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A systematic review of the effectiveness of clinical nurse specialist interventions in patients with chronic obstructive pulmonary disease(COPD)

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Frontiers of Nursing 2018年第2期5卷 147-156页

作者： Hua Yin ling Yang qiao Ye Department of Respiratory Medicine Zhuhai Peopled Hospital(The Third Hospital Affiliated to Jinan University)ZhuhaiGuangdong 519000China Nursing Department Zhuhai People's Hospital(The Third Hospital Affiliated to Jinan University)ZhuhaiGuangdong 519000China

Objective： This review aimed to examine the effectiveness of clinical nurse specialist （CNS） interventions in patients with chronic obstructive pulmonary disease （COPD）. COPD significantly affects people＇s health worldwide. With the development in nursing, CNSs are playing increasingly important roles in different departments. However, the studies on the effectiveness of CNSs in COPD are not as well organized as the studies on the effectiveness of CNSs in bronchiectasis and asthma. Therefore, this review aims to find some updated evidence on the CNS interventions for patients with COPD and on whether these interventions are ***： A narrative analysis of the data was performed for the eligible studies. Four databases were chosen： CINAHL, MEDLINE, British Nursing Index, and Cochrane Library. Other websites such as the National Institute for Health and Clinical Excellence, National Health Service Evidence, Association of Respiratory Nurse Specialists, and National Association of Clinical Nurse Specialist were searched as well. Two reviewers performed study identification independently, and all the retrieved articles were stored using the EndNote X7 software. The risk of bias in the included studies was assessed using the Cochrane Collaboration＇s risk of bias tool. Results： A total of nine studies were included in this review. There were five current interventions by CNSs for patients with COPD. These interventions were home nursing support, CNS]s supported discharge, multidisciplinary cooperation programs, nurse-led care programs, and self-care management education. The effectiveness of these five interventions was evaluated individually. There is low- to moderate-quality evidence indicating that home nursing support interventions may have a positive effect on mortality and quality of life. No significant difference in quality of life has been found between the CNS-supported discharge intervention and the usual

关键词： chronic obstructive pulmonary disease (COPD) clinical nurse specialists (CNSs) effectiveness systematic review advanced practice nurse RNS CNS led

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Regulation of electronic structure of monolayer MoS_(2) by pressure

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Rare Metals 2022年第5期41卷 1761-1770页

作者： qiao-Lu Lin Zheng-Fang Qian Xiang-Yu Dai Yi-ling Sun Ren-Heng Wang Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China

Understanding pressure-regulated electronic properties is crucial for integrating two-dimensional semiconductors into flexible electronic devices and pressure sensors. We thoroughly explored the tunability of the electronic structure of monolayer MoS_(2) upon the application of perpendicular pressure and shear stress by using first-principles calculations. The band gap increased at low pressures and then decreased as the pressure *** in the band gap are caused by the combined interaction of the increasing and decreasing trends in the band gap. The increase in the band gap is induced by the enhancement of the p–d orbital interaction at the top of the valence band(TVB). The delocalization of charge and unstable hybridization bonding causes a reduction in the band gap. The band gap under perpendicular pressure modes is closely related to the structural variation. Shear stress can effectively reduce the band gap with minimal change to the crystal structure. The maximum point at the TVB and the minimum point at the bottom of the conduction band are different for all pressure modes, resulting in various anisotropic properties. This study provides a theoretical basis for modulating the electrical and optical properties of monolayer MoS_(2).

关键词： Band gap Pressure Monolayer MoS_(2) Electronic structure Shear stress

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Carbon dioxide capture using polyethylenimine-loaded mesoporous carbons

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Journal of Environmental Sciences 2013年第1期25卷 124-132页

作者： Jitong Wang Huichao Chen Huanhuan Zhou Xiaojun Liu Wenming qiao Donghui Long Licheng ling State Key Laboratory of Chemical Engineering East China University of Science and Technology

A high efficiency sorbent for CO2 capture was developed by loading polyethylenimine （PEI） on mesoporous carbons which possessed well-developed mesoporous structures and large pore volume. The physicochemical properties of the sorbent were characterized by N2 adsorption/desorption, scanning electron microscopy （SEM）, thermal gravimetric analysis （TG） and Fourier transform infrared spectroscopy （FT-IR） techniques followed by testing for CO2 capture. Factors that affected the sorption capacity of the sorbent were studied. The sorbent exhibited extraordinary capture capacity with CO2 concentration ranging from 5% to 80%. The optimal PEI loading was determined to be 65 wt.% with a CO2 sorption capacity of 4.82 mmol-CO2/g-sorbent in 15% CO2/N2 at 75℃, owing to low mass-transfer resistance and a high utilization ratio of the amine compound （63%）. Moisture had a promoting effect on the sorption separation of CO2. In addition, the developed sorbent could be regenerated easily at 100℃, and it exhibited excellent regenerability and stability. These results indicate that this PEI-loaded mesoporous carbon sorbent should have a good potential for CO2 capture in the future.

