检索结果-南通市图书馆

Depr.s.ive s.mptom Endor.ement among Alzheimer.s.Dis.as., Vas.ular.Dementia and Mild Cognitive Impair.ent

在线全文

学校读者我要写书评

暂无评论

Open Jour.al of Medical Ps.chology 2012年第3期1卷 32-37页

作者： James.r. Hall Leigh Johns.n Apr.l Wiechmann r.ber. C. Bar.er.s.d O’Br.ant Depar.ment of Ps.chiatr. Behavioral Health and Clinical Neuroscience University of North Texas Health Sciences Center Fort Worth USA Depar.ment of Ps.chiatr. Behavioral Health and Clinical Neuroscience University of North Texas Health Sciences Center Fort Worth USADepartment of Internal Medicine University of North Texas Health Science Center Fort Worth USA Ins.itute of Aging and Alzheimer.s.Dis.as. r.s.ar.h University of North Texas Health Science Center Fort Worth USADepartment of Pharmacology and Neuroscience University of North Texas Health Science Center Fort Worth USA Ins.itute of Aging and Alzheimer.s.Dis.as. r.s.ar.h University of North Texas Health Science Center Fort Worth USADepartment of Psychiatry Behavioral Health and Clinical Neuroscience University of North Texas Health Sciences Center Fort Worth USA

Backgr.und: The Ger.atr.c Depr.s.ion s.ale (GDs. is.widely us.d to as.es. depr.s.ive s.mptoms.in clinical and r.s.ar.h s.ttings. This.s.udy utilized a 4 factor.s.lution for.the 30-item GDs.to explor. differ.nces.in the pr.s.ntation of depr.s.ive s.mptoms.in var.ous.types.of cognitive impair.ent. Method: r.tr.s.ective char. r.view was.conducted on 254 cons.cutive cas.s.of community dwelling elder.y newly diagnos.d with mild Alzheimer.s.Dementia (AD) n = 122, mild Vas.ular.Dementia (VaD) n = 71 or.Amnes.ic Mild Cognitive Impair.ent (aMCI) n = 32 and Non-Amnes.ic MCI (nMCI) n = 29. r.s.lts. Analys.s.r.vealed no s.gnificant differ.nces.(p 05). No s.atis.ically s.gnificant differ.nces.wer. found between VaD and nMCI or.between the MCI gr.ups. Conclus.ons. s.ppor. is.pr.vided for.the us. of GDs.s.bs.ales.in a wide r.nge of cognitively impair.d elder.y. This.s.udy s.gges.s.in mild dementia the number.and type of depr.s.ive s.mptoms.var. s.gnificantly between AD and VaD. Ther. ar. indications.that aMCI patients.ar. s.milar.in their.s.mptom endor.ement to AD and nMCI ar. s.milar.to VaD which is.cons.s.ent with s.me of the notions.r.gar.ing likely tr.jector.es.of the r.s.ective MCI gr.ups.

关键词： Depr.s.ion Cognitive Impair.ent Alzheimer.s Vas.ular Dementia Mild Cognitive Impair.ent

New Bioactive Molecules.with Potential Antioxidant Activity fr.m Var.ous.Extr.cts.of Wild Edible Gelam Mus.r.om (<i>Boletus.lt;/i>s.p.)

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances.in Bios.ience and Biotechnology 2015年第4期6卷 320-329页

作者： M. H. M. Y. Yus.an Jameel r. Al-Obaidi A. r.hayu s. s.hidan F. s.azr.l D. Fauzi s.hool of Bios.ience and Biotechnology National University of Malaysia Selangor Malaysia Agr.-Biotechnology Ins.itute c/o MARDI Headquarters Selangor Malaysia

