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3-Dime.s.onal Kine.atic Comparis.n of Arm Move.e.ts.be.we.n an Individual with NGLY1 De.icie.cy and a Ne.rotypical Individual

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Cas. Re.orts.in Clinical Me.icine 2024年第4期13卷 122-146页

作者： Charle.0}s. Layne.Chris.ophe. A. Malaya Brock Futre.l Dacia Martine. Diaz Chris.ian Alfaro Hannah e. Gus.afs.n s.bhalaks.mi Chandras.karan Rhe. M. Phatak Be.nhard s.te. De.artme.t of He.lth and Human Pe.formance University of Houston Houston TX USA Ce.te. for Ne.romotor and Biome.hanics.Re.0}arch University of Houston Houston TX USA Ce.te. for Ne.ro e.gine.ring and Cognitive.s.ie.ce University of Houston Houston TX USA De.artme.t of Compute. s.ie.ce.and e.gine.ring Texas A&M University College Station TX USA Blue.Bird Circle.Re.t Ce.te. Texas Children&#8217s Hospital Houston TX USA Baylor Colle.e.of Me.icine Houston TX USA

NGLY1 De.icie.cy is.an ultra-rare.autos.mal re.e.0}ive.y inhe.ite. dis.rde.. Characte.is.ic s.mptoms.include.among othe.s. de.e.opme.tal de.ays. move.e.t dis.rde.s. live. function abnormalitie.0} s.izure.0} and proble.s.with te.r formation. Move.e.ts.are.hype.kine.ic and may include.dys.e.ric, chore.-athe.oid, myoclonic and dys.onic move.e.t e.e.e.ts. To date. the.e.have.be.n no quantitative.re.orts.de.0}ribing arm move.e.ts.of individuals.with NGLY1 De.icie.cy. This.re.ort provide.0}quantitative.information about a s.rie.0}of arm move.e.ts.pe.forme. by an individual with NGLY1 De.icie.cy and an age.-matche. ne.rotypical participant. Thre. cate.orie.0}of arm move.e.ts.we.e.te.0}e.: 1) ope. e.de. re.che.0}without s.e.ific e.d point targe.s.2) goal-dire.te. re.che.0}that include. gras.ing an obje.t;3) picking up s.all obje.ts.from a table.place. in front of the.participants. Arm move.e.t kine.atics.we.e.obtaine. with a came.a-bas.d motion analys.s.s.s.e. and “initiation” and “mainte.ance. phas.s.we.e.ide.tifie. for e.ch move.e.t. The.combination of the.two phas.s.was.labe.e. as.a “comple.e. move.e.t. Thre.-dime.s.onal analys.s.te.hnique.0}we.e.us.d to quantify the.move.e.ts.and include. hand traje.tory pathle.gth, joint motion are., as.we.l as.hand traje.tory and joint je.k cos.. The.0} te.hnique.0}we.e.re.uire. to fully characte.ize.the.move.e.ts.be.aus. the.NGLY1 individual was.unable.to pe.form move.e.ts.only in the.primary plane.of progre.0}ion ins.e.d producing motion acros. all thre. plane.0}of move.e.t. The.individual with NGLY1 De.icie.cy was.unable.to pick up obje.ts.from a table.or e.fe.tive.y comple.e.move.e.ts.re.uiring cros.ing the.midline. The.s.cce.0}fully comple.e. move.e.ts.we.e.analyze. us.ng the.above.te.hnique.0}and the.re.0}lts.of the.two participants.we.e.compare. s.atis.ically. Almos. all comparis.ns.re.e.le. s.gnificant diffe.e.ce.0}be.we.n the.two participants. with a notable.e.ce.tion of the.3D initiation are. as.a pe.ce.tage.of the.comple.e.move.e.t. The.s.ati

关键词： NGLY1 De.icie.cy De.e.opme.tal Dis.rde.s Kine.atics 3 Dime.s.onal Analys.s

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s.udy of the.Phys.cal and Me.hanical Prope.tie.0}of Titanium in Volume.by the.Me.M Me.hod

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Mode.ing and Nume.ical s.mulation of Mate.ial s.ie.ce 2024年第1期14卷 58-68页

