工具的不同特点,以中国化工行业及银行业上市公司为样本,对中国上市企业套期保值行为对企业价值的影响进行了实证检验。结果表明,同一经济周期内,套期保值行为对企业价值的影响存在行业差异... 详细信息

使用面板数据分析方法,根据市场参与者使用衍生工具的不同特点,以中国化工行业及银行业上市公司为样本,对中国上市企业套期保值行为对企业价值的影响进行了实证检验。结果表明,同一经济周期内,套期保值行为对企业价值的影响存在行业差异,化工企业使用衍生工具并没有提高企业价值,银行业的套期保值行为对银行权益资本有更多的价值提升,而对银行资产收益率没有显著影响。

关键词：套期保值衍生工具企业价值总资产收益率托宾Q

Plasmonic tandem heterojunctions enable high-efficiency charge transfer for broad spectrum photocatalytic hydrogen production

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Journal of Energy Chemistry 2025年第1期100卷 710-720页

作者： Wenxuan Chen Xiu-Qing qiao Guo Hui Bojing Sun Dongfang Hou Meidi wang Xueqian Wu Tao Wu Dong-Sheng Li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University Hubei Three Gorges Laboratory College of Chemistry and Materials Science and Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry Jinan University

Rational engineering of semiconductor photocatalysts for efficient hydrogen production is of great significance but still challenging,primarily due to the limitations in charge transfer ***,a fascinating plasmonic tandem heterojunction with the hc-CdS/Mo2C@C heterostructure is aimfully prepared for effectively promoting the charge separation kinetics of the CdS photocatalyst via the synergistic strategy of phase junction,Schottky junction,and photothermal *** difference in atomic configuration between cubic-CdS （c-CdS） and hexagonal-CdS （h-CdS） leads to effective charge separation through a typical Ⅱ charge transfer mechanism,and plasmonic Schottky junction further extracts the electrons in the hc-CdS phase junction to realize gradient charge ***,the photothermal effect of Mo2C@C helps to expand the light absorption,accelerate charge transfer kinetics,and reduce the hydrogen evolution energy *** carbon layer provides a fast channel for charge transfer and protects the photocatalyst from *** a result,the optimized hc-CMC photocatalyst exhibits a significantly high photocatalytic H2production activity of 28.63 mmol/g/h and apparent quantum efficiency of 61.8%,surpassing most of the reported *** study provides a feasible strategy to enhance the charge transfer kinetics and photocatalytic activity of CdS by constructing plasmonic tandem heterogeneous junctions.

关键词： Cadmium sulfide

Imidazolium-based ionic polymers for fast and efficient anion-exchange driven capture of Cr2O72-

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Science China Chemistry 2025年

作者： Yishou wang Xiaonan Yuan Xingxing Gou Xiatian Song Xiaogang wang Ling Guo Yanfeng Liu Chengfang qiao Chunsheng Zhou Yingfeng Han Shaanxi Key Laboratory of Comprehensive Utilization of Tailings Resources Shaanxi Engineering Research Center for Mineral Resources Clean & Efficient Conversion and New Materials College of Chemical Engineering and Modern Materials Shangluo University Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education Xi'an Key Laboratory of Functional Supramolecular Structure and Materials College of Chemistry and Materials Science Northwest University

The pervasive issue of chromium（VI） contamination,particularly in dichromate (Cr2O2-7),resulting from unchecked industrial growth and inadequate waste management,remains a pressing concern that demands immediate and dedicated ***,we present two novel imidazolium-based ionic polymers （ImIPs）.The ImIPs boast a highly cationic structure rich in bromide（Br-） ions and exhibit remarkable porosity,facilitating the easy exchange of these ions for chromate (Cr2O2-7) through anion *** unique combination leads to exceptional performance,including a high adsorption capacity （423 mg/g）,rapid adsorption rate (75 mg g-1min-1),and a broad operational pH range （2–12）.Moreover,our material demonstrates remarkable reusability,maintaining its efficacy even after 10 cycles without significant loss of *** mechanistic studies underscore the role of ion-exchange chemistry in effectively removing dichromate by the presented ImIPs,providing strong evidence for their suitability as a robust solution to address the ongoing challenges in water *** findings represent a crucial step in developing advanced materials for tackling chromium（VI） pollution.

