检索结果-南通市图书馆

Effect on serum metabolomics of rats with premature ovarian insufficiency by Zhibian(BL54) through Shuidao(ST28) acupuncture

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medicine 2024年第4期44卷 722-733页

作者： yan Jing FENG Huimin qiu Fang WANG Haijun YIN Luyun JIN Xiaofei ZHAO Jiyu WANG Hongyang yan Xiaoqin Second Clinical College of Shanxi University of Traditional Chinese Medicine Jinzhong 030619China Research Center of Experimental Acupuncture Science Tianjin University of Traditional Chinese MedicineTianjin 301617China Department of Cervical and Lumbar Vertebral Diseases Jinzhong Hospital Affiliated to Shanxi University of Traditional Chinese MedicineJinzhong 030600China

OBJECTIVE:To analyze the serum metabolic targets of the"Zhibian(BL54)through Shuidao(ST28)"acupuncture technique in cyclophosphamide(CTX)-induced premature ovarian insufficiency(POI)model rats and to elucidate the potential molecular mechanism of acupuncture in improving ***:We used an intraperitoneal injection of CTX to establish the POI rat model(POI group)and compared serum hormone levels and ovarian histopathological changes to evaluate the effect of the Zhibian(BL54)through Shuidao(ST28)technique(ZS+POI group)on ovarian ***,nontargeted metabolomics was performed using rat serum by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry(UPLC-Q-TOF/MS).RESULTS:After acupuncture intervention,the serum hormone levels and ovarian pathological morphology of POI rats were effectively ***,UPLC-Q-TOF/MS results showed that the ZS+POI group showed a significant reversal of the levels of 6 differential *** them,the levels of four serum metabolic markers,divanillyltetrahydrofuran ferulate,trans-ferulic acid,tryptamine,and neuraminic acid,increased *** analysis of biological effects showed that all metabolites were involved in the regulation of reproductive hormone levels and antioxidant and antiapoptotic ***:The"Zhibian(BL54)through Shuidao(ST28)"acupuncture method may improve the ovarian function of POI rats by regulating serum metabolite markers to exert antioxidant and antiapoptotic effects,which provides a theoretical basis for the clinical application of acupuncture in the treatment of POI.

关键词： acupuncture premature ovarian insufficiency metabolomics ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry Zhibian(BL54)through Shuidao(ST28)

Controlling solid form and crystal habit of triphenylmethanol by antisolvent crystallization in a microfluidic device

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2024年第4期35卷 393-398页

作者： Jun Lu Jinrui yan Yaohao Guo Junjie qiu Shuangliang Zhao Bo Bao East China University of Science and Technology Shanghai 200237China Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology and School of Chemistry and Chemical Engineering Guangxi UniversityNanning 530004China

Crystal habit and crystal form are critical elements in determining product properties and functions. In this work, we developed a microfluidic antisolvent crystallization technique to rapidly screen and accurately control the solid form and crystal habit of triphenylmethanol(Ph_(3)COH). This advanced technique separates the primary mixing of solutions from crystal formation(nucleation and growth) by introducing the microfluidic device, avoiding clogging in microchannels to obtain high-quality crystals. The results show that we can achieve controllable preparation of pure 2Ph_(3)COH·DMSO(DMSO solvate), pure Ph_(3)COH(form β), and mixed crystals with different mass ratios. Moreover, the microscale can prompt the DMSO solvate to grow into hexagonal sheet-like and bulk crystals. We can regulate the aspect ratio of hexagonal sheet-like crystals in binary solvents and control the crystal habit of the form β to transition between long needle-like shapes and short hexagonal prisms in DMF-H_(2)O. Meanwhile, we revealed that the solvent ratio, the antisolvent flow rate, and the initial concentration of Ph_(3)COH are the main factors affecting the solid form selectivity and morphology transition. Such a novel method would be considered as a promising technique to be extended to screen and control key crystallization parameters of other substances.

关键词： Microfluidics Triphenylmethanol Antisolvent crystallization Crystal habit Solid form

Thermally Conductive,Healable Glass Fiber Cloth Reinforced Polymer Composite based onβ-Hydroxyester Bonds Crosslinked Epoxy with Improved Heat Resistance

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第5期42卷 643-654,I0009页

作者： Fang Chen Xiao-yan Pang Ze-Ping Zhang Min-Zhi Rong Ming-qiu Zhang Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education GD HPPC LabIGCMESchool of ChemistrySun Yat-sen UniversityGuangzhou510275China Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center Jieyang515200China

