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Ge nanoparticles uniformly immobilized on 3D interconnected porous graphene frameworks as anodes for high-performance lithium-ion batteries

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Journal of Energy Chemistry 2022年第6期31卷 161-173,I0005页

作者： Yao Chen Yuming Zou Xiaoping Shen Jingxia Qiu Jiabiao Lian Jinrui pu Sheng Li fei-Hu Du Shang-Qi Li Zhenyuan Ji Aihua Yuan School of Material Science and Engineering School of Chemistry and Chemical EngineeringInstitute for Energy ResearchJiangsu UniversityZhenjiang 212013JiangsuChina School of Environmental and Chemical Engineering Shanghai UniversityShanghai 200444China School of Environmental&Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003JiangsuChina

Germanium(Ge), an alloy-type anode material for lithium-ion batteries(LIBs), possesses many advantages such as high theoretical capacity and decent electrical conductivity. Nevertheless, its application is restricted by tremendous volume variation and tardy reaction kinetic during discharge/charge *** this paper, the Ge/3DPG composites with Ge nanoparticles uniformly dispersed in 3D interconnected porous graphene(3DPG) skeleton are successfully prepared using a template-assisted in-situ reduction method. The unique 3D interconnected porous graphene can not only enhance the electronic conductivity and reaction kinetics of the materials, but also provide sufficient buffer space to effectively mitigate the volume expansion during cycling and strengthen the structural integrity. Moreover, the small-sized Ge nanoparticles in close conjunction with the 3D graphene can boost the surface-controlled reaction of the electrode, which contributes to a fast charge–discharge rate capability. The Ge/3DPG composite with optimized Ge/graphene mass ratio delivers high reversible specific capacity(1102 mAh g^(-1) after 100 cycles at 0.2 C), outstanding rate capability(494 mAh g^(-1) at 5 C), and admirable cycling stability(85.3% of capacity retention after 250 cycles at 0.5 C). This work provides a significant inspiration for the design and fabrication of advanced Ge-based anode materials for next-generation highperformance LIBs.

关键词： Germanium nanoparticles 3D porous graphene Composites Anode materials Lithium storage performance

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Physics-data-driven intelligent optimization for large-aperture metalenses

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Opto-Electronic Advances 2023年第11期6卷 5-15页

作者： Yingli Ha Yu Luo Mingbo pu fei Zhang Qiong He Jinjin Jin Mingfeng Xu Yinghui Guo Xiaogang Li Xiong Li Xiaoliang Ma Xiangang Luo National Key Laboratory of Optical Field Manipulation Science and Technology Chinese Academy of SciencesChengdu 610209China State Key Laboratory of Optical Technologies on Nano-Fabrication and Micro-Engineering Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209China Research Center on Vector Optical Fields Institute of Optics and ElectronicsChinese Academy of SciencesChengdu 610209China School of Optoelectronics University of Chinese Academy of SciencesBeijing 100049China Tianfu Xinglong Lake Laboratory Chengdu 610299China

Metalenses have gained significant attention and have been widely utilized in optical systems for focusing and imaging,owing to their lightweight,high-integration,and exceptional-flexibility *** design methods neglect the coupling effect between adjacent meta-atoms,thus harming the practical performance of *** existing physical/data-driven optimization algorithms can solve the above problems,but bring significant time costs or require a large number of ***,we propose a physics-data-driven method employing an“intelligent optimizer”that enables us to adaptively modify the sizes of the meta-atom according to the sizes of its surrounding *** implementation of such a scheme effectively mitigates the undesired impact of local lattice coupling,and the proposed network model works well on thousands of data-sets with a validation loss of 3×10^(−3).Based on the“intelligent optimizer”,a 1-cm-diameter metalens is designed within 3 hours,and the experimental results show that the 1-mm-diameter metalens has a relative focusing efficiency of 93.4%(compared to the ideal focusing efficiency)and a Strehl ratio of *** to previous inverse design method,our method significantly boosts designing efficiency with five orders of magnitude reduction in *** generally,it may set a new paradigm for devising large-aperture meta-devices.