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A dry-electrode enabled ECG-on-Chip with arrhythmia-aware data transmission

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Science China(Information Sciences) 2025年

作者： Xinzi XU Yanxing SUO Yang ZHAO Peiyi ZHOU Xiao HAN qiao CAI Min wang Jiajun YUAN Liebin ZHAO Yongfu LI Guoxing wang Yong LIAN Department of Micro-Nano Electronics and MoE Key Lab of Artificial Intelligence Shanghai Jiao Tong University Pediatric AI Clinical Application and Research Center Shanghai Engineering Research Center of Intelligence Pediatrics (SERCIP) Child Health Advocacy Institute Shanghai Children's Medical Center School of MedicineShanghai Jiao Tong University Shanghai Engineering Research Center of Intelligence Pediatrics (SERCIP) Xin Hua Hospital Affiliate to Shanghai Jiao Tong University School of Medicine

Early detection and treatment of cardiovascular diseases (CVDs) can be significantly enhanced through the use of flexible wearable electrocardiogram (ECG) sensors, potentially reducing CVD-related mortality. This paper introduces an ECG-on-Chip (EoC) solution tailored for flexible ECG sensors, incorporating novel features to address common challenges in wearable ECG technology. The EoC integrates a chopper-stabilized capacitively-coupled instrumentation amplifier (CS-CCIA),ensuring a high common-mode rejection ratio (CMRR) and low noise performance. Performance is further boosted via a positive feedback loop (PFL) and a programmable gain amplifier (PGA) with shared on-chip calibration logic, which enhances input impedance and minimizes gain variability to ensure consistent algorithm performance. Additionally, a secondary chopping technique is employed to further reduce noise, achieving an input-referred noise level of 454 nVrms. The embedded algorithm within the EoC is designed to extract clinically meaningful features, facilitating robust real-time arrhythmia analysis. Fabricated using a 0.18μm CMOS process, the EoC consumes 14.9μW with a supply voltage of 1.2 V. The algorithm’s efficacy has been validated over 0.4 million heartbeats, demonstrating a sensitivity of over 99.7%for R-peak detection and 98.3%for arrhythmia analysis. To demonstrate practical application, the EoC has been integrated with a commercial Bluetooth low energy (BLE)transceiver, forming a wireless arrhythmia monitoring sensor equipped with dry electrodes. This system consumes 292.04μW in arrhythmia-aware transmission mode, supporting 13 days of operation with a 30 mAh thin-film battery.

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党内法规视域下纪律建设的历史轨迹

学习论坛 2025年第1期 44-55页

作者：乔贵平王泽人天津师范大学政治与行政学院天津300387

严明的纪律是中国共产党在长期奋斗实践中铸造的组织品格。从党的建设历程来看,纪律建设从建党伊始就是明确的组织意识,也是党加强自身治理的重要内容。在百余年发展过程中,中国共产党从完善纪律法规、加强纪律教育、优化纪检机构、严... 详细信息

严明的纪律是中国共产党在长期奋斗实践中铸造的组织品格。从党的建设历程来看,纪律建设从建党伊始就是明确的组织意识,也是党加强自身治理的重要内容。在百余年发展过程中,中国共产党从完善纪律法规、加强纪律教育、优化纪检机构、严格纪律执行等方面不断延展与深化纪律建设,在遵循党章、依规治党、纪律治党中推进党的纪律建设。在新民主主义革命时期,中国共产党将纪律严明作为组织严密的坚强保障,奠定了革命胜利的基础;在社会主义革命和建设时期,为适应执政党的角色和国家治理的需要,党的纪律建设内容内核愈发清晰,“纪律与党的中心任务”“纪律与团结统一”的关系进一步凸显,彰显了纪律在维护党的团结统一和推进中心任务中的重要作用;在改革开放和社会主义现代化建设新时期,从严治党、严肃党纪成为党内治理的基本要求,党在反腐倡廉制度体系中突出纪律,纪律建设逐步制度化;中国特色社会主义进入新时代,党的纪律不仅成为维护党内秩序、规范党员行为的治本之策,也在全社会形成强大的纪律震慑力,推动党内法规与国家法律的有机衔接,确保党的纪律规矩严明,推动全面从严治党向纵深发展。