关键词： carbon dioxide capture polyethylenimine mesoporous carbon amine utilization ratio

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Boosting High-Rate Zinc-Storage Performance by the Rational Design of Mn_(2)O_(3) Nanoporous Architecture Cathode

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Nano-Micro Letters 2020年第1期12卷 195-207页

作者： Danyang Feng Tu‑Nan Gao ling Zhang Bingkun Guo Shuyan Song Zhen‑An qiao Sheng Dai State Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of ChemistryJilin UniversityChangchun 130012JilinPeople’s Republic of China State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012JilinPeople’s Republic of China Materials Genome Institute Shanghai UniversityShanghai 200444People’s Republic of China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022People’s Republic of China Chemical Sciences Division Oak Ridge National LaboratoryOak RidgeTN 37831USA

Manganese oxides are regarded as one of the most promising cathode materials in rechargeable aqueous Zn-ion batteries(ZIBs)because of the low price and high ***,the practical application of Mn2O3 in ZIBs is still plagued by the low specific capacity and poor rate ***,highly crystalline Mn2O3 materials with interconnected mesostructures and controllable pore sizes are obtained via a ligand-assisted self-assembly process and used as high-performance electrode materials for reversible aqueous *** coordination degree between Mn2+and citric acid ligand plays a crucial role in the formation of the mesostructure,and the pore sizes can be easily tuned from 3.2 to 7.3 *** to the unique feature of nanoporous architectures,excellent zinc-storage performance can be achieved in ZIBs during charge/discharge *** Mn2O3 electrode exhibits high reversible capacity(233 mAh g−1 at 0.3 A g−1),superior rate capability(162 mAh g−1 retains at 3.08 A g−1)and remarkable cycling durability over 3000 cycles at a high current rate of 3.08 A g−***,the corresponding electrode reaction mechanism is studied in depth according to a series of analytical *** results suggest that rational design of the nanoporous architecture for electrode materials can effectively improve the battery performance.

关键词： Porous Mn_(2)O_(3) High-rate capability Zn-ion battery Cathode material Zn-storage mechanism

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Effect of miR-27b-3p and Nrf2 in human retinal pigment epithelial cell induced by high-glucose

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International Journal of Ophthalmology(English edition) 2023年第10期16卷 1582-1588页

作者： qiao-ling Lai Ting Xie Wei-Dong Zheng Yan Huang Department of Ophthalmology and Optometry Fujian Medical UniversityFuzhou 350004Fujian ProvinceChina The First Affiliated Hospital of Fujian Medical University Fuzhou 350004Fujian ProvinceChina

AIM:To determine whether the microRNA-27b-3p(miR-27b-3p)/NF-E2-related factor 2(Nrf2)pathway plays a role in human retinal pigment epithelial(hRPE)cell response to high glucose,how miR-27b-3p and Nrf2 expression are regulated,and whether this pathway could be specifically ***:hRPE cells were cultured in normal glucose or high glucose for 1,3,or 6d before measuring cellular proliferation rates using cell counting kit-8 and reactive oxygen species(ROS)levels using a dihydroethidium ***-27b-3p,Nrf2,NAD(P)H quinone oxidoreductase 1(NQO1)and heme oxygenase-1(HO-1)mRNA and protein levels were analyzed using reverse transcription quantitative polymerase chain reaction(RT-qPCR)and immunocytofluorescence(ICF),*** blot analyses were performed to determine nuclear and total Nrf2 protein ***2,NQO1,and HO-1 expression levels by RT-qPCR,ICF,or Western blot were further tested after miR-27b-3p overexpression or inhibitor lentiviral ***,the expression level of those target genes was analyzed after treating hRPE cells with ***:Persistent exposure to high glucose gradually suppressed hRPE Nrf2,NQO1,and HO-1 mRNA and protein levels and increased miR-27b-3p mRNA *** glucose also promoted ROS release and inhibited cellular ***2,NQO1,and HO-1 mRNA levels decreased after miR-27b-3p overexpression and,conversely,both mRNA and protein levels increased after expressing a miR-27b-3p *** treating hRPE cells exposed to high glucose with pyridoxamine,ROS levels tended to decreased,proliferation rate increased,Nrf2,NQO1,and HO-1 mRNA and protein levels were upregulated,and miR-27b-3p mRNA levels were ***:Nrf2 is a downstream target of ***,the miR-27b-3p inhibitor pyridoxamine can alleviate high glucose injury by regulating the miR-27b-3p/Nrf2 axis.