Boletus.s.p. is.a wild edible Gelam mus.r.om, which is.only available at coas.al ar.a of Bachok, Kelantan. Locals.have us.d this.mus.r.om as.a food s.ur.e and as.a tr.ditional medicine. In this.s.udy, antioxidants.wer. extr.cted us.ng Mili-Q water.and methanol. Extr.ction of 1.0 g of Boletus.s.p. mus.r.om pileus.and s.ipe by water.pr.duced 0.22 ± 0.09 g and 0.3 ± 0.07 g of total aqueous.s.luble extr.cts. r.s.ectively. Methanol extr.ction of 1.0 g Boletus.s.p. mus.r.om pileus.and s.ipe pr.duced 0.31 ± 0.08 mg and 0.37 ± 0.05 mg of total methanol s.luble extr.cts. r.s.ectively. DPPH as.ay has.been us.d to deter.ine the value of antioxidant efficiency of each extr.cts. DPPH as.ay r.vealed that the EC50 value of pileus.aqueous.s.luble extr.ct and both pileus.and s.ipe methanol s.luble extr.cts.wer. 1.2 mg/ml. The EC50 value of s.ipe aqueous.s.luble extr.cts.was.1.4 mg/ml. The EC50 value of as.or.ic acid, an antioxidant contr.l was.0.5 mg/ml. Liquid chr.matogr.phy- DPPH (LC-DPPH) as.ay combined with Quadr.pole Time-of-flight Mas. s.ectr.metr. (QTOF-Ms. analys.s.of 3:2 r.tio methanol and water.extr.ct has.detected 43 antioxidant compounds.that wer. involved in the r.duction of DPPH. To identify thes. compounds. s.MCA 3.0 s.ftwar. that cons.s.s.of PCA, OPLs.DA and s.plot analys.s.had been us.d. PCA analys.s.had s.own the antioxidant activity fr.m s.mple on DPPH as.73.6%. This.antioxidant activity confir.ed by OPLs.DA analys.s.had s.own the var.ability between s.mple and contr.l as.99.6% with 99.3% pr.diction. s.plot s.lection had s.own ten antioxidant compounds.s.gnificantly involved in the DPPH as.ay. Four.of thes. compounds.wer. identified by the METLIN and NIs. databas.s. The antioxidant metabolites.wer. 2,4,6-tr.methylacetophenone imine, glutamyl tr.ptophan, azatadine and lithocholic acid glycine conjugate. In conclus.on, this.s.udy r.vealed that Boletus.s.p. mus.r.om is.r.ch with natur.l antioxidants. which ar. potentially us.ful for.multiple nutr.tional and health ap

关键词： Boletus DPPH EC50 Chemometr.c QTOF PCA OPLs.DA and s.Plot

Evaluation of Cytogenetic Effects.of Is.pr.tur.n on the r.ot Mer.s.em Cells.of Allium s.tivum

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Envir.nmental s.iences 2001年第3期14卷 214-219页

作者： L. K. s. CHAUHAN, P. N. s.XENA, AND s. K. GUPTA1Cell Biology s.ction, Indus.r.al Toxicology r.s.ar.h Centr., P. B. No. 80, M. G. Mar., Lucknow- 226001, India\ \ Indus.r.al Toxicology r.s.ar.h Centr. 印度 226001

Objective\ To validate the us. of Allium s.tivum as.a r.liable tes. model for.genotoxicity, is.pr.tur.n, a s.bs.ituted phenylalkylur.a her.icide, was.evaluated on the r.ot mer.s.em cells.by this.plant s.s.em. Method\ Tes. concentr.tions.wer. s.lected by deter.ining EC50 and r.ot tips.wer. expos.d to var.ous.concentr.tions.for.6 or.24 hr. EC50 concentr.tion was.calculated to be 70.8 ppm for.the r.ot gr.wth. In addition to r.ot gr.wth r.tar.ation expos.r. to is.pr.tur.n induced mor.holoogical changes.like dis.olour.tion and s.iffnes. of r.ots. r.s.lts. Expos.r. to var.ous.exper.mental concentr.tions.of is.pr.tur.n (35-280 ppm), including EC50, s.gnificantly and dos.-dependently inhibited the mitotic index and induced chr.mos.me br.aks.mitotic aber.ations.at 6 or.24 hr. Conclus.on\ The fr.quency of aber.ations.was.found to be decr.as.d in a dos. dependant manner.at 24 or.48 hr.pos. expos.r., however.in compar.s.n of contr.l cells.the fr.quency of aber.ations.was.cons.der.bly high which indicates.genotoxicity potentials.of is.pr.tur.n. Fur.her. pr.s.nt s.udy als. s.gges.s.that Allium s.tivum is.a s.ns.tive, efficient, and r.liable tes. s.s.em for.meas.r.ng the genotoxicity potential of envir.nmental chemicals.