关键词： intelligence method physics-data-driven method inverse design large-aperture metalenses

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复元醒脑汤对MCAO模型大鼠血脑屏障的保护作用及机制研究

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时珍国医国药 2024年第4期35卷 783-787页

作者：孙玉婷张文蒲玉婷吴霖光缙陈采玉徐湘茹费月蓉方邦江上海中医药大学附属龙华医院上海200032 上海中医药大学急危重症研究所上海200032

目的探究复元醒脑汤对急性缺血性脑梗死模型大鼠血脑屏障的影响及机制研究。方法取40只SD大鼠随机分为假手术组、模型组、复元醒脑汤组和尼莫地平组,除假手术组外,其余各组建立大鼠大脑中动脉栓塞制备缺血性脑梗死模型。假手术组和模型... 详细信息

目的探究复元醒脑汤对急性缺血性脑梗死模型大鼠血脑屏障的影响及机制研究。方法取40只SD大鼠随机分为假手术组、模型组、复元醒脑汤组和尼莫地平组,除假手术组外,其余各组建立大鼠大脑中动脉栓塞制备缺血性脑梗死模型。假手术组和模型组给予0.9%氯化钠溶液、复元醒脑汤组和尼莫地平组给予相应的等效剂量药物,每日灌胃2次,连续灌胃3d。采用Bederson神经功能评分;HE染色观察各组大鼠脑组织病理变化;采用IHC观察ZO-1和Claudin-5的表达;Western blot检测大鼠脑组织MMP-2、MMP-9、ZO-1和Claudin-5的蛋白表达情况;RT-qPCR检测大鼠脑组织MMP-2、MMP-9、ZO-1和Claudin-5基因表达水平。结果与假手术组比较,模型组大鼠神经功能缺损评分升高;与假手术组相比,模型组大鼠脑组织MMP-2和MMP-9蛋白和mRNA表达升高(P<0.05,P<0.01),ZO-1和Claudin-5蛋白mRNA表达降低(P<0.05,P<0.01);与模型组相比,复元醒脑汤组的大鼠脑组织缺血半暗带MMP-2和MMP-9蛋白mRNA表达显著降低(P<0.05,P<0.01);ZO-1和Claudin-5蛋白mRNA表达显著升高(P<0.05,P<0.01)。结论复元醒脑汤保护血脑屏障通透性,可能与抑制MMP-2和MMP-9的表达,抑制紧密连接蛋白中ZO-1和claudin-5降解及丢失,从而发挥保护血脑屏障结构功能的作用。

关键词：复元醒脑汤脑梗死血脑屏障金属基质蛋白酶紧密连接蛋白

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基于AI图像分析的铸造原砂粒度粒形检测法

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铸造 2024年第4期73卷 520-526页

作者：李贝贝郭树人曹华堂刘鑫旺董选普张宇辉钟飞升吴执成华中科技大学材料科学与工程学院材料成形与模具技术全国重点实验室湖北武汉430074 辽宁联信铸砂投资集团有限公司辽宁沈阳110000

铸造原砂的粒形和粒度分布是原砂生产和使用过程中的重要衡量指标。针对筛分法存在的测量效率和测量误差问题,本文提出一种基于人工智能(Artificial Intelligence:AI)图像分析的铸造原砂粒度粒形测试方法,即采用工业相机采集原砂图像,通... 详细信息

铸造原砂的粒形和粒度分布是原砂生产和使用过程中的重要衡量指标。针对筛分法存在的测量效率和测量误差问题,本文提出一种基于人工智能(Artificial Intelligence:AI)图像分析的铸造原砂粒度粒形测试方法,即采用工业相机采集原砂图像,通过AI图像处理技术对图像进行实例分割,然后对图像进行特征提取,统计出原砂的粒度分布和粒形分布。研究结果表明:基于AI技术的BlendMask实例分割模型能有效地分离粘连砂粒;采用圆形度、形状因子和方形度三个特征参数对原砂粒形进行K-means聚类,能够准确分析砂粒的粒形特征;采用等效椭圆法、面积占比等效质量占比法,可准确测得烘焙砂、烘干砂和宝珠砂三种铸造原砂的粒度分布,满足行业精度要求。

关键词：铸造原砂粒度分布粒形图像法实例分割深度学习

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火力发电企业集中供冷站建设

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节能 2024年第5期43卷 111-113页

作者：邓毅琨普飞高明刘双臣赵虎军段丽国能开远发电有限公司云南开远661601 国能龙源蓝天节能技术有限公司北京100039

西南某火电厂通过调研周边食品加工企业的冷库用冷需求提出集中供冷方案。将制冷装置的压缩机和其他辅助设备集中放置于厂内独立的专用机房,建设集中供冷站,利用间接制冷循环系统,通过载冷剂将冷负荷送至分散的各个冷用户。研究表明,集... 详细信息