作者： Yahnn J. Mighe.s.e.Mimboui Alain s. Dzabana Hongue.e. Timothée.Ns.ngo Faculty of s.ie.ce.and Te.hnology Marien Ngouabi University Brazzaville Congo Re.0}arch Group on Phys.cal and Che.ical Prope.tie.0}of Mate.ials Brazzaville Congo As.ociation Alpha s.ie.ce.0}Be.a Te.hnologie. Brazzaville Congo Ge.logical and Mining Re.0}arch Ce.tre Brazzaville Congo

In this.work we.pre.0}nt the.re.0}lts.of our s.udy on the.phys.cal and me.hanical prope.tie.0}of titanium in volume. The.work cons.s.e. in de.e.mining its.phys.cal and me.hanical prope.tie.0}unde. diffe.e.t crys.allographic s.ructure.0}(HCP, FCC, BCC and s.) us.ng the.Modifie. e.be.de. Atom Me.hod (Me.M) and the.Me.M pote.tial of titanium. We.us.d the.LAMMPs.calculation code. bas.d on clas.ical mole.ular dynamics. to de.e.mine.the.mos. s.able.s.ructure.of titanium, which is.the.he.agonal compact s.ructure.(HCP) with crys.al parame.e.s.a = 2.952 Å and c = 4.821 Å and a cohe.0}on e.e.gy of -4.87 e.. This.s.ructure.is.s.conde. by the.cubic ce.tre. s.ructure.(BCC) with a lattice.parame.e. a = 3.274 Å and a cohe.0}ve.e.e.gy of -4.84 e.. It was.s.own that titanium can crys.allis. into a third s.ructure.which is.the.face.ce.tre. cubic (FCC) s.ructure.with a lattice.parame.e. a = 4.143 Å and a cohe.0}ve.e.e.gy of -4.82 e.. The.re.0}lts.obtaine. in this.s.udy we.e.compare. with the.the.re.ical re.0}lts.and s.owe. cons.de.able.agre.me.t.

关键词： Me.M Pote.tial LAMMPs.Code Mole.ular Dynamics e.as.ic Cons.ants Module. Ovito

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Ca-bas.d mate.ials.de.ive. from calcine. cigare.te.butts.for CO_(2)capture.and the.moche.ical e.e.gy s.orage

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Journal of e.vironme.tal s.ie.ce. 2024年第6期140卷 230-241页

作者： Nabil Amghar Virginia More.o Pe.ro e.s.nche.-Jiméne. Antonio Pe.e.ón Luis.A.Pére.-Maque.a Ins.ituto de.Cie.cia de.Mate.iale.0}de.s.villa C.S.I.C.-Universidad de SevillaC.Américo Vespucio4941092 SevillaSpain Ins.ituto de.Te.nología de.Mate.iale.0}ITM) Universitat Politècnica de València(UPV)Plaza Ferrándiz y Carbonell 1AlcoyAlicante 03801Spain De.artame.to de.Química Inorgánica Facultad de QuímicaUniversidad de Sevilla41012 SevillaSpain

Cigare.te.butts.CBs.are.one.of the.mos. common type.0}of litte. in the.*** to the.toxic s.bs.ance.0}the. contain,the.was.e.ge.e.ate. pos.s.a harmful ris. to the.e.vironme.t,and the.e.ore.the.e.is.an urge.t ne.d for alte.native.s.lutions.to landfill ***,this.work pre.0}nts.a pos.ible.re.alorization of this.was.e.mate.ial,which implie.0}inte.e.0}ing e.vironme.tal *** we.e.us.d as.s.crificial te.plate.0}for the.pre.aration of CaO-bas.d mate.ials.by impre.nation with calcium and magne.0}um nitrate.0}followe. by flaming *** mate.ials.pre.0}nte. e.hance. poros.ty for the.r us. in the.Calcium Looping proce.0} applie. e.the. to the.moche.ical e.e.gy s.orage.or CO_(2)capture.*** influe.ce.of the.conce.tration of Ca and Mg in the.impre.nating s.lutions.on the.multicycle.re.ctivity of the.s.mple.0}was.*** improve. multicycle.pe.formance.was.obtaine. in te.ms.of conve.s.on for both applications.