关键词： human retinal pigment epithelial cell high glucose pyridoxamine microRNA-27b-3p NF-E2-related factor 2 NAD(P)H quinone oxidoreductase 1 heme oxygenase-1

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Selectivity of guanidinium ionic liquid for capillary gas chromatography

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Chinese Chemical Letters 2010年第11期21卷 1358-1360页

作者： Kai Lu Li Zhen qiao Mei ling Qi Ruo Nong Fu Department of Chemistry School of Sciences Beijing Institute of Technology Beijing 100081 China

A guanidinium ionic liquid,N,N,N＇,N＇-tetrahexyl-N＂,N＂-dimethylguanidinium bis（trifluoromethane）sulfonylimide（THDMGNTf2）, was synthesized and used as stationary phase for capillary gas *** comparison with imidazolium ionic liquid stationary phase,the present new stationary phase exhibits quite different selectivity and behaves more like a low polar stationary *** guanidinium ionic liquid of THDMG-NTf2 exhibited better separation of Grab test mixture than imidazolium ionic liquid of 1-octyl-3-butylimidazolium bis（trifluoromethane）sulfonylimide（OBIM-NTf2）.Solvation parameter model was also used to evaluate the selectivity of ***,essential oil of Magnolia biondii Pamp was analyzed to further evaluate the selectivity of THDMG-NTf2 for a sample of complicated *** separation of the essential oil was achieved on a THDMG-NTf2 column（10 m） while using a commercial column（30 m） as *** present study shows that the guanidinium ionic liquid possesses novel chromatographic selectivity and has great potential for wide applications.

关键词： Guanidinium ionic liquids Capillary gas chromatography Stationary phase

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Hemoglobin within normal range is negatively related to hemoglobin A1c in a nondiabetic American population aged 16 years and older

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World Journal of Diabetes 2022年第3期13卷 251-259页

作者： Xiao-Fang Bai Huan Wang qiao-ling Zhao Department of Ultrasound Medicine The First Affiliated HospitalXi'an Jiaotong UniversityXi'an 710061Shannxi ProvinceChina Department of Pain Medicine The First Affiliated HospitalXi'an Jiao tong UniversityXi'an 710061Shannxi ProvinceChina

BACKGROUND Protein glycosylated hemoglobin,hemoglobin A1c(HbA1c)binds hemoglobin(Hb)in red blood cells to blood ***,the relationship between Hb and HbA1c remains *** To elucidate their relationship in a nondiabetic population aged≥16 years in the United States,using data from the 1999-2018 National Health and Nutrition Examination *** This study was based on data from 44560 adults aged≥16 years,excluding those with *** relationship was estimated using a multivariate *** also used piecewise linear regression for subgroup analysis based on age and sex stratification and analysis of the threshold effects of Hb on *** Hb and HbA1c levels were negatively correlated in the unadjusted model(β=-0.01;95%CI:-0.01,-0.01).The correlation was significantly negative when the regression model was minimally regulated and stratified by age and sex,and remained negative when the model was further regulated(more than 10%)to identify covariates with the HbA1c level influence *** subgroup analyses based on age and sex stratification,the association remained negative when the covariates were controlled.A nonlinear relationship was observed between them when the Hb levels reached the tipping point(13.2 g/dL)(adjusted odds ratio,-0.04;95%CI:-0.05,-0.03)and when the Hb levels exceeded 13.2 g/dL(adjusted odds ratio,-0.10;95%CI:-0.10,-0.09).CONCLUSION Our study shows that normal Hb levels are negatively correlated with HbA1c in nondiabetic Americans aged≥16 years.