西南某火电厂通过调研周边食品加工企业的冷库用冷需求提出集中供冷方案。将制冷装置的压缩机和其他辅助设备集中放置于厂内独立的专用机房,建设集中供冷站,利用间接制冷循环系统,通过载冷剂将冷负荷送至分散的各个冷用户。研究表明,集中供冷站可以实现自动控制、远程监控功能,具有厂用电成本优势,减少了用户设备投资及维护成本的吸引力。

关键词：火电厂集中供冷站间接制冷载冷剂

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Prevalence and incidence of heart failure among community in China during a three-year follow-up

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Journal of Geriatric Cardiology 2023年第4期20卷 284-292页

作者： Lu FU Jun-Rong JIANG Wei-Dong LIN Hui-Yi LIU Shu-Yu JIN Xing-Dong YE Yan-Lin CHEN Si-Jia pu yang LIU Shang-fei HE Shu-Lin WU Hai DENG Yu-Mei XUE Department of Cardiology Guangdong Cardiovascular InstituteGuangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhouChina The Second School of Clinical Medicine Southern Medical UniversityGuangzhouChina School of Medicine South China University of TechnologyGuangzhouChina Department of Cardiology the First Affiliated Hospital of Guangzhou Medical UniversityGuangzhouChina Guangdong Provincial Key Laboratory of Clinical Pharmacology Research Center of Medical SciencesGuangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhouChina Qinghai Province Cardio Cerebrovascular Disease Specialist Hospital XiningChina

BACKGROUND Epidemiological surveys on heart failure(HF)in Chinese community are relatively *** study aimed to estimate the prevalence and incidence of HF among community residents in southern *** Baseline data of this prospective study was collected from 2015 to 2017 among 12,013 permanent residents aged≥35years in Guangzhou,*** same survey process was carried out for individuals aged≥65 years after a three-year *** The overall prevalence of HF in community residents aged≥35 years was 1.06%.Male had significantly higher risk of HF prevalence[odds ratio(OR)=1.50,P=0.027].The gender-adjusted risk of HF was 1.48 times higher per 10 years *** prevalence was statistically associated with atrial fibrillation,valvular heart disease,hypertension and chronic obstructive pulmonary disease after adjusting for age and gender(OR=8.30,5.17,1.11,2.28,respectively;all P<0.05).HF incidence in individuals aged≥65 years were 847 per 100,000 *** atrial fibrillation,valvular heart disease,and diabetes mellitus were risk factors for HF incidence for individuals aged≥65 years adjusting for age and gender(OR=5.05,3.99,2.11,respectively;all P<0.05).Besides,residents with new-onset atrial fibrillation and myocardial infarction were at significantly higher risk of progression to HF(OR=14.41,8.54,respectively;all P<0.05).CONCLUSIONS Both pre-existing and new-onset cardiovascular diseases were associated with HF incidence in southern *** of related cardiovascular diseases may be helpful to reduce the incidence of HF.

关键词： prevalence cardiovascular incidence

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Natural variation of main biochemical components,morphological and yield traits among a panel of 87 tea [Camellia sinensis(L.) O. Kuntze] cultivars

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Horticultural Plant Journal 2023年第3期9卷 563-576页

作者： Fawad Zaman EZhang Li Xia Xielong Deng Muhammad Ilyas Ahmad Ali fei Guo pu Wang Mingle Wang Yu Wang Dejiang Ni Hua Zhao Key Laboratory of Horticultural Plant Biology of Ministry of Education Huazhong Agricultural UniversityWuhanHubei 430070China College of Horticulture and Forestry Sciences Huazhong Agricultural UniversityWuhanHubei 430070China College of Plant Science and Technology Huazhong Agricultural UniversityWuhanHubei 430070China

