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Classical Hodgkin＇s Lymphoma Presenting as Acute Hepatic Failure One Case Report

Clinical oncology and cancer researeh 2010年第6期7卷 373-376页

作者： pradipta guha Shivesh Shanker Sahai Sekhar Mukherjee Sanjoy Kumar Chatterjee Department of cardiology G.B. Pant Hospital New Delhi 110002 India. Department of General Medicine Medica College Kolkata-700073 West Bengal India.

A 20-year-old boy presenting daily febrile episodes was suspected to have developed acute hepatic failure. Serologic tests ruled out infectious and autoimmune causes apart from drug toxicity. During clinical examinations, he was found to have generalized enlarged lymph nodes that were then taken biopsy. It was diagnosed as classical Hodgkin＇s lymphoma based on histological examination of the lymph node. A bone marrow biopsy showed marrow infiltration by Hodgkin＇s lymphoma with hemophagocytosis and secondary myelofibrosis. A percutaneous liver biopsy demonstrated hepatic involvement of the same disease. After an extensive work-up, the cause of liver failure was figure out to be only attributed to the involvement of the lymphoma. Hodgkin＇s lymphoma as a cause of hepatic failure is rare and young patients diagnosed as Hodgkin＇s lymphoma causing hepatic failure has been reported very rarely so far.

关键词： Hodgkin's disease bone marrow liver failure acute.

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Non-Classical Hodgkin＇s Lymphoma Presenting As Cauda Equina Syndrome a Rare presentation： One Case Report

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Clinical oncology and cancer researeh 2010年第5期7卷 322-325页

作者： pradipta guha Debasis Sarkar Indranil Thakur Partha Sardar Sekhar Mukherjee Sanjoy Kumar Chatterjee Department of cardiology G.B.Pant HospitalNew Delhi Jawaharlal Nehru Marg 110002New Delhi India. Department of General Medicine Medical College Kolkata 88 College Street Kolkata 700073 West Bengal India. Department of General Medicine Lal Bahadur Shastri Hospital Khichripur New Delhi 110091 India.

Nodular lymphocyte predominant Hodgkin＇s disease occurs in 5% of all cases of Hodgkin＇s disease. It occurs more commonly in male. Only 5% of all Hodgkin＇s lymphoma cases develop spinal cord compression and in only 0.2% cases, spinal cord compression occurs as the initial presentation. So our case is rare both in the form of the unique variety of Hodgkin＇s disease and also in the form of presentation.

关键词： Hodgkin's disease non-classical variety cauda equina syndrome.

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Bronchogenic Carcinoma in a Scleroderma Patient with Multiple Metastases： One Case Report

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Clinical oncology and cancer researeh 2010年第3期7卷 214-216页

作者： pradipta guha Shivesh Shanker Sahai Debasis Sarkar Partha Sardar Anup Singh Bipiab Mandal Bidyut Kumar Das Sanjoy Kumar Chatterjee Department of General Medicine Medica College Kolkata 700083 West Bengal India.

IntroductionThe association between pulmonary interstitial fibrosis and the development of bronchogenic carcinoma in a patient with scleroderma has been reported rarely. It is hypothesized that intense epithelial proliferation that is accompanied by the .brotic process increases the occurrence of carcinomatous changes. We report the case of a pa-tient who presented with 3-year history of Raynaud＇s phenomenon, gradual tightening of the skin which was ignored by the patient and her family members, and a 2-week history of severe respiratory dis-tress with left shoulder and upper back pain followed by the develop-ment of paraparesis. After a series of examinations, the patient was diagnosed with scleroderma and simultaneously with bronchogenic carcinoma and multiple distant metastases.

关键词： scleroderma bronchogenic carcinoma metastasis.

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Primary Pleural Extranodal Non-Hodgkin＇s Lymphoma Presenting As Pleural Thickening-A Case Report

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Clinical oncology and cancer researeh 2011年第1期8卷 47-50页

作者： pradipta guha Debasis Sarkar Arindam Ray Indranil Thakur Sekhar Mukherjee Sanjoy Kumar Chatterjee RMO Cum Clinical Tutor Department of General Medicine Calcutta National Medical College Kolkata 700014 West Bengal India Department of General Medicine Medical College Kolkata 700073 West Bengal India

Primary pleural lymphoma is a rare entity that has been described in association with human immunodeficiency virus （HIV） infection or pyothorax. This paper reports on a 27 year old man with no history of HIV infection or pyothorax who presented with progressive dyspnea and heaviness of *** radiography revealed complete opacification of the left hemithorax, and contrast enhanced computed tomography showed large left pleural effusion and homogeneous, extensive thickening of the parietal pleura. CT guided biopsy of thickened pleura is suggestive of non-Hodgkin＇s lymphoma-T cell lymphoblastic variety. Physicians should be aware of this rare location of primary pleural lymphoma manifested by thickening of the pleura.

关键词： non-Hodgkin's lymphoma T cell lymphoblastic type lymphoma extranodal NK-T-cell

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