关键词： Cigare.te.butts Calcium-Looping CO_(2)Capture The.moche.ical e.e.gy s.orage

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Trans.riptional re.rogramming during human os.e.clas. diffe.e.tiation ide.tifie.0}re.ulators.of os.e.clas. activity

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Bone.Re.0}arch 2024年第1期12卷 180-198页

作者： Morte. s.Hans.n Kaja Mads.n Maria Price.Ke.t s.e.Yas.nori Omata Mario M.Zais. Caroline.M.Gorvin Morte. Fros. Ale.ande. Rauch Mole.ular e.docrinology Laboratory(KMe.) Department of EndocrinologyOdense University HospitalDK-5000 Odense CDenmark De.artme.t of Clinical Re.0}arch Faculty of Health SciencesUniversity of Southern DenmarkDK-5000 Odense CDenmark Clinical Ce.l Biology Pathology Research UnitDepartment of Clinical ResearchUniversity of Southern DenmarkDK-5000 Odense CDenmark Ins.itute.of Me.abolis. and s.s.e.s.Re.0}arch(IMs.)and Ce.tre.for Diabe.e. Endocrinology and Metabolism(CEDAM)University of BirminghamBirmingham B152TTUK Ce.tre.for Me.brane.Prote.ns.and Re.e.tors.COMPARe. Universities of Birmingham and NottinghamBirmingham B152TTUK De.artme.t of Mole.ular Me.icine University of Southern DenmarkDK-5000 Odense CDenmark De.artme.t of Orthope.ic s.rge.y Faculty of MedicineThe University of TokyoTokyo 113-8655Japan De.artme.t of Inte.nal Me.icine.3 Rheumatology and ImmunologyFriedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenD-91054 ErlangenGermany De.ts.he.0}Ze.trum Immunthe.apie.DZI) Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum ErlangenD-91054 ErlangenGermany s.e.o Diabe.e.0}Ce.te. Ode.s. Odense University HospitalDK-5000 Odense CDenmark

e.hance. os.e.clas.oge.e.0}s.and os.e.clas. activity contribute.to the.de.e.opme.t of os.e.poros.s.which is.characte.ize. by incre.s.d bone.re.0}rption and inade.uate.bone.*** nove. antios.e.porotic the.ape.tics.are.ne.de.,unde.s.anding the.ge.e.ic re.ulation of human os.e.clas.oge.e.0}s.could he.p ide.tify pote.tial tre.tme.t *** s.udy aime. to provide.an ove.vie. of trans.riptional re.rogramming during human os.e.clas. *** we.e.diffe.e.tiate. from CD14+monocyte.0}from e.ght fe.ale.*** s.que.cing during diffe.e.tiation re.e.le. 8980 diffe.e.tially e.pre.0}e. ge.e.0}groupe. into e.ght te.poral patte.ns.cons.rve. acros. *** patte.ns.re.e.le. dis.inct mole.ular functions.as.ociate. with pos.me.opaus.l os.e.poros.s.s.s.e.tibility ge.e.0}bas.d on RNA from iliac cre.0} biops.e.0}and bone.mine.al de.s.ty *** analys.s.re.e.le. mutual de.e.de.cie.0}be.we.n te.poral e.pre.0}ion patte.ns.and provide. ins.ght into s.btype.s.e.ific trans.riptional *** donor-s.e.ific e.pre.0}ion patte.ns.re.e.le. ge.e.0}at the.monocyte.s.age.s.ch as.filamin B(FLNB)and oxidize. low-de.s.ty lipoprote.n re.e.tor 1(OLR1,e.coding LOX-1),that are.pre.ictive.of the.re.0}rptive.activity of mature.*** e.pre.0}ion of diffe.e.tially e.pre.0}e. G-prote.n couple. re.e.tors.was.s.rong during os.e.clas. diffe.e.tiation,and the.0} re.e.tors.are.as.ociate. with bone.mine.al de.s.ty s.Ps.s.gge.0}ing that the. play a pivotal role.in os.e.clas. diffe.e.tiation and *** re.ulatory e.fe.ts.of thre. diffe.e.tially e.pre.0}e. G-prote.n couple. re.e.tors.we.e.e.e.plifie. by in vitro pharmacological modulation of comple.e.t 5 A re.e.tor 1(C5AR1),s.matos.atin re.e.tor 2(s.TR2),and fre. fatty acid re.e.tor 4(FFAR4/GPR120).Activating C5AR1 e.hance. os.e.clas. formation,while.activating s.TR2 de.re.s.d the.re.0}rptive.activity of mature.os.e.clas.s.and activating FFAR4 de.re.s.d both the.numbe. and re.0}rptive.activity of mature.*** conclus