Many attentions have been previously focused to identify the multiple biochemical components related to tea quality and health benefits,however, the natural variation of biochemical components present in tea germplasm has not been adequately evaluated. In this study, the main biochemical components, leaf morphological and yield characteristics were evaluated for four rounds of tea leaves in a panel of 87 elite tea cultivars suitable for black, green, or oolong tea. Significant variations were observed among the tea cultivars, as well as seasonal differences in the levels of the free amino acid(FAA), caffeine(CAF), tea polyphenols(TP), water extract(WE) and TP to FAA ratio(TP/FAA). Results showed that the average levels of FAA showed a seasonal change, with the highest level of 4.0% in the 1st spring tea in the cultivars suitable for green tea and the lowest of 3.2% in summer tea in the cultivars suitable for black tea. The average CAF content was highest 3.2% in the cultivars suitable for oolong tea in the 1st spring and the lowest 2.5% in the cultivars suitable for green tea in summer. Limited seasonal and varietal variations were noticed in the average levels of WE among the three categories of tea. In addition, significant natural variation of the morphological characteristics, bud length varying from 2.5 cm to 8.7 cm, bud density from 190.3 buds · m-2to 1 730.3 buds · m-2, mature leaves biomass from 128.4 kg · hm-2to 2 888.4 kg · hm-2, and yield component traits of 100 buds(one bud with two leaves) dry weight from 3.7 g to37.7 g, tea yield/round from 444.6 kg · hm-2to 905.3 kg · hm-2, were observed. The aim of our evaluation was not only to identify the advantages of seasonal and clonal variations but also to provide a new viewpoint for their further application. Representative accessions were selected from the germplasm to promote the establishment of an inherent biochemical constituent expressing the quality of black, green, and oolong tea. The findings might

关键词： Camellia sinensis Biochemical components Germplasm Natural variation Morphology Yield

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经皮与Wiltse入路椎弓根钉置钉治疗无神经损伤胸腰椎骨折的临床疗效比较

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国际外科学杂志 2024年第3期51卷 159-165,F0003页

作者：陈萌萌贾璞陈浩包利侍管冯飞张双江唐海首都医科大学附属北京友谊医院骨科北京100050

目的比较经皮与Wiltse入路2种微创椎弓根钉置入方式治疗无神经损伤单节段胸腰椎骨折的有效性及安全性。方法回顾性分析2020年1月—2022年6月首都医科大学附属北京友谊医院收治的因单节段胸腰椎骨折行单纯微创椎弓根钉内固定的80例患者... 详细信息

目的比较经皮与Wiltse入路2种微创椎弓根钉置入方式治疗无神经损伤单节段胸腰椎骨折的有效性及安全性。方法回顾性分析2020年1月—2022年6月首都医科大学附属北京友谊医院收治的因单节段胸腰椎骨折行单纯微创椎弓根钉内固定的80例患者的临床数据,其中男性46例,女性34例,年龄27~60岁,平均(45.93±7.91)岁。根据手术方式不同分为经皮椎弓根钉内固定组(n=44)和Wiltse入路椎弓根钉组(Wiltse组,n=36)。比较两组患者手术时间、术中显性出血量、围手术期隐性失血量、总失血量、术中透视次数、切口总长度、术后住院时间、术后下地时间。分别在术前及术后3 d、6个月、1年记录并比较两组患者的视觉模拟评分(VAS)、Oswestry功能障碍指数(ODI)、椎体前缘高度比例、伤椎椎体终板角。采用术后CT评估椎弓根钉的置钉准确率及关节突关节侵扰率。观察患者围手术期相关的并发症。正态分布的计量资料以均数±标准差(x±s)表示,组间比较采用t检验;计数资料以例(%)表示,组间比较采用χ^(2)检验。结果所有患者均随访至少12个月。在术中显性失血量、术后住院时间、术后下地时间、术后VAS评分和ODI评分、术后第3天伤椎椎体高度比例、术后3 d伤椎终板角、椎弓根置钉准确率、围手术期并发症方面差异无统计学意义(P>0.05)。经皮椎弓根内固定组的手术时间、隐性失血量、总出血量、术中透视次数、关节突关节侵占率显著高于Wiltse入路组(P<0.05)。经皮椎弓根内固定组在术后6个月及1年伤椎椎体前缘高度比例显著低于Wiltse组;经皮椎弓根内固定组在术后6个月及1年伤椎终板角显著高于Wiltse组(P<0.05)。结论经皮与Wiltse入路椎弓根置钉对于无神经损伤的胸腰椎骨折均是安全有效的微创手术方式。Wiltse入路置钉能够有效减少透视次数,减少围手术期隐性失血,减少对关节突关节的侵扰,更好的维持复位。

关键词：脊柱骨折外科手术微创性骨折固定术

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Profiling the m^(6)A-regulated RNA expression patterns and alternative splicing features in esophageal carcinoma

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Genes & Diseases 2023年第5期10卷 1812-1815页