To simultaneously endow thermal conductivity,high glass transition temperature(Tg)and healing capability to glass fiber/epoxy(GFREP)composite,dynamic crosslinked epoxy resin bearing reversibleβ-hydroxyl ester bonds was reinforced with boron nitride nanosheets modified glass fiber cloth(GFC@BNNSs).The in-plane heat conduction paths were constructed by electrostatic self-assembly of polyacrylic acid treated GFC and polyethyleneimine decorated ***,the GFC@BNNSs were impregnated with the mixture of lower concentration(3-glycidyloxypropyl)trimethoxysilane grafted BN micron sheets,3,4-epoxycyclohexylmethyl 3,4-epoxycyclohexanecarboxylate and hexahydro-4-methylphthalic anhydride,which accounted for establishing the through-plane heat transport pathways and avoiding serious deterioration of mechanical *** resultant GFREP composite containing less boron nitride particles(17.6 wt%)exhibited superior in-plane(3.29 W·m^(-1)·K^(-1))and through-plane(1.16 W·m^(-1)·K^(-1))thermal conductivities,as well as high Tg of 204℃(Tg of the unfilled epoxy=177℃).The reversible transesterification reaction enabled closure of interlaminar cracks within the composite,achieving decent healing efficiencies estimated by means of tensile strength(71.2%),electrical breakdown strength(83.6%)and thermal conductivity(69.1%).The present work overcame the disadvantages of conventional thermally conductive composites,and provided an efficient approach to prolong the life span of thermally conductive GFREP laminate for high-temperature resistant integrated circuit application.

关键词： Thermally conductive composites Boron nitride High-temperature resistance β-Hydroxyl ester bond Healing

Understanding livelihood vulnerability:a perspective from Western Sichuan’s ethnic rural settings

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第2期21卷 380-396页

作者： YU Yongqian JING Zheng WANG yan qiu Xiaoping yanG Xueting XU Yun School of Geography and Resource Science Sichuan Normal UniversityChengdu 610101China Key Laboratory of land Resources Evaluation and Monitoring in Southwest Ministry of EducationSichuan Normal UniversityChengdu 610101China Sichuan County Economic Development Research Center Mianyang Normal UniversityMianyang 621000China Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610041China

To explore the livelihood status and key influencing factors of rural households in the minority areas,we collected flat data from 284 rural households in 32 villages across 12 counties of Western Sichuan from 2021 to *** conducted participatory household survey on the livelihood status of the rural households and try to identify the key factors to influence their livelihood vulnerability using multiple linear *** results showed that:the livelihood situation of the rural households is relatively *** vulnerability varies significantly with the income levels,education levels,and income *** vulnerability of farm households,categorized from low to high livelihood types,follows the sequence:non-agricultural dominant households,non-agricultural households,agricultural dominant households,and pure agricultural *** degree of damage to the natural environment,education costs,loan opportunities,the proportion of agricultural income to annual household income,and the presence of sick people in the household have significant positive effects on the livelihood vulnerability index(LVI)of rural households;while help from relatives and friends,net income per capita,household size,household education,agricultural land area,participation in industrial organizations,number of livestock,purchase of commercial houses,drinking water source,and self-supply of food have significant negative *** on the findings,we believe that local rural households operate in a complex livelihood system and recommend continuous interventions targeting key influences to provide empirical research support for areas facing similar situations.

关键词： Livelihood Vulnerability Rural households Ethnic areas

Development and Deformation Characteristics of Large Ancient Landslides in the Intensely Hazardous Xiongba-Sela Section of the Jinsha River, Eastern Tibetan Plateau, China

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2024年第3期35卷 980-997页

作者： Yiqiu yan Changbao Guo yanan Zhang Zhendong qiu Caihong Li Xue Li Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China Key Laboratory of Active Tectonics and Geological Safety Ministry of Natural ResourcesBeijing 100081China

The upstream Jinsha River,located in the eastern Tibetan Plateau,has been experiencing intense geological hazards characterized by a high density of ancient landslides,significant deformation and reactivation *** this study,remote sensing interpretation,field investigations,and Small Baseline Subset Interferometric Synthetic Aperture Radar(SBAS-InSAR)technologies have been *** a 17 km stretch of the Jinsha River,specifically in the Xiongba-Sela segment,16 large-scale ancient landslides were identified,9 of which are currently undergoing creeping ***,the Sela and Xiongba ancient landslides exhibit significant deformation,with a maximum deformation rate of-192 mm/yr,indicating a high level of sliding *** volume of the Sela ancient landslide is estimated to be 1.8×108 to 4.5×108 m3,and characterized by extensive fissures and long-term creeping *** SBAS-InSAR results revealed significant spatial variations in the deformation of the Sela ancient landslide,generally displaying two secondary zones of intense deformation,and landslide deformation exhibits nonlinear behavior with *** January 2016 and February 2022,Zone III1 on the southwest side of the Sela ancient landslide,experienced a maximum cumulative deformation of-857 mm,with a maximum deformation rate of-108 mm/*** III2,on the northeast side of the Sela ancient landslide,the maximum cumulative deformation was-456 mm,with a maximum deformation rate of-74 mm/yr;among these,the H2 and H4 secondary bodies on the south side of III1 are in the accelerative deformation stage and at the Warn warning *** propose that the large-scale flood and debris flow disasters triggered by the Baige landslide-dammed lake-dam broken disaster chain in Tibetan Plateau during October and November 2018 caused severe erosion at the foot of downstream *** far-field triggering effect accelerated the creep of the downstream ancient ***,the defo