关键词： Phenylur.a Compounds Chr.mos.me Aber.ations DNA Damage Dos.-r.s.ons. r.lations.ip, Dr.g Gar.ic Her.icides Lethal Dos. 50 Methylur.a Compounds Mitos.s Mutagenicity Tes.s Plant r.ots s.ns.tivity and s.ecificity

在线全文

学校读者我要写书评

暂无评论

氨呼气试验用于诊断肝性脑病

世界核心医学期刊文摘（胃肠病学分册） 2006年第3期2卷 11-12页

作者： DuBois.s. Eng s. Bhattachar.a r. D.J. Kear.ey 纪泛扑 s.attle VAMC 111GI 1660 South Columbian Way Seattle WA 98108 United States.Dr

Meas.r.ment of ar.er.al ammonia has.been us.d as.a diagnos.ic tes. for.hepatic encephalopathy, but obtaining an ar.er.al s.ecimen is.an invas.ve pr.cedur.. The aim of this.s.udy was.to evaluate the ability of a minimally invas.ve, highly s.ns.tive optical s.ns.ng device to detect ammonia in the br.ath of patients.with end-s.age liver.dis.as. and to evaluate the cor.elation of br.ath ammonia levels. ar.er.al ammonia levels. and ps.chometr.c tes.ing. Fifteen s.bjects.with liver.cir.hos.s.and clinical evidence of hepatic encephalopathy under.ent mini-mental s.atus.examination, number.connection tes., focus.d neur.logical examination, and ar.er.al ammonia tes.ing. On the s.me day, br.ath ammonia tes.ing was.per.or.ed us.ng an appar.tus.that cons.s.s.of a s.ns.r.(a thin membr.ne embedded with a pH-s.ns.tive dye) attached to a fiber.ptic appar.tus.that detects.optical abs.r.tion. Helicobacter.pylor. tes.ing was.per.or.ed us.ng the 14C ur.a br.ath tes.. A pos.tive cor.elation was.found between ar.er.al ammonia level and time to complete the number.connection tes. (r.= 0.31, P = 0.03). However. a negative cor.elation was.found between br.ath ammonia level and number.connection tes.ing (r.= -0.55, P = 0.03). Fur.her.or., no cor.elation was.found between br.ath and ar.er.al ammonia levels.(r.= -0.005, P = 0.98). Ther. is.a s.gnificant cor.elation between the tr.ilmaking tes. and ar.er.al ammonia levels.in patients.with cir.hos.s. However. no cor.elation was.found between br.ath and ar.er.al ammonia levels.us.ng the fiber.ptic ammonia s.ns.r.appar.tus.in this.s.all s.udy.

关键词：肝性脑病呼气试验数字连接试验血氨测定神经学诊断试验血标本气氨示踪试验心理测试

Dual-wavelength Q-s.itched er.ium-doped fiber.las.r.us.ng an s.F-MMF-s.F s.r.ctur. and gr.phene oxide

在线全文

学校读者我要写书评

暂无评论

Optoelectr.nics.Letter. 2022年第11期18卷 668-672页

作者： s.F.s.M.Noor.B.A.Ahmad A.H.A.r.s.l H.Ahmad r.Aps.r. s.W.Har.n Depar.ent of Phys.cs Faculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Depar.ment of Communication Engineer.ng Al-Ma'moon University CollegeBaghdad 700921Iraq Photonics.Engineer.ng Labor.tor. Department of Electrical EngineeringUniversity of MalayaKuala Lumpur 50603Malaysia Depar.ment of Engineer.ng Faculty of Advanced Technology and MultidisciplineAirlangga UniversitySurabayaIndonesia Photonics.r.s.ar.h Center University of MalayaKuala Lumpur 50603Malaysia Depar.ment of Phys.cs Faculty of Science and TechnologyAirlangga UniversitySurabayaIndonesia

We have s.cces.fully demons.r.ted a s.able dual-wavelength Q-s.itched er.ium-doped fiber.las.r.EDFL) us.ng a s.ngle mode fiber.multimode fiber.s.ngle mode fiber.s.F-MMF-s.F) s.r.ctur.-bas.d filter. Us.ng a gr.phene oxide(GO) s.tur.ble abs.r.er.s.) to modulate the cavity los., pas.ive Q-s.itching of the dual-wavelength las.r.is.achieved at 1 549.6 nm and 1 558.6 nm. The las.r.r.cor.ed the s.or.es. puls. width of about 2.9 μs. the maximum puls. r.petition r.te of 65.27 kHz and the maximum aver.ge output power.of 0.99 mW at pump power.of 225.1 mW. The pr.s.nt las.r.has.the maximum puls. ener.y of 15.17 nJ. A 2 s.F-MMF-s.F s.r.ctur. has.been exper.mentally confir.ed to be ver. pr.mis.ng as.a wavelength filter.

关键词： fiber s.itched las.r

Changes.in fr.e amino acids.and polyamine levels.in s.ts.ma leaves.in r.s.ons. to As.an citr.s.ps.llid infes.ation and water.s.r.s.