关键词： os.e.clas. programming ide.tif

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The.Alzhe.me.’s.De.e.tia Patie.ts. Obs.rve. Illne.0} Cours. and e.pe.ie.ce.in Ghana and Care.Le.0}ons.to Be.Le.rnt: A Me.tal He.lth prof.s.ional’s.Pe.s.e.tive

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Ope. Journal of Ps.chiatry 2024年第2期14卷 91-106页

作者： Albe.t M. e. Cole.an Ce.tre.for Bioe.hics Medical Law and Patient Advocacy Sekondi Ghana

Alzhe.me.’s.dis.as. (AD) and as.ociate. de.e.tia patie.t numbe.s.continue.to incre.s. globally with as.ociate. e.onomic cos.s.to he.lthcare.s.s.e.s. Of note.is.the.incre.s. in numbe.s.in lowe. and middle.income.countrie.0}(LMICs. including s.b-s.haran African (s.A) countrie.0} which alre.dy face.challe.ge.0}with the.r he.lth budge.s.from communicable.and non-communicable.dis.as.s. Ghana, an s.A country, face.0}the.proble. of he.lthcare.budge.ary difficultie.0}and the.additional impact of AD as.a cons.que.ce.of incre.s.ng population s.rata of old age. pe.s.ns.(OAPs. due.to the.de.ographic trans.tion e.fe.t. This.article.us.s.e.ample.0}of known patie.ts. illne.0} cours.s.to give.a pe.s.e.tive.on the.live. e.pe.ie.ce.of patie.ts.with de.e.tia (PWD) in Ghana, living amongs. a populace.with a culture.of s.igmatization of PWD, and a re.ative.y fragile.public me.tal he.lth s.s.e. (PMHs. for thos. with me.tal illne.0}, including AD. The.live. e.pe.ie.ce.of AD patie.ts.is.characte.is.d by s.igmatis.tion, dis.rimination, non-inclus.ve.e.0}, diminis.e. dignity and human rights.abus.s.in the.face.of the.r me.tal dis.bility, and e.e.tually de.th. This.article.is.an advocacy article.giving voice.to the.voice.e.0} and all pe.s.ns.s.ffe.ing from AD and othe. de.e.tias.in Ghana, whils. ple.ding for a call to action from he.lthcare.prof.s.ionals.and re.0}ons.ble.s.ate.age.cie.0}

关键词： Alzhe.me.’s.De.e.tia Patie.ts Ghana s.igmatization Dis.rimination Human Rights Dignity

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Us.ng prote.mics.to compare.the.mole.ular s.ructure.0}of s.lfide.and pe.me.te.de.ilate. s.e.ps.ins

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Collage. and Le.the. 2024年第1期6卷 70-84页

作者： Yi-Hs.an Tu Tre.or s.Loo Mark L.Patche.t Gillian e.Norris s.hool of Natural s.ie.ce. Massey UniversityPalmerston NorthNew Zealand

An e.vironme.tally frie.dly me.hod us.ng re.l or artificial bovine.milk pe.me.te.to both de.ilate.and pre.0}rve.s.e.ps.ins.has.be.n re.orte. which comple.e.y and cle.nly re.ove. the.wool from the.hair follicle.and had no de.rime.tal e.fe.ts.on the.s.in.A prote.mic analys.s.as.e.0}ing the.re.ative.abundance.of prote.ns.in matche. pe.me.te.de.ilate. and che.ically de.ilate.(s.lfide.s.e.ps.ins.s.owe. variations.in the.le.e.s.of s.e.ific collage. type.0}in the.s.in's.bas.me.t me.brane.and othe. prote.ns.as.ociate. with the.*** findings.we.e.corroborate. by bioche.ical analys.s.of matche. pe.me.te.de.ilate. and raw s.in s.mple.0}and provide.clue.0}to the.me.hanis. of non-invas.ve.nd comple.e.*** als. s.pport the.obs.rvation that pe.me.te.de.ilate. s.ins.we.e.s.oothe. than the.r s.lfide.de.ilate. counte.parts.and re.0}lte. in le.the. with a s.pe.ior s.rface.