关键词： Jinsha River SBAS-InSAR landslides surface deformation disasters.

Effect of Tanshinone IIA on High Glucose-induced Apoptosis and Oxidative Stress Damage in Vascular Endothelial Cells

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Biomedical Engineering 2024年第2期33卷 62-68页

作者： qiu Shui-lin HUANG Rong HUANG Jian-qing qiu Rong-shui Longyan First Affiliated Hospital of Fujian Medical University Xiamen Medical College Affiliated Haicang Hospital

Objective: The primary cause of microvascular disease in diabetic complications is long-term hyperglycemia, wherein the damage and apoptosis of vascular endothelial cells play a significant role. Sodium tanshinone IIA sulfonate(STS) has been found to have beneficial effects on cardiovascular health. This study aimed to investigate the impact of STS on high glucose-induced apoptosis and oxidative stress damage in vascular endothelial cells, as well as its potential protective mechanisms. Methods:Human umbilical vein endothelial cells(HUVECs) were divided into five groups:low-glucose group, high-glucose group, and three STS groups(STS-a, STS-b, and STS-c). The low-glucose group was incubated with DMEM low-sugar medium containing 5.5 mmol·L-1glucose, while the high-glucose group was treated with 33.3mmol·L-1glucose. The STS groups were exposed to 10, 30, and 50 μg·m L-1of STS,respectively. Each group was cultured for 72 h, and the MTT method was utilized to assess cell proliferation. Additionally, flow cytometry was employed to monitor changes in cell apoptosis and cellular oxidative stress indicators at 24, 48, and 72 h of cell culture in each group. Results: As time went on, the cell proliferation ability and apoptosis rate of each group gradually increased. The high-glucose group exhibited lower proliferation ability compared to the other groups. The STS-c group demonstrated the highest OD value for proliferation ability(24 h: 1.19±0.12; 48 h: 1.20±0.13; 72 h:1.25 ±0.12), but it was still lower than that of the low-sugar group. Notably, the high-glucose group had the highest cell apoptosis rate, while the low-glucose group had the lowest. The apoptosis rate of the STS-c group(24 h: 8.02±0.13; 48 h: 10.10±0.12;72 h: 13.18 ±0.11)% was between that of the low-glucose group and the high-glucose group, and lower than the STS-a and STS-b groups. Furthermore, the high-glucose group exhibited the highest malondialdehyde and nitric oxide synthase activities, as well as super

关键词：

Effect of Mn content on microstructure and properties of AlCrCuFeMnx high-entropy alloy

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

China Foundry 2024年第2期21卷 147-158页

作者： Ning Wang Kai Ma qiu-da Li Yu-dong Yuan yan-chun Zhao Li Feng School of Materials Science and Engineering Lanzhou University of TechnologyLanzhou 730050China State Key Laboratory of Advanced Processing and Reuse of Nonferrous Metals Lanzhou 730050China CNNC Nuclear Power Operation and Management Co. Ltd.Haiyan 314300ZhejiangChina

AlCrCuFeMnx(x=0,0.5,1,1.5,and 2)high-entropy alloys were prepared using the vacuum arc melting *** microstructure and mechanical properties of AlCrCuFeMnxwere analyzed and tested by XRD,SEM,TEM,nanoindentation,and electronic universal *** results indicate that the AlCrCuFeMnxhigh-entropy alloy exhibits a dendritic structure,consisting of dendrites with a BCC structure,interdendrite regions with an FCC structure,and precipitates with an ordered BCC structure that form within the ***(Mn)has a strong affinity for dendritic,interdendritic,and precipitate structures,allowing it to easily enter these *** an increase in Mn content,the size of the precipitated nanoparticles in the dendritic region initially increases and then ***,the area fraction initially decreases and then ***,the alloy’s strength and wear resistance decrease,while its plasticity *** Al Cr Cu Fe Mn1.5alloy boasts excellent mechanical properties,including a hardness of 360 HV and a wear rate of 2.4×10^(-5)mm^(3)·N^(-1)·mm^(-1).It also exhibits impressive yield strength,compressive strength,and deformation rates of 960 MPa,1,700 MPa,and 27.5%,respectively.

