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Study on the DOP of Output Pulse in Optical Fiber Transmission Systems

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光学学报 2003年第S1期23卷 65-66页

作者： Yingwu Zhou Lingwei Guo Rui Huang Ronghui qu Zujie fang (Shanghai Institute of Optics & Fine Mechanics,The Chinese Academy of Sciences,P.R.C. Shanghai Institute of Optics and Fine Mechanics The Chinese Academy of Sciences P. R. C.

In this paper the expression of the output pulse Stokes vector is derived based on the Jones matrix model proposed by *** et al. The basic properties of degree of polarization (DOP) for output pulse are investigated.

关键词： optical fiber communication system polarization mode dispersion degree of polarization.

A chiral fluorescent probe for molecular recognition of basic amino acids in solutions and cells

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Chinese Chemical Letters 2024年第10期35卷 390-395页

作者： Chuan-Zhi Ni Ruo-Ming Li fang-Qi Zhang qu-Ao-Wei Li Yuan-Yuan Zhu Jie Zeng Shuang-Xi Gu School of Chemistry and Environmental Engineering School of Chemical Engineering & Pharmacy Pharmaceutical Research Institute Hubei Key Laboratory of Novel Reactor and Green Chemical Technology Wuhan Institute of Technology Nanjing Pusheng Biomedical Co. Ltd.

A novel and readily available binaphthyl-based fluorescent probe（S）-1 was designed and synthesized.（S）-1 can be used to not only chemoselectively discriminate 3 basic amino acids out of common amino acids, but also enantioselectively recognize histidine. Encouragingly, enantioselective imaging of histidine in cells was achieved for the first time by the probe（S）-1. These performances endowed it potential application in the chiral analysis of basic amino acids in asymmetric synthesis and cell imaging for diagnosis of diseases caused by racemization of histidine. Nuclear magnetic resonance（NMR） and mass spectrometry investigations suggested that different reaction extent of（S）-1 with L/D-histidine and different product structures generated the observed enantioselective fluorescent response. The molecular structures and thermodynamic stability of the complexes, formed from（S）-1 + Zn2+and enantiomers of histidine, were calculated by Gaussian 16 based on density functional theory（DFT） to validate the above action mechanism.

关键词： Basic amino acids Cell imaging Chemoselectivity Chiral recognition Enantioselectivity Fluorescent probe

CeO_2掺杂对BaTiO_3基陶瓷电介质的影响

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压电与声光 2007年第1期29卷 77-79页

作者：张晨曲远方单丹天津大学先进陶瓷与加工技术教育部重点实验室天津300072

研究采用固相法在BaTiO3中掺杂不同含量的CeO2对体系介电性能及微观结构的影响,讨论了不同烧结温度下体系介电性能的变化。研究发现,当组成为Ba(Ce0.08Ti0.92)O3时,试样在1 490℃保温2 h中可获得性能优良的电容器介质材料。体系的相对... 详细信息

研究采用固相法在BaTiO3中掺杂不同含量的CeO2对体系介电性能及微观结构的影响,讨论了不同烧结温度下体系介电性能的变化。研究发现,当组成为Ba(Ce0.08Ti0.92)O3时,试样在1 490℃保温2 h中可获得性能优良的电容器介质材料。体系的相对介电系数可达5 300,介质损耗仅为2.42%,绝缘电阻率为1.39×107Ω.cm,居里温度向室温方向移动至45℃。与此同时,借助扫描电镜对烧结体进行了微观形貌分析。结果表明,CeO2掺杂使Ce4+部分取代Ti4+,有效地增加了体系的相对介电系数,降低了介质损耗,并起到了良好的居里峰展宽及移峰效应。此外,CeO2掺杂亦可抑制晶粒的异常长大,得到较高致密度的烧结体。

关键词：钛酸钡氧化铈介电性能微观形貌

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几个苹果品种在豫西栽培的注意事项

北方果树 2024年第2期 46-47,50页

作者：刘俊灵李红光瞿振芳韩立新郝贝贝陈博薛嫚娜三门峡市农业科学研究院河南三门峡472000 河南省苹果栽培工程技术研究中心河南三门峡472000 灵宝市西阎乡人民政府河南灵宝472500

近年来,豫西引进和推广了几个苹果新优品种,提高了当地果农的经济效益。但是,新品种在种植过程中存在一些问题,需要进一步完善栽培管理技术。作者针对不同品种在生产中出现的问题提出相应的注意事项,供当地果农参考。