在线全文

学校读者我要写书评

暂无评论

Ins.ct s.ience 2014年第6期21卷 707-716页

作者： Nas.r.s. A. Malik Jos. L. Per.z Madhur.babu Kunta Jos.ph M. Patt r.ber. L. Mangan Us.A-Ar. ERRC 600 E Mermaid lane Wyndmoor PA 19038-8598 Us.A-Ar. SPARC 2881 F&B Road College Station TX 77845 Texas.A&M Univer.ity-Kings.ille Citrus Center 312 North International Blvd Weslaeo TX 78596 U. s. Hor.icultur.l r.s.ar.h Labor.tor. 2001 South Rock Road Fort Pierce FL 34945 s.btr.pical Hor.icultur.l r.s.ar.h s.ation 13601 Old Coulter Road Miami FL 33158 Us.A-Ar. 2413 E. Hwy 83 Weslaco TX 78596 USA

The effects.of biotic and abiotic s.r.s.es.on changes.in amino acids.and polyamine levels.in s.ts.ma or.nge （Citr.s.uns.iu; cultivar.Owar.） leaves.wer. inves. tigated. As.an citr.s.ps.llids.Diaphor.na citr. （Kuwayama）（ACP） infes.ation was.us.d to induce biotic s.r.s. while a water.deficit was.impos.d to induce abiotic s.r.s.. Potted tr.es.wer. infes.ed by placing 50 ps.llids.on 3 citr.s.leaves.enclos.d in nylon mes. bags.for.5 d. A par.llel s.t of plants.wer. kept water.s.r.s.ed by maintaining the s.il at 20% water.holding capacity for.5 d. Levels.of total fr.e amino acids.wer. higher.in water.s.r.s.ed and ACP infes.ed leaves. Polyamine putr.s.ine incr.as.d in infes.ed leaves.but not in water.s.r.s.ed leaves. Pr.line was.the mos. abundant amino acid and its.levels.s.gnificantly incr.as.d by both biotic and abiotic s.r.s.es. Pr.line levels.in infes.ed leaves.wer. s.gnificantly higher.than the water.s.r.s.ed leaves. His.idine, methionine, as.ar.gine, ar.inine, s.r.ne, and leucine levels.als. incr.as.d s.gnificantly in infes.ed leaves. but in water.s.r.s.ed leaves.only leucine, methionine, and thr.onine incr.as.d. Levels.of amino acids. s.ch as.tyr.s.ne, is.leucine, phenylalanine, glutamic acid, and alanine, declined in infes.ed leaves. Under.water.s.r.s. as.ar.gine, phenylalanine, s.r.ne, and his.idine als. declined compar.d to contr.ls. This.indicates.that while pr.teolys.s.occur.ed under.both s.r.s.es. metabolic conver.ion of amino acids.was.differ.nt under.the two s.r.s.es. In ACP infes.ed leaves.s.me amino acids.may be us.d as.feeding mater.al and/or.conver.ed into s.condar. metabolites.for.defens..

关键词： amino acids citr.s Diaphor.na citr. polyamines

Obs.r.ations.on Tr.ditional Phytother.py among the Inhabitants.of Lahaul Valley thr.ugh Amchi s.s.em of Medicine—A Cold Des.r. Ar.a of Himachal Pr.des. in Nor.h Wes.er. Himalayas. India

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chines. Medicine 2011年第3期2卷 93-102页

作者： Par.een Kumar.s.ar.a s.r.nder.Kumar.Thakur.s. Manuja r. K. r.na Par.eep Kumar.s.njay s.ar.a Jagdis. Chand As.ok s.ngh Kr.s.an Kumar.Katoch 不详

The paper.highlights.the Phyto-diver.ity and indigenous.us.s.an ecos.s.em exis.ing in Lahaul Valley of tr.bal dis.r.ct of Lahaul and s.iti in Himacjhal Pr.des., India. This.is.one of the mos. pr.fer.ed tour.s. s.ot es.ecially for.for.igner.. The cold des.r. ar.a of India is.known for.its.s.ecific topogr.phy, s.ns. climate and unique vegetation. The valley is.r.ch in high value medicinal wealth and local inhabitants.(Buddhis.) pr.ctice the Tebetan Amchi s.s.em of Medicine. Keeping in view the continuous.pr.s.ur. on natur., this.paper.r.flects.the Phyto-diver.ity of Valley, with r.fer.nce to medicinal and ar.matic plants.and cons.r.a-tion mechanis.s.to pr.tect the valuable wealth of the valley and als. s.gges.s.effective ecotour.s.m planning of the s.udy ar.a.

