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铜污酸中铼的分离提取研究进展

工程科学学报 2024年第3期46卷 397-406页

作者：乔晋玺郭学益李栋许志鹏王亲猛中南大学冶金与环境学院长沙410083

铼是一种战略性金属,在军工、航天及航空领域具有重要的地位,由于其独特的性质成为了航空航天发动机中不可或缺的材料.铼金属几乎没有独立矿床,其资源主要伴生于铜、钼等金属矿中.铜矿中铼资源经过铜冶炼工序后富集到废弃的污酸当中,从... 详细信息

铼是一种战略性金属,在军工、航天及航空领域具有重要的地位,由于其独特的性质成为了航空航天发动机中不可或缺的材料.铼金属几乎没有独立矿床,其资源主要伴生于铜、钼等金属矿中.铜矿中铼资源经过铜冶炼工序后富集到废弃的污酸当中,从污酸中回收铼成为铼冶金的重要研究内容.本文综述了污酸中铼提取的主要技术难点,对现有的分离提取方法进行了阐述及对比,主要包括化学沉淀法、溶剂萃取法、离子交换法、吸附法等,分析了各技术现阶段存在的问题,为污酸中铼的分离提取技术发展提供参考.最后展望未来,污酸中铼的分离提取应向绿色环保、短流程、高选择性的方向发展.

关键词：铼铜污酸分离提取溶剂萃取离子交换

Enhanced polysulfide redox kinetics by niobium oxynitrides via insitu adsorptive and catalytic effect in wide temperature range

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Nano Research 2022年第7期15卷 6200-6207页

作者： Benben Wei Chaoqun Shang qiao Cu Le Hu Xuelian Fu Guofu Zhou Xin Wang School of Materials Science and Engineering&Hubei Key Laboratory of Plasma Chemistry and Advanced Materials Wuhan Institute of TechnologyWuhan 430205China Faculty of Materials Science and Chemistry China University of GeosciencesWuhan 430074China Guangdong Provincial Key Laboratory of Optical Information Materials and Technology&South China Academy of Advanced Optoelectronics South China Normal UniversityGuangzhou 510006China School of Materials Science and Engineering&State Key Laboratory of Material Processing and Die and Mold Technology Huazhong University of Science and TechnologyWuhan 430074China

The development of Li-S batteries(LSBs)is hindered by the low utilization of S species and sluggish redox reaction *** metal oxides always possess high adsorption to polar S species,while conductive metal nitrides show fast electron transport and ensure fast redox reaction of S *** combination merits of metal oxides and metal nitrides in one provide an effective strategy to improve the electrochemical performance of *** this work,defect design of niobium oxynitrides highly dispersed on graphene(NbON-G)is evaluated as effective trapper and catalyst for S *** to the effective structural merits including enriched active sites,alleviated volume variation,defect modulated electronic property,and in-situ chemisorption and catalytic conversion of soluble lithium polysulfides(LiPSs),the LSBs with NbON-G modified separator show remarkably enhanced performance compared to NbN-G and Nb_(2)O_(5)-***,even at low temperature of−40°C,the LSBs with NbON-G can operate for 1,000 cycles with 0.04%capacity decay per cycle(Rate:2 C).

关键词： lithium polysulfides Li-S batteries niobium oxynitrides catalyst low temperature

PI3K/Akt/mTOR Signaling as Targets for Developing Anticancer Agents from Marine Organisms

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Journal of Ocean University of China 2021年第3期20卷 688-694页

作者： GUO Mingyue ZUO Ling qiao Gan LIU Minghua CAO Shousong LIN Xiukun Department of Pharmacology School of PharmacySouthwest Medical UniversityLuzhou 646000China Central Nervous System Drug Key Laboratory of Sichuan Province Luzhou 646000China

The PI3K/Akt/mTOR signaling pathway is one of the most frequently dysregulated pathways in *** the PI3K-mediated pathway has been an important strategy for developing novel anticancer *** the past decades,more than 40 inhibitors of the PI3K/Akt/mTOR pathway have been developed at different clinical ***,everolimus,idelalisib,and copanlisib have been approved for clinical use by the Food and Drug Administration of the United States(FDA).However,the toxic-ity and drug resistance limit their efficiency in the *** compounds with greater potency and selectivity,as well as im-proved therapeutic indices with reduced toxicity,are clearly *** the past three decades,a lot of bioactive ingredients with anticancer effects by affecting the PI3K-mediated pathways have been found from marine *** the present mini-review,anticancer compounds from marine source that target the PI3K/Akt/mTOR signaling were *** molecular entities and their modes of action were *** marine compounds targeting special factors of the PI3K/Akt/mTOR were highlighted.