关键词：豫西苹果品种注意事项

Electroacupuncture at Sensitized Acupoints Relieves Somatic Referred Pain in Colitis Rats by Inhibiting Sympathetic-Sensory Coupling to Interferewith 5-HT Signaling Pathway

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Chinese Journal of Integrative Medicine 2024年第2期30卷 152-162页

作者： YANG Ying qu Jin-yu GUO Hua ZHOU Hai-ying RUAN Xia PENG Ying-chun SHEN Xue-fang XIONG Jin WANG Yi-li School of Clinical Medicine Chengdu Medical CollegeChengdu(610500)China Department of Rehabilitation Medicine the First Affliated Hospital of Chengdu Medical CollegeChengdu(610500)China Department of Rehabilitation Medicine West China HospitalSichuan University/West China School of NursingSichuan UniversityChengdu(610041)China Department of Neurology the First Affiliated Hospital of Chengdu Medical CollegeChengdu(610500)China

Objective:To investigate whether electroacupuncture(EA) at sensitized acupoints could reduce sympathetic-sensory coupling(SSC) and neurogenic inflammatory response by interfering with 5-hydroxytryptamine(5-HT)ergic neural pathways to relieve colitis and somatic referred pain,and explore the underlying ***:Rats were treated with 5% dextran sodium sulfate(DSS) solution for 7 days to establish a colitis *** rats were randomly divided into the control and model groups according to a random number table(n=6).According to the Research on Rat Acupoint Atlas",sensitized acupoints and non-sensitized acupoints were *** were randomly divided into the control,model,Zusanli-EA(ST 36),Dachangshu-EA(BL 25),and Xinshu(BL 15) groups(n=6),as well as the control,model,EA,and EA+GR113808(a 5-HT inhibitor)groups(n=6).The rats in the control group received no *** was administered on 2 days after modeling using the stimulation pavameters:1 mA,2 Hz,for 30 min,with sparse and dense waves,for 14 consecutive ***113808 was injected into the tail vein at 5 mg/kg before EA for 10 min for 7 consecutive *** sensitivity was assessed with von Frey *** weight and disease activity index(DAI) scores of rats were *** and eosin staining was performed to observe colon *** was analyzed by immunofluorescence *** staining was performed to detect 5-HT and substance P(SP) *** calcitonin gene-related peptide(CGRP) in skin tissue and tyrosine hydroxylase(TH) protein levels in DRG were detected by Western *** levels of hyaluronic acid(HA),bradykinin(BK),prostaglandin I2(PGI2) in skin tissue,5-HT,tryptophan hydroxylase 1(TPH1),serotonin transporters(SERT),5-HT 3 receptor(5-HT3R),and 5-HT 4 receptor(5-HT4R) in colon tissue were measured by enzyme-linked immunosorbent assay(ELISA).Results:BL 25 and ST 36 acupoints were determined as sensitized acupoints,and BL 1

关键词： electroacupuncture sensitized acupoints sympathetic-sensory coupling 5-hydroxytryptamine neurogenic inflammation somaticreferredpain

The Relationship Between Gene Mutation and Pathological Type of Lung Cancer

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Chinese Journal of Biomedical Engineering(English Edition) 2018年第2期27卷 47-56页

作者： PANG Feng-rui qu fang WU Bin ZHA Wen-ting LV Yuan Department of Epidemiology and Health Statistics Medical College of Hunan Normal University

Objective: To investigate the relationship between gene mutation and pathological type of lung cancer, inspect and verify the consistency between homologous genes mutation in various pathologic type. Methods: Combined with the COSMIC and Uni Prot database, we obtained the reported overall big-sample mutation data of lung cancer and the protein sequences of the top 20 mutated genes,respectively. Analyze the data and cluster the protein sequences and then deduce the homologous gene. Ultimately, analyze the mutations of different pathological types of homologous genes. Results: TP53(32.32%) has the highest mutation rate in lung cancer, followed by EGFR(29.12%). The copy number variability(CNV) of genes:KRAS, LRP1 B, CDKN2 A, KMT2 C, FAT1, PIK3 CA, RB1, ERBB4, GRIN2 A and KDR between each pathological type is statically significant(Pquamous carcinoma of gene TP53, KRAS, LRP1 B, CDKN2 A, STK11, FAT4, KMT2 D, NFE2 L2, KEAP1,PIK3 CA, RB1, ERBB4, SMARCA4 and KDR are statistically significant(Pquence of EGFR and ERBB4 can reach 93%, and FAT4 and FAT1 are 81%. For small cell carcinoma, there's no difference in CNV between the two groups of homologous genes, and no difference between FAT4 and FAT1 in adenocarcinoma. Conclusion: The CNV and gene expression of lung cancer-associated genes are relevant to pathologic types. GFR and ERBB4 are homologous, FAT4 and FAT1 are also among the top 20 mutation ***, there's no difference in CNV between the two groups of small cell carcinoma, which is the same between FAT4 and FAT1 in adenocarcinoma.