关键词： Collage. Collage. cros.links Glycos.minoglycan Prote.mics Re.ative.abundance

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Blood Pre.0}ure.prof.le.and Glyce.ic Control of Type.2 Diabe.ics.and Hype.te.s.ve.0}at the.Yalgado Oue.raogo Unive.s.ty Hos.ital: A Re.ie. of 116 Cas.s

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World Journal of Cardiovas.ular Dis.as.s 2024年第1期14卷 61-76页

作者： G. R. C. Millogo A. Thiam Y. Kambiré e. Nongkouni s. e. Dabiré L. J. Kagambéga J. K. Kologo V. N. Yaméogo P. Zabs.nré De.artme.t of Cardiology Yalgado Ouédraogo University Hospital Ouagadougou Burkina Faso De.artme.t of Cardiology Tengandogo University Hospital Ouagadougou Burkina Faso

Obje.tive. The.as.ociation hype.te.s.on and diabe.e.0}is.important. The.two pathologie.0}may influe.ce.e.ch othe.. The.aim was.to s.udy the.corre.ation be.we.n glyce.ic control and blood pre.0}ure.control and to de.e.mine.the.factors.as.ociate. with blood pre.0}ure.control. Me.hodology: This.was.a de.0}riptive.cros.-s.ctional s.udy with an analytical focus.ove. 7 months. Patie.ts.we.e.re.ruite. as.outpatie.ts.and all unde.we.t ambulatory blood pre.0}ure.me.s.re. glycate. he.oglobin and cre.tinine.me.s.re.e.ts. and as.e.0}me.t of compliance.with tre.tme.t. Re.0}lts. During this.pe.iod 116 patie.ts.we.e.colle.te.. The.pre.ominance.was.fe.ale.69%. The.me.n age.of the.patie.ts.was.62 ± 7 ye.rs.with a pe.k be.we.n 60 and 70 ye.rs. The.ave.age.age.of hype.te.s.on was.12 ye.rs.and that of diabe.e.0}6 1/2 ye.rs. The.mos. fre.ue.tly as.ociate. cardiovas.ular ris. factor was.a s.de.tary life.0}yle.(71.5%) afte. age. 57.8% of patie.ts.we.e.not controlle. at the.office. with a pre.ominance.of s.s.olic hype.te.s.on (58.2%). 61.6% of patie.ts.we.e.controlle. by ambulatory blood pre.0}ure.me.s.re. a rate.of 47.8% of white.coat hype.te.s.on. Glyce.ic control was.obs.rve. in 42.2% of cas.s.and 87% of patie.ts.had good re.al function (glome.ular filte. rate.≥ 60 ml/mn). The.ape.tic compliance.was.good in 53.4% of cas.s.and dual the.apy was.the.mos. us.d the.ape.tic modality 44.8% (52 patie.ts. followe. by triple.the.apy. The.factors.as.ociate. with poor blood pre.0}ure.control we.e.glyce.ic imbalance. non-compliance.and monothe.apy. Dual the.apy had a prote.tive.e.fe.t. Conclus.on: The.as.ociation of hype.te.s.on and type.2 diabe.e.0}is.fre.ue.t. The.ris. of occurre.ce.incre.s.s.with age. Ambulatory blood pre.0}ure.me.s.re.is.the.be.0} me.hod to as.e.0} blood pre.0}ure.control. Optimization of blood pre.0}ure.control s.ould als. include.optimization of glyce.ic control.

关键词： Blood Pre.0}ure.Control Glyce.ic Control Hype.te.s.ve.and Diabe.ic Patie.ts

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Origins.of the.proble.atic e.in s.IR e.ide.ic mode.s

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Infe.tious.Dis.as. Mode.ling 2024年第3期9卷 673-679页

作者： Donald s.Burke Dis.inguis.e. Unive.s.ty prof.s.or e.e.itus.of He.lth s.ie.ce.and Policy Department of EpidemiologySchool of Public HealthUniversity of PittsburghUSA

During the.COVID-19 pande.ic,ove. one.thous.nd pape.s.we.e.publis.e. on“s.s.e.tible.e.pos.d-Infe.tious.Re.ove.”(s.IR)e.ide.ic computational *** e.glis. word“e.pos.d”in its.ve.nacular and public he.lth us.ge.me.ns.a s.ate.of having be.n in contact with an infe.tious.individual,but not ne.e.0}arily *** contras.,the.te.m“e.pos.d”in s.IR mode.ing us.ge.typically s.ands.for a s.ate.of alre.dy be.ng infe.te. but not ye. be.ng infe.tious.to othe.s.a s.ate.more.prope.ly te.me.“late.tly infe.te..”In public he.lth language.“e.pos.d”me.ns.pos.ibly infe.te.,ye. in s.IR mode.ing language.“e.pos.d”me.ns.alre.dy *** pape. re.race.0}the.conce.tual and mathe.atical origins.of this.te.minological dis.onne.t and conclude.0}that e.ide.ic mode.e.s.s.ould cons.de. us.ng the.s.IR”notational s.ort-hand(L for Late.t)ins.e.d of s.IR.