关键词： marine organisms PI3K/Akt/mTOR pathway anticancer activity

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次氯酸盐氧化剂同时脱硫脱硝一体化

化工进展 2024年第9期43卷 5282-5289页

作者：李一梁李斯张立兴乔江鱼崔忠宜陈进徐强赵晨西安建筑科技大学冶金工程学院陕西西安710055

为了实现冶炼烟气的有效脱硫脱硝,采用两种次氯酸盐——NaClO和Ca(ClO)_(2)在串联式鼓泡反应器中对模拟冶炼烟气进行了同时去除NO和SO_(2)的对比性实验。考察了两种氧化剂的浓度、反应器个数、反应温度以及溶液的p H等参数对同时去除NO... 详细信息

为了实现冶炼烟气的有效脱硫脱硝,采用两种次氯酸盐——NaClO和Ca(ClO)_(2)在串联式鼓泡反应器中对模拟冶炼烟气进行了同时去除NO和SO_(2)的对比性实验。考察了两种氧化剂的浓度、反应器个数、反应温度以及溶液的p H等参数对同时去除NO和SO_(2)效率的影响。结果表明,当使用次氯酸盐氧化剂时,SO_(2)均稳定在较好的去除范围内,NO的去除效率随着氧化剂浓度的升高和反应器个数的增加而提高,随着反应温度的升高和溶液p H的增大而减小。两种氧化剂的对比实验表明,相较于Na Cl O来说,Ca(Cl O)_(2)具有更好的脱硫脱硝效率。在最佳反应条件下,即Ca(Cl O)_(2)浓度为25mmol/L、反应器个数为3、反应温度为25℃、溶液p H为6时,有最佳的同时脱硫脱硝效率,分别为95.4%和88%。此外,还提出了次氯酸盐吸收剂同时脱硫脱硝的反应机理,NO与次氯酸盐氧化剂进行接触反应生成NO_(2)-和NO_(3)^(-),SO_(2)则与之反应生成SO_(4)^(2-),在与Ca(Cl O)_(2)反应时会生成部分Ca SO_(4)沉淀,NO和SO_(2)在此过程中得以去除。

关键词：次氯酸钠次氯酸钙脱硫脱硝冶炼烟气鼓泡反应器

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Genome-wide identification, classification, and expression profiling of serine esterases and other esterase-related proteins in the tobacco hornworm, Manduca sexta

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Insect Science 2023年第2期30卷 338-350页

作者： Zelong Miao Chao Xiong Xiaolong Cao Tisheng Shan qiao Jin Haobo Jiang Department of Entomology and Plant Pathology Oklahoma State UniversityOklahomaStillwaterUSA

Serine esterases(SEs)are hydrolases that catalyze the conversion of carboxylic esters into acids and *** and carboxylesterases constitute two major groups of *** over a hundred of insect genomes are known,systematic identification and classification of SEs are rarely performed,likely due to large size and complex composition of the gene family in each *** their key roles in lipid metabolism and other physiological processes,we have categorized 144 *** SEs and SE homologs(SEHs),114 of which contain a motif of *** sequence alignment and phylogenetic tree analysis have revealed 39 neutral lipases(NLs),3 neutral lipase homologs(NLHs),11 acidic lipases(ALs),3 acidic lipase homologs(ALHs),a lipase-3,a triglyceride lipase,a monoglyceride lipase,a hormone-sensitive lipase,and a GDSL ***-three carboxylesterase genes encode 29α-esterases(AEs),12 AEHs(e.g.,SEH4-1–3),20 feruloyl esterases(FEs),2 FEHs,2β-esterases(BEs),2 integument esterases(IEs),1 IEH,4 juvenile hormone esterases,2 acetylcholinesterases,gliotactin,6 neuroligins,neurotactin,and an uncharacteristic esterase *** addition to these GXSXG proteins,we have identified 26 phospholipases and 13 *** profiling of these genes in specific tissues and stages has provided insights into their functions including digestion,detoxification,hormone processing,neurotransmission,reproduction,and developmental *** summary,we have established a framework of information on SEs and related proteins in *** to stimulate their research in the model species and comparative investigations in agricultural pests or disease vectors.