关键词：纪律建设党内法规从严治党纪律治党

Atomic-layer-deposited （ALD） Al2O3passivation dependent interface chemistry, band alignment and electrical properties of HfYO/Si gate stacks

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Journal of Materials Science & Technology 2019年第5期35卷 769-776页

作者： Shuang Liang Gang he Die wang Fen qiao School of Physics and Materials Science Radiation Detection Materials & Devices Lab Anhui UniversityHefei 230601 China Institute of Physical Science and Information Technology Anhui University Hefei 230601 China School of Energy & Power Engineering Jiangsu University Zhenjiang 212013 China

In this work, the effects of atomic-layer-deposited(ALD) Al2O3 passivation layers with different thicknesses on the interface chemistry and electrical properties of sputtering-derived HfYO gate dielectrics on Si substrates have been investigated. The results of electrical measurements and X-ray photoelectron sepectroscopy(XPS) showed that 1-nm-thick Al2O3 passivation layer is optimized to obtain excellent electrical and interfacial properties for HfYO/Si gate stack. Then, the metal-oxide-semiconductor capacitors with HfYO/1-nm Al2O3/Si/Al gate stack were fabricated and annealed at different temperatures in forming gas(95% N2+5% H2). Capacitance-voltage(C-V) and current density-voltage(J-V) characteristics showed that the 250℃-annealed HYO high-k gate dielectric thin film demonstrated the lowest border trapped oxide charge density(-3.3 × 1010 cm-2), smallest gate-leakage current(2.45 × 10-6 A/cm2 at 2 V)compared with other samples. Moreover, the annealing temperature dependent leakage current conduction mechanism for Al/HfYO/Al2O3/Si/Al MOS capacitor has been investigated systematically. Detailed electrical measurements reveal that Poole-Frenkle emission is the main dominant emission in the region of low and medium electric fields while direct tunneling is dominant conduction mechanism at high electric fields.

关键词： Al2O3passivation layer Co-sputtering HYO films Annealing Electrical properties Conduction mechanism

Male larval experience of cues from adult rivals alters lifetime sperm investment patterns in a sperm heteromorphic moth, Ephestia kuehniella

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Insect Science 2023年第6期30卷 1773-1783页

作者： Junyan Liu Xiong Zhao he qiao wang School of Agriculture and Environment Massey UniversityPalmerston NorthNew Zealand

Male animals may adjust their resource allocations for reproduction and other fitness functions in response to cues from rivals. For instance, adult males increase their investment in sperm for a higher paternity share when they perceive sperm competition risk in their surroundings. In nature, both juveniles and adults may coexist spatially and temporally. Yet, it is not clear how juvenile males of different ages respond to cues from adult rivals and fine-tune their lifetime investment in sperm production and ejaculation in any insect. here we used the Mediterranean flour moth, Ephestia kuehniella, which produces both fertile eupyrene and infertile apyrene sperm, to explore this question. We demonstrate that the late, but not early, instar larvae are sensitive to adult male cues. As a response, they produce more sperm before emergence and their resultant adults have shorter mating latency and ejaculate more sperm in the first few matings. When the juvenile stage produces more eupyrenes, the adult stops making these sperm, but regardless of the number of apyrenes produced during the juvenile stage, the adult continues to make them. These findings suggest that the number of spermatogonia for eupyrenes may be limited and that for apyrenes may be flexible. Our results show that the insect does not trade off survival, mating frequency, body size, or testis size for sperm production in response to adult males during the larval stage. Knowledge created in the present study offers insight into the stage-dependent sensitivity of juvenile males to cues from adult rivals and subsequent lifetime resource allocations.

关键词： immature stage Lepidoptera spermatogenesis sperm allocation sociosex-ual environment