作者： Lingsuo Kong fei Gao Fangfang Zhao Ran Xia Cifeng Cai Weixin Wang Dabing Huang Zhenyu Li Qiyi Yi Chunbao Zang Youguang pu Department of Anesthesiology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230031China Department of Radiology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230031China Department of Cancer Epigenetics Program The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230031China College of Life and Environmental Science Wenzhou UniversityWenzhouZhejiang 325035China Hangzhou Cosmos Wisdom Biotech Co. Ltd.5th FloorBlock D198 Qidi RoadXiaoshan DistrictHangzhouZhejiang 311200China Department of Oncology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230031China Department of Provincial Clinical College Wannan Medical CollegeWuhuAnhui 241002China Department of Nuclear Medicine School of Basic Medical SciencesAnhui Medical UniversityHefeiAnhui 230031China Department of Radiation Oncology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230031China

The m^(6)A modification involves almost all aspects of RNA biology,including the alternative splicing of mRNA precursors,mRNA transport and stability,and miRNA processing and regulation of target genes.1,2 Alternative splicing controlling the information storage and RNA translation involves the regulation of various biological processes.3,4,5 Here,we integrated the genomic information of 161 esophageal cancer(EC)samples to comprehensively evaluate the m^(6)A modification patterns and correlated the m^(6)A modification pattern with the prognosis of EC patients,where two distinct m^(6)A modification patterns were *** combined effects of high m^(6)Ascore and low TMB correlated with a better prognosis of EC *** addition,we found an inherent correlation between m^(6)A modification and the occurrence of alternative splicing events in EC ***,we established a scoring system to quantify the m^(6)A modification pattern with RNA alternative splicing events in individual EC patients(Fig.S1).

关键词： esophageal prognosis m^(6)A

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A Case Series of Olfactory Dysfunction in Imported COVID-19 Patients:A 12-Month Follow-Up Study

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Biomedical and Environmental Sciences 2022年第5期35卷 402-411页

作者： WANG Ni yang Ming Bo yang pu Ye CHEN Ren Bo HUANG fei SHI Nan Nan MA Yan ZHANG Yan XU You LIU Si Hong LU Heng Yi FU Qing Qing FAN Yi Pin KAN Hong Min WANG Xiao Hong GUO Ya Ling National Center for Tuberculosis Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206China Hepatology Department of TCM Xi’an NO.8 HospitalXi’an 710061ShaanxiChina Department of Integrated Chinese and Western Medicine Xi’an NO.8 HospitalXi’an 710061ShaanxiChina Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China Department of Infection Xi’an NO.8 HospitalXi’an 710061ShaanxiChina Institute of Information on Traditional Chinese Medicine China Academy of Chinese Medical SciencesBeijing 100700China

Objective The scientific community knows little about the long-term influence of coronavirus disease2019(COVID-19) on olfactory dysfunction(OD). With the COVID-19 pandemic ongoing worldwide, the risk of imported cases remains high. In China, it is necessary to understand OD in imported *** A prospective follow-up design was adopted. A total of 11 self-reported patients with COVID-19 and OD from Xi’an No. 8 Hospital were followed between August 19, 2021, and December 12, ***, clinical characteristics, laboratory and radiological findings, and treatment outcomes were analyzed at admission. We surveyed the patients via telephone for recurrence and sequelae at the1-, 6-, and 12-month *** Eleven patients with OD were enrolled;of these, 54.5%(6/11) had hyposmia and 45.5%(5/11)had anosmia. 63.6%(7/11) reported OD before or on the day of admission as their initial symptom;of these, 42.9%(3/7) described OD as the only symptom. All patients in the study received combined treatment with traditional Chinese medicine and Western medicine, and 72.7%(8/11) had partially or fully recovered at discharge. In terms of OD recovery at the 12-month follow-up, 45.5%(5/11) reported at least one sequela, 81.8%(9/11) had recovered completely, 18.2%(2/11) had recovered partially, and there were no recurrent *** Our data revealed that OD frequently presented as the initial or even the only symptom among imported cases. Most OD improvements occurred in the first 2 weeks after onset, and patients with COVID-19 and OD had favorable treatment outcomes during long-term follow-up. A better understanding of the pathogenesis and appropriate treatment of OD is needed to guide clinicians in the care of these patients.

关键词： COVID-19 Olfactory Imported cases Hyposmia Anosmia Follow-up

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