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A low-power Bluetooth-based wireless sensor network and its global confliction-solving impact localization method

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Chinese Journal of Aeronautics 2024年第1期37卷 153-161页

作者： Yuanjia WANG lei qiu Qiyun XU Liming SHI College of Aerospace Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China Department of Electrical and Electronic Engineering University of EdinburghEdinburgh EH89YLUK

During the whole service lifetime of aircraft structures with composite materials,impacts are inevitable and can usually cause severe but barely visible *** the occurrences of impact are random and unpredictable,it is a hotspot direction to develop an online impact monitoring system that can meet strict limitations of aerospace applications including small size,light weight,and low power ***(PZT)sensor,being able to generate impact response signals with no external power and cover a large-scale structure with only a small amount of them,is a promising ***,for real systems,networks with multiple nodes are normally required to monitor large-scale structures in a global way to identify any impact localization confliction,yet the existing studies are mostly evaluated with single nodes instead of ***,in this paper,based on a new low-power node designed,a Bluetooth-based digital impact monitoring PZT sensor network is proposed for the first time with its global confliction-solving impact localization *** of the system as a network are researched and analyzed on a complex real aircraft wing box for a global confliction-solving impact localization,showing a satisfying high accuracy.

关键词： Bluetooth-based low-power design Confliction-solving evaluation Complex composites Piezoelectric sensors Wireless impact monitoring network

Histone variant H2A.Z facilitates DNA replication

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Science China(Life Sciences) 2020年第5期63卷 788-790页

作者： lei qiu Xinyi Zeng Junhong Han Department of Abdominal Oncology State Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan Universityand Collaborative Innovation Center for BiotherapyChengdu 610041China

In eukaryotes,DNA wraps around the histone octamer to form nucleosomes,which are further compacted into the chromosome *** chromosome contains multiple replication origins that are regulated by both DNA sequence and e... 详细信息

关键词： structure. H2A.Z DNA

Maternally inherited H4K16 acetylation primes zygotic gene activation in Drosophila

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Science China(Life Sciences) 2020年第12期63卷 1950-1952页

作者： lei qiu Xueqin Liu Junhong Han Research Laboratory of Tumor Epigenetics and Genomics Department of General SurgeryFrontiers Science Center for Disease-related Molecular NetworkState Key Laboratory of Biotherapy and Cancer Centerand National Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengdu 610041China Department of Clinical Research Management West China HospitalSichuan UniversityChengdu 610041China

In a recent study published in Cell, Samata et al. demonstrated a novel mechanism that guided the genomic reprogramming. They showed that the acetylation of histone H4 at Lysine 16(H4K16ac) was intergenerationally maintained from the mother’s oocyte to the young embryo and primed zygotic gene activation in Drosophila(Samata et al., 2020).Embryonic development is initially directed by maternal gene products. Then gradually, developmental control is handed to the zygotic genome during the maternal-to-zygotic transition(MZT).

关键词： activation maintained initially

Multiphysics simulation method of Lamb wavepropagation with piezoelectric transducers under load condition

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Chinese Journal of Aeronautics 2019年第5期32卷 1071-1086页

作者： lei qiu Xixi YAN Xiaodong LIN Shenfang YUAN Research Center of Structural Health Monitoring and Prognosis State Key Lab of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and Astronautics

Lamb Wave(LW) simulation under time-varying conditions is an effective and low cost way to study the problem of the low reliability of the structural health monitoring methods based on the LW and Piezoelectric Transducer(PT). In this paper, a multiphysics simulation method of the LW propagation with the PTs under load condition is proposed. With this method, two key mechanisms of the load influence on the LW propagation are considered and coupled with each other. The first mechanism is the acoustoelastic effect which is the main reason of the LW velocity change. The second key mechanism is the load influence on piezoelectric materials, which results in a change of the amplitude. Based on the computational platform of the COMSOL Multiphysics, a multiphysics simulation model of the LW propagation with the PTs under load condition is established. The simulation model includes two physical phenomena. The first one is called solid mechanics, which is used to simulate the acoustoelastic effect being combined with the hyperelastic material properties of the structure in which the LW propagates. The second one is called electromechanical coupling, which considers the simulation of the piezoelectric effect of the PTs for the LW excitation and sensing. To simulate the load influence on piezoelectric materials, a non-linear numerical model of the relationship between the load and the piezoelectric coefficient d31 is established based on an experiment of the load influence on the LW. The simulation results under uniaxial tensile load condition are obtained and are compared with the data obtained from the experiment. It shows that the variations of the phase velocity and amplitude of the LW obtained from the simulation model match the experimental results well.