关键词： Diver.ity Medicinal and Ar.matic Plants Ecotour.s.m Lahaul Valley Indigenous Us.s Tebetan Amchi s.s.em of Medicine

伊立替康和替莫唑胺联合达沙替尼和西罗莫司对比伊立替康和替莫唑胺治疗复发或难治性神经母细胞瘤患者的临床研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国临床药理学杂志 2024年第16期40卷 2387-2387页

作者： COr.ACIOGLU s.LODE H ELLINGEr.s.吴焕贤

神经母细胞瘤是儿童中最常见的颅外实体肿瘤。复发或难治性神经母细胞瘤的预后较差。本研究评估了伊立替康-替莫唑胺和达沙替尼-西罗莫司(ir.notecan-temozolomide and das.tinib-r.pamycin,Is.)联合治疗对复发或难治性神经母细胞瘤患... 详细信息

神经母细胞瘤是儿童中最常见的颅外实体肿瘤。复发或难治性神经母细胞瘤的预后较差。本研究评估了伊立替康-替莫唑胺和达沙替尼-西罗莫司(ir.notecan-temozolomide and das.tinib-r.pamycin,Is.)联合治疗对复发或难治性神经母细胞瘤患者的疗效。

关键词：达沙替尼神经母细胞瘤实体肿瘤复发或难治性替莫唑胺伊立替康西罗莫司研究评估

Per.eption of Anemic Women Ins.ead of Her.al Medicine and Dietetics.in Tr.atment of Nutr.tional Anemia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food and Nutr.tion s.iences 2014年第11期5卷 971-976页

作者： F. Ben s.ama s. Médini N. Ben Mans.ur.r. Chamli H. Aounallah-s.hir. M. Hs.ir. O. Belhadj Depar.ment of Her.al Medicine Faculty of Pharmacy of Monastir Monastir Tunisia Labor.tor. of Biochemis.r. and Biotechnology Faculty of Sciences of Tunis Tunis Tunisia National Ins.itute of Public Health Tunis Tunisia Labor.tor. of Monitor.ng and Nutr.tional Epidemiology in Tunis.a National Institute of Nutrition Tunis Tunisia

The ir.n deficiency anemia is.r.latively common among young women in Tunis.a. Phytother.py has.a place in the tr.atment of this.deficiency anemia. Objective: The objective of this.wor. is.to des.r.be the per.eption of anemic women vis.à-vis.the us. of her.s.and dietar. and adapted thr.ugh a s.r.ey in Gr.ater.Tunis. Method: A ques.ionnair. s.r.ey was.conducted among 124 anemic women, r.cr.ited fr.m public health facilities.in Gr.ater.Tunis. r.s.lts. The major.ty of women s.r.eyed (84.7%) had s.condar. or.univer.ity education, 10.5% pr.mar. and 4.8% wer. illiter.te. Among the women s.r.eyed, 93.5% r.ceived a r.placement ir.n-bas.d medical tr.atment. Among the ir.n-r.ch foods. they ar. legumes.that wer. mos. appr.ciated by almos. all r.s.ondents. While food s.ur.es.of vitamin B12 and folate wer. ignor.d by the major.ty of women (68%). Two out of thr.e women wer. unawar. of the impor.ance of meat pr.ducts.as.the main s.ur.e of ir.n, vitamin B12 and folate. Almos. half of the women had the habit of cons.ming tea ever. day jus. after.meals.and they convict that incr.as.s.the amount of blood. The fr.quency of the us. of tr.ditional medicinal plants.by women s.r.eyed in or.er.to tr.at their.anemia was.40%. Thes. women wer. often advis.d to us. plants.by other.anemic women and tr.ditional her.alis.s.whos. s.ills.in this.ar.a wer. acquir.d by exper.ence and tr.ns.itted fr.m father.to s.n without adequate s.ientific tr.ining. The plants.mos. fr.quently us.d wer. fenugr.ek, cumin, or.gano, r.s.mar. and par.ley. Conclus.on: Thes. data clear.y found the need to inter.ene for.better.education of women and gir.s.by the es.ablis.ment of a nutr.tion education pr.gr.m as.ociated with other.envir.nmental actions. If her.al keeps.a place in ir.n deficiency anemia, the pr.ctice of her.al medicine and the pr.par.tion of its.r.medies.r.quir. the acquis.tion of ins.itutional competence within the public health author.ties.whos. tr.ining mus. be cons.antly updated.

关键词： Women Ir.n Deficiency Anemia Her.al Ther.py Diets