关键词： high-entropy alloys microstructure mechanical properties wear resistance strengthening mechanisms

Ag-doped Ti3C2Tx sensor: A promising candidate for low-concentration H2S gas sensing

在线全文

学校读者我要写书评

暂无评论

HIGH VOLTAGE 2024年第3期9卷 537-545页

作者： Zeng, Fuping Feng, Xiaoxuan Chen, Xiaoyue qiu, Hao yan, Yiming Yao, Qiang Tang, Ju Wuhan Univ Sch Elect Engn & Automat Wuhan Peoples R China Hubei Key Lab Power Equipment & Syst Secur Integra Wuhan Peoples R China State Grid Chengdu Elect Power Supply Co Chengdu Peoples R China Chongqing Univ State Key Lab Power Transmiss Equipment Syst Secur Chongqing Peoples R China State Grid Chongqing Elect Power Res Inst Chongqing Peoples R China

Trace hydrogen sulphide (H2S) could reflect the severity of insulation faults in gas-insulated switchgear (GIS), therefore, accurate and fast detection of low-concentration H2S is important for on-line monitoring, fault diagnosis, and state evaluation in GIS. Ag-Ti3C2Tx chemiresistive-type sensors were fabricated via drop-coating with self-reduction synthesised Ag-doped Ti3C2Tx. The as-prepared sensors exhibited an excellent sensitivity and selectivity to H2S with an extremely low detection of limit of 18.57 parts per billion (ppb) at 25 degrees C (room temperature). The response of Ag-Ti3C2Tx sensor to 10 parts per million (ppm) H2S was enhanced similar to 12 times than that of the pristine Ti3C2Tx sensor. The compositing of Ti3C2Tx with Ag nanoparticles (NPs) enabled the fast response/recovery time for H2S detection. Further analysis found that the enhanced H2S sensing performances could be attributed to chemical sensitisation, adsorbed oxygen species regulation and high Brunauer-Emmett-Teller (BET) surface area. This study paves the way for Ag-Ti3C2Tx as room-temperature sensing materials to detect low-concentration H2S in GIS.

关键词： 2ND DISSOCIATION-CONSTANT PARTIAL DISCHARGE NEURAL-NETWORK DECOMPOSITION MOLECULES REMOVAL

Effects of organic fertilizers produced using different techniques on rice grain yield and ammonia volatilization in double-cropping rice fields

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pedosphere 2024年第1期34卷 110-120页

作者： Mingcheng HU Andrew JWADE Weishou SHEN Zhenfang ZHONG Chongwen qiu Xiangui lin Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control Collaborative Innovation Center of Atmospheric Environment and Equipment Technologyand School of Environmental Science and EngineeringNanjing University of Information Science and TechnologyNanjing 210044China Department of Geography and Environmental Science University of ReadingReading RG65DWUK Haina Research Institute of Guangdong Haina Agricultural Co. Ltd.Huizhou 516000China State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China

Ammonia(NH_(3)) volatilization from rice fields contributes to poor air quality and indicates low nitrogen use efficiency. Although organic fertilizers can meet the nitrogen requirement for rice growth, the simultaneous effects of organic fertilizers on NH_(3) volatilization and rice yield in paddy fields are poorly understood and quantified. To address this gap in our knowledge, experimental field plots were established in a conventional double-cropping paddy field in the Pearl River Delta region, southern China. Five fertilizer treatments were used besides the control with no fertilizer: fresh organic fertilizer, successively composted organic fertilizer, chemically composted organic fertilizer, mixture of chemically composted organic fertilizer with inorganic fertilizer, and chemical fertilizer. Ammonia volatilization was measured using a batch-type airflow enclosure method. No significant differences in grain yield were observed among organic and chemical fertilizer treatments. However, compared with chemical fertilizer, chemically composted organic fertilizer and successively composted organic fertilizer significantly decreased total NH_(3) volatilization by 70% and 68%, respectively. The ammonium-nitrogen concentration in field surface water correlated strongly(P < 0.01) and positively with NH_(3) volatilization across fertilization treatments. Our findings demonstrate that chemically composted organic fertilizer can sustain rice yield while reducing NH_(3) volatilization. An important future step is to promote these field measurements to similar rice cultivation areas to quantify the regional-and national-scale impact on air quality and nitrogen deposition in sensitive areas, and to design and implement better fertilizer management practices.

关键词： air quality crop production manure NH_(3)emission nitrogen use efficiency