关键词： carboxylesterase esterase lipase phospholipase phylogenetic analysis RNA-Seq thioesterase

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胶结面缺陷对堆石混凝土抗压强度影响

贵州大学学报（自然科学版） 2024年第3期41卷 94-101页

作者：刘云柯乔浩洋赵应洪杨韬贵州大学土木工程学院贵州贵阳550025

堆石混凝土(rock-filled concrete, RFC)独特的施工技术导致其缺陷与传统混凝土不一样。通过物理试验与真实破坏过程分析(realistic failure process analysis, RFPA)数值模拟探讨了堆石混凝土中堆石与自密实混凝土(self-compacting con... 详细信息

堆石混凝土(rock-filled concrete, RFC)独特的施工技术导致其缺陷与传统混凝土不一样。通过物理试验与真实破坏过程分析(realistic failure process analysis, RFPA)数值模拟探讨了堆石混凝土中堆石与自密实混凝土(self-compacting concrete, SCC)胶结面缺陷及自密实缺陷对其抗压性能的影响。结果表明:随着缺陷数量的增加,堆石混凝土的无侧限抗压强度下降。同等缺陷数量下,胶结面缺陷试件的抗压强度低于自密实缺陷试件。同时,声发射分析显示,胶结面缺陷试件破坏所需能量更低,表明胶结面缺陷对材料力学性能有更为显著的负面影响。这些发现为理解和改善堆石混凝土结构设计与耐久性提供了重要参考。

关键词：堆石混凝土胶结面缺陷自密实缺陷抗压强度

气相色谱串联质谱法测定水体中10种多溴联苯醚

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现代化工 2024年第S01期44卷 368-371页

作者：刘磊杨继伟李剑童文烽徐巧俞晓峰杭州谱育科技发展有限公司浙江杭州311305

建立了气相色谱串联质谱法快速测定水体中10种多溴联苯醚(PBDEs)含量的分析方法。使用10%样品体积的二氯甲烷溶液进行液液萃取,重复2次,合并的萃取液经减压浓缩后使用二氯甲烷复溶;采用15 m的DB-5 HT色谱柱分离,在280℃进样口温度、1.8 ... 详细信息

建立了气相色谱串联质谱法快速测定水体中10种多溴联苯醚(PBDEs)含量的分析方法。使用10%样品体积的二氯甲烷溶液进行液液萃取,重复2次,合并的萃取液经减压浓缩后使用二氯甲烷复溶;采用15 m的DB-5 HT色谱柱分离,在280℃进样口温度、1.8 mL/min氦气流速、320℃离子源与GC接口温度、离子监测模式等条件下进行测定。方法学验证结果表明,10种多溴联苯醚在0.5~150 ng/L质量浓度范围内决定系数R^(2)>0.9990,检出限在0.14~1.89 ng/L,回收率在84.06%~106.99%,精密度在0.96%~5.43%(n=6)。该方法操作简便快速、灵敏度高、稳定性好,适用于水中10种多溴联苯醚化合物含量的快速测定。实际样品测试结果显示,海水中未检出PBDEs,生活污水及养殖废水中PBDEs含量在0.13~0.35 ng/L。

关键词：液液萃取气相色谱串联质谱多溴联苯醚水体

托珠单抗在儿童风湿免疫性疾病中应用的安全性研究

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中国新药与临床杂志 2024年第6期43卷 426-431页

作者：刘红霞谢婷朱彦谭波宇杨巧玲郝胜上海市儿童医院/上海交通大学医学院附属儿童医院药学部上海200062 上海市儿童医院/上海交通大学医学院附属儿童医院肾脏风湿免疫科上海200062

目的分析托珠单抗在儿童风湿免疫性疾病中应用的安全性,为临床用药提供参考。方法收集2016年1月1日—2022年8月9日使用托珠单抗治疗风湿免疫性疾病患儿的临床资料,对不良事件(AE)的发生率及影响因素、分布、发生时间和转归等进行回顾性... 详细信息

目的分析托珠单抗在儿童风湿免疫性疾病中应用的安全性,为临床用药提供参考。方法收集2016年1月1日—2022年8月9日使用托珠单抗治疗风湿免疫性疾病患儿的临床资料,对不良事件(AE)的发生率及影响因素、分布、发生时间和转归等进行回顾性分析。结果共纳入53例使用托珠单抗治疗的患儿,全身型幼年特发性关节炎48例、干燥综合征1例、自身免疫疾病(自身炎症性疾病)2例、幼年特发性关节炎(多关节型)1例。多发性大动脉炎1例,AE发生率为87%(46/53),主要AE为高甘油三酯血症(60%)、肝损伤(49%)、高胆固醇血症(30%)、高胆红素血症(8%)、中性粒细胞减少(9%)、超敏反应(8%)等。导致停药的主要AE为超敏反应,高胆固醇血症的发生与更高的给药剂量相关,肝损伤的发生与更高年龄和更高体重指数相关。AE大部分较轻,可自行恢复正常,持续用药率96%(44/46)。结论儿童使用托珠单抗治疗后相关AE发生率较高,超敏反应可导致停药,用药期间需要予以关注。虽然大部分患儿只发生轻度肝损伤,仍需警惕严重肝衰竭的发生可能。

关键词：托珠单抗安全血脂异常化学性与药物性肝损伤自身免疫疾病超敏反应

Engineering Cu^(+)/CeZrO_(x) interfaces to promote CO_(2) hydrogenation to methanol

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Journal of Energy Chemistry 2023年第2期77卷 45-53,I0002页

作者： Jingpeng Zhang Xiaohang Sun Congyi Wu Wenquan Hang Xu Hu Dawei qiao Binhang Yan Department of Chemical Engineering Tsinghua UniversityBeijing 100084China School of Science China University of GeosciencesBeijing 10084China Jiangsu Huadian Jurong Power Station Co.LTD Zhenjiang 212000JiangsuChina

Cu-based catalysts are widely employed for CO_(2) hydrogenation to methanol,which is expected as a promising process to achieving carbon ***,most Cu-based catalysts still suffer from low methanol yield with a passable CO_(2) conversion and lack insight into its reaction mechanism for guiding the design of *** this work,Cu^(+)/CeZrO_(x) interfaces are engineered by employing a series of ceria-zirconia solid solution catalysts with various Ce/Zr ratios,forming a Cu^(+)-O_(v)-Ce^(3+)structure where Cu^(+)atoms are bonded to the oxygen vacancies(O_(v))of *** to Cu/CeO_(2) and Cu/ZrO_(2),the optimized catalyst(i.e.,Cu_(0.3)Ce_(0.3)Zr_(0.7))exhibits a much higher mass-specific methanol formation rate(192g_(MeOH)/kg_(cat)/h)at 240℃and 3 *** a series of in-situ and ex-situ characterization,it is revealed that oxygen vacancies in solid solutions can effectively assist the activation of CO_(2) and tune the electronic state of copper to promote the formation of Cu^(+)/CeZrO_(x) interfaces,which stabilizes the key*CO intermediate,inhibits its desorption and facilitates its further hydrogenation to methanol via the reverse watergas-shift(RWGS)+CO-Hydro ***,the concentration of*CO or the apparent Cu^(+)/(Cu^(+)+Cu^(0))ratio could be employed as a quantitative descriptor of the methanol formation *** work is expected to give a deep insight into the mechanism of metal/support interfaces in CO_(2) hydrogenation to methanol,offering an effective strategy to develop new catalysts with high performance.

关键词： CO_(2)hydrogenation Methanol synthesis In-situ characterization Cu^(+)/CeZrO_(x)interfaces Oxygen vacancies