关键词： Acoustoelastic effect Lamb wave Multiphysics simulation Piezoelectric coefficient Structural health monitoring Time-varying condition

A pilot study of catching high-z GRBs and exploring circumburst environment in the forthcoming SVOM era

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Research in Astronomy and Astrophysics 2020年第8期20卷 211-216页

作者： Jing Wang Yu-lei qiu Jian-Yan Wei Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China

Rapid spectroscopy of GRB afterglows is an important and hard *** on the archival XSGRB spectral database,we here perform a pilot study on the afterglow's spectroscopy in the forthcoming SVOM era in two ***,our simulation indicates that the color acquired from the SVOM/VT blue and red channels is effective in discriminating between low-z(z≤3)and distant GRB candidates until z^***,by doubling the sample size,we find that the previously proposed global photoionization response of the circumburst gas to the prompt emission(i.e.,the CIV/CII-L(iso)/E2peak relationship)is roughly *** the confirmation is dissatisfactory at the large L(iso)/E2peak *** believe that this issue can be further addressed in the SVOM era by a larger spectroscopy sample,thanks to its capability of rapid identification of optical candidates of afterglow and its anti-solar pointing strategy.

关键词： gamma ray bursts:general techniques:photometric techniques:spectroscopic methods:statistical

Does the Amati Relation depend on the Luminosity of the GRB's Host Galaxy?

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Chinese Journal of Astronomy and Astrophysics 2008年第3期8卷 255-261页

作者： Jing Wang Jing-Song Deng Yu-lei qiu National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China

In order to test the systematics of the Amati relation, 24 long-duration GRBs with available Eγ,iso and Ep are separated into two subgroups according to the B-band luminosity of their host galaxies. The Amati relations in the two subgroups are found to be in agreement with each other within the uncertainties. Taking into account of the well established luminosity - metallicity relation of galaxies, no strong evolution of the Amati relation with the GRB＇s environmental metaUicity is implied in this study.

关键词： gamma-rays bursts -- gamma-rays observations -- galaxies evolution

STING cg16983159 methylation:a key factor for glioblastoma immunosuppression

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Signal Transduction and Targeted Therapy 2022年第8期7卷 2638-2640页

作者： lei qiu Yang Meng Junhong Han Research Laboratory of Tumor Epigenetics and Genomics Frontiers Science Center for Disease-related Molecular NetworkState Key Laboratory of Biotherapy and Cancer Centerand National Clinical Research Center for GeriatricsWest China HospitalSichuan University610041 ChengduP.R.China

In a recent study published in Cancer Cell,Low et *** a light on a novel DNA methylation pattern in the promoter region of the stimulator of interferon genes(STING),which may be a key factor for the“cold”tumor micro-environment(TME)of glioblastoma(GBM),contributing to its immunosuppression.1 They have demonstrated that STING expression is epigenetically silenced by cg16983159 methylation in glioma cells as well as normal brain cells and this silencing can be rescued by DNA methyltransferase(DNMT)inhibition(Fig.1).

关键词： al. interferon glioblastoma

Pharmacological Effects of Botanical Drugs on Myocardial Metabolism in Chronic Heart Failure

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Chinese Journal of Integrative Medicine 2024年第5期30卷 458-467页

作者： HU Yu-xuan qiu Sheng-lei SHANG Ju-ju WANG Zi LAI Xiao-lei Beijing Hospital of Traditional Chinese Medicine Capital Medical UniversityBeijing 100010China

Although there have been significant advances in the treatment of heart failure in recent years,chronic heart failure remains a leading cause of cardiovascular disease-related *** studies have found that targeted cardiac metabolic remodeling has good potential for the treatment of heart ***,most of the drugs that increase cardiac energy are still in the theoretical or testing *** research has found that botanical drugs not only increase myocardial energy metabolism through multiple targets but also have the potential to restore the balance of myocardial substrate *** this review,we summarized the mechanisms by which botanical drugs(the active ingredients/formulas/Chinese patent medicines)improve substrate utilization and promote myocardial energy metabolism by activating AMP-activated protein kinase(AMPK),peroxisome proliferator-activated receptors(PPARs)and other related *** the same time,some potential protective effects of botanical drugs on myocardium,such as alleviating oxidative stress and dysbiosis signaling,caused by metabolic disorders,were briefly discussed.

关键词： botanical drugs chronic heart failure myocardial metabolism pharmacological effects review

Two new species of the genus Libnotes Westwood(Diptera: Limoniidae) from China, with a key to Chinese species

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Zoological Systematics 2015年第1期40卷 79-85页

作者： qiu-lei Men School of Life Sciences Anqing Normal University

Two new species of the genus Libnotes Westwood, 1876, L. （Libnotes） wanensis sp. nov. and L. （L.） pseudonohirai sp. nov. from Southern China （Anhui） are described and illustrated here. A key to all of Chinese species in the subgenus Libnotes （Libnotes） is provided. The type specimens of the new species are deposited in the animal specimen room, School of Life Sciences, Anqing Normal University, Anhui Province, China.

关键词： Nematocera Tipuloidea Limoniidae Libnotes new species.