关键词： Haemoglobin Glycosylated haemoglobin Diabetes National Health and Nutrition Examination Survey

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Follicle-stimulating hormone promotes proliferation of cultured chicken ovarian germ cells through protein kinases A and C activation

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2010年第12期11卷 952-957页

作者： Hong-yun LIU Wei-dong ZENG Ai-ling CAO Cai-qiao ZHANG Key Laboratory of Animal Epidemic Etiology and lmmunological Prevention of the Ministry of Agriculture College of Animal Sciences Zhejiang University Hangzhou 310029 China Xiaoshan Entry-Exit Inspection and Quarantine Bureau Hangzhou 311208 China

The study was conducted to investigate the effects of follicle-stimulating hormone (FSH) on embryonic chicken ovarian germ cell proliferation and its possible involvements of protein kinases A (PKA) and C (PKC) *** cells were treated with FSH alone or in the presence of forskolin (FRSK),PKA inhibitor (H89),PKC activator (PMA) or inhibitor (H7).The germ cell number was counted from *** immunocytochemistry of proliferating cell nuclear antigen (PCNA) was applied to identify the proliferating *** germ cell labeling index (LI) was determined for cell *** FSH treatment increased the germ cell number,and this stimulating effect was enhanced by FRSK or PMA,but inhibited by H89 or H7 in a dose-dependent ***,the PCNA-LI showed parallel changes with germ cell *** study suggests that FSH may stimulate proliferation of cultured chicken ovarian germ cells by activation of both the PKA and PKC signaling pathways.

关键词： Follicle-stimulating hormone Protein kinase A Protein kinase C Germ cell Proliferation

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Milk Consumption and Lactose Intolerance in Adults

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Biomedical and Environmental Sciences 2011年第5期24卷 512-517页

作者： qiao Rong HUANG ChengYu DU HuiZhang ZENG Guo LI ling YE Sheng Department of Nutrition and Food Safety Sichuan University Chengdu 610041 Sichuan China West China Second University Hospital Sichuan University Chengdu 610041 Siehuan China Tumor Hospital of Yanting County Mianyang 621600 Sichuan China

Objective To investigate relations between milk consumption and lactose intolerance （LI） in adults and to explore the effect of milk consumption on lactase *** Total of 182 subjects aged 20‐70 years were recruited and interviewed by questionnaires,and their accumulative cow＇s milk intake （AMI） was *** was evaluated by hydrogen breath test （HBT）.Results A negative correlation was found between AMI and severity of observed LI symptom （r=-0.2884;P0.05）.Binary logistic regression analysis showed a negative correlation between LI and duration and frequency of milk consumption （OR,0.317 and 0.465,respectively;both P0.05） and a positive correlation between LI and amount of milk consumed per sitting （OR,6.337;P0.05）.Conclusion LI is related to various milk consumption *** Chinese adults with LI may tolerate moderate milk consumption 160 mL.

关键词： Lactose intolerance Accumulative cow's milk intake (AMI) Milk consumption behavior

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Development of glyphosate-tolerant transgenic cotton plants harboring the G2-aroA gene

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Journal of Integrative Agriculture 2017年第3期16卷 551-558页

作者： ZHANG Xiao-bing TANG qiao-ling WANG Xu-jing WANG Zhi-xing Biotechnology Research Institute Chinese Academy of Agricultural Sciences Biology Institute Hebei Academy of Sciences

Given that glyphosate weed control is an effective strategy to reduce costs and improve economic outcomes of agricultural production in China,the development of glyphosate-resistant cotton holds great *** an Agrobacterium-mediated transformation method,a new G2-aroA gene that encodes 5-enolpyruvylshikimate-3-phosphate synthase（EPSPS）was transformed into cotton cultivar *** transgenic cotton plants were regenerated from a callus tissue culture via kanamycin *** regenerated cotton plants were obtained and allowed to flower normally to produce *** results from polymerase chain reaction（PCR）and Southern and Western blot analyses indicated that the target gene was integrated into the cotton chromosome and was expressed effectively at the protein *** glyphosate tolerance analysis showed that the transgenic cotton had a high resistance to ***,even cotton treated with 45.0 mmol L^–1 of glyphosate was able to slowly grow,bloom and *** transgenic cotton may be used for cotton breeding research of glyphosate-tolerant cotton.

关键词： cotton (Gossypium hirsutum L.) Agrobacterium-mediated method glyphosate G2-aroA genetic transformation

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