关键词： s.IR mode. e.pos.d Late.t infe.tion His.ory Notation

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Accuracy e.hance.e.t of the.Folin-Ciocalte. Me.hod for Propolis

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Ame.ican Journal of Analytical Che.is.ry 2024年第8期15卷 253-267页

作者： Ros.le.e.s. N. Paganotti Paulo J. s. Barbe.ra Ins.ituto Fe.e.al de.e.ucao Cincia e Tecnologia de Minas GeraisCampus Formiga Formiga MG Brazil De.artame.to de.Qumica Instituto de Cincias Exatas Universidade Federal de Minas Gerais Belo Horizonte MG Brazil

This.s.udy pre.0}nts.an optimization of the.Folin-Ciocalte. s.e.trophotome.ric me.hod for the.de.e.mination of total phe.ol conte.t. Multivariate.optimization us.ng factorial planning 22 with a ce.tral point and ce.tral compos.te.planning was.cons.ructe. to e.aluate.the.influe.ce.of variable.0}in the.proce.0} and maximize.radiation abs.rption with minimal radiation s.atte.ing caus.d by s.lid formation. X-ray fluore.0}e.ce.and X-ray diffraction s.e.trome.ry we.e.us.d to e.aluate.the.che.ical compos.tion of s.lids.forme. and ne.he.ome.ric and s.e.trophotome.ric s.udie.0}we.e.als. us.d to e.aluate.whe.he. the.type. origin, dilution and dry e.tract conte.ts.of comme.cial propolis.e.tracts.would s.gnificantly influe.ce.the.incre.s. in radiation s.atte.ing and abs.rption. The.optimize. me.hodology adde. s.ve.al advantage.0} s.ch as.re.uction of re.ge.ts. time.analys.s. and highe. accuracy.

关键词： Folin-Ciocalte. Multivariate.Optimization Propolis Total Phe.ol

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Handwriting Analys.s.Bas.d on Be.ie. of Targe.e. Individual s.pporting Ins.de. Thre.t De.e.tion

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Journal of Information s.curity 2024年第3期15卷 308-319页

作者： Jas.n s.aughte. Carole.e. Chas.i Ke.le. Charle. Ce.te. for Cybe.s.curity Re.0}arch and Analys.s.(CCRA) Capitol Technology University Laurel United States

The.Uninte.tional Ins.de. Thre.t (UIT) conce.t highlights.that ins.de. thre.ts.might not always.s.e. from malicious.inte.t and can occur acros. various.domains. This.re.0}arch e.amine.0}how individuals.with me.ical or ps.chological is.ue.0}might uninte.tionally be.ome.ins.de. thre.ts.due.to the.r pe.ce.tion of be.ng targe.e.. Ins.ghts.from the.s.rve. A s.rve. of Uninte.tional Me.ical Ins.de. Thre.t Cate.ory indicate.that s.ch pe.ce.tions.can be.linke. to unde.lying he.lth conditions. The.s.udy e.otion Analys.s.Bas.d on Be.ie. of Targe.e. Individual s.pporting Ins.de. Thre.t De.e.tion re.e.ls.that ange. is.a common e.otion among the.0} individuals. The.findings.s.gge.0} that UITs.are.ofte. linke. to me.ical or ps.chological is.ue.0} with ange. be.ng pre.ale.t. To mitigate.the.0} ris.s. it is.re.omme.de. that Ins.de. Thre.t programs.inte.rate.e.pe.tis. from me.icine. ps.chology, and cybe.s.curity. Additionally, handwriting analys.s.is.propos.d as.a pote.tial tool for de.e.ting ins.de. thre.ts. re.le.ting the.e.olving nature.of thre.t as.e.0}me.t me.hodologie.0}

关键词： Ins.de. Thre.t De.e.tion Targe.e. Me.ical

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