关键词： lung cancer pathologic typing gene mutation

Combining lymph node ratio to develop prognostic models for postoperative gastric neuroendocrine neoplasm patients

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3507-3520页

作者： Wen Liu Hong-Yu Wu Jia-Xi Lin Shu-Ting qu Yi-Jie Gu Jin-Zhou Zhu Chun-fang Xu Department of Gastroenterology Changzhou Hospital of Traditional Chinese MedicineChangzhou 213000Jiangsu ProvinceChina Department of Gastroenterology The First Affiliated Hospital of Soochow UniversitySuzhou 215006Jiangsu ProvinceChina Department of Gastroenterology Suzhou Ninth Hospital Affiliated to Soochow UniversitySuzhou 215200Jiangsu ProvinceChina

BACKGROUND Lymph node ratio(LNR)was demonstrated to play a crucial role in the prognosis of many ***,research concerning the prognostic value of LNR in postoperative gastric neuroendocrine neoplasm(NEN)patients was *** To explore the prognostic value of LNR in postoperative gastric NEN patients and to combine LNR to develop prognostic *** A total of 286 patients from the Surveillance,Epidemiology,and End Results database were divided into the training set and validation set at a ratio of 8:2.92 patients from the First Affiliated Hospital of Soochow University in China were designated as a test *** regression analysis was used to explore the relationship between LNR and disease-specific survival(DSS)of gastric NEN *** survival forest(RSF)algorithm and Cox proportional hazards(CoxPH)analysis were applied to develop models to predict DSS respectively,and compared with the 8th edition American Joint Committee on Cancer(AJCC)tumornode-metastasis(TNM)*** Multivariate analyses indicated that LNR was an independent prognostic factor for postoperative gastric NEN patients and a higher LNR was accompanied by a higher risk of *** RSF model exhibited the best performance in predicting DSS,with the C-index in the test set being 0.769[95%confidence interval(CI):0.691-0.846]outperforming the CoxPH model(0.744,95%CI:0.665-0.822)and the 8th edition AJCC TNM staging(0.723,95%CI:0.613-0.833).The calibration curves and decision curve analysis(DCA)demonstrated the RSF model had good calibration and clinical ***,the RSF model could perform risk stratification and individual prognosis prediction *** A higher LNR indicated a lower DSS in postoperative gastric NEN *** RSF model outperformed the CoxPH model and the 8th edition AJCC TNM staging in the test set,showing potential in clinical practice.

关键词： Gastric neuroendocrine neoplasm Lymph node ratio Disease-specific survival Random survival forest Predictive model

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Tricomi算子的基本解

数学学报（中文版） 2008年第4期51卷 625-632页

作者：屈爱芳复旦大学数学科学学院上海200433

考虑含三个自变量的Tricomi方程Tu=y(u_(x_1x_1)+u_(x_2x_2))+u_(yy)=0 (1)奇点为(a,b,0)的基本解.相对于两维的Tricomi方程,由于其奇性的增强,用通常的分布论计算基本解时,得到的积分发散,以致无法用该方法得到基本解,此时有必要引入... 详细信息

考虑含三个自变量的Tricomi方程Tu=y(u_(x_1x_1)+u_(x_2x_2))+u_(yy)=0 (1)奇点为(a,b,0)的基本解.相对于两维的Tricomi方程,由于其奇性的增强,用通常的分布论计算基本解时,得到的积分发散,以致无法用该方法得到基本解,此时有必要引入散度积分主部来定义分布论中的基本解.我们利用特征线法在Cauchy主值意义下求得其基本解.

关键词：基本解 Tricomi方程特征线法

利用UML技术建立图书馆个性化推送系统模型

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现代图书情报技术 2005年第5期 27-29页

作者：渠芳孙涌徐州师范大学图书馆徐州221116 苏州大学计算机科学与技术学院苏州215006

简单概述了图书馆个性化服务的内容,并利用统一建模语言UML及ROSE工具进行了系统分析建模。系统建模过程中利用了UML的用例图对系统进行分析,利用交互图、组件类图、组件图进行了系统设计。

关键词： UML 个性化